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The map label for this gene is yycG [H]

Identifier: 187935541

GI number: 187935541

Start: 1965078

End: 1966415

Strand: Reverse

Name: yycG [H]

Synonym: CLL_A1865

Alternate gene names: 187935541

Gene position: 1966415-1965078 (Counterclockwise)

Preceding gene: 187933012

Following gene: 187934523

Centisome position: 51.74

GC content: 25.71

Gene sequence:

>1338_bases
ATGACTTTAACCATTTTTACAATATCAATATTTGTTAAAAAAACATTTCAAACAGAGTTTGGCAAGTATGTTGATGATAG
CAATAAAACAGAAGTTGAACATTTAGTTTTCGACTTAAAAAATATATATAAAGATAATAATTGGGATGTAGAATTAATTG
AACAATTAGGCCAAGATGCTATAAAGAAGGGTATTGCATTAGAAATATATAGTTATGATAATACTTCAGTATGGAGTGTT
TTTAATGATGAACAAATTTTATCTAATGAAATATTAAGTAGCATTAGGGAAAATATGATGAGTATTGAGGAAAATTGGAA
TAGTAATTTAAAAGATTATAAGATAAATATATATGATGAAAATGAAAATATAGTAGGGTATGAGAATATAATTCACTATG
AATCAGTTTATTACATGGAAAATGACATGGAGTTTTTAAGTATAATTAATAAGTTTATGGGTATAACAAGCATAATTTCA
ATTGGTAGCATTATCTTAATATCAATCTTAATATCTAAAGTATTATCTAATTCTATGGAGAAAGTATCTAAAATGGCAAA
GGTAATAGAGAAGGGGAAATATAAAAGCAATTTAGATTATAAAAGTAATATAAAAGAAGTAGATGATCTTATACTTGCTA
TAAATAGCTTGTCAGTCAAATTGAATGATGAAGAGATTCTAAGAAAAAGATTAACTACAGATATAGCACATGAGTTAAGA
ACACCTCTTACAAGCATTCAAGGACATTTAGATACATTAATTGATGGCGTTTGGGAACCGACTTCTGAAAGACTTATAAG
CATTAGAGAAGAAGTGTCAAGATTAGGTGACCTAGTAGGTGAGTTAAGAAAACTTTCAAAATTTGATATTGAAAAGAACA
TTTTAAATAAGACTGAGGTTAATTTAAAAGAGCTTATACAAAATATAATTTATAATTATGAAAGTAAGGCTTTAGAGAAA
CAAATTACTATAGAGAGTAACCTTAAAGATATATTTATAAATGTAGATAAAAATCAATTTTCGCAAGTTTTAATAAATAT
TTTATCTAATGCAATTAAGTATACTAATATAGGTGGTAGAGTTGAATTAAATATGTATGAAGACATCGATAATGTAAATA
TAAGTATTAAAGATACAGGATGTGGAATTCCTAAGGAAGATATAAAGAATATATTTGAAAGGTTTTATAGAGTTGATAGA
TCTAGAAATAAAAAGACAGGTGGAATAGGGGTTGGACTTACCATAGCTCAAAGTATAATAAATGCTCATAATGGGGAAAT
TATAGTTAAGAGTGAACTGAATAAAGGGACAGAGTTTATAATTAAACTTTCTAAATAA

Upstream 100 bases:

>100_bases
AAGATAATAAAAACTATTTATGGGGTAGGATATAGATTTGAATTACAAGATTAAAAGTATATCATTAAGAAATACAATTT
TAATATCATTTACTATAATC

Downstream 100 bases:

>100_bases
GTATATATTAAATGATTATTTAATGAAAAAGTATTCAATAAGATATAGAGTACTTTTTTATTTTTTTATTAATATAAAGA
AAAGTAAGATTAGACTTAAT

Product: alkaline phosphatase synthesis sensor protein PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTLTIFTISIFVKKTFQTEFGKYVDDSNKTEVEHLVFDLKNIYKDNNWDVELIEQLGQDAIKKGIALEIYSYDNTSVWSV
FNDEQILSNEILSSIRENMMSIEENWNSNLKDYKINIYDENENIVGYENIIHYESVYYMENDMEFLSIINKFMGITSIIS
IGSIILISILISKVLSNSMEKVSKMAKVIEKGKYKSNLDYKSNIKEVDDLILAINSLSVKLNDEEILRKRLTTDIAHELR
TPLTSIQGHLDTLIDGVWEPTSERLISIREEVSRLGDLVGELRKLSKFDIEKNILNKTEVNLKELIQNIIYNYESKALEK
QITIESNLKDIFINVDKNQFSQVLINILSNAIKYTNIGGRVELNMYEDIDNVNISIKDTGCGIPKEDIKNIFERFYRVDR
SRNKKTGGIGVGLTIAQSIINAHNGEIIVKSELNKGTEFIIKLSK

Sequences:

>Translated_445_residues
MTLTIFTISIFVKKTFQTEFGKYVDDSNKTEVEHLVFDLKNIYKDNNWDVELIEQLGQDAIKKGIALEIYSYDNTSVWSV
FNDEQILSNEILSSIRENMMSIEENWNSNLKDYKINIYDENENIVGYENIIHYESVYYMENDMEFLSIINKFMGITSIIS
IGSIILISILISKVLSNSMEKVSKMAKVIEKGKYKSNLDYKSNIKEVDDLILAINSLSVKLNDEEILRKRLTTDIAHELR
TPLTSIQGHLDTLIDGVWEPTSERLISIREEVSRLGDLVGELRKLSKFDIEKNILNKTEVNLKELIQNIIYNYESKALEK
QITIESNLKDIFINVDKNQFSQVLINILSNAIKYTNIGGRVELNMYEDIDNVNISIKDTGCGIPKEDIKNIFERFYRVDR
SRNKKTGGIGVGLTIAQSIINAHNGEIIVKSELNKGTEFIIKLSK
>Mature_444_residues
TLTIFTISIFVKKTFQTEFGKYVDDSNKTEVEHLVFDLKNIYKDNNWDVELIEQLGQDAIKKGIALEIYSYDNTSVWSVF
NDEQILSNEILSSIRENMMSIEENWNSNLKDYKINIYDENENIVGYENIIHYESVYYMENDMEFLSIINKFMGITSIISI
GSIILISILISKVLSNSMEKVSKMAKVIEKGKYKSNLDYKSNIKEVDDLILAINSLSVKLNDEEILRKRLTTDIAHELRT
PLTSIQGHLDTLIDGVWEPTSERLISIREEVSRLGDLVGELRKLSKFDIEKNILNKTEVNLKELIQNIIYNYESKALEKQ
ITIESNLKDIFINVDKNQFSQVLINILSNAIKYTNIGGRVELNMYEDIDNVNISIKDTGCGIPKEDIKNIFERFYRVDRS
RNKKTGGIGVGLTIAQSIINAHNGEIIVKSELNKGTEFIIKLSK

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=240, Percent_Identity=31.25, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786783, Length=303, Percent_Identity=28.0528052805281, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=29.2035398230088, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI145693157, Length=215, Percent_Identity=31.6279069767442, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790346, Length=269, Percent_Identity=26.7657992565056, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787894, Length=261, Percent_Identity=26.8199233716475, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789149, Length=216, Percent_Identity=30.0925925925926, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790861, Length=325, Percent_Identity=24.3076923076923, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788549, Length=218, Percent_Identity=29.3577981651376, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=26.984126984127, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=27.0742358078603, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789403, Length=268, Percent_Identity=26.865671641791, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994928, Length=215, Percent_Identity=28.8372093023256, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082128, Length=303, Percent_Identity=25.0825082508251, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790551, Length=261, Percent_Identity=26.8199233716475, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=27.3109243697479, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788279, Length=300, Percent_Identity=27, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=23.2, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787374, Length=291, Percent_Identity=25.7731958762887, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51135; Mature: 51004

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTIFTISIFVKKTFQTEFGKYVDDSNKTEVEHLVFDLKNIYKDNNWDVELIEQLGQDA
CEEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHH
IKKGIALEIYSYDNTSVWSVFNDEQILSNEILSSIRENMMSIEENWNSNLKDYKINIYDE
HHCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
NENIVGYENIIHYESVYYMENDMEFLSIINKFMGITSIISIGSIILISILISKVLSNSME
CCCEECHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVSKMAKVIEKGKYKSNLDYKSNIKEVDDLILAINSLSVKLNDEEILRKRLTTDIAHELR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHH
TPLTSIQGHLDTLIDGVWEPTSERLISIREEVSRLGDLVGELRKLSKFDIEKNILNKTEV
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCC
NLKELIQNIIYNYESKALEKQITIESNLKDIFINVDKNQFSQVLINILSNAIKYTNIGGR
CHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCE
VELNMYEDIDNVNISIKDTGCGIPKEDIKNIFERFYRVDRSRNKKTGGIGVGLTIAQSII
EEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
NAHNGEIIVKSELNKGTEFIIKLSK
HCCCCCEEEECCCCCCCEEEEEECC
>Mature Secondary Structure 
TLTIFTISIFVKKTFQTEFGKYVDDSNKTEVEHLVFDLKNIYKDNNWDVELIEQLGQDA
EEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHH
IKKGIALEIYSYDNTSVWSVFNDEQILSNEILSSIRENMMSIEENWNSNLKDYKINIYDE
HHCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
NENIVGYENIIHYESVYYMENDMEFLSIINKFMGITSIISIGSIILISILISKVLSNSME
CCCEECHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVSKMAKVIEKGKYKSNLDYKSNIKEVDDLILAINSLSVKLNDEEILRKRLTTDIAHELR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHH
TPLTSIQGHLDTLIDGVWEPTSERLISIREEVSRLGDLVGELRKLSKFDIEKNILNKTEV
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCC
NLKELIQNIIYNYESKALEKQITIESNLKDIFINVDKNQFSQVLINILSNAIKYTNIGGR
CHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCE
VELNMYEDIDNVNISIKDTGCGIPKEDIKNIFERFYRVDRSRNKKTGGIGVGLTIAQSII
EEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
NAHNGEIIVKSELNKGTEFIIKLSK
HCCCCCEEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]