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The map label for this gene is treR [H]

Identifier: 187933880

GI number: 187933880

Start: 1903031

End: 1903744

Strand: Reverse

Name: treR [H]

Synonym: CLL_A1819

Alternate gene names: 187933880

Gene position: 1903744-1903031 (Counterclockwise)

Preceding gene: 187934406

Following gene: 187932933

Centisome position: 50.09

GC content: 25.07

Gene sequence:

>714_bases
ATGGCTAGCAAATATTTTAATATATATAGTGAAATTGCAAATAAAATAGAAAATGGGATATTTAAAGCAAACGATGAAAT
TTCTTCAGAAAGTGATCTTATGAAAGAATATAAAGTTTCTAGAGATACTGCAAGGAAGGCATTAATATTACTTAAGGAAA
ATGGTTATATACAAAAAATAAAAGGACGTCGTTCTTTCGTTTTAGACATAAATAAATTTGATTTTCCTGTGTCAGGTGTA
GTTAGCTTTAAAGAGATTGCAGATAAACTAGGACCTAATTCTAAAACTAAAGTTGAAATTTTAGAATGTATTCATCCAAA
TGAAAGTATGAGTAAAAAACTAGAATTAAATTTTGATGATAAAGTTTGGAAGATAATAAGATCTAGAAGTATTGCAGATG
AAAGAATAATCTTAGATAAGGATTATTTAGTAAAAAAATATGTTGAAAATATTACTGAAGAAATATGTGAAGAGTCTATT
TATAAGTATATTGAAGATGAACTTGGATTAAAAATAGCTTATGCTAAAAAAGAAATAACTGTTCAATTTGCAACGGAAGA
AGATAAAAAATATTTAGATATGAAAAACTTTAATATGATTGTTGTTGTAAAAAGTTATACTTATTTAGATGATACAAGTC
TGTTTCAATATACGGAATCTAGACATAGACCAGATAAGTTTAAATTTGTAGATTTTGCAAGAAGACGTAAATAA

Upstream 100 bases:

>100_bases
GGATTTAAATGATAAAATTTTACTTAGACCATATGAATCTATTGTTTATATTGTTGAGAATTAAGTATATATTATGTTAA
AATGTTTATGGTGATGAATG

Downstream 100 bases:

>100_bases
GTAATTTAAAATGATTTATTAAGTAATTAAAAGCTCTTAGGTGTTATTTTCAGAAATATAACCTAGGAGTTTTTAATTTG
TATTTATAAATATAATTTAG

Product: trehalose operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MASKYFNIYSEIANKIENGIFKANDEISSESDLMKEYKVSRDTARKALILLKENGYIQKIKGRRSFVLDINKFDFPVSGV
VSFKEIADKLGPNSKTKVEILECIHPNESMSKKLELNFDDKVWKIIRSRSIADERIILDKDYLVKKYVENITEEICEESI
YKYIEDELGLKIAYAKKEITVQFATEEDKKYLDMKNFNMIVVVKSYTYLDDTSLFQYTESRHRPDKFKFVDFARRRK

Sequences:

>Translated_237_residues
MASKYFNIYSEIANKIENGIFKANDEISSESDLMKEYKVSRDTARKALILLKENGYIQKIKGRRSFVLDINKFDFPVSGV
VSFKEIADKLGPNSKTKVEILECIHPNESMSKKLELNFDDKVWKIIRSRSIADERIILDKDYLVKKYVENITEEICEESI
YKYIEDELGLKIAYAKKEITVQFATEEDKKYLDMKNFNMIVVVKSYTYLDDTSLFQYTESRHRPDKFKFVDFARRRK
>Mature_236_residues
ASKYFNIYSEIANKIENGIFKANDEISSESDLMKEYKVSRDTARKALILLKENGYIQKIKGRRSFVLDINKFDFPVSGVV
SFKEIADKLGPNSKTKVEILECIHPNESMSKKLELNFDDKVWKIIRSRSIADERIILDKDYLVKKYVENITEEICEESIY
KYIEDELGLKIAYAKKEITVQFATEEDKKYLDMKNFNMIVVVKSYTYLDDTSLFQYTESRHRPDKFKFVDFARRRK

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=232, Percent_Identity=26.7241379310345, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790540, Length=233, Percent_Identity=21.0300429184549, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790118, Length=217, Percent_Identity=22.1198156682028, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27949; Mature: 27818

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKYFNIYSEIANKIENGIFKANDEISSESDLMKEYKVSRDTARKALILLKENGYIQKI
CCCHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCEEEE
KGRRSFVLDINKFDFPVSGVVSFKEIADKLGPNSKTKVEILECIHPNESMSKKLELNFDD
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHCCEEECCCCH
KVWKIIRSRSIADERIILDKDYLVKKYVENITEEICEESIYKYIEDELGLKIAYAKKEIT
HHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEE
VQFATEEDKKYLDMKNFNMIVVVKSYTYLDDTSLFQYTESRHRPDKFKFVDFARRRK
EEEECCCCHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
ASKYFNIYSEIANKIENGIFKANDEISSESDLMKEYKVSRDTARKALILLKENGYIQKI
CCHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCEEEE
KGRRSFVLDINKFDFPVSGVVSFKEIADKLGPNSKTKVEILECIHPNESMSKKLELNFDD
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHCCEEECCCCH
KVWKIIRSRSIADERIILDKDYLVKKYVENITEEICEESIYKYIEDELGLKIAYAKKEIT
HHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEE
VQFATEEDKKYLDMKNFNMIVVVKSYTYLDDTSLFQYTESRHRPDKFKFVDFARRRK
EEEECCCCHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]