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The map label for this gene is treC [H]

Identifier: 187934406

GI number: 187934406

Start: 1903781

End: 1905439

Strand: Reverse

Name: treC [H]

Synonym: CLL_A1820

Alternate gene names: 187934406

Gene position: 1905439-1903781 (Counterclockwise)

Preceding gene: 187935414

Following gene: 187933880

Centisome position: 50.14

GC content: 27.0

Gene sequence:

>1659_bases
ATGAAAGACTTTAAAAAAAGTACTGTTTATCAAATATATCCTAAATCATTTAATGATTCAAATGGAGATGGAATAGGCGA
TTTAAATGGAGTAATAGACAAACTAGATTATTTAGAGGAATTAGGGATTGATTATATTTGGCTTACTCCTTTTTATGTAT
CACCACAAAATGATAATGGCTATGATGTAGCTGATTATTATAATATAGATCCTTTGTTTGGAACTAATGAGGATTTTGAT
AGACTTGTTAAAGAAGCTGAAAAAAGAAATATTAATATAATGCTTGATATGGTATTTAATCATACTTCAACGGAGCATCA
ATGGTTTAAAAATGCCCTAAATGGAGATGAAAAATTCAAAGACTTTTATATATTTAGAAAAGGTAAAGACAGCAATCCAC
CAACTAATTGGAAATCAAAATTCGGAGGAAATGCTTGGGAATATATAGACACCTTTGATGAATACTATTTGCATCTATTT
GATAAAACACAAGGAGATTTAGACTGGACCAATTTAGATGTTAAAAATGAAATATATAAAATAGTAAACCATTGGATAAA
CAAAGGTGTTAAAGGATTTAGGTTTGATGTTATAAATCTAATTTCAAAGCCGGAAAAATTTGAAGATGATGTTATTGGTG
ATGGAAGAAGATTTTATACAGATGGACCTAATATACATAAATATTTAAAGGAATTAAATGAAAATACGTTTGGTAAGTAT
GACGATATAATAACAGTTGGAGAAATGTCTTCTACAACTATAGATAACTGTATTAAGTATTCAAATCCAAATGAAAAAGA
GCTATCTATGGTATTTAATTTCCATCATTTAAAAGTAGATTATGACAATGGTGATAAATGGACACTTATGAACTTTGATT
TTAAATTACTAAAATCTATCTTTAAAGAATGGCAGGAAGGTATGGAACAAGGAAATGGTTGGAATGCAGTATTTTGGTGT
AACCATGATCAGCCAAGAATAATTTCTAGATTTGGAAACACTGATAAGTATCATAAAGAAAGTGGAAAGATGCTTGGGAC
TTGTATTCACATGATGAGAGGAACACCATATATTTATCAGGGTGAAGAATTTGGAATGACAAATCCTAATTTTAATTCAA
TAGATGAATATAGAGATATTGAATCTAAGAATTATTATGATATTTTAAAAGAAAATCATGTTGAAGAGGAAGAAATATAT
AAGATATTAGCCTCAAAATCAAGAGATAATTCAAGAACACCTATGCAATGGAATGATGAAAAAAATAGTGGTTTTTCTAA
TAATGAGCCTTGGATACCAGTAGGTAAATCTTATAAAGAAATAAATGCTAAAAATGCATTAAAAGATAATGATTCTATAT
TCTATCATTATAAAAAACTTATAGATATTAGAAAAGAATATGATGTTGTTTCAAATGGGTCTTTCAATATGATACTTGAA
GAGCATGAAAAAGTTTTAGCATATACTAGAGAATATAATAATGAGAAATTAATAGTTTTAAATAACTTCTATGATGAAGA
GACTGAGGTATTATTACCACATGATCTTTTATGTGGTAATGGTAGAATATTAATTTCAAATTATAAAGATAGTATGGATT
TAAATGATAAAATTTTACTTAGACCATATGAATCTATTGTTTATATTGTTGAGAATTAA

Upstream 100 bases:

>100_bases
GGTTGCTGCTATAGTAGTACCATTTATGCTAACTTTAATAATTGGAAAGAAAAAATTAGTATAAAATAAATAATAATTTT
AAATTGGAGGACTTAGCAGT

Downstream 100 bases:

>100_bases
GTATATATTATGTTAAAATGTTTATGGTGATGAATGATGGCTAGCAAATATTTTAATATATATAGTGAAATTGCAAATAA
AATAGAAAATGGGATATTTA

Product: alpha,alpha-phosphotrehalase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MKDFKKSTVYQIYPKSFNDSNGDGIGDLNGVIDKLDYLEELGIDYIWLTPFYVSPQNDNGYDVADYYNIDPLFGTNEDFD
RLVKEAEKRNINIMLDMVFNHTSTEHQWFKNALNGDEKFKDFYIFRKGKDSNPPTNWKSKFGGNAWEYIDTFDEYYLHLF
DKTQGDLDWTNLDVKNEIYKIVNHWINKGVKGFRFDVINLISKPEKFEDDVIGDGRRFYTDGPNIHKYLKELNENTFGKY
DDIITVGEMSSTTIDNCIKYSNPNEKELSMVFNFHHLKVDYDNGDKWTLMNFDFKLLKSIFKEWQEGMEQGNGWNAVFWC
NHDQPRIISRFGNTDKYHKESGKMLGTCIHMMRGTPYIYQGEEFGMTNPNFNSIDEYRDIESKNYYDILKENHVEEEEIY
KILASKSRDNSRTPMQWNDEKNSGFSNNEPWIPVGKSYKEINAKNALKDNDSIFYHYKKLIDIRKEYDVVSNGSFNMILE
EHEKVLAYTREYNNEKLIVLNNFYDEETEVLLPHDLLCGNGRILISNYKDSMDLNDKILLRPYESIVYIVEN

Sequences:

>Translated_552_residues
MKDFKKSTVYQIYPKSFNDSNGDGIGDLNGVIDKLDYLEELGIDYIWLTPFYVSPQNDNGYDVADYYNIDPLFGTNEDFD
RLVKEAEKRNINIMLDMVFNHTSTEHQWFKNALNGDEKFKDFYIFRKGKDSNPPTNWKSKFGGNAWEYIDTFDEYYLHLF
DKTQGDLDWTNLDVKNEIYKIVNHWINKGVKGFRFDVINLISKPEKFEDDVIGDGRRFYTDGPNIHKYLKELNENTFGKY
DDIITVGEMSSTTIDNCIKYSNPNEKELSMVFNFHHLKVDYDNGDKWTLMNFDFKLLKSIFKEWQEGMEQGNGWNAVFWC
NHDQPRIISRFGNTDKYHKESGKMLGTCIHMMRGTPYIYQGEEFGMTNPNFNSIDEYRDIESKNYYDILKENHVEEEEIY
KILASKSRDNSRTPMQWNDEKNSGFSNNEPWIPVGKSYKEINAKNALKDNDSIFYHYKKLIDIRKEYDVVSNGSFNMILE
EHEKVLAYTREYNNEKLIVLNNFYDEETEVLLPHDLLCGNGRILISNYKDSMDLNDKILLRPYESIVYIVEN
>Mature_552_residues
MKDFKKSTVYQIYPKSFNDSNGDGIGDLNGVIDKLDYLEELGIDYIWLTPFYVSPQNDNGYDVADYYNIDPLFGTNEDFD
RLVKEAEKRNINIMLDMVFNHTSTEHQWFKNALNGDEKFKDFYIFRKGKDSNPPTNWKSKFGGNAWEYIDTFDEYYLHLF
DKTQGDLDWTNLDVKNEIYKIVNHWINKGVKGFRFDVINLISKPEKFEDDVIGDGRRFYTDGPNIHKYLKELNENTFGKY
DDIITVGEMSSTTIDNCIKYSNPNEKELSMVFNFHHLKVDYDNGDKWTLMNFDFKLLKSIFKEWQEGMEQGNGWNAVFWC
NHDQPRIISRFGNTDKYHKESGKMLGTCIHMMRGTPYIYQGEEFGMTNPNFNSIDEYRDIESKNYYDILKENHVEEEEIY
KILASKSRDNSRTPMQWNDEKNSGFSNNEPWIPVGKSYKEINAKNALKDNDSIFYHYKKLIDIRKEYDVVSNGSFNMILE
EHEKVLAYTREYNNEKLIVLNNFYDEETEVLLPHDLLCGNGRILISNYKDSMDLNDKILLRPYESIVYIVEN

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=564, Percent_Identity=28.5460992907801, Blast_Score=215, Evalue=1e-55,
Organism=Escherichia coli, GI1790687, Length=548, Percent_Identity=50.3649635036496, Blast_Score=599, Evalue=1e-172,
Organism=Escherichia coli, GI1786604, Length=188, Percent_Identity=29.2553191489362, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25147709, Length=497, Percent_Identity=24.3460764587525, Blast_Score=105, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI32565753, Length=199, Percent_Identity=27.6381909547739, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322245, Length=576, Percent_Identity=38.1944444444444, Blast_Score=375, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6321726, Length=578, Percent_Identity=37.7162629757785, Blast_Score=358, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6322241, Length=577, Percent_Identity=37.261698440208, Blast_Score=351, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6322021, Length=577, Percent_Identity=37.261698440208, Blast_Score=351, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6324416, Length=577, Percent_Identity=37.261698440208, Blast_Score=351, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6321731, Length=584, Percent_Identity=36.3013698630137, Blast_Score=345, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6319776, Length=584, Percent_Identity=36.1301369863014, Blast_Score=343, Evalue=4e-95,
Organism=Drosophila melanogaster, GI221330053, Length=498, Percent_Identity=35.5421686746988, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24586593, Length=589, Percent_Identity=32.088285229202, Blast_Score=271, Evalue=1e-72,
Organism=Drosophila melanogaster, GI45549022, Length=526, Percent_Identity=34.4106463878327, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24583749, Length=531, Percent_Identity=33.1450094161959, Blast_Score=258, Evalue=9e-69,
Organism=Drosophila melanogaster, GI24583747, Length=529, Percent_Identity=33.0812854442344, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24583745, Length=577, Percent_Identity=31.369150779896, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24586589, Length=581, Percent_Identity=33.0464716006885, Blast_Score=252, Evalue=5e-67,
Organism=Drosophila melanogaster, GI24586599, Length=529, Percent_Identity=30.812854442344, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24586597, Length=499, Percent_Identity=31.8637274549098, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24586591, Length=582, Percent_Identity=31.786941580756, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24586587, Length=591, Percent_Identity=28.087986463621, Blast_Score=232, Evalue=6e-61,
Organism=Drosophila melanogaster, GI281360393, Length=532, Percent_Identity=29.6992481203008, Blast_Score=199, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 65222; Mature: 65222

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFKKSTVYQIYPKSFNDSNGDGIGDLNGVIDKLDYLEELGIDYIWLTPFYVSPQNDNG
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCC
YDVADYYNIDPLFGTNEDFDRLVKEAEKRNINIMLDMVFNHTSTEHQWFKNALNGDEKFK
CCCHHEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCCHHHC
DFYIFRKGKDSNPPTNWKSKFGGNAWEYIDTFDEYYLHLFDKTQGDLDWTNLDVKNEIYK
EEEEEECCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
IVNHWINKGVKGFRFDVINLISKPEKFEDDVIGDGRRFYTDGPNIHKYLKELNENTFGKY
HHHHHHHCCCCCHHHHHHHHHCCCCHHCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCC
DDIITVGEMSSTTIDNCIKYSNPNEKELSMVFNFHHLKVDYDNGDKWTLMNFDFKLLKSI
CCEEEECCCCCHHHHHHHHCCCCCHHHEEEEEEEEEEEEEECCCCEEEEECCCHHHHHHH
FKEWQEGMEQGNGWNAVFWCNHDQPRIISRFGNTDKYHKESGKMLGTCIHMMRGTPYIYQ
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCCEEEE
GEEFGMTNPNFNSIDEYRDIESKNYYDILKENHVEEEEIYKILASKSRDNSRTPMQWNDE
CCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
KNSGFSNNEPWIPVGKSYKEINAKNALKDNDSIFYHYKKLIDIRKEYDVVSNGSFNMILE
CCCCCCCCCCCCCCCCCHHHHCHHHCCCCCCCEEHHHHHHHHHHHHHCEECCCCEEEHHH
EHEKVLAYTREYNNEKLIVLNNFYDEETEVLLPHDLLCGNGRILISNYKDSMDLNDKILL
HHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCEEECCCEEEEECCCCCCCCCCEEEE
RPYESIVYIVEN
EECCEEEEEEEC
>Mature Secondary Structure
MKDFKKSTVYQIYPKSFNDSNGDGIGDLNGVIDKLDYLEELGIDYIWLTPFYVSPQNDNG
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCC
YDVADYYNIDPLFGTNEDFDRLVKEAEKRNINIMLDMVFNHTSTEHQWFKNALNGDEKFK
CCCHHEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCCHHHC
DFYIFRKGKDSNPPTNWKSKFGGNAWEYIDTFDEYYLHLFDKTQGDLDWTNLDVKNEIYK
EEEEEECCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
IVNHWINKGVKGFRFDVINLISKPEKFEDDVIGDGRRFYTDGPNIHKYLKELNENTFGKY
HHHHHHHCCCCCHHHHHHHHHCCCCHHCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCC
DDIITVGEMSSTTIDNCIKYSNPNEKELSMVFNFHHLKVDYDNGDKWTLMNFDFKLLKSI
CCEEEECCCCCHHHHHHHHCCCCCHHHEEEEEEEEEEEEEECCCCEEEEECCCHHHHHHH
FKEWQEGMEQGNGWNAVFWCNHDQPRIISRFGNTDKYHKESGKMLGTCIHMMRGTPYIYQ
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCCEEEE
GEEFGMTNPNFNSIDEYRDIESKNYYDILKENHVEEEEIYKILASKSRDNSRTPMQWNDE
CCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
KNSGFSNNEPWIPVGKSYKEINAKNALKDNDSIFYHYKKLIDIRKEYDVVSNGSFNMILE
CCCCCCCCCCCCCCCCCHHHHCHHHCCCCCCCEEHHHHHHHHHHHHHCEECCCCEEEHHH
EHEKVLAYTREYNNEKLIVLNNFYDEETEVLLPHDLLCGNGRILISNYKDSMDLNDKILL
HHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCEEECCCEEEEECCCCCCCCCCEEEE
RPYESIVYIVEN
EECCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]