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The map label for this gene is lepB [H]

Identifier: 187933553

GI number: 187933553

Start: 3448484

End: 3449011

Strand: Reverse

Name: lepB [H]

Synonym: CLL_A3284

Alternate gene names: 187933553

Gene position: 3449011-3448484 (Counterclockwise)

Preceding gene: 187934098

Following gene: 187932527

Centisome position: 90.76

GC content: 29.55

Gene sequence:

>528_bases
ATGGAGAAAAGTAATAAGACAAAAAAAGAGAATTTTTTTACTGAATGGATAGTACCAATATTTGCAGCAGTAGTGATAGC
ATTTTTAGTGAATAAATTTTTAGTTTATAATGTATATATTCCAAGCGAATCAATGGTTCCAACATTAAATATAGGTGATA
AGTTATTCGTAACTAAAATTTATAATTTAGATAAGATAGAACATGAAGATATAGTTGTATTTTACTCAAATGAACTTCAA
GAAACAGTGATAAAAAGAGTTATAGGACTTCCTGGAGATCATATAGAGATAAGGGATGGAGTCGTAAGTGTAAATGGAGA
AGAACTAGTTGAAAATTATGTTAAAAATAATGAGGAATATGATGGAACTTTTGATGTTCCAGAAGGAAAATATTTCTTTT
TAGGGGATAATAGAGCAAGATCAAATGATGCTAGAAGATGGATTAATCCGTACATAGATGGAGATGATATAAAAGGAAAG
GCACAAGTTAAGGTTTGGCCTTTTAAAGACTTTGGGCGCTTGAATTAA

Upstream 100 bases:

>100_bases
ATATCCTATAAGTGACTTTAAAGTGTATAAATAATTGATAAATTGCTAATTAATTATAAAGGGACTCTAATTGTTTGTGT
CCTTAAAGGAGAATATGTTT

Downstream 100 bases:

>100_bases
TAGTACTTATTTTATAATAATATGGTATACTAGTTGTTAAGATATTTTATTTAGATTAGAGCTATATTTTAAGTTATATT
TTATATAAAAATGACTTAAA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MEKSNKTKKENFFTEWIVPIFAAVVIAFLVNKFLVYNVYIPSESMVPTLNIGDKLFVTKIYNLDKIEHEDIVVFYSNELQ
ETVIKRVIGLPGDHIEIRDGVVSVNGEELVENYVKNNEEYDGTFDVPEGKYFFLGDNRARSNDARRWINPYIDGDDIKGK
AQVKVWPFKDFGRLN

Sequences:

>Translated_175_residues
MEKSNKTKKENFFTEWIVPIFAAVVIAFLVNKFLVYNVYIPSESMVPTLNIGDKLFVTKIYNLDKIEHEDIVVFYSNELQ
ETVIKRVIGLPGDHIEIRDGVVSVNGEELVENYVKNNEEYDGTFDVPEGKYFFLGDNRARSNDARRWINPYIDGDDIKGK
AQVKVWPFKDFGRLN
>Mature_175_residues
MEKSNKTKKENFFTEWIVPIFAAVVIAFLVNKFLVYNVYIPSESMVPTLNIGDKLFVTKIYNLDKIEHEDIVVFYSNELQ
ETVIKRVIGLPGDHIEIRDGVVSVNGEELVENYVKNNEEYDGTFDVPEGKYFFLGDNRARSNDARRWINPYIDGDDIKGK
AQVKVWPFKDFGRLN

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 20276; Mature: 20276

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKSNKTKKENFFTEWIVPIFAAVVIAFLVNKFLVYNVYIPSESMVPTLNIGDKLFVTKI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEECCCCEEEEEEE
YNLDKIEHEDIVVFYSNELQETVIKRVIGLPGDHIEIRDGVVSVNGEELVENYVKNNEEY
CCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEECCEEEECHHHHHHHHHHCCCCC
DGTFDVPEGKYFFLGDNRARSNDARRWINPYIDGDDIKGKAQVKVWPFKDFGRLN
CCEEECCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MEKSNKTKKENFFTEWIVPIFAAVVIAFLVNKFLVYNVYIPSESMVPTLNIGDKLFVTKI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEECCCCEEEEEEE
YNLDKIEHEDIVVFYSNELQETVIKRVIGLPGDHIEIRDGVVSVNGEELVENYVKNNEEY
CCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEECCEEEECHHHHHHHHHHCCCCC
DGTFDVPEGKYFFLGDNRARSNDARRWINPYIDGDDIKGKAQVKVWPFKDFGRLN
CCEEECCCCCEEEEECCCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]