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The map label for this gene is lepB [H]

Identifier: 187934098

GI number: 187934098

Start: 3449078

End: 3449596

Strand: Reverse

Name: lepB [H]

Synonym: CLL_A3285

Alternate gene names: 187934098

Gene position: 3449596-3449078 (Counterclockwise)

Preceding gene: 187935097

Following gene: 187933553

Centisome position: 90.77

GC content: 28.32

Gene sequence:

>519_bases
ATGGAAGATAGCAGCAAAAATAGTTTTATAAAAGAATGGGGTTTAACCATTATAAGTGCCGTAGTAATAGGTTTATTATT
ATGGAAATTTTTAATTTATACTGTATGGATTACAAGTGGATCAATGATACCCACATTAGAGGTTAAAGATAGACTTGTTG
CAACAAGAGTTCATAATCCTGAAAATCTAAATAGAGGTGATATTGTTATATTTGATTCTGATGAGCTTAAAGAGATTCTT
ATAAAAAGACTTATAGGGCTTCCAGGAGATCATATAGAAATAAAAAATGGAATAGTGAGCGTAAATGGAGAACAATTAGT
AGAAGATTATGTTAAAAATAATGAGGACTATGATAGAATTTTTGATGTTCCACAAGGAGAATATTTCTTTTTAGGAGATA
ATAGAGCTAATTCAGATGATTCTAGATATTGGAAGAATCCGTATATAAAAAGCGAAAAAATACAAGGAAAAGCTAAAGTG
AAAATATATCCTATAAGTGACTTTAAAGTGTATAAATAA

Upstream 100 bases:

>100_bases
AATAATTATAAAAGTACATAGTATAATTATAAAATTAATGTCGTTAGTTATTATATTTAAAAAAGTATAGTATATGGAAT
TTCAGAAAGGTGGAATTTAT

Downstream 100 bases:

>100_bases
TTGATAAATTGCTAATTAATTATAAAGGGACTCTAATTGTTTGTGTCCTTAAAGGAGAATATGTTTATGGAGAAAAGTAA
TAAGACAAAAAAAGAGAATT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I-2; Leader peptidase I-2 [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MEDSSKNSFIKEWGLTIISAVVIGLLLWKFLIYTVWITSGSMIPTLEVKDRLVATRVHNPENLNRGDIVIFDSDELKEIL
IKRLIGLPGDHIEIKNGIVSVNGEQLVEDYVKNNEDYDRIFDVPQGEYFFLGDNRANSDDSRYWKNPYIKSEKIQGKAKV
KIYPISDFKVYK

Sequences:

>Translated_172_residues
MEDSSKNSFIKEWGLTIISAVVIGLLLWKFLIYTVWITSGSMIPTLEVKDRLVATRVHNPENLNRGDIVIFDSDELKEIL
IKRLIGLPGDHIEIKNGIVSVNGEQLVEDYVKNNEDYDRIFDVPQGEYFFLGDNRANSDDSRYWKNPYIKSEKIQGKAKV
KIYPISDFKVYK
>Mature_172_residues
MEDSSKNSFIKEWGLTIISAVVIGLLLWKFLIYTVWITSGSMIPTLEVKDRLVATRVHNPENLNRGDIVIFDSDELKEIL
IKRLIGLPGDHIEIKNGIVSVNGEQLVEDYVKNNEDYDRIFDVPQGEYFFLGDNRANSDDSRYWKNPYIKSEKIQGKAKV
KIYPISDFKVYK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 19860; Mature: 19860

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDSSKNSFIKEWGLTIISAVVIGLLLWKFLIYTVWITSGSMIPTLEVKDRLVATRVHNP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCC
ENLNRGDIVIFDSDELKEILIKRLIGLPGDHIEIKNGIVSVNGEQLVEDYVKNNEDYDRI
CCCCCCCEEEECCHHHHHHHHHHHHCCCCCEEEECCCEEEECHHHHHHHHHHCCCCCHHH
FDVPQGEYFFLGDNRANSDDSRYWKNPYIKSEKIQGKAKVKIYPISDFKVYK
CCCCCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCCCEEEEEEECCCEEECC
>Mature Secondary Structure
MEDSSKNSFIKEWGLTIISAVVIGLLLWKFLIYTVWITSGSMIPTLEVKDRLVATRVHNP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCC
ENLNRGDIVIFDSDELKEILIKRLIGLPGDHIEIKNGIVSVNGEQLVEDYVKNNEDYDRI
CCCCCCCEEEECCHHHHHHHHHHHHCCCCCEEEECCCEEEECHHHHHHHHHHCCCCCHHH
FDVPQGEYFFLGDNRANSDDSRYWKNPYIKSEKIQGKAKVKIYPISDFKVYK
CCCCCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCCCEEEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]