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The map label for this gene is yycG [H]

Identifier: 187933272

GI number: 187933272

Start: 2795012

End: 2796310

Strand: Reverse

Name: yycG [H]

Synonym: CLL_A2680

Alternate gene names: 187933272

Gene position: 2796310-2795012 (Counterclockwise)

Preceding gene: 187933165

Following gene: 187935125

Centisome position: 73.58

GC content: 24.1

Gene sequence:

>1299_bases
ATGATTGACTTTAAAAAAGTTAGAATAAATTTAATCTGGGGAATTATTATTGGATTTTTTTTATCTCAAGTTATTGTTGC
AGAAGGGTATGCAATATTAGTGTTTAGACAACAAAATGGTAGTGGAGATGTTGCCTTACCATTTGAAGGAATTACTGGAT
TTAGAATTTTAGCTTTTATTGTGTTTATAGCTACTATAGCAATATTTAACACGAAAAAATTCAGAAAAATTAATTTAAAT
AAGATTAGTATTTACTTAATATTAGTAGTTATAATAGCAGTTGTAGTAGCTATTGAGGCTGTACTAATTATAATTTCAAT
TATTTTTAAGAGGCATCCTAATATACAAGAATATGTTGCAAAAGATTATTTTGTATCAGTAAATATATTTTATATTATCA
GTTTTTTAGGTATTGCTGTATTTTTAATAACATTTGTAAGCCTTGTAAATAGGAAAGTAAAATACATTAAGTTTTTAACT
AAGGAAGTAAAGGTTATTAAAGATGAAGGCTTTGGAAAAACTATTAAAGTTAAAGGGAAAGATGAATTATCAGAGCTTTG
CCAAAGCATAAATGATATGTCATTAGAATTGCGTAAAAAAATAGATAATGAAAAAATTATTGAAAAAAATAAAAATGAAC
TTATAACAAGTGTATCTCATGACTTAAGAACACCACTTACATCTATCATAGGATATGTAGATTTGCTTAAGAAAAATGAA
TTTAATGATAAAGAAAAGTTTGATAACTATATAGAGGTTATAGATGAAAGAACTAAAAGCCTTAATAGATTAATCAATGA
ACTTTTTGAATATACAAAACTAACTAGTCATGATATTAAATTAAATTATAGTAGATTAGAAATAGTATCATTAATAGAAC
AAATGGTTGGGGAATATACTCCTATATTTAATAAGGAGAACTTAGAAGTAATAAAAGATATAACTGATAAAGATATATTT
ATTAATGCTGATATAGAGAAGATTGTAAGGGTTTTAGAAAATCTTTTAACTAATGCTATAAAATATAGTGTAAAAAACTC
TAAAGTATTAATAAAGCTGTTTGAAGAAAATAATTATGTGGTAGTTTCTGTATCAAACAAAGCTAAAGACATTACAGAAG
ATGATTTGAAAAATATATTTGAGAGATTTTATAAAGTTGATAAATCAAGAAAAGAACAAGATAGTACAGGACTTGGACTA
TCTATTGTTAAAAGAATAGTTGAACTTCATAATGGAGAGATAGATGTTAATTTAAATGAAGACATTATAGAATTTAAAAT
ATCATTACCCTTAGAGTAA

Upstream 100 bases:

>100_bases
ATACTGTTACAGTTCATATAACGAATTTAAGAGAAAAAATTGAAGCTGATCCTAAAGCTCCTGTATATATAAAAACAATA
TGGGGAGTAGGTTATAAGAT

Downstream 100 bases:

>100_bases
AAGAAATACCTATAGAATTTTTGAAGCTAAATTCTATAGGTATTTTTATATTCTAATTACTATGCACATTTAGTGATTTT
ATTCATTTAAATCTTTTATT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MIDFKKVRINLIWGIIIGFFLSQVIVAEGYAILVFRQQNGSGDVALPFEGITGFRILAFIVFIATIAIFNTKKFRKINLN
KISIYLILVVIIAVVVAIEAVLIIISIIFKRHPNIQEYVAKDYFVSVNIFYIISFLGIAVFLITFVSLVNRKVKYIKFLT
KEVKVIKDEGFGKTIKVKGKDELSELCQSINDMSLELRKKIDNEKIIEKNKNELITSVSHDLRTPLTSIIGYVDLLKKNE
FNDKEKFDNYIEVIDERTKSLNRLINELFEYTKLTSHDIKLNYSRLEIVSLIEQMVGEYTPIFNKENLEVIKDITDKDIF
INADIEKIVRVLENLLTNAIKYSVKNSKVLIKLFEENNYVVVSVSNKAKDITEDDLKNIFERFYKVDKSRKEQDSTGLGL
SIVKRIVELHNGEIDVNLNEDIIEFKISLPLE

Sequences:

>Translated_432_residues
MIDFKKVRINLIWGIIIGFFLSQVIVAEGYAILVFRQQNGSGDVALPFEGITGFRILAFIVFIATIAIFNTKKFRKINLN
KISIYLILVVIIAVVVAIEAVLIIISIIFKRHPNIQEYVAKDYFVSVNIFYIISFLGIAVFLITFVSLVNRKVKYIKFLT
KEVKVIKDEGFGKTIKVKGKDELSELCQSINDMSLELRKKIDNEKIIEKNKNELITSVSHDLRTPLTSIIGYVDLLKKNE
FNDKEKFDNYIEVIDERTKSLNRLINELFEYTKLTSHDIKLNYSRLEIVSLIEQMVGEYTPIFNKENLEVIKDITDKDIF
INADIEKIVRVLENLLTNAIKYSVKNSKVLIKLFEENNYVVVSVSNKAKDITEDDLKNIFERFYKVDKSRKEQDSTGLGL
SIVKRIVELHNGEIDVNLNEDIIEFKISLPLE
>Mature_432_residues
MIDFKKVRINLIWGIIIGFFLSQVIVAEGYAILVFRQQNGSGDVALPFEGITGFRILAFIVFIATIAIFNTKKFRKINLN
KISIYLILVVIIAVVVAIEAVLIIISIIFKRHPNIQEYVAKDYFVSVNIFYIISFLGIAVFLITFVSLVNRKVKYIKFLT
KEVKVIKDEGFGKTIKVKGKDELSELCQSINDMSLELRKKIDNEKIIEKNKNELITSVSHDLRTPLTSIIGYVDLLKKNE
FNDKEKFDNYIEVIDERTKSLNRLINELFEYTKLTSHDIKLNYSRLEIVSLIEQMVGEYTPIFNKENLEVIKDITDKDIF
INADIEKIVRVLENLLTNAIKYSVKNSKVLIKLFEENNYVVVSVSNKAKDITEDDLKNIFERFYKVDKSRKEQDSTGLGL
SIVKRIVELHNGEIDVNLNEDIIEFKISLPLE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=265, Percent_Identity=24.1509433962264, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=23.5521235521236, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=28.2157676348548, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87082128, Length=340, Percent_Identity=22.9411764705882, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788713, Length=265, Percent_Identity=22.6415094339623, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790551, Length=288, Percent_Identity=23.2638888888889, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786600, Length=211, Percent_Identity=21.8009478672986, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786783, Length=250, Percent_Identity=24.4, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1789808, Length=243, Percent_Identity=25.1028806584362, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788549, Length=206, Percent_Identity=26.6990291262136, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=27.6018099547511, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=283, Percent_Identity=23.6749116607774, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790346, Length=247, Percent_Identity=25.5060728744939, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=312, Percent_Identity=25, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788279, Length=298, Percent_Identity=25.8389261744966, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=26.4957264957265, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=246, Percent_Identity=22.3577235772358, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48994928, Length=223, Percent_Identity=22.8699551569507, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789403, Length=320, Percent_Identity=22.1875, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49825; Mature: 49825

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFKKVRINLIWGIIIGFFLSQVIVAEGYAILVFRQQNGSGDVALPFEGITGFRILAFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHH
VFIATIAIFNTKKFRKINLNKISIYLILVVIIAVVVAIEAVLIIISIIFKRHPNIQEYVA
HHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KDYFVSVNIFYIISFLGIAVFLITFVSLVNRKVKYIKFLTKEVKVIKDEGFGKTIKVKGK
HHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCH
DELSELCQSINDMSLELRKKIDNEKIIEKNKNELITSVSHDLRTPLTSIIGYVDLLKKNE
HHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FNDKEKFDNYIEVIDERTKSLNRLINELFEYTKLTSHDIKLNYSRLEIVSLIEQMVGEYT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCC
PIFNKENLEVIKDITDKDIFINADIEKIVRVLENLLTNAIKYSVKNSKVLIKLFEENNYV
CCCCCCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEE
VVSVSNKAKDITEDDLKNIFERFYKVDKSRKEQDSTGLGLSIVKRIVELHNGEIDVNLNE
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCC
DIIEFKISLPLE
CEEEEEEECCCC
>Mature Secondary Structure
MIDFKKVRINLIWGIIIGFFLSQVIVAEGYAILVFRQQNGSGDVALPFEGITGFRILAFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHH
VFIATIAIFNTKKFRKINLNKISIYLILVVIIAVVVAIEAVLIIISIIFKRHPNIQEYVA
HHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KDYFVSVNIFYIISFLGIAVFLITFVSLVNRKVKYIKFLTKEVKVIKDEGFGKTIKVKGK
HHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCH
DELSELCQSINDMSLELRKKIDNEKIIEKNKNELITSVSHDLRTPLTSIIGYVDLLKKNE
HHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FNDKEKFDNYIEVIDERTKSLNRLINELFEYTKLTSHDIKLNYSRLEIVSLIEQMVGEYT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCC
PIFNKENLEVIKDITDKDIFINADIEKIVRVLENLLTNAIKYSVKNSKVLIKLFEENNYV
CCCCCCCHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEE
VVSVSNKAKDITEDDLKNIFERFYKVDKSRKEQDSTGLGLSIVKRIVELHNGEIDVNLNE
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCC
DIIEFKISLPLE
CEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]