Click here to switch to the map view.

The map label for this gene is bsaA [H]

Identifier: 187918385

GI number: 187918385

Start: 537850

End: 538332

Strand: Direct

Name: bsaA [H]

Synonym: BH0519A

Alternate gene names: 187918385

Gene position: 537850-538332 (Clockwise)

Preceding gene: 187918380

Following gene: 187918386

Centisome position: 58.32

GC content: 32.3

Gene sequence:

>483_bases
ATGAGTGTGTATGGTTTTAGAGCAAGGCTTGCATCAGGGCCTGAAATTTCTCTTTCAGATTATATTCGAAAAGTATTGCT
TATAGTTAATGTGGCAAGTGATTGTAGTTATACAAATCAATATCAGGATTTGGAAGTGCTTTACAAGATATATAAACGGC
GGGGGTTTTTAATATTGGGATTTCCTTGTAATCAGTTTGGATTTCAGGAGCCTGGATCAAATAATGAGATTTTAAAATTT
TGTCGGACAGTTTATAATGTCTCATTTCCTATTTTTTCTAAAATTGATGTTAATGGTGAGAATGCACATCCTTTATATAG
ATATCTAAGAGAAAAATCTCCAGAGGAATTTAAAGGAGATATTCGTTGGAATTTTACTAAATTTTTAATAAACCGAGAAG
GCAATGTGGTAGGTAGGTATACTCCTAAGATAGCCCCAATTAAAATGAAAGATGATATTGAGAAATGGTTAAGTGTGATT
TAG

Upstream 100 bases:

>100_bases
TTATGTGTACTTTTTTGTCAAAATAAAAAAAATACATTGGTTGTTTTTGTTATTTAAAATTATGTCTAAAAATTGGCTTG
AATATATTTAAGGGGTTTTT

Downstream 100 bases:

>100_bases
AGTTTTCTTGTAATTTTTTCTGTTATTGCTTATTATTTATTTTGTGAAAATATGTATAGCGCAGACAAAATGTAGACTTT
TTAAGTTTAAACAGATTCTG

Product: glutathione peroxidase-like BsaA

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSVYGFRARLASGPEISLSDYIRKVLLIVNVASDCSYTNQYQDLEVLYKIYKRRGFLILGFPCNQFGFQEPGSNNEILKF
CRTVYNVSFPIFSKIDVNGENAHPLYRYLREKSPEEFKGDIRWNFTKFLINREGNVVGRYTPKIAPIKMKDDIEKWLSVI

Sequences:

>Translated_160_residues
MSVYGFRARLASGPEISLSDYIRKVLLIVNVASDCSYTNQYQDLEVLYKIYKRRGFLILGFPCNQFGFQEPGSNNEILKF
CRTVYNVSFPIFSKIDVNGENAHPLYRYLREKSPEEFKGDIRWNFTKFLINREGNVVGRYTPKIAPIKMKDDIEKWLSVI
>Mature_159_residues
SVYGFRARLASGPEISLSDYIRKVLLIVNVASDCSYTNQYQDLEVLYKIYKRRGFLILGFPCNQFGFQEPGSNNEILKFC
RTVYNVSFPIFSKIDVNGENAHPLYRYLREKSPEEFKGDIRWNFTKFLINREGNVVGRYTPKIAPIKMKDDIEKWLSVI

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=151, Percent_Identity=44.3708609271523, Blast_Score=126, Evalue=7e-30,
Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=43.8709677419355, Blast_Score=120, Evalue=5e-28,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=43.8709677419355, Blast_Score=120, Evalue=8e-28,
Organism=Homo sapiens, GI192455698, Length=143, Percent_Identity=44.0559440559441, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI41406084, Length=183, Percent_Identity=38.7978142076503, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI4557629, Length=177, Percent_Identity=37.2881355932203, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=44.6153846153846, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI6006001, Length=177, Percent_Identity=36.7231638418079, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI32967607, Length=183, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI33186887, Length=177, Percent_Identity=35.0282485875706, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1788003, Length=154, Percent_Identity=46.1038961038961, Blast_Score=142, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17535473, Length=159, Percent_Identity=44.0251572327044, Blast_Score=142, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=40.5063291139241, Blast_Score=141, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17506887, Length=158, Percent_Identity=43.0379746835443, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=39.5061728395062, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=36.8098159509202, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17550320, Length=163, Percent_Identity=36.8098159509202, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=38.9473684210526, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71999642, Length=77, Percent_Identity=45.4545454545455, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193210709, Length=74, Percent_Identity=47.2972972972973, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=159, Percent_Identity=47.7987421383648, Blast_Score=152, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6322228, Length=138, Percent_Identity=52.1739130434783, Blast_Score=149, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6322826, Length=156, Percent_Identity=41.6666666666667, Blast_Score=124, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=44.6540880503145, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=44.6540880503145, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24656767, Length=159, Percent_Identity=44.6540880503145, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI85726443, Length=160, Percent_Identity=40, Blast_Score=116, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 18682; Mature: 18551

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYGFRARLASGPEISLSDYIRKVLLIVNVASDCSYTNQYQDLEVLYKIYKRRGFLILG
CCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
FPCNQFGFQEPGSNNEILKFCRTVYNVSFPIFSKIDVNGENAHPLYRYLREKSPEEFKGD
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHCCC
IRWNFTKFLINREGNVVGRYTPKIAPIKMKDDIEKWLSVI
CEEEHEEEEECCCCCEEEEECCCEECEECHHHHHHHHHCC
>Mature Secondary Structure 
SVYGFRARLASGPEISLSDYIRKVLLIVNVASDCSYTNQYQDLEVLYKIYKRRGFLILG
CCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
FPCNQFGFQEPGSNNEILKFCRTVYNVSFPIFSKIDVNGENAHPLYRYLREKSPEEFKGD
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHCCC
IRWNFTKFLINREGNVVGRYTPKIAPIKMKDDIEKWLSVI
CEEEHEEEEECCCCCEEEEECCCEECEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10086841; 11058132 [H]