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The map label for this gene is trxB [H]

Identifier: 187918380

GI number: 187918380

Start: 532247

End: 533224

Strand: Direct

Name: trxB [H]

Synonym: BH0515

Alternate gene names: 187918380

Gene position: 532247-533224 (Clockwise)

Preceding gene: 187918379

Following gene: 187918385

Centisome position: 57.71

GC content: 34.25

Gene sequence:

>978_bases
ATGTTAAAGTTTGAAACACTGGATATAAAAAAGAGCAATAAAAGAATTGTAAGAACAGAGATGGGCTCTGTTGAAGATGT
GGTTATTGTTGGTTCAGGGCCCGCGGGGCTTACGGCTGGAATTTATACTGTTATGAGTGGATATAAGACAGTTGTCTTAG
AGGGCCCTGAGCCTGGGGGACAGCTTACAACGACTACGGAAGTGTATAATTATCCAGGATTTAAAAATGGTGTGAATGGA
AGAGAATTGATGTTAAATATGAAAGAACAGGTGATCAATCTGGGTGCTACCACGTATCTTGAAACTGTAAGATTCATAGA
AAAGAGAGATAATATTTTTTATATCTTTACTGATAATTATATTTATAAAAGCAGAGCTGTTATTATTGCAGCGGGCTCGG
TACCTAAAAAACTTGATACTCTTAAGAATTCAGATTTGTTTTGGAATAAAGGTATTTCTGTGTGTGCAATTTGTGATGGG
CATCTTTTTAAGGGTAAAACTGCTGCAGTAATTGGTGGGGGCAATACAGCAATCTCAGAAGCTATTTATTTAAGCAAATT
ATTAAAAAATGTATATGTTATTGTAAGAAGAGATTGTTTGAAAGCTATTGCTATGCTAAGAAGAGATGTTGAAAAGTTAC
CTAATGTTGAGATTTTATATAACTGTGAGGCTATAGAAGTTAATGGAGATAATGTTGTATCTGGTATGCAAATTATGAAT
AGTAAGGATAATTCTACTTTTAAGTTAAGTGTAGATGGAATATTTATAGCTATTGGTTATAAGCCAAATACGGATTTTTT
AAAAGGGTTTTTGGAATTAGATGAAGATGGATATATATCTACTCAAGCTCTTGTTAAGACTAGTGTTAAGGGAGTATTTT
CGTGTGGTGATGTTAGTAACAAGCTTTATGCACAAGCTATTACGGCTGCTGCTGAAGGGTTCCTAGCTTCTGTTGAAGTG
AGAAATTTTTTGGGATAA

Upstream 100 bases:

>100_bases
AGAAATGCATAAAATTTTTTATTTGTGGCATTTGAATGAAGTTATATTTAAATATTTGATGTAGTGCATTTTATAGGTTA
AATGGAGTTAATGGATATTT

Downstream 100 bases:

>100_bases
TTGGTTGGCTTAATTATAAAAAATGTGTTAAAGCAAATTAAGTTGTCTTTTTATTTCAAATATTAAAATTCCTGTTGAAA
CTGATACATTCAATGAATCT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLKFETLDIKKSNKRIVRTEMGSVEDVVIVGSGPAGLTAGIYTVMSGYKTVVLEGPEPGGQLTTTTEVYNYPGFKNGVNG
RELMLNMKEQVINLGATTYLETVRFIEKRDNIFYIFTDNYIYKSRAVIIAAGSVPKKLDTLKNSDLFWNKGISVCAICDG
HLFKGKTAAVIGGGNTAISEAIYLSKLLKNVYVIVRRDCLKAIAMLRRDVEKLPNVEILYNCEAIEVNGDNVVSGMQIMN
SKDNSTFKLSVDGIFIAIGYKPNTDFLKGFLELDEDGYISTQALVKTSVKGVFSCGDVSNKLYAQAITAAAEGFLASVEV
RNFLG

Sequences:

>Translated_325_residues
MLKFETLDIKKSNKRIVRTEMGSVEDVVIVGSGPAGLTAGIYTVMSGYKTVVLEGPEPGGQLTTTTEVYNYPGFKNGVNG
RELMLNMKEQVINLGATTYLETVRFIEKRDNIFYIFTDNYIYKSRAVIIAAGSVPKKLDTLKNSDLFWNKGISVCAICDG
HLFKGKTAAVIGGGNTAISEAIYLSKLLKNVYVIVRRDCLKAIAMLRRDVEKLPNVEILYNCEAIEVNGDNVVSGMQIMN
SKDNSTFKLSVDGIFIAIGYKPNTDFLKGFLELDEDGYISTQALVKTSVKGVFSCGDVSNKLYAQAITAAAEGFLASVEV
RNFLG
>Mature_325_residues
MLKFETLDIKKSNKRIVRTEMGSVEDVVIVGSGPAGLTAGIYTVMSGYKTVVLEGPEPGGQLTTTTEVYNYPGFKNGVNG
RELMLNMKEQVINLGATTYLETVRFIEKRDNIFYIFTDNYIYKSRAVIIAAGSVPKKLDTLKNSDLFWNKGISVCAICDG
HLFKGKTAAVIGGGNTAISEAIYLSKLLKNVYVIVRRDCLKAIAMLRRDVEKLPNVEILYNCEAIEVNGDNVVSGMQIMN
SKDNSTFKLSVDGIFIAIGYKPNTDFLKGFLELDEDGYISTQALVKTSVKGVFSCGDVSNKLYAQAITAAAEGFLASVEV
RNFLG

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=308, Percent_Identity=38.3116883116883, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI87081763, Length=304, Percent_Identity=32.8947368421053, Blast_Score=134, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6320560, Length=311, Percent_Identity=40.1929260450161, Blast_Score=225, Evalue=6e-60,
Organism=Saccharomyces cerevisiae, GI6321898, Length=311, Percent_Identity=38.9067524115756, Blast_Score=222, Evalue=6e-59,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35551; Mature: 35551

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFETLDIKKSNKRIVRTEMGSVEDVVIVGSGPAGLTAGIYTVMSGYKTVVLEGPEPGG
CCEEEEEECCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCC
QLTTTTEVYNYPGFKNGVNGRELMLNMKEQVINLGATTYLETVRFIEKRDNIFYIFTDNY
CEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCE
IYKSRAVIIAAGSVPKKLDTLKNSDLFWNKGISVCAICDGHLFKGKTAAVIGGGNTAISE
EEECCEEEEEECCCCHHHHHCCCCCEEECCCCEEEEEECCCEECCCEEEEEECCCHHHHH
AIYLSKLLKNVYVIVRRDCLKAIAMLRRDVEKLPNVEILYNCEAIEVNGDNVVSGMQIMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCHHHCC
SKDNSTFKLSVDGIFIAIGYKPNTDFLKGFLELDEDGYISTQALVKTSVKGVFSCGDVSN
CCCCCEEEEEECEEEEEEECCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHEEECCCCCH
KLYAQAITAAAEGFLASVEVRNFLG
HHHHHHHHHHHHHHHEEEEHHHHCC
>Mature Secondary Structure
MLKFETLDIKKSNKRIVRTEMGSVEDVVIVGSGPAGLTAGIYTVMSGYKTVVLEGPEPGG
CCEEEEEECCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCC
QLTTTTEVYNYPGFKNGVNGRELMLNMKEQVINLGATTYLETVRFIEKRDNIFYIFTDNY
CEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCE
IYKSRAVIIAAGSVPKKLDTLKNSDLFWNKGISVCAICDGHLFKGKTAAVIGGGNTAISE
EEECCEEEEEECCCCHHHHHCCCCCEEECCCCEEEEEECCCEECCCEEEEEECCCHHHHH
AIYLSKLLKNVYVIVRRDCLKAIAMLRRDVEKLPNVEILYNCEAIEVNGDNVVSGMQIMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCHHHCC
SKDNSTFKLSVDGIFIAIGYKPNTDFLKGFLELDEDGYISTQALVKTSVKGVFSCGDVSN
CCCCCEEEEEECEEEEEEECCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHEEECCCCCH
KLYAQAITAAAEGFLASVEVRNFLG
HHHHHHHHHHHHHHHEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]