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The map label for this gene is nahA [H]

Identifier: 187736498

GI number: 187736498

Start: 2452124

End: 2453638

Strand: Direct

Name: nahA [H]

Synonym: Amuc_2019

Alternate gene names: 187736498

Gene position: 2452124-2453638 (Clockwise)

Preceding gene: 187736497

Following gene: 187736499

Centisome position: 92.04

GC content: 56.04

Gene sequence:

>1515_bases
ATGGTAGAATCTTTTCCGAAACAGTTCTTCATGATGTTTAAACTGCCCCTCATCCTGGCCTGCGCCATTTTTTCCGCCCA
CATGGCATGTGCCGCCGCAGCGGACAAATACAGCGTTATCCCTGAACCGGAAAAAACGGAGCTGCAGCACAACAGTACCA
GAACCTTAAAACTTCTTTCCGACCAGGAGGCTCCGACCCTGGGAACGGACGCCTACCGGCTCACAGTCACCCCGCAGGGG
GCGCACCTTGCTTCCGGAGGAAGGGAAGGCAGAATTTACGGGCTGGCAACCCTCCGCCAGCTCCGGGACCAGCTGGCGGG
ACAGCCGGAGGGCATCCCCTGCGGCGTCATCACGGACAAGCCGCGCTATCCGTGGCGCGGCCTCATGGTAGATCCCGCAC
GCTTTTTCATCCCCACGGCCGATCTGAAAAAATTTGTGGATATGATGGCCTACTACAAATTCAACAAGCTCCAGATCCAC
TTGACGGACGACCAGGGGTGGCGTCTTCCGGTGCCCGGCTACCCCAAACTCAAAAGCATCTCCTCCAAACGGAAAGAAAG
CATGCGCAACGGAATCCCCCATGAAGGGATGTACACCAAACAGGAACTGAAAGAGCTGGTGGCGTACTGCGCAGCGCGCG
GCATTGAGGTCATCCCTGAAATAGACGTGCCGGGGCACAACCAAGCCCTGGCGGCAGCCTACCCTGAATTCTTCTGCTTC
CCGAACCCGGATACGAAAGTGAAGACCGATGAAGGCGTCACCCTCCACCTCATCTGCCCGCATAAACCGGAAGTCTGGAA
ATTTTATGCCGCTGTTTTCAAGGAACTCAAAGATATTTTCCCGTCCGGCATCGTCCATCTGGGCGGCGATGAAGCACCCC
TGGAAAAAACCTGGGCCAAATGCCCCCTCAGCATCCAGTACCGGGAGCAAAAAGGCATGAAGGACGTCCACGAGGAATTG
AAGGAATTCATCAAAAAAATGTCCTCCATGCTGGCTGTTCACGGCAAGCGCATCCAACTATGGTATGAAAAACCGTGGGC
CAGGGCCAACATCTACAACAAAGGAGACACCGTCTTCACCTGGCGCATGGGACTGACACCGTCCACCATCACGGAGACGA
AAAAGCAGGGGCTCTCCCTGATCATTGCTGCCGGGGAATACTGTTACCTGGACTATCCGCAACTTCCAGGGCAAAGCAAC
CGGGGATGGATGCCCACCACCACGCTGGAGCAAAGCTACAGGCTGGACCCCGCCTACGGCAGACCAGAAAAGGAAACAAA
CCATATCACCGGCGTTCAGGGCACCGTGTGGGGAGAACATCTCCCTACCCTGAACCACATTCTCTACCGCGCCTATCCGC
GTGCCTGCGCCATTGCGGAAGCCGGCTGGTCACCGATGAACGTGCGCTCCTGGGAAAACTTCCGGCGCAAGCTGGCCGAC
CACCGTCAATTCATCCTCAAACGCTTCAATTATGATATGGAGCGCACCAAAGAAAACGAACCGCCTTTCAAATAA

Upstream 100 bases:

>100_bases
TTCAATTATGATATGGAGCGCACTCAGGGGAATGAACCGGCCTTCCGCTGGGAAAACAACAAGTAATTTCACCGTTTTTC
CTTATCACGCATCCCTTACC

Downstream 100 bases:

>100_bases
TCCGCACTCTCTTTTCCCATGAGCAACATCAAATTTGCACGTCCGCACCGCCCTTCCGTAGAAGAACTGGCCCAGGGAGT
ACTGGCCGGAAACCGCGCCC

Product: Beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MVESFPKQFFMMFKLPLILACAIFSAHMACAAAADKYSVIPEPEKTELQHNSTRTLKLLSDQEAPTLGTDAYRLTVTPQG
AHLASGGREGRIYGLATLRQLRDQLAGQPEGIPCGVITDKPRYPWRGLMVDPARFFIPTADLKKFVDMMAYYKFNKLQIH
LTDDQGWRLPVPGYPKLKSISSKRKESMRNGIPHEGMYTKQELKELVAYCAARGIEVIPEIDVPGHNQALAAAYPEFFCF
PNPDTKVKTDEGVTLHLICPHKPEVWKFYAAVFKELKDIFPSGIVHLGGDEAPLEKTWAKCPLSIQYREQKGMKDVHEEL
KEFIKKMSSMLAVHGKRIQLWYEKPWARANIYNKGDTVFTWRMGLTPSTITETKKQGLSLIIAAGEYCYLDYPQLPGQSN
RGWMPTTTLEQSYRLDPAYGRPEKETNHITGVQGTVWGEHLPTLNHILYRAYPRACAIAEAGWSPMNVRSWENFRRKLAD
HRQFILKRFNYDMERTKENEPPFK

Sequences:

>Translated_504_residues
MVESFPKQFFMMFKLPLILACAIFSAHMACAAAADKYSVIPEPEKTELQHNSTRTLKLLSDQEAPTLGTDAYRLTVTPQG
AHLASGGREGRIYGLATLRQLRDQLAGQPEGIPCGVITDKPRYPWRGLMVDPARFFIPTADLKKFVDMMAYYKFNKLQIH
LTDDQGWRLPVPGYPKLKSISSKRKESMRNGIPHEGMYTKQELKELVAYCAARGIEVIPEIDVPGHNQALAAAYPEFFCF
PNPDTKVKTDEGVTLHLICPHKPEVWKFYAAVFKELKDIFPSGIVHLGGDEAPLEKTWAKCPLSIQYREQKGMKDVHEEL
KEFIKKMSSMLAVHGKRIQLWYEKPWARANIYNKGDTVFTWRMGLTPSTITETKKQGLSLIIAAGEYCYLDYPQLPGQSN
RGWMPTTTLEQSYRLDPAYGRPEKETNHITGVQGTVWGEHLPTLNHILYRAYPRACAIAEAGWSPMNVRSWENFRRKLAD
HRQFILKRFNYDMERTKENEPPFK
>Mature_504_residues
MVESFPKQFFMMFKLPLILACAIFSAHMACAAAADKYSVIPEPEKTELQHNSTRTLKLLSDQEAPTLGTDAYRLTVTPQG
AHLASGGREGRIYGLATLRQLRDQLAGQPEGIPCGVITDKPRYPWRGLMVDPARFFIPTADLKKFVDMMAYYKFNKLQIH
LTDDQGWRLPVPGYPKLKSISSKRKESMRNGIPHEGMYTKQELKELVAYCAARGIEVIPEIDVPGHNQALAAAYPEFFCF
PNPDTKVKTDEGVTLHLICPHKPEVWKFYAAVFKELKDIFPSGIVHLGGDEAPLEKTWAKCPLSIQYREQKGMKDVHEEL
KEFIKKMSSMLAVHGKRIQLWYEKPWARANIYNKGDTVFTWRMGLTPSTITETKKQGLSLIIAAGEYCYLDYPQLPGQSN
RGWMPTTTLEQSYRLDPAYGRPEKETNHITGVQGTVWGEHLPTLNHILYRAYPRACAIAEAGWSPMNVRSWENFRRKLAD
HRQFILKRFNYDMERTKENEPPFK

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=448, Percent_Identity=28.5714285714286, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI189181666, Length=467, Percent_Identity=26.9807280513919, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17569815, Length=360, Percent_Identity=26.6666666666667, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281365639, Length=475, Percent_Identity=22.9473684210526, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24657474, Length=475, Percent_Identity=22.9473684210526, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24657468, Length=475, Percent_Identity=22.9473684210526, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI17647501, Length=475, Percent_Identity=22.9473684210526, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI45551090, Length=473, Percent_Identity=22.8329809725159, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24653074, Length=473, Percent_Identity=22.8329809725159, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 57607; Mature: 57607

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVESFPKQFFMMFKLPLILACAIFSAHMACAAAADKYSVIPEPEKTELQHNSTRTLKLLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEEC
DQEAPTLGTDAYRLTVTPQGAHLASGGREGRIYGLATLRQLRDQLAGQPEGIPCGVITDK
CCCCCCCCCCCEEEEECCCCCEECCCCCCCEEEHHHHHHHHHHHHCCCCCCCEEEEECCC
PRYPWRGLMVDPARFFIPTADLKKFVDMMAYYKFNKLQIHLTDDQGWRLPVPGYPKLKSI
CCCCCCCEEECCHHHEECHHHHHHHHHHHHHHEECEEEEEEECCCCCEECCCCCCCHHHH
SSKRKESMRNGIPHEGMYTKQELKELVAYCAARGIEVIPEIDVPGHNQALAAAYPEFFCF
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHCCCEEEC
PNPDTKVKTDEGVTLHLICPHKPEVWKFYAAVFKELKDIFPSGIVHLGGDEAPLEKTWAK
CCCCCCEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
CPLSIQYREQKGMKDVHEELKEFIKKMSSMLAVHGKRIQLWYEKPWARANIYNKGDTVFT
CCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEE
WRMGLTPSTITETKKQGLSLIIAAGEYCYLDYPQLPGQSNRGWMPTTTLEQSYRLDPAYG
EEECCCCHHHHHHHHCCCEEEEEECCEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCC
RPEKETNHITGVQGTVWGEHLPTLNHILYRAYPRACAIAEAGWSPMNVRSWENFRRKLAD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHH
HRQFILKRFNYDMERTKENEPPFK
HHHHHHHHHCCCHHHCCCCCCCCC
>Mature Secondary Structure
MVESFPKQFFMMFKLPLILACAIFSAHMACAAAADKYSVIPEPEKTELQHNSTRTLKLLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEEEEC
DQEAPTLGTDAYRLTVTPQGAHLASGGREGRIYGLATLRQLRDQLAGQPEGIPCGVITDK
CCCCCCCCCCCEEEEECCCCCEECCCCCCCEEEHHHHHHHHHHHHCCCCCCCEEEEECCC
PRYPWRGLMVDPARFFIPTADLKKFVDMMAYYKFNKLQIHLTDDQGWRLPVPGYPKLKSI
CCCCCCCEEECCHHHEECHHHHHHHHHHHHHHEECEEEEEEECCCCCEECCCCCCCHHHH
SSKRKESMRNGIPHEGMYTKQELKELVAYCAARGIEVIPEIDVPGHNQALAAAYPEFFCF
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHCCCEEEC
PNPDTKVKTDEGVTLHLICPHKPEVWKFYAAVFKELKDIFPSGIVHLGGDEAPLEKTWAK
CCCCCCEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
CPLSIQYREQKGMKDVHEELKEFIKKMSSMLAVHGKRIQLWYEKPWARANIYNKGDTVFT
CCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEE
WRMGLTPSTITETKKQGLSLIIAAGEYCYLDYPQLPGQSNRGWMPTTTLEQSYRLDPAYG
EEECCCCHHHHHHHHCCCEEEEEECCEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCC
RPEKETNHITGVQGTVWGEHLPTLNHILYRAYPRACAIAEAGWSPMNVRSWENFRRKLAD
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHH
HRQFILKRFNYDMERTKENEPPFK
HHHHHHHHHCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]