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The map label for this gene is nahA [H]

Identifier: 187736497

GI number: 187736497

Start: 2450608

End: 2452089

Strand: Direct

Name: nahA [H]

Synonym: Amuc_2018

Alternate gene names: 187736497

Gene position: 2450608-2452089 (Clockwise)

Preceding gene: 187736496

Following gene: 187736498

Centisome position: 91.99

GC content: 57.76

Gene sequence:

>1482_bases
ATGGCACGTCCCTTACCCATTCTCGGCGGCATTCTGCTATCCTTCTCCCCTCCGGCAGAAGCAACAGCCCAATACAGCAT
TATCCCTGAGCCGTCCAGAACGGAACTCAGACAGGAAACAGCTAAAACTTTACAGCTTCTTTCCGACCAGGAAGTTCCGA
CCCTGGAAACGGACGCCTACCGGCTCACGGTCACCCCGCAGGGGGCGCACCTTGCTTCCGGAGGAAGGGAAGGCAGAATT
TACGGGCTGGCAACCCTCCGCCAGCTCCGGGACCAGCTGGCGGGACAGCCGGAGGGCATTCCCTGCGGCGTCATCACGGA
CAAGCCGCGCTATCCGTGGCGCGGCCTCATGGTGGATCCCGCGCGGCATTTCATCCCCGCGGCCGATCTGAAAAAATTTG
TGGATATGATGGCCTACTACAAATTCAACAGGCTGCACCTGCATCTGACGGACAACCAGGGCTGGAGGCTGCCCGTGCCC
GGCTACCCCAAATTGAAAAGCGTCGCATCCAGGCGGGAGGAAAGCTTCGGAGACGGAATCCCCCACGAAGGGATGTACAC
CAAACAGGAACTGAAGGAACTGGTGGCGTACTGCGCAGCGCGCGGCATTGATGTCATCCCTGAAATAGACATGCCGGGCC
ACAACCAGGCGCTTCATGCCGCCTACCCGGAATTTTTCTGCTTCCCCAAACCGGACATGAACGTGCGGACGACAGCGGGA
AACAGCAAGGAACTGGTCTGTCCCCAGAAGCCGGAAGTCTGGAAATTTTATGCCTCCGTCTTTAATGAACTCAAGGATAT
CTTCCCGTCCGGTATCGTTCATCTGGGCGGGGACGAGGCCCCCACGGAACTCTGGGAAAAATGCCCTCTGTGCCGGGAAG
CCCGGACCAGGGCAGCCATGAAAGACGAACAGGAACAGATGAAAGCCTTTTTTGCGAAAACGGCAGCTCTGCTTGCCAAA
AACGGGCAAACGCCGCAATTCTGGTATGAGGGGAACGCCGGCATTTACCATCCGGGGGAAACGGTTTACGCATGGCGGCA
AGGCCAGGCCCTCCAGTCCATTGAGAAGACGAAAAAGGCGGGATTGAACCTGATTATGGCCTCCAGCGAATACTGTTACC
TGGATTTTCCCCAGATTCAGGGGCAGCGCAACTGGGGATGGATGAAAACCACCACCCTGCAAAAATGTTATGACCTGGAT
CCCGCTTTTGGAAAACCGGAGAAAGAGGCAGGCCATATCCGGGGCGTGCATGCCCCCGTATGGGCGGAACGCCTGCCGGA
CTTGAACCACTTGCTTTACCGCGCCTATCCCCGCGCCTGCGCCATTGCGGAAGCCGGCTGGTCACCGATGGGCGTGCGCT
CCTGGGAAAACTTCCGGCGCAAGCTGGCCGACCACCGTCAATTCATCCTCAAACGCTTCAATTATGATATGGAGCGCACT
CAGGGGAATGAACCGGCCTTCCGCTGGGAAAACAACAAGTAA

Upstream 100 bases:

>100_bases
TTACCGATTCCGCTCTGGACAACAAGGAGACGGCAAAAAATCTGGAAGCAAAAGATGATTCTTTGACAGAACCTGTTTCC
TCCCCGTTTATATTGGAAAT

Downstream 100 bases:

>100_bases
TTTCACCGTTTTTCCTTATCACGCATCCCTTACCATGGTAGAATCTTTTCCGAAACAGTTCTTCATGATGTTTAAACTGC
CCCTCATCCTGGCCTGCGCC

Product: Beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MARPLPILGGILLSFSPPAEATAQYSIIPEPSRTELRQETAKTLQLLSDQEVPTLETDAYRLTVTPQGAHLASGGREGRI
YGLATLRQLRDQLAGQPEGIPCGVITDKPRYPWRGLMVDPARHFIPAADLKKFVDMMAYYKFNRLHLHLTDNQGWRLPVP
GYPKLKSVASRREESFGDGIPHEGMYTKQELKELVAYCAARGIDVIPEIDMPGHNQALHAAYPEFFCFPKPDMNVRTTAG
NSKELVCPQKPEVWKFYASVFNELKDIFPSGIVHLGGDEAPTELWEKCPLCREARTRAAMKDEQEQMKAFFAKTAALLAK
NGQTPQFWYEGNAGIYHPGETVYAWRQGQALQSIEKTKKAGLNLIMASSEYCYLDFPQIQGQRNWGWMKTTTLQKCYDLD
PAFGKPEKEAGHIRGVHAPVWAERLPDLNHLLYRAYPRACAIAEAGWSPMGVRSWENFRRKLADHRQFILKRFNYDMERT
QGNEPAFRWENNK

Sequences:

>Translated_493_residues
MARPLPILGGILLSFSPPAEATAQYSIIPEPSRTELRQETAKTLQLLSDQEVPTLETDAYRLTVTPQGAHLASGGREGRI
YGLATLRQLRDQLAGQPEGIPCGVITDKPRYPWRGLMVDPARHFIPAADLKKFVDMMAYYKFNRLHLHLTDNQGWRLPVP
GYPKLKSVASRREESFGDGIPHEGMYTKQELKELVAYCAARGIDVIPEIDMPGHNQALHAAYPEFFCFPKPDMNVRTTAG
NSKELVCPQKPEVWKFYASVFNELKDIFPSGIVHLGGDEAPTELWEKCPLCREARTRAAMKDEQEQMKAFFAKTAALLAK
NGQTPQFWYEGNAGIYHPGETVYAWRQGQALQSIEKTKKAGLNLIMASSEYCYLDFPQIQGQRNWGWMKTTTLQKCYDLD
PAFGKPEKEAGHIRGVHAPVWAERLPDLNHLLYRAYPRACAIAEAGWSPMGVRSWENFRRKLADHRQFILKRFNYDMERT
QGNEPAFRWENNK
>Mature_492_residues
ARPLPILGGILLSFSPPAEATAQYSIIPEPSRTELRQETAKTLQLLSDQEVPTLETDAYRLTVTPQGAHLASGGREGRIY
GLATLRQLRDQLAGQPEGIPCGVITDKPRYPWRGLMVDPARHFIPAADLKKFVDMMAYYKFNRLHLHLTDNQGWRLPVPG
YPKLKSVASRREESFGDGIPHEGMYTKQELKELVAYCAARGIDVIPEIDMPGHNQALHAAYPEFFCFPKPDMNVRTTAGN
SKELVCPQKPEVWKFYASVFNELKDIFPSGIVHLGGDEAPTELWEKCPLCREARTRAAMKDEQEQMKAFFAKTAALLAKN
GQTPQFWYEGNAGIYHPGETVYAWRQGQALQSIEKTKKAGLNLIMASSEYCYLDFPQIQGQRNWGWMKTTTLQKCYDLDP
AFGKPEKEAGHIRGVHAPVWAERLPDLNHLLYRAYPRACAIAEAGWSPMGVRSWENFRRKLADHRQFILKRFNYDMERTQ
GNEPAFRWENNK

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=454, Percent_Identity=25.9911894273128, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI189181666, Length=458, Percent_Identity=27.9475982532751, Blast_Score=153, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17569815, Length=357, Percent_Identity=27.1708683473389, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24657468, Length=472, Percent_Identity=25.4237288135593, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI17647501, Length=472, Percent_Identity=25.4237288135593, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI281365639, Length=472, Percent_Identity=25.2118644067797, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24657474, Length=472, Percent_Identity=25.2118644067797, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24653074, Length=419, Percent_Identity=25.2983293556086, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45551090, Length=424, Percent_Identity=25.4716981132075, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17933586, Length=466, Percent_Identity=23.3905579399142, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 56045; Mature: 55913

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPLPILGGILLSFSPPAEATAQYSIIPEPSRTELRQETAKTLQLLSDQEVPTLETDAY
CCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCE
RLTVTPQGAHLASGGREGRIYGLATLRQLRDQLAGQPEGIPCGVITDKPRYPWRGLMVDP
EEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEECC
ARHFIPAADLKKFVDMMAYYKFNRLHLHLTDNQGWRLPVPGYPKLKSVASRREESFGDGI
HHHHCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHCCCC
PHEGMYTKQELKELVAYCAARGIDVIPEIDMPGHNQALHAAYPEFFCFPKPDMNVRTTAG
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCEECCCCCCCEEECCC
NSKELVCPQKPEVWKFYASVFNELKDIFPSGIVHLGGDEAPTELWEKCPLCREARTRAAM
CCCCEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHH
KDEQEQMKAFFAKTAALLAKNGQTPQFWYEGNAGIYHPGETVYAWRQGQALQSIEKTKKA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCCEEEEECCCHHHHHHHHHHHC
GLNLIMASSEYCYLDFPQIQGQRNWGWMKTTTLQKCYDLDPAFGKPEKEAGHIRGVHAPV
CCEEEEECCCEEEEECHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
WAERLPDLNHLLYRAYPRACAIAEAGWSPMGVRSWENFRRKLADHRQFILKRFNYDMERT
HHHHCCCHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
QGNEPAFRWENNK
CCCCCCEECCCCC
>Mature Secondary Structure 
ARPLPILGGILLSFSPPAEATAQYSIIPEPSRTELRQETAKTLQLLSDQEVPTLETDAY
CCCCCHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCE
RLTVTPQGAHLASGGREGRIYGLATLRQLRDQLAGQPEGIPCGVITDKPRYPWRGLMVDP
EEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEECC
ARHFIPAADLKKFVDMMAYYKFNRLHLHLTDNQGWRLPVPGYPKLKSVASRREESFGDGI
HHHHCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHCCCC
PHEGMYTKQELKELVAYCAARGIDVIPEIDMPGHNQALHAAYPEFFCFPKPDMNVRTTAG
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCEECCCCCCCEEECCC
NSKELVCPQKPEVWKFYASVFNELKDIFPSGIVHLGGDEAPTELWEKCPLCREARTRAAM
CCCCEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHH
KDEQEQMKAFFAKTAALLAKNGQTPQFWYEGNAGIYHPGETVYAWRQGQALQSIEKTKKA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCCEEEEECCCHHHHHHHHHHHC
GLNLIMASSEYCYLDFPQIQGQRNWGWMKTTTLQKCYDLDPAFGKPEKEAGHIRGVHAPV
CCEEEEECCCEEEEECHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
WAERLPDLNHLLYRAYPRACAIAEAGWSPMGVRSWENFRRKLADHRQFILKRFNYDMERT
HHHHCCCHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
QGNEPAFRWENNK
CCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]