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The map label for this gene is argK [C]

Identifier: 187736499

GI number: 187736499

Start: 2453657

End: 2454676

Strand: Direct

Name: argK [C]

Synonym: Amuc_2020

Alternate gene names: 187736499

Gene position: 2453657-2454676 (Clockwise)

Preceding gene: 187736498

Following gene: 187736501

Centisome position: 92.1

GC content: 59.22

Gene sequence:

>1020_bases
ATGAGCAACATCAAATTTGCACGTCCGCACCGCCCTTCCGTAGAAGAACTGGCCCAGGGAGTACTGGCCGGAAACCGCGC
CCTGCTGGGAAGGGCCATTACACTGATAGAAAGCAATGCCGTCCGGGACCAGGAATCTTCCCGCGCCCTCATCTCCAGGC
TCCTTCCCCATTCGGGCAACGCCGTCCGCATCGGCATTACGGGCGTTCCGGGCGCCGGGAAATCCTCTTTCATTGAAGCC
TTCGGCACTTACCTGTGCAAAAAAGGGTTCAAGGTGGCTGTGCTGGCTATTGACCCGTCTTCTTCAGTCTCCCGCGGTTC
CATTATGGGAGACAAAACACGCATGGAGGAACTCTCCGGAGAGGAAAACGCCTTCATCCGCCCTTCCCCCTCCGGCGGCT
CTTTGGGCGGCGTAGCCCGGAAAACGCGTGAAACCATGATTGCATGCGAAGCTGCGGGCTTTGACATTATTCTCATTGAA
ACCGTGGGAGTCGGCCAGTCGGAAACTACGGTGCGCTCCATGGTGGACATTTTCATGCTCCTGCTCATCACCGGAGCCGG
GGACGATCTCCAGGGCATCAAGCGGGGCATCATGGAACTGGCGGATATCCTAGTAGTTACCAAAGATGACGGCGACAACC
GCCAGCGCGCCGCAGCCCACTGCCAGGAACTGAAAATGGTACTCCACTACCTGCAAAGCCCCACTCCCGGCTGGACGCCC
TCCGTCCTCACCTGTTCCTCCCTGGAGGGACGCGGCCTGGACACCATTGAAGAGACGCTCTTCCGCTTCCGGGACAGCAT
GAAGGAATCCGGATTCTGGTACAGCCGCCGCCGGAGCCAGTCCCTTTCATGGGTCCAGTCCCTGGTGCATGAAGCCCTGC
TCACCGCTTTTGAACAGCACCCCGCCGTAGCGTCCCGCATGCCCATTCTGGAAAACATGGTGGCGGGGGACAAAATGGAC
CCCGTTTCCGCCGCACATGACCTGCTGAGCCACTTTACTTATCCCGCGCCCGGACATTAA

Upstream 100 bases:

>100_bases
GGCCGACCACCGTCAATTCATCCTCAAACGCTTCAATTATGATATGGAGCGCACCAAAGAAAACGAACCGCCTTTCAAAT
AATCCGCACTCTCTTTTCCC

Downstream 100 bases:

>100_bases
AGAAATCTTCCAGAACCCTGGCGTAAACTTTCTTTTTAAACTCCGGCAGCCACTCCAGCTTAAATTCGGCTGGGGCTATC
CACTTGTAATCGCAAAACTC

Product: LAO/AO transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSNIKFARPHRPSVEELAQGVLAGNRALLGRAITLIESNAVRDQESSRALISRLLPHSGNAVRIGITGVPGAGKSSFIEA
FGTYLCKKGFKVAVLAIDPSSSVSRGSIMGDKTRMEELSGEENAFIRPSPSGGSLGGVARKTRETMIACEAAGFDIILIE
TVGVGQSETTVRSMVDIFMLLLITGAGDDLQGIKRGIMELADILVVTKDDGDNRQRAAAHCQELKMVLHYLQSPTPGWTP
SVLTCSSLEGRGLDTIEETLFRFRDSMKESGFWYSRRRSQSLSWVQSLVHEALLTAFEQHPAVASRMPILENMVAGDKMD
PVSAAHDLLSHFTYPAPGH

Sequences:

>Translated_339_residues
MSNIKFARPHRPSVEELAQGVLAGNRALLGRAITLIESNAVRDQESSRALISRLLPHSGNAVRIGITGVPGAGKSSFIEA
FGTYLCKKGFKVAVLAIDPSSSVSRGSIMGDKTRMEELSGEENAFIRPSPSGGSLGGVARKTRETMIACEAAGFDIILIE
TVGVGQSETTVRSMVDIFMLLLITGAGDDLQGIKRGIMELADILVVTKDDGDNRQRAAAHCQELKMVLHYLQSPTPGWTP
SVLTCSSLEGRGLDTIEETLFRFRDSMKESGFWYSRRRSQSLSWVQSLVHEALLTAFEQHPAVASRMPILENMVAGDKMD
PVSAAHDLLSHFTYPAPGH
>Mature_338_residues
SNIKFARPHRPSVEELAQGVLAGNRALLGRAITLIESNAVRDQESSRALISRLLPHSGNAVRIGITGVPGAGKSSFIEAF
GTYLCKKGFKVAVLAIDPSSSVSRGSIMGDKTRMEELSGEENAFIRPSPSGGSLGGVARKTRETMIACEAAGFDIILIET
VGVGQSETTVRSMVDIFMLLLITGAGDDLQGIKRGIMELADILVVTKDDGDNRQRAAAHCQELKMVLHYLQSPTPGWTPS
VLTCSSLEGRGLDTIEETLFRFRDSMKESGFWYSRRRSQSLSWVQSLVHEALLTAFEQHPAVASRMPILENMVAGDKMDP
VSAAHDLLSHFTYPAPGH

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=333, Percent_Identity=45.3453453453453, Blast_Score=278, Evalue=6e-75,
Organism=Escherichia coli, GI1789285, Length=272, Percent_Identity=50.7352941176471, Blast_Score=288, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI71994271, Length=332, Percent_Identity=42.1686746987952, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71994275, Length=271, Percent_Identity=46.1254612546125, Blast_Score=245, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 36695; Mature: 36564

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIKFARPHRPSVEELAQGVLAGNRALLGRAITLIESNAVRDQESSRALISRLLPHSGN
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
AVRIGITGVPGAGKSSFIEAFGTYLCKKGFKVAVLAIDPSSSVSRGSIMGDKTRMEELSG
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCC
EENAFIRPSPSGGSLGGVARKTRETMIACEAAGFDIILIETVGVGQSETTVRSMVDIFML
CCCCEECCCCCCCCCCHHHHHHHHHHHHEECCCCEEEEEEEECCCCCHHHHHHHHHHHHH
LLITGAGDDLQGIKRGIMELADILVVTKDDGDNRQRAAAHCQELKMVLHYLQSPTPGWTP
HHHHCCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
SVLTCSSLEGRGLDTIEETLFRFRDSMKESGFWYSRRRSQSLSWVQSLVHEALLTAFEQH
CEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAVASRMPILENMVAGDKMDPVSAAHDLLSHFTYPAPGH
CHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SNIKFARPHRPSVEELAQGVLAGNRALLGRAITLIESNAVRDQESSRALISRLLPHSGN
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
AVRIGITGVPGAGKSSFIEAFGTYLCKKGFKVAVLAIDPSSSVSRGSIMGDKTRMEELSG
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCC
EENAFIRPSPSGGSLGGVARKTRETMIACEAAGFDIILIETVGVGQSETTVRSMVDIFML
CCCCEECCCCCCCCCCHHHHHHHHHHHHEECCCCEEEEEEEECCCCCHHHHHHHHHHHHH
LLITGAGDDLQGIKRGIMELADILVVTKDDGDNRQRAAAHCQELKMVLHYLQSPTPGWTP
HHHHCCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
SVLTCSSLEGRGLDTIEETLFRFRDSMKESGFWYSRRRSQSLSWVQSLVHEALLTAFEQH
CEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAVASRMPILENMVAGDKMDPVSAAHDLLSHFTYPAPGH
CHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]