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The map label for this gene is gbsB [H]

Identifier: 187736394

GI number: 187736394

Start: 2317939

End: 2319099

Strand: Direct

Name: gbsB [H]

Synonym: Amuc_1911

Alternate gene names: 187736394

Gene position: 2317939-2319099 (Clockwise)

Preceding gene: 187736393

Following gene: 187736399

Centisome position: 87.01

GC content: 55.64

Gene sequence:

>1161_bases
ATGTATCAGCCATTTCAATTTTTCATGCCCGCGCAAATCTTTTTTGGCGCGGGTTCTTTGGACAATCTTGGTTCCGCTCC
CCTGCCCGGCACCAAGGCCCTGATCGTCATCGGCGGGTCGTCCGTCAAACGCCTCGGGTATCTGGACCGCGTACAGGCTC
TTCTGAAAAAACAGGGAGTGGAAAGCGTTGTTTTCGATAAAGTGCAGCCCAACCCCGTGGTGGAGCACGTAATGGAAGCC
TCCTCCCTGGCCAGGGAAACGGGCTGTGATTTCGTCATCGGCCTGGGCGGGGGCAGCAGCATGGATTCCGCCAAGAGCAT
CGCCGTGATGGCGGCCAATCCAGGAACCTACTGGGATTACATCCAGGGAGGTTCCGGCAAGGGGCTTCCCATTCCCTGCA
AACCTCTTCCCATCGTCTGCATCACCACTACGGCGGGAACCGGAACGGAGGCGGATCCGTGGACCGTCATCACGAAAGAG
GACACGCAGGAGAAGATCGGTTTCGGGTTCAAGGGTACTTTCCCCACCATGTCTATCGTAGATCCGGAGTTGATGCTTTC
CGTACCTCCCAAATTAACGGCATACCAGGGGTTTGACGCTTTGTTCCATGCCGTGGAGGGATATATGGCTACAATCGCCT
CCCCCATGGGGGACATGTTCGCGCTCCAGGCTATTGAATACATTGCCAAATATCTTCCGCGCGCCGTAAATAACGGGGAT
GATCTGGAAGCGCGCGCCTATGTGGCGCTGGCCAATACCTATTCCGGGTTTGTGGAAACCATTTCCTGCTGTACGTCGGA
ACATTCCATTGAACATGCCCTCAGCGCCTTCCATCCTTCCCTGCCCCATGGCGCGGGGCTAATTATGATTTCCTGGGCCT
ACCATGAAGCCTATGCTCCCTCCTGCCCGGAACGTTACGCAAGAGTTGCCGCAGCCATGGGACAGGAAGCCTCCGTGGAC
GGTTTCCTGAACGGCTTGAACAGCCTGAAGGAAGCCTGCGGCGTAGACAAGCTGAAGATGTCCGAATTCGGCATTACACC
GGATTTATTTGACGAATACGCCAAAACGGCTTTTTCCACCATGGGCAATCTGTTTGAGCTGGACCGTTGCAAGTTGACTC
CGGCGGACGTGGTCAGCATCCTGGAGAAATCCTATTCCTAG

Upstream 100 bases:

>100_bases
TTCTTCAGACAAAAGATGTTGCCCGAACGGCGGTTTCCCTGTTCATGGAATGCGCAGAGCATCCTTGACGTCCGGAGCCG
CCGTTTTATACATTAAGGGC

Downstream 100 bases:

>100_bases
GAACAAACTTCCGGGGCTATCGCCCGCAGGGAATATCCCTGCGGGCGCGAGAGATTTAGCTCAGCCGCGGCATTACCAAG
ACGAACGCGGCGCGTATGAT

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MYQPFQFFMPAQIFFGAGSLDNLGSAPLPGTKALIVIGGSSVKRLGYLDRVQALLKKQGVESVVFDKVQPNPVVEHVMEA
SSLARETGCDFVIGLGGGSSMDSAKSIAVMAANPGTYWDYIQGGSGKGLPIPCKPLPIVCITTTAGTGTEADPWTVITKE
DTQEKIGFGFKGTFPTMSIVDPELMLSVPPKLTAYQGFDALFHAVEGYMATIASPMGDMFALQAIEYIAKYLPRAVNNGD
DLEARAYVALANTYSGFVETISCCTSEHSIEHALSAFHPSLPHGAGLIMISWAYHEAYAPSCPERYARVAAAMGQEASVD
GFLNGLNSLKEACGVDKLKMSEFGITPDLFDEYAKTAFSTMGNLFELDRCKLTPADVVSILEKSYS

Sequences:

>Translated_386_residues
MYQPFQFFMPAQIFFGAGSLDNLGSAPLPGTKALIVIGGSSVKRLGYLDRVQALLKKQGVESVVFDKVQPNPVVEHVMEA
SSLARETGCDFVIGLGGGSSMDSAKSIAVMAANPGTYWDYIQGGSGKGLPIPCKPLPIVCITTTAGTGTEADPWTVITKE
DTQEKIGFGFKGTFPTMSIVDPELMLSVPPKLTAYQGFDALFHAVEGYMATIASPMGDMFALQAIEYIAKYLPRAVNNGD
DLEARAYVALANTYSGFVETISCCTSEHSIEHALSAFHPSLPHGAGLIMISWAYHEAYAPSCPERYARVAAAMGQEASVD
GFLNGLNSLKEACGVDKLKMSEFGITPDLFDEYAKTAFSTMGNLFELDRCKLTPADVVSILEKSYS
>Mature_386_residues
MYQPFQFFMPAQIFFGAGSLDNLGSAPLPGTKALIVIGGSSVKRLGYLDRVQALLKKQGVESVVFDKVQPNPVVEHVMEA
SSLARETGCDFVIGLGGGSSMDSAKSIAVMAANPGTYWDYIQGGSGKGLPIPCKPLPIVCITTTAGTGTEADPWTVITKE
DTQEKIGFGFKGTFPTMSIVDPELMLSVPPKLTAYQGFDALFHAVEGYMATIASPMGDMFALQAIEYIAKYLPRAVNNGD
DLEARAYVALANTYSGFVETISCCTSEHSIEHALSAFHPSLPHGAGLIMISWAYHEAYAPSCPERYARVAAAMGQEASVD
GFLNGLNSLKEACGVDKLKMSEFGITPDLFDEYAKTAFSTMGNLFELDRCKLTPADVVSILEKSYS

Specific function: Essential for the utilization of choline as a precursor [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=319, Percent_Identity=28.8401253918495, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI48994951, Length=280, Percent_Identity=37.5, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1787493, Length=385, Percent_Identity=30.3896103896104, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI87082107, Length=355, Percent_Identity=30.7042253521127, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1789386, Length=292, Percent_Identity=30.4794520547945, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789163, Length=355, Percent_Identity=28.7323943661972, Blast_Score=122, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17537053, Length=356, Percent_Identity=25.2808988764045, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321181, Length=383, Percent_Identity=28.4595300261097, Blast_Score=167, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24657991, Length=319, Percent_Identity=26.6457680250784, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 41350; Mature: 41350

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQPFQFFMPAQIFFGAGSLDNLGSAPLPGTKALIVIGGSSVKRLGYLDRVQALLKKQGV
CCCCHHHHCCHHHEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
ESVVFDKVQPNPVVEHVMEASSLARETGCDFVIGLGGGSSMDSAKSIAVMAANPGTYWDY
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCHH
IQGGSGKGLPIPCKPLPIVCITTTAGTGTEADPWTVITKEDTQEKIGFGFKGTFPTMSIV
EECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCC
DPELMLSVPPKLTAYQGFDALFHAVEGYMATIASPMGDMFALQAIEYIAKYLPRAVNNGD
CHHHEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DLEARAYVALANTYSGFVETISCCTSEHSIEHALSAFHPSLPHGAGLIMISWAYHEAYAP
CCCCEEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHCCCC
SCPERYARVAAAMGQEASVDGFLNGLNSLKEACGVDKLKMSEFGITPDLFDEYAKTAFST
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEHHHCCCCHHHHHHHHHHHHHH
MGNLFELDRCKLTPADVVSILEKSYS
HHHHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MYQPFQFFMPAQIFFGAGSLDNLGSAPLPGTKALIVIGGSSVKRLGYLDRVQALLKKQGV
CCCCHHHHCCHHHEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
ESVVFDKVQPNPVVEHVMEASSLARETGCDFVIGLGGGSSMDSAKSIAVMAANPGTYWDY
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCHH
IQGGSGKGLPIPCKPLPIVCITTTAGTGTEADPWTVITKEDTQEKIGFGFKGTFPTMSIV
EECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCC
DPELMLSVPPKLTAYQGFDALFHAVEGYMATIASPMGDMFALQAIEYIAKYLPRAVNNGD
CHHHEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DLEARAYVALANTYSGFVETISCCTSEHSIEHALSAFHPSLPHGAGLIMISWAYHEAYAP
CCCCEEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHCCCC
SCPERYARVAAAMGQEASVDGFLNGLNSLKEACGVDKLKMSEFGITPDLFDEYAKTAFST
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEHHHCCCCHHHHHHHHHHHHHH
MGNLFELDRCKLTPADVVSILEKSYS
HHHHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8752328; 9384377 [H]