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The map label for this gene is yccK [H]

Identifier: 187736294

GI number: 187736294

Start: 2194075

End: 2195019

Strand: Direct

Name: yccK [H]

Synonym: Amuc_1807

Alternate gene names: 187736294

Gene position: 2194075-2195019 (Clockwise)

Preceding gene: 187736293

Following gene: 187736295

Centisome position: 82.36

GC content: 51.75

Gene sequence:

>945_bases
ATGAAAAATCAGTCTAAAATTGCATTAGGGACATGGTCATGGGGCGCAGGATTTGCCGGAGGCGACCAGGTATTCGGCAA
TAATCTCGGAGTAGACGAGCTGAGACCCGTATTCGACGAGGCGATGGCAAACGGGGTGAATTTGTGGGATTCTGCCGTGG
TGTATGGTATGGGTACTTCAGAAACGTTGCTCTCGACATTTACAAAGAATAGAAAGCGGGAGGATATATTTATCTCGACC
AAGTTCACTCCGCAGATTGCAGGCGAGTCGGAAGATCCGGTAGCCGATATGCTGGCAGGGAGCCTCGAACGTTTCGCCAC
CGGTTACGTCGATATTTATTGGATACATAATCCGGCCGACGTGGAAAGATGGACGCCTTATCTTATTCCACTGGTAAAAA
GCGGTAAGGTAAAAAGAGTCGGTGTTTCCAACCATAACCTCGCGCAGATCAAACGTGTGGAGGAAATTCTCTCGCAAGAA
GGGATACATCTCTCTGCCGTTCAGAACCATTACAGCCTGCTCTACCTCTCGTCAGAAAAGGCAGGCATTCTGGATTACTG
CAGGGAGAACGGCATCGACTTTTGGGCTTACATGGTGCTGGAACAGGGGGCGTTGAGCGGAAAATACGATACCGCGCACC
CGTTGCCAGCCGATAGCCAGCGTGGGAAAACCTACAATCCGCTGCTGCCGCAAATAGAAAAACTCGTTGCCGTGATGCGC
ACCGTGGGCGATAAGTACGATATTACGCCGGCGCAGGTGGCTCTGGCATGGGCGATAACGAAGGGCACGACGCCGATTAT
TGGTGTGACGAAACCCTCACAAGTGCAGGATGCTGTCCGTGCCATGCAGGTCGTGCTGACTGTTGACGAAGTGAAGATGT
TGGAGGATGCGGCCGAAAGCACGGGGGTAGATACGAGAGGTTCATGGGAAAATCCGATGATATGA

Upstream 100 bases:

>100_bases
GAACCTGTATGAGCCTTTTATTTCACATCGGCAGTCATTGTGGGGACAATAATAGAAAACAGTCTTATGCGGTTTAAAAA
ATATAATAAAAGAATACGAA

Downstream 100 bases:

>100_bases
TGAGGCTGGTTATAATCATCGGAGTTGTCCTGTCTGTATGGTTTGCGGATTGGGCGGCGGCACAGCAGATTGTGGATGTG
CATTGCCATAACATTATGTC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKNQSKIALGTWSWGAGFAGGDQVFGNNLGVDELRPVFDEAMANGVNLWDSAVVYGMGTSETLLSTFTKNRKREDIFIST
KFTPQIAGESEDPVADMLAGSLERFATGYVDIYWIHNPADVERWTPYLIPLVKSGKVKRVGVSNHNLAQIKRVEEILSQE
GIHLSAVQNHYSLLYLSSEKAGILDYCRENGIDFWAYMVLEQGALSGKYDTAHPLPADSQRGKTYNPLLPQIEKLVAVMR
TVGDKYDITPAQVALAWAITKGTTPIIGVTKPSQVQDAVRAMQVVLTVDEVKMLEDAAESTGVDTRGSWENPMI

Sequences:

>Translated_314_residues
MKNQSKIALGTWSWGAGFAGGDQVFGNNLGVDELRPVFDEAMANGVNLWDSAVVYGMGTSETLLSTFTKNRKREDIFIST
KFTPQIAGESEDPVADMLAGSLERFATGYVDIYWIHNPADVERWTPYLIPLVKSGKVKRVGVSNHNLAQIKRVEEILSQE
GIHLSAVQNHYSLLYLSSEKAGILDYCRENGIDFWAYMVLEQGALSGKYDTAHPLPADSQRGKTYNPLLPQIEKLVAVMR
TVGDKYDITPAQVALAWAITKGTTPIIGVTKPSQVQDAVRAMQVVLTVDEVKMLEDAAESTGVDTRGSWENPMI
>Mature_314_residues
MKNQSKIALGTWSWGAGFAGGDQVFGNNLGVDELRPVFDEAMANGVNLWDSAVVYGMGTSETLLSTFTKNRKREDIFIST
KFTPQIAGESEDPVADMLAGSLERFATGYVDIYWIHNPADVERWTPYLIPLVKSGKVKRVGVSNHNLAQIKRVEEILSQE
GIHLSAVQNHYSLLYLSSEKAGILDYCRENGIDFWAYMVLEQGALSGKYDTAHPLPADSQRGKTYNPLLPQIEKLVAVMR
TVGDKYDITPAQVALAWAITKGTTPIIGVTKPSQVQDAVRAMQVVLTVDEVKMLEDAAESTGVDTRGSWENPMI

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=302, Percent_Identity=22.1854304635762, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI4504825, Length=302, Percent_Identity=22.1854304635762, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI87081735, Length=303, Percent_Identity=26.4026402640264, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788070, Length=327, Percent_Identity=27.82874617737, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789375, Length=282, Percent_Identity=26.5957446808511, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789199, Length=321, Percent_Identity=25.2336448598131, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788081, Length=256, Percent_Identity=25.390625, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17566692, Length=325, Percent_Identity=28.3076923076923, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17561300, Length=282, Percent_Identity=24.822695035461, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17552492, Length=295, Percent_Identity=24.406779661017, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320079, Length=230, Percent_Identity=30.8695652173913, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=332, Percent_Identity=23.4939759036145, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34573; Mature: 34573

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQSKIALGTWSWGAGFAGGDQVFGNNLGVDELRPVFDEAMANGVNLWDSAVVYGMGTS
CCCCCEEEEEECCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCH
ETLLSTFTKNRKREDIFISTKFTPQIAGESEDPVADMLAGSLERFATGYVDIYWIHNPAD
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCC
VERWTPYLIPLVKSGKVKRVGVSNHNLAQIKRVEEILSQEGIHLSAVQNHYSLLYLSSEK
HHHCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCC
AGILDYCRENGIDFWAYMVLEQGALSGKYDTAHPLPADSQRGKTYNPLLPQIEKLVAVMR
CCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
TVGDKYDITPAQVALAWAITKGTTPIIGVTKPSQVQDAVRAMQVVLTVDEVKMLEDAAES
HCCCCCCCCHHHHEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGVDTRGSWENPMI
CCCCCCCCCCCCCC
>Mature Secondary Structure
MKNQSKIALGTWSWGAGFAGGDQVFGNNLGVDELRPVFDEAMANGVNLWDSAVVYGMGTS
CCCCCEEEEEECCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCH
ETLLSTFTKNRKREDIFISTKFTPQIAGESEDPVADMLAGSLERFATGYVDIYWIHNPAD
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCC
VERWTPYLIPLVKSGKVKRVGVSNHNLAQIKRVEEILSQEGIHLSAVQNHYSLLYLSSEK
HHHCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCC
AGILDYCRENGIDFWAYMVLEQGALSGKYDTAHPLPADSQRGKTYNPLLPQIEKLVAVMR
CCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
TVGDKYDITPAQVALAWAITKGTTPIIGVTKPSQVQDAVRAMQVVLTVDEVKMLEDAAES
HCCCCCCCCHHHHEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGVDTRGSWENPMI
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]