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The map label for this gene is bga [H]

Identifier: 187736173

GI number: 187736173

Start: 2048214

End: 2050556

Strand: Direct

Name: bga [H]

Synonym: Amuc_1686

Alternate gene names: 187736173

Gene position: 2048214-2050556 (Clockwise)

Preceding gene: 187736172

Following gene: 187736175

Centisome position: 76.88

GC content: 56.89

Gene sequence:

>2343_bases
ATGAAATTATCCTTTTTCTCCGTTCTGCTTCTGGCAGGGCATCTTTGTGCGGCTGCTCCCATGCCTTTGCCGGAATCCAA
TGACGGAGCCAGGCATGTCTTCTCTACTAATCAGGAAAATTTTTTGATGGACGGAAAGCCCGTCAAAATCATTTCCGGGG
AAATGCATTATCCTCGCGTGCCGCGCCAGCACTGGAAGGACAGGTTCCAGCGCATAAAGGCCATGGGCATGAATACCGTC
TGCACTTATCTGTTCTGGAACGTGCATGAACCGGAACCCGGCAAATGGGACTTTTCCGGCAATCTGGATTTTGTGGAATT
CATCAAGGAGGCGCAGAAGGCCGGCCTGTGGGTCATTGTGCGTCCCGGGCCCTATGTGTGCGCGGAATGGGAATTCGGCG
GATTTCCCGGCTGGCTGCTGAAGGATGAAGATTTGAAAGTCCGTTCCCAGGATCCCCGCTTCCTGGAACCGGCCATGGCT
TATCTTAAAAAAGTCTGTTCCATGCTGGAACCTCTGCAGATTACCAAGGGAGGCCCCATCATCATGGCCCAGGTGGAAAA
TGAATACGGCTCCTATGGTTCTGACAAGGATTACGTGAAAAAGCATCTGGACGTTATCCGGAAAGAACTTCCGGGAGTTG
TTCCCTTCACGTCGGACGGCCCGAACGACTGGATGATCAAGAACGGCACGCTTCCGGGCGTTGTTCCCGCCATGAATTTC
GGCGGCGGAGCCAAGGGCGCTTTTGCGAATCTGGAGAAGCACAAGGGCAAAACGCCCCGCATCAACGGCGAATTCTGGGT
GGGCTGGTTTGACCACTGGGGCAAGCCCAAGAATGGCGGCAGTACGGAAGGTTTCAACCGAGACCTGAAGTGGATGCTGG
AAAATAACGTTTCCCCCAACCTATTCATGGCGCATGGGGGGACCTCCTTCGGCTTCATGAACGGGGCGAACTGGGAAGGC
GCCTACACGCCGGATGTAACCAATTACGACTACGGCGCCCCCATTTCCGAAAACGGAACCCTGACGGACCGCTACCGCAC
CTTCCGCCAGACTATTCAGGATTATTACGGTGATACGTACAAGCTTCCCGAACCTCCCGCCCAGCCGGAAATGATGGAGC
TGCCTCCCATCACGTTTACGGAAACAGCCGGCATGTTCTCCCGCCTGCCGCAGCCCGTCATCCGCAAGGAGCCCGTCCAC
ATGGAAGCCTTGGGGCAAAGCCTGGGCTTCATCCTGTACCGGACAAAGGTGAACGGCCCGGTGAAAGGAGAGCTGAAGAT
GAACAACATGCAGGACCGCGCCATCGTTTACGTGGACGGCAAGAGGCAGGGGGCGGCGGACCGCCGTTACAAGCAGGATT
CCTGTGACATTGTCATTCCCTCCGGACTTCACACGGTGGACATTTTTGTGGAAAACATGGGCCGCATCAACTTCGGCGGC
CAGATACAGGGCGAGCGCAAGGGCATCCGGGGCCCCATTACGCTGGACGGCAAAAAGCTGGAAAACTTCCTTATCTACAA
CTTCCCGTGCAAGGGGGTGGAGCTTATTCCCTTCTCCGGCAAGAAGCCGGCGGGCGACCAGCCCGTGTTCCACCGCGGGT
ATTTCAACGTTTCCAATCCCAAGGATACCTACTTGGATATGCGGGACGGCTGGAAGAAAGGCGTCGTGTGGGTGAATGGA
CGCAATCTGGGCCGCTTCTGGTTTATCGGCTCCCAGCAGGCTCTTTATTGCCCCGGAGAATACCTGAAGCCCGGGAAAAA
TGAAATCGTGGTGCTGGACGTGGACGGAGGTTCCGGCACGGTGAAGGGTGTGAAGGAAGCCATTTATGAAGTCAACAGGG
ACCCCGCCATGGCGGATGTCTTCCGCGTGGGCAAACCTGTGGCCCCCGCTGCCGGCCAGCTGGTGCACAAGGGTTCCTTC
GCCAAGGGGGCGGACCAGCAGGAAATCAAATTCCGCGCTCCTGTCCAGGCCCGTTACATAGCTATTGTCAGTAAAAACGC
TCATGACAACGGCCCCCATGCCGCCATTGCGGAGCTGAACTTCCTGGATGCCTCCGGCAATCTGCTCCCCCGCGAACAGT
GGTCCGTGGTTTATGCGGATTCCCATGAAACGACGGGAGAAGCCGCCCAGGCGGGACTGGTGATGGACAACCAGCCCACC
ACCTACTGGCATACCAAGTGGCAGGGGGACAACCCCAGGCATCCGCACATGATCGTGCTGGATCTGGGCAAGGTGCAGAA
ACTTTCAGGATTCCGCTACCTGCCGCGCCAGGACCGGGAAAACGGCCGCATCAAGGACTATGAAGTCTATGCGTCTCCCA
AGCCGTTCAAGCCTGCCAAGTAA

Upstream 100 bases:

>100_bases
AATAAAACCGGGTCACCGTCTCCTTTTTAAATTGAAAGGAGGTGGTTTTTCATCATAATCTCCCTCTCATTTACCGTAAT
TAATTATTAATTCCATAATC

Downstream 100 bases:

>100_bases
GATCCTCTGAATTGTTGAGCTTTTCCAGGGCCGCTCCCTCTCGGATGAGGGGGCGGCCTTATTGCGTCCGGATATTCCGG
AAGAAAACAGTACCCCCGCT

Product: Beta-galactosidase

Products: NA

Alternate protein names: Lactase [H]

Number of amino acids: Translated: 780; Mature: 780

Protein sequence:

>780_residues
MKLSFFSVLLLAGHLCAAAPMPLPESNDGARHVFSTNQENFLMDGKPVKIISGEMHYPRVPRQHWKDRFQRIKAMGMNTV
CTYLFWNVHEPEPGKWDFSGNLDFVEFIKEAQKAGLWVIVRPGPYVCAEWEFGGFPGWLLKDEDLKVRSQDPRFLEPAMA
YLKKVCSMLEPLQITKGGPIIMAQVENEYGSYGSDKDYVKKHLDVIRKELPGVVPFTSDGPNDWMIKNGTLPGVVPAMNF
GGGAKGAFANLEKHKGKTPRINGEFWVGWFDHWGKPKNGGSTEGFNRDLKWMLENNVSPNLFMAHGGTSFGFMNGANWEG
AYTPDVTNYDYGAPISENGTLTDRYRTFRQTIQDYYGDTYKLPEPPAQPEMMELPPITFTETAGMFSRLPQPVIRKEPVH
MEALGQSLGFILYRTKVNGPVKGELKMNNMQDRAIVYVDGKRQGAADRRYKQDSCDIVIPSGLHTVDIFVENMGRINFGG
QIQGERKGIRGPITLDGKKLENFLIYNFPCKGVELIPFSGKKPAGDQPVFHRGYFNVSNPKDTYLDMRDGWKKGVVWVNG
RNLGRFWFIGSQQALYCPGEYLKPGKNEIVVLDVDGGSGTVKGVKEAIYEVNRDPAMADVFRVGKPVAPAAGQLVHKGSF
AKGADQQEIKFRAPVQARYIAIVSKNAHDNGPHAAIAELNFLDASGNLLPREQWSVVYADSHETTGEAAQAGLVMDNQPT
TYWHTKWQGDNPRHPHMIVLDLGKVQKLSGFRYLPRQDRENGRIKDYEVYASPKPFKPAK

Sequences:

>Translated_780_residues
MKLSFFSVLLLAGHLCAAAPMPLPESNDGARHVFSTNQENFLMDGKPVKIISGEMHYPRVPRQHWKDRFQRIKAMGMNTV
CTYLFWNVHEPEPGKWDFSGNLDFVEFIKEAQKAGLWVIVRPGPYVCAEWEFGGFPGWLLKDEDLKVRSQDPRFLEPAMA
YLKKVCSMLEPLQITKGGPIIMAQVENEYGSYGSDKDYVKKHLDVIRKELPGVVPFTSDGPNDWMIKNGTLPGVVPAMNF
GGGAKGAFANLEKHKGKTPRINGEFWVGWFDHWGKPKNGGSTEGFNRDLKWMLENNVSPNLFMAHGGTSFGFMNGANWEG
AYTPDVTNYDYGAPISENGTLTDRYRTFRQTIQDYYGDTYKLPEPPAQPEMMELPPITFTETAGMFSRLPQPVIRKEPVH
MEALGQSLGFILYRTKVNGPVKGELKMNNMQDRAIVYVDGKRQGAADRRYKQDSCDIVIPSGLHTVDIFVENMGRINFGG
QIQGERKGIRGPITLDGKKLENFLIYNFPCKGVELIPFSGKKPAGDQPVFHRGYFNVSNPKDTYLDMRDGWKKGVVWVNG
RNLGRFWFIGSQQALYCPGEYLKPGKNEIVVLDVDGGSGTVKGVKEAIYEVNRDPAMADVFRVGKPVAPAAGQLVHKGSF
AKGADQQEIKFRAPVQARYIAIVSKNAHDNGPHAAIAELNFLDASGNLLPREQWSVVYADSHETTGEAAQAGLVMDNQPT
TYWHTKWQGDNPRHPHMIVLDLGKVQKLSGFRYLPRQDRENGRIKDYEVYASPKPFKPAK
>Mature_780_residues
MKLSFFSVLLLAGHLCAAAPMPLPESNDGARHVFSTNQENFLMDGKPVKIISGEMHYPRVPRQHWKDRFQRIKAMGMNTV
CTYLFWNVHEPEPGKWDFSGNLDFVEFIKEAQKAGLWVIVRPGPYVCAEWEFGGFPGWLLKDEDLKVRSQDPRFLEPAMA
YLKKVCSMLEPLQITKGGPIIMAQVENEYGSYGSDKDYVKKHLDVIRKELPGVVPFTSDGPNDWMIKNGTLPGVVPAMNF
GGGAKGAFANLEKHKGKTPRINGEFWVGWFDHWGKPKNGGSTEGFNRDLKWMLENNVSPNLFMAHGGTSFGFMNGANWEG
AYTPDVTNYDYGAPISENGTLTDRYRTFRQTIQDYYGDTYKLPEPPAQPEMMELPPITFTETAGMFSRLPQPVIRKEPVH
MEALGQSLGFILYRTKVNGPVKGELKMNNMQDRAIVYVDGKRQGAADRRYKQDSCDIVIPSGLHTVDIFVENMGRINFGG
QIQGERKGIRGPITLDGKKLENFLIYNFPCKGVELIPFSGKKPAGDQPVFHRGYFNVSNPKDTYLDMRDGWKKGVVWVNG
RNLGRFWFIGSQQALYCPGEYLKPGKNEIVVLDVDGGSGTVKGVKEAIYEVNRDPAMADVFRVGKPVAPAAGQLVHKGSF
AKGADQQEIKFRAPVQARYIAIVSKNAHDNGPHAAIAELNFLDASGNLLPREQWSVVYADSHETTGEAAQAGLVMDNQPT
TYWHTKWQGDNPRHPHMIVLDLGKVQKLSGFRYLPRQDRENGRIKDYEVYASPKPFKPAK

Specific function: Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages [H]

COG id: COG1874

COG function: function code G; Beta-galactosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 35 family [H]

Homologues:

Organism=Homo sapiens, GI164519026, Length=572, Percent_Identity=37.5874125874126, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI31543093, Length=578, Percent_Identity=37.8892733564014, Blast_Score=375, Evalue=1e-103,
Organism=Homo sapiens, GI119372312, Length=631, Percent_Identity=36.7670364500792, Blast_Score=358, Evalue=8e-99,
Organism=Homo sapiens, GI119372308, Length=630, Percent_Identity=36.6666666666667, Blast_Score=357, Evalue=2e-98,
Organism=Homo sapiens, GI40255043, Length=593, Percent_Identity=36.9308600337268, Blast_Score=337, Evalue=2e-92,
Organism=Homo sapiens, GI208022658, Length=422, Percent_Identity=32.4644549763033, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI72000600, Length=617, Percent_Identity=33.7115072933549, Blast_Score=310, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI17568491, Length=601, Percent_Identity=30.7820299500832, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24646169, Length=595, Percent_Identity=34.9579831932773, Blast_Score=311, Evalue=8e-85,
Organism=Drosophila melanogaster, GI24582088, Length=639, Percent_Identity=32.5508607198748, Blast_Score=305, Evalue=6e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR019801
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR001944 [H]

Pfam domain/function: PF01301 Glyco_hydro_35 [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 87529; Mature: 87529

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50022 FA58C_3 ; PS01182 GLYCOSYL_HYDROL_F35

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSFFSVLLLAGHLCAAAPMPLPESNDGARHVFSTNQENFLMDGKPVKIISGEMHYPRV
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCEEECCCCEEEEECCCCCCCC
PRQHWKDRFQRIKAMGMNTVCTYLFWNVHEPEPGKWDFSGNLDFVEFIKEAQKAGLWVIV
CHHHHHHHHHHHHHCCHHHEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEE
RPGPYVCAEWEFGGFPGWLLKDEDLKVRSQDPRFLEPAMAYLKKVCSMLEPLQITKGGPI
CCCCCEEEECCCCCCCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHHHCCEEECCCCCE
IMAQVENEYGSYGSDKDYVKKHLDVIRKELPGVVPFTSDGPNDWMIKNGTLPGVVPAMNF
EEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCCCCCC
GGGAKGAFANLEKHKGKTPRINGEFWVGWFDHWGKPKNGGSTEGFNRDLKWMLENNVSPN
CCCCCCHHHHHHHHCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCC
LFMAHGGTSFGFMNGANWEGAYTPDVTNYDYGAPISENGTLTDRYRTFRQTIQDYYGDTY
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCE
KLPEPPAQPEMMELPPITFTETAGMFSRLPQPVIRKEPVHMEALGQSLGFILYRTKVNGP
ECCCCCCCCCCEECCCCEEEHHHHHHHHCCCHHHHCCCCHHHHHHHCCCEEEEEEECCCC
VKGELKMNNMQDRAIVYVDGKRQGAADRRYKQDSCDIVIPSGLHTVDIFVENMGRINFGG
EEEEEEECCCCCEEEEEECCCCCCCHHHCCCCCCCCEEECCCCEEEEEEECCCCCCCCCC
QIQGERKGIRGPITLDGKKLENFLIYNFPCKGVELIPFSGKKPAGDQPVFHRGYFNVSNP
EECCCCCCCCCCEEECCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEECCEEECCCC
KDTYLDMRDGWKKGVVWVNGRNLGRFWFIGSQQALYCPGEYLKPGKNEIVVLDVDGGSGT
CCCEEECCCCCCCCEEEECCCCCEEEEEECCCCEEECCHHHCCCCCCEEEEEEECCCCCC
VKGVKEAIYEVNRDPAMADVFRVGKPVAPAAGQLVHKGSFAKGADQQEIKFRAPVQARYI
HHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHEECCCCCCCCCCCCEEEECCCCEEEE
AIVSKNAHDNGPHAAIAELNFLDASGNLLPREQWSVVYADSHETTGEAAQAGLVMDNQPT
EEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHCCEEECCCCC
TYWHTKWQGDNPRHPHMIVLDLGKVQKLSGFRYLPRQDRENGRIKDYEVYASPKPFKPAK
EEEEEEECCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MKLSFFSVLLLAGHLCAAAPMPLPESNDGARHVFSTNQENFLMDGKPVKIISGEMHYPRV
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCEEECCCCEEEEECCCCCCCC
PRQHWKDRFQRIKAMGMNTVCTYLFWNVHEPEPGKWDFSGNLDFVEFIKEAQKAGLWVIV
CHHHHHHHHHHHHHCCHHHEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEE
RPGPYVCAEWEFGGFPGWLLKDEDLKVRSQDPRFLEPAMAYLKKVCSMLEPLQITKGGPI
CCCCCEEEECCCCCCCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHHHCCEEECCCCCE
IMAQVENEYGSYGSDKDYVKKHLDVIRKELPGVVPFTSDGPNDWMIKNGTLPGVVPAMNF
EEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCCCCCC
GGGAKGAFANLEKHKGKTPRINGEFWVGWFDHWGKPKNGGSTEGFNRDLKWMLENNVSPN
CCCCCCHHHHHHHHCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCC
LFMAHGGTSFGFMNGANWEGAYTPDVTNYDYGAPISENGTLTDRYRTFRQTIQDYYGDTY
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCE
KLPEPPAQPEMMELPPITFTETAGMFSRLPQPVIRKEPVHMEALGQSLGFILYRTKVNGP
ECCCCCCCCCCEECCCCEEEHHHHHHHHCCCHHHHCCCCHHHHHHHCCCEEEEEEECCCC
VKGELKMNNMQDRAIVYVDGKRQGAADRRYKQDSCDIVIPSGLHTVDIFVENMGRINFGG
EEEEEEECCCCCEEEEEECCCCCCCHHHCCCCCCCCEEECCCCEEEEEEECCCCCCCCCC
QIQGERKGIRGPITLDGKKLENFLIYNFPCKGVELIPFSGKKPAGDQPVFHRGYFNVSNP
EECCCCCCCCCCEEECCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEECCEEECCCC
KDTYLDMRDGWKKGVVWVNGRNLGRFWFIGSQQALYCPGEYLKPGKNEIVVLDVDGGSGT
CCCEEECCCCCCCCEEEECCCCCEEEEEECCCCEEECCHHHCCCCCCEEEEEEECCCCCC
VKGVKEAIYEVNRDPAMADVFRVGKPVAPAAGQLVHKGSFAKGADQQEIKFRAPVQARYI
HHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHEECCCCCCCCCCCCEEEECCCCEEEE
AIVSKNAHDNGPHAAIAELNFLDASGNLLPREQWSVVYADSHETTGEAAQAGLVMDNQPT
EEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHCCEEECCCCC
TYWHTKWQGDNPRHPHMIVLDLGKVQKLSGFRYLPRQDRENGRIKDYEVYASPKPFKPAK
EEEEEEECCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8563148 [H]