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The map label for this gene is yghZ [H]

Identifier: 187736017

GI number: 187736017

Start: 1826814

End: 1827803

Strand: Direct

Name: yghZ [H]

Synonym: Amuc_1527

Alternate gene names: 187736017

Gene position: 1826814-1827803 (Clockwise)

Preceding gene: 187736016

Following gene: 187736018

Centisome position: 68.57

GC content: 58.18

Gene sequence:

>990_bases
ATGAATTATCTTCCAGATCCCGGCCGCTATAGCCACGCAGCCTACCGCCGCTGCGGGCGCAGCGGGCTGCTGCTTCCTCC
CGTTTCCTTGGGGCTTTGGCATAATTTTGGCGCTGCGGATGATTTTGAGAACGCCCGTCGGCTTATTCACGGCGCGTTTG
ATGCCGGTATCACGTATTTTGACCTGGCGAATAATTACGGACCTCCTCCCGGTTCGGCGGAAGAATGCTTTGGCCGTATT
TTCATGCAGGATTTGTCCCGTTTCCGTGATGAACTTGTTATTGCAACCAAGGCGGGGCATCTGATGTGGCCCGGCCCGTA
TGGGGATTGGGGATCCCGCAAACACATGCTTGCCAGCCTGGACCAGTCCCTTTCCCGCATGAAGCTGGATTATGTGGATA
TTTTCTACGCGCACCGGCATGATCCGGAAACTCCCCTTGAAGAAACGGCGGGAGCCCTTGTTACGGCGGTTCGCTCCGGA
AAGGCCCTGTATGCCGGTATTTCCAAGTTCCCGGCGGAACAGGCCAGGCAGATGTGCTCCATGCTTGGGGAGGCCGGCGT
TCCGTGCCTGGTGCATCAGATCCGGTACAATATGTTTAATCGGGAACCGGAGAAATCCGTTTTTCAGGCTGTTCGGGAAA
CGGGTACCGGGTGCGCCGCTTTCTCTCCCCTGGCCCAGGGGATGTTGACGGACCGTTATCTGGAAGGCATTCCCGAAGAT
TCCCGCGCGGCGGGTTCCTCCGTCTTTTTAACAAAGGAGCGGGTTCTTCAGCATGGGGATAAAATTCGCCGCCTGGCCGC
CCTGGCCCGGAGCCGGGGCCAGAGCCTTGCCCAGATGGCTCTGGCCTGGGTGCTGAAAGATCCCGTAGTGACCACGGCCC
TGATTGGAGCCAGCCGCCCCTCGCAAATCAGGGATTGCCTGAAAGCACTGGATAGTGCGCCGTTTACGCCGGAGGAGCTC
TCTCTGATTGACGCAGATGCGGATAGATAG

Upstream 100 bases:

>100_bases
AACTGCTGGCTTCCAAATACCGTACGGAAGCATGGCGTTCCGGCGTACGGCATGGGCGTCCGTCTCAGCCACGGTAATTC
CCCCCCCTTTTTTCTTTCCG

Downstream 100 bases:

>100_bases
GCGCTGTTTTTCCCGTGGTGCTGGTCTTTCTGCTGGAAGGGGCATTTCCTGTTCCGGACACAGGTTTTTTCTTGGAGTAA
AGTAGAGCTGGTGTTATGTT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNYLPDPGRYSHAAYRRCGRSGLLLPPVSLGLWHNFGAADDFENARRLIHGAFDAGITYFDLANNYGPPPGSAEECFGRI
FMQDLSRFRDELVIATKAGHLMWPGPYGDWGSRKHMLASLDQSLSRMKLDYVDIFYAHRHDPETPLEETAGALVTAVRSG
KALYAGISKFPAEQARQMCSMLGEAGVPCLVHQIRYNMFNREPEKSVFQAVRETGTGCAAFSPLAQGMLTDRYLEGIPED
SRAAGSSVFLTKERVLQHGDKIRRLAALARSRGQSLAQMALAWVLKDPVVTTALIGASRPSQIRDCLKALDSAPFTPEEL
SLIDADADR

Sequences:

>Translated_329_residues
MNYLPDPGRYSHAAYRRCGRSGLLLPPVSLGLWHNFGAADDFENARRLIHGAFDAGITYFDLANNYGPPPGSAEECFGRI
FMQDLSRFRDELVIATKAGHLMWPGPYGDWGSRKHMLASLDQSLSRMKLDYVDIFYAHRHDPETPLEETAGALVTAVRSG
KALYAGISKFPAEQARQMCSMLGEAGVPCLVHQIRYNMFNREPEKSVFQAVRETGTGCAAFSPLAQGMLTDRYLEGIPED
SRAAGSSVFLTKERVLQHGDKIRRLAALARSRGQSLAQMALAWVLKDPVVTTALIGASRPSQIRDCLKALDSAPFTPEEL
SLIDADADR
>Mature_329_residues
MNYLPDPGRYSHAAYRRCGRSGLLLPPVSLGLWHNFGAADDFENARRLIHGAFDAGITYFDLANNYGPPPGSAEECFGRI
FMQDLSRFRDELVIATKAGHLMWPGPYGDWGSRKHMLASLDQSLSRMKLDYVDIFYAHRHDPETPLEETAGALVTAVRSG
KALYAGISKFPAEQARQMCSMLGEAGVPCLVHQIRYNMFNREPEKSVFQAVRETGTGCAAFSPLAQGMLTDRYLEGIPED
SRAAGSSVFLTKERVLQHGDKIRRLAALARSRGQSLAQMALAWVLKDPVVTTALIGASRPSQIRDCLKALDSAPFTPEEL
SLIDADADR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436962, Length=321, Percent_Identity=34.5794392523364, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI27436964, Length=320, Percent_Identity=34.375, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI27436969, Length=309, Percent_Identity=34.9514563106796, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI27436966, Length=320, Percent_Identity=34.0625, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=34.9514563106796, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=32.4159021406728, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI41152114, Length=223, Percent_Identity=26.457399103139, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI41327764, Length=225, Percent_Identity=27.1111111111111, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI223718702, Length=225, Percent_Identity=25.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=54.4072948328268, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI87081735, Length=285, Percent_Identity=35.7894736842105, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789199, Length=330, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788070, Length=330, Percent_Identity=26.3636363636364, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=24.4047619047619, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=303, Percent_Identity=25.7425742574257, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=324, Percent_Identity=26.2345679012346, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=327, Percent_Identity=25.3822629969419, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=253, Percent_Identity=25.6916996047431, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640980, Length=338, Percent_Identity=28.9940828402367, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI45549126, Length=336, Percent_Identity=28.2738095238095, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24646155, Length=314, Percent_Identity=26.4331210191083, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646159, Length=317, Percent_Identity=24.9211356466877, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 36280; Mature: 36280

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYLPDPGRYSHAAYRRCGRSGLLLPPVSLGLWHNFGAADDFENARRLIHGAFDAGITYF
CCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHE
DLANNYGPPPGSAEECFGRIFMQDLSRFRDELVIATKAGHLMWPGPYGDWGSRKHMLASL
EHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCEECCCCCCCCCCHHHHHHHH
DQSLSRMKLDYVDIFYAHRHDPETPLEETAGALVTAVRSGKALYAGISKFPAEQARQMCS
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHH
MLGEAGVPCLVHQIRYNMFNREPEKSVFQAVRETGTGCAAFSPLAQGMLTDRYLEGIPED
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
SRAAGSSVFLTKERVLQHGDKIRRLAALARSRGQSLAQMALAWVLKDPVVTTALIGASRP
HHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCC
SQIRDCLKALDSAPFTPEELSLIDADADR
HHHHHHHHHHHCCCCCHHHHHEECCCCCC
>Mature Secondary Structure
MNYLPDPGRYSHAAYRRCGRSGLLLPPVSLGLWHNFGAADDFENARRLIHGAFDAGITYF
CCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHE
DLANNYGPPPGSAEECFGRIFMQDLSRFRDELVIATKAGHLMWPGPYGDWGSRKHMLASL
EHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCEECCCCCCCCCCHHHHHHHH
DQSLSRMKLDYVDIFYAHRHDPETPLEETAGALVTAVRSGKALYAGISKFPAEQARQMCS
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHH
MLGEAGVPCLVHQIRYNMFNREPEKSVFQAVRETGTGCAAFSPLAQGMLTDRYLEGIPED
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
SRAAGSSVFLTKERVLQHGDKIRRLAALARSRGQSLAQMALAWVLKDPVVTTALIGASRP
HHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCC
SQIRDCLKALDSAPFTPEELSLIDADADR
HHHHHHHHHHHCCCCCHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]