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The map label for this gene is ruvA [H]

Identifier: 187735908

GI number: 187735908

Start: 1694530

End: 1695192

Strand: Direct

Name: ruvA [H]

Synonym: Amuc_1416

Alternate gene names: 187735908

Gene position: 1694530-1695192 (Clockwise)

Preceding gene: 187735907

Following gene: 187735909

Centisome position: 63.61

GC content: 59.28

Gene sequence:

>663_bases
ATGACGGAAGCGGTTCCGGAGGATGCGTTTTTAGCTTGCGCGCGGGCCGGATTGTGTCACGTTAAGGGTATGATAGCTTT
TCTGCGCGGCACGGTGGCGGAATCATATCCCCAGCGGTTGATCCTGGATGTTCATGGGGTGGGGTATGAAGTGATTGTGC
CCCTGTCCACGTTTGACAGGCTGAATCCCCTTCCCGGCAGAGAGCTGACGCTGAAAACCTACCTGCATGTCCGGGAGAAC
ATGCAGGTGCTGTACGGTTTTGCCACGGATGCGGAAAGGGATATTTTCCTGCTGCTGATTGAACGTGTTTCCGGAATCGG
CCCGGCAACGGCGATTGCCATTTTGGGTTCCCTGTCCGTGGAGCAGTTCAAGCAGGCGGTTGTGGGCGGAGATGTTTCCG
GCATTGCTCGGGCCAAGGGGGTGGGCAAGAAGACGGCGGAACGCATCGTCCTGGAACTGAAGGATAAAGTGGGCCTGGCC
GCCACGTGGGAAGCCCAGGCCCAGGGCGCTACTTCCCAGGCCGCCGGGGACGCGGAATTGGCGCTGATTGCGCTCGGGTT
CAAGCAGGTGGAATCCCGCAAGGCGATAGCCGCCCATCTGAAGGACCATCCGGATGCAGACGTGGACGAGCTCATACGCG
CCGCTTTGCGTTCCATGAATTGA

Upstream 100 bases:

>100_bases
AATACAGGTGCAGGATGAAAACAGCCCGTGGACTGCGCGTGCGCTGCTTTTACCACCGGGAGGATCTGGAACATGTCAGG
CTGCACGTGCTCCAGAAAAG

Downstream 100 bases:

>100_bases
AGGAGCTTCCGGAGGAAGGAAGGTGTTTTTGCAAGTTTTTGATTTTCATGAGGGAACATGTCCGCCTGGCGGAGTGTTCC
CTGTTTGCGGAAGCTGGGGG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTEAVPEDAFLACARAGLCHVKGMIAFLRGTVAESYPQRLILDVHGVGYEVIVPLSTFDRLNPLPGRELTLKTYLHVREN
MQVLYGFATDAERDIFLLLIERVSGIGPATAIAILGSLSVEQFKQAVVGGDVSGIARAKGVGKKTAERIVLELKDKVGLA
ATWEAQAQGATSQAAGDAELALIALGFKQVESRKAIAAHLKDHPDADVDELIRAALRSMN

Sequences:

>Translated_220_residues
MTEAVPEDAFLACARAGLCHVKGMIAFLRGTVAESYPQRLILDVHGVGYEVIVPLSTFDRLNPLPGRELTLKTYLHVREN
MQVLYGFATDAERDIFLLLIERVSGIGPATAIAILGSLSVEQFKQAVVGGDVSGIARAKGVGKKTAERIVLELKDKVGLA
ATWEAQAQGATSQAAGDAELALIALGFKQVESRKAIAAHLKDHPDADVDELIRAALRSMN
>Mature_219_residues
TEAVPEDAFLACARAGLCHVKGMIAFLRGTVAESYPQRLILDVHGVGYEVIVPLSTFDRLNPLPGRELTLKTYLHVRENM
QVLYGFATDAERDIFLLLIERVSGIGPATAIAILGSLSVEQFKQAVVGGDVSGIARAKGVGKKTAERIVLELKDKVGLAA
TWEAQAQGATSQAAGDAELALIALGFKQVESRKAIAAHLKDHPDADVDELIRAALRSMN

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=39.5121951219512, Blast_Score=130, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 23560; Mature: 23428

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAVPEDAFLACARAGLCHVKGMIAFLRGTVAESYPQRLILDVHGVGYEVIVPLSTFDR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCEEEEEECHHHHH
LNPLPGRELTLKTYLHVRENMQVLYGFATDAERDIFLLLIERVSGIGPATAIAILGSLSV
CCCCCCCCEEHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCH
EQFKQAVVGGDVSGIARAKGVGKKTAERIVLELKDKVGLAATWEAQAQGATSQAAGDAEL
HHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCHHHCCCCCCCCCCCCE
ALIALGFKQVESRKAIAAHLKDHPDADVDELIRAALRSMN
EHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TEAVPEDAFLACARAGLCHVKGMIAFLRGTVAESYPQRLILDVHGVGYEVIVPLSTFDR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCEEEEEECHHHHH
LNPLPGRELTLKTYLHVRENMQVLYGFATDAERDIFLLLIERVSGIGPATAIAILGSLSV
CCCCCCCCEEHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCH
EQFKQAVVGGDVSGIARAKGVGKKTAERIVLELKDKVGLAATWEAQAQGATSQAAGDAEL
HHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCHHHCCCCCCCCCCCCE
ALIALGFKQVESRKAIAAHLKDHPDADVDELIRAALRSMN
EHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA