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The map label for this gene is dinB

Identifier: 187735823

GI number: 187735823

Start: 1606901

End: 1607980

Strand: Reverse

Name: dinB

Synonym: Amuc_1330

Alternate gene names: 187735823

Gene position: 1607980-1606901 (Counterclockwise)

Preceding gene: 187735846

Following gene: 187735822

Centisome position: 60.36

GC content: 58.98

Gene sequence:

>1080_bases
ATGAACCAGAGAAAAATCATCCATGTGGATATGGATGCCTTTTACGCATCCATAGAACAGCGGGACCATCCCGAATACCG
CGGCAAGCCCATCGCCGTAGGCAGGCCGGAAATGCGCGGCGTGGTGGCGGCGGCCAGTTATGAGGCGCGCCGTTTCGGAG
TGCGTTCCGCCATGCCTTCCATGAAGGCTCTCAAGCTTTGCCCCCATCTGATTTTCACCCGCAACCGCATGGATGTGTAC
AAGGCCGTCTCCGCGCAGATACACGCCATTTTCCACCGTTACACAGATCTGGTGGAACCCCTTTCCCTGGATGAAGCCTT
TCTGGACGTCACGGAAAACAAGCCGGGCATTCCGCTGGCCGTCGACATTGCGAGGAGGATTAAGAAGGAAATCCGCCGGG
AACTTCACCTGACGGCCTCCGCCGGCGTTTCCTACAATAAATTCCTGGCAAAAATCGCTTCCGATTACCGTAAGCCGGAC
GGGCTGTTCACGATCCATCCATCCCGGGCGGAAAAATTCATCGCGGCACTTCCCATTGAAGCTTTCTGGGGAGTCGGGCA
CGCCACCGCCGAACGCATGCGCGCCCTTTCCATCACCAACGGGGCGCAGCTCCGGGCACGGGACAAAGACTTCCTGGTAA
GGCATTTCGGCAAAACAGGAGCCATCTTCTACAACTTCGCCCGCGGTGTGGACGACCGCCCTGTGGAACCTTCCCGCATG
CGCAAATCCGTGGGTTGTGAAGAAACCTACCGGGAAAACGTCACCAGGGCGGAAGCGCTGGAACAACGCCTCCCCCTGCT
GGCGGAAGAACTCGCGGGGCGGCTGGCCCGTTCCGGCTTCCGGGGAAACACCCTTACCCTGAAGGTTAAGTTCCCGGACT
TTGTCCAGAAGACCCGCTGCGCGACCGTTCCGGAAATCCTGACGGAGAAAGAAGGAATTCTCCCCCTGGCCCGCACCCTG
ATGGAAGAACTGGATTCCGGGGACCGTACATTCCGCCTTCTGGGGCTGTCCGTCTCCCATCCCCAGGAAGAACAGCGGCA
GGGCATCTGGGAACAGCTCTGGCTGGAGCTGGAGTATTAA

Upstream 100 bases:

>100_bases
AGCTTTTCCTTCCAACTGGACTTGCAGGATAAGTCGGATTATGATGGGGCATCCCATTCCCTCATGTTTCCCGCCCCATC
AGGAATCATGAAGCGCTCCC

Downstream 100 bases:

>100_bases
CTCTTCCATAGACTGCCATATTTTCAGGACTCTCCCCTTAAAAACGGCAATACCCACAAGATATCGTTTCAGGAATGAGC
AAAACCCGCTCCAACCTGGT

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MNQRKIIHVDMDAFYASIEQRDHPEYRGKPIAVGRPEMRGVVAAASYEARRFGVRSAMPSMKALKLCPHLIFTRNRMDVY
KAVSAQIHAIFHRYTDLVEPLSLDEAFLDVTENKPGIPLAVDIARRIKKEIRRELHLTASAGVSYNKFLAKIASDYRKPD
GLFTIHPSRAEKFIAALPIEAFWGVGHATAERMRALSITNGAQLRARDKDFLVRHFGKTGAIFYNFARGVDDRPVEPSRM
RKSVGCEETYRENVTRAEALEQRLPLLAEELAGRLARSGFRGNTLTLKVKFPDFVQKTRCATVPEILTEKEGILPLARTL
MEELDSGDRTFRLLGLSVSHPQEEQRQGIWEQLWLELEY

Sequences:

>Translated_359_residues
MNQRKIIHVDMDAFYASIEQRDHPEYRGKPIAVGRPEMRGVVAAASYEARRFGVRSAMPSMKALKLCPHLIFTRNRMDVY
KAVSAQIHAIFHRYTDLVEPLSLDEAFLDVTENKPGIPLAVDIARRIKKEIRRELHLTASAGVSYNKFLAKIASDYRKPD
GLFTIHPSRAEKFIAALPIEAFWGVGHATAERMRALSITNGAQLRARDKDFLVRHFGKTGAIFYNFARGVDDRPVEPSRM
RKSVGCEETYRENVTRAEALEQRLPLLAEELAGRLARSGFRGNTLTLKVKFPDFVQKTRCATVPEILTEKEGILPLARTL
MEELDSGDRTFRLLGLSVSHPQEEQRQGIWEQLWLELEY
>Mature_359_residues
MNQRKIIHVDMDAFYASIEQRDHPEYRGKPIAVGRPEMRGVVAAASYEARRFGVRSAMPSMKALKLCPHLIFTRNRMDVY
KAVSAQIHAIFHRYTDLVEPLSLDEAFLDVTENKPGIPLAVDIARRIKKEIRRELHLTASAGVSYNKFLAKIASDYRKPD
GLFTIHPSRAEKFIAALPIEAFWGVGHATAERMRALSITNGAQLRARDKDFLVRHFGKTGAIFYNFARGVDDRPVEPSRM
RKSVGCEETYRENVTRAEALEQRLPLLAEELAGRLARSGFRGNTLTLKVKFPDFVQKTRCATVPEILTEKEGILPLARTL
MEELDSGDRTFRLLGLSVSHPQEEQRQGIWEQLWLELEY

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI84043967, Length=342, Percent_Identity=31.2865497076023, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI7706681, Length=343, Percent_Identity=31.1953352769679, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI154350220, Length=324, Percent_Identity=27.4691358024691, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI5729982, Length=349, Percent_Identity=27.5071633237822, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=48.5981308411215, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1786425, Length=350, Percent_Identity=44, Blast_Score=257, Evalue=7e-70,
Organism=Escherichia coli, GI1787432, Length=280, Percent_Identity=27.1428571428571, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI193205700, Length=417, Percent_Identity=28.0575539568345, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17537959, Length=304, Percent_Identity=27.6315789473684, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI193205702, Length=363, Percent_Identity=25.6198347107438, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115534089, Length=123, Percent_Identity=35.7723577235772, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=207, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355641, Length=316, Percent_Identity=29.746835443038, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24644984, Length=316, Percent_Identity=29.746835443038, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI19923006, Length=340, Percent_Identity=26.1764705882353, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24668444, Length=118, Percent_Identity=36.4406779661017, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_AKKM8 (B2UKN1)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001877935.1
- ProteinModelPortal:   B2UKN1
- SMR:   B2UKN1
- GeneID:   6275839
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_1330
- HOGENOM:   HBG734504
- OMA:   HRIFRRY
- ProtClustDB:   CLSK823933
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 40892; Mature: 40892

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 105-105

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRKIIHVDMDAFYASIEQRDHPEYRGKPIAVGRPEMRGVVAAASYEARRFGVRSAMPS
CCCCEEEEEEHHHHHHHHHHCCCCCCCCCCEECCCCHHHHEEHHHHHHHHHHHHHHHCCH
MKALKLCPHLIFTRNRMDVYKAVSAQIHAIFHRYTDLVEPLSLDEAFLDVTENKPGIPLA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHH
VDIARRIKKEIRRELHLTASAGVSYNKFLAKIASDYRKPDGLFTIHPSRAEKFIAALPIE
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHH
AFWGVGHATAERMRALSITNGAQLRARDKDFLVRHFGKTGAIFYNFARGVDDRPVEPSRM
HHHCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHH
RKSVGCEETYRENVTRAEALEQRLPLLAEELAGRLARSGFRGNTLTLKVKFPDFVQKTRC
HHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHH
ATVPEILTEKEGILPLARTLMEELDSGDRTFRLLGLSVSHPQEEQRQGIWEQLWLELEY
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHCCHHHHHHEECCC
>Mature Secondary Structure
MNQRKIIHVDMDAFYASIEQRDHPEYRGKPIAVGRPEMRGVVAAASYEARRFGVRSAMPS
CCCCEEEEEEHHHHHHHHHHCCCCCCCCCCEECCCCHHHHEEHHHHHHHHHHHHHHHCCH
MKALKLCPHLIFTRNRMDVYKAVSAQIHAIFHRYTDLVEPLSLDEAFLDVTENKPGIPLA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHH
VDIARRIKKEIRRELHLTASAGVSYNKFLAKIASDYRKPDGLFTIHPSRAEKFIAALPIE
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHH
AFWGVGHATAERMRALSITNGAQLRARDKDFLVRHFGKTGAIFYNFARGVDDRPVEPSRM
HHHCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHH
RKSVGCEETYRENVTRAEALEQRLPLLAEELAGRLARSGFRGNTLTLKVKFPDFVQKTRC
HHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHH
ATVPEILTEKEGILPLARTLMEELDSGDRTFRLLGLSVSHPQEEQRQGIWEQLWLELEY
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHCCHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA