Definition | Akkermansia muciniphila ATCC BAA-835, complete genome. |
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Accession | NC_010655 |
Length | 2,664,102 |
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The map label for this gene is pqqL [C]
Identifier: 187735805
GI number: 187735805
Start: 1589705
End: 1592227
Strand: Direct
Name: pqqL [C]
Synonym: Amuc_1312
Alternate gene names: 187735805
Gene position: 1589705-1592227 (Clockwise)
Preceding gene: 187735801
Following gene: 187735806
Centisome position: 59.67
GC content: 59.33
Gene sequence:
>2523_bases ATGAGTTCAGCCAAGGAACCTGTGACGCGCCGTTTTGGAAATGGTTTGACGGTTTTGATTAAGGAGGACAAGTCTCATCC CGTAGTGTCCCTCCAGTACTGGGTAGGCACGGGGTCCATGAATGAGGGGCACTGGCAGGGGAGCGGACTTTCCCATTTGC TGGAGCATCTGGTGTTTAAGGGAACGGCGCATTTCTCCGGGCAGGAACTGGCCCGCAAGGTGCAGGAACGCGGCGGCCAC TGGAATGCGTACACCAGCGTGAACCGCACCGTGTACTATATAGACGGCCCTGCGGAGTCCTGGCAGATTTTCCTGAATCT TCTGACGGAGCTTGTATTTTTCCCCACGTTCCCGGAAGACGAGATGGAGCGGGAGAAGGAGGTCGTGCGCCGGGAGATGG CCATGTATGCGGATGATCCCGATTCCGTGGCCTACCAGCTTCTGATGCAGACGCTGTATCTCAAGCATCCCCGCCGCTGG CCCGTTCTGGGTGAGCGCGCCGCCTTTGACTGCCTGACGCGGCAGGACGTGCTGGATTACCATGCCAGCCGTTATGTTCC GAACAACGTGGTTCTTTCCATCGCGGGGGACGTGGATGCCGCGGAGATTCTTTCCCATCTGGAATTGCTGGTGGAAGACC TGAAATCCCGTCCCCTGAACCGGGAACCCATTCCCCATGAACCTCACCAGTTCGGTTCCCGCAGGGTGCGGAAGGAGTTT GCCGTGCCTTACTCCAAGCTGCACCTTGCCTGGCGCCTGCCCTGTTCCGCCCATCCGGATACGCCAGCCCTTTCCGCTCT GTCCAGCATTCTGGGAGGCGGACGTTCCGCCCGTTTTTATGAAAAATTCCATGACCGCCTGGGCCTGGTGTACAGCATTG AGGTGCATTCCAACCAGTCTGAGACGGATGAAGGGGCGTTTACCATCAGCATGGACGTGGACCGCGCCCAGCGCGACAAG GTGCGGGACCTGGTACTTCAGGAGCTTCGCAATCTGGCGGAAGAGGATTTTACGGAGGACCTGAAGAGAGTCTGCAAACA GACCCGGGTCAGTCGCCTGCGCCGCAGGAGTTCCGCTTCCGGGGTGGCCTCGGAAATGGGGGCGGATTGGTTCGGCTCGC GCAATTTGAACCTGTCTTCCGAATGGCAGGAAGCTATTGAACGGGTGACTACGGAAGATTTGCACCGCGTTTGTTCCACC TGGCTGTCTTCCCCGAATGTGACGGAAGTCAGCCTGGACCCCCCGGGCAGCAACGCCGGGGATGAAGAAAGGGCCTCCGC CTCTGCGGGAACGGCCCTGAGCGAGCATGTTCTTGGCAACGGCATGAAGGTGGTGATCCGTGAAGACCATCGCCTGCCGC TGGCCTATGCCTGCATGGCGTTCAAGGCCGGATGCCGTGCGGAGAATGAGCATGACGCCGGGGTGACGGACTTGATGTCC GAGTGCCTGCTGAAAGGAACCTCCACCCGTTCCGCGGCGGATATAGCCCGTTTTCTGGAGGACATCGGGGGAGCCATCAA CACGTCCACCGGTAACAATTCCCTGAGCGTGGGATGTCAGGTTCTGGCGGAAGACCTGGACGCCGGATTGGAGCTGATGG CGGATGTGGTCATGAATCCGTCTTTCCCGGAAGACGCCTTTCTGAGGGAAAAGGAATCTTTTGTGGCGGATGCGGAGGAG GATATGGAAGACCCTCTTTCCGTGGCGTTCCGGCAGGAGCGGAAGGTGGCTTACGGGCATGTTTCCTATGGAAATTCCCC TTCCGGCACGCCGGAAAGCCTGTCTTCACTGACGGTTCAGGACATCAAAAAACAGTATGAACGCATTATCTGCGCTTCCA ACGCCGTGATTTGCATTTCCGGAGATGTCAGGAAGGATGAGGTCCTGCCTCTTCTGGAAAAACATCTGGGAGGCATGAGG GCGGGAACGCCTCCGGCCCTGATTCCCACGCCCGCGCTGCGGGCCGGCCGGGAAGTGGCCGTGCTGGATAAACAGCAGGC CGTGCTGGTAGTGGGGGTGCCGGGCGTGGACGTGGCTTCCCCGGAGATGGCCCAGGCTCTGCTGTTCCAGTCCTGGTGCA GTGATATGGCCGGTCCCGTTTTCACCAATATCCGGGAGGAGGCCGGACTGGCCTATTATGCCAGTTCTTCCCTGTTCATC GGCATGGATGCCGGAGGCATCTGCTTCTATCTGGGCACTTCCCCGGAACAATTGGAGGAAGCCGGGCGGAGGCTGGAAAA AACACTGGAGATGATTGATGAACAGGGCATGACGGAGGAGGAGCTGGAACGCACCAGGGCGGCCGCCCTGTCTTCCCGTC TGCTGGCCATGCAGTCCAATGGAACTTTGTGCCAGATGCTGGCGCTGGATATCCTGTTCGGTCTGCCTCTGGAAGCGTTT GAACAGCAGACGGACGCTATCAGGAATATGGATCTGGCCCGGATGAACGCCTTTATCAGGAAGGTGCTGGATCCCGCCCA GCCGCGTTCCTGGTCCATCGTGCGTCCGCCTGCCGGGGAGTAA
Upstream 100 bases:
>100_bases TGAGGACGCGCTTTTAGCCTCCGGGGTAAGTTTGACAGTCCGGGGGCACGTACGGAGCGCCGGCTTGCATGGGGCGCCTT CTTGAGGCACGGTAGGGAAC
Downstream 100 bases:
>100_bases TTCCCCGGAAAATCATTTCCTTTTTCCCTGTCCGGGAAAAAGGCAGGATTAAATAAAAAGGAATATTTTTGCGTTACATC ATCTGAAGGCTGGGGGAGGG
Product: peptidase M16 domain protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 840; Mature: 839
Protein sequence:
>840_residues MSSAKEPVTRRFGNGLTVLIKEDKSHPVVSLQYWVGTGSMNEGHWQGSGLSHLLEHLVFKGTAHFSGQELARKVQERGGH WNAYTSVNRTVYYIDGPAESWQIFLNLLTELVFFPTFPEDEMEREKEVVRREMAMYADDPDSVAYQLLMQTLYLKHPRRW PVLGERAAFDCLTRQDVLDYHASRYVPNNVVLSIAGDVDAAEILSHLELLVEDLKSRPLNREPIPHEPHQFGSRRVRKEF AVPYSKLHLAWRLPCSAHPDTPALSALSSILGGGRSARFYEKFHDRLGLVYSIEVHSNQSETDEGAFTISMDVDRAQRDK VRDLVLQELRNLAEEDFTEDLKRVCKQTRVSRLRRRSSASGVASEMGADWFGSRNLNLSSEWQEAIERVTTEDLHRVCST WLSSPNVTEVSLDPPGSNAGDEERASASAGTALSEHVLGNGMKVVIREDHRLPLAYACMAFKAGCRAENEHDAGVTDLMS ECLLKGTSTRSAADIARFLEDIGGAINTSTGNNSLSVGCQVLAEDLDAGLELMADVVMNPSFPEDAFLREKESFVADAEE DMEDPLSVAFRQERKVAYGHVSYGNSPSGTPESLSSLTVQDIKKQYERIICASNAVICISGDVRKDEVLPLLEKHLGGMR AGTPPALIPTPALRAGREVAVLDKQQAVLVVGVPGVDVASPEMAQALLFQSWCSDMAGPVFTNIREEAGLAYYASSSLFI GMDAGGICFYLGTSPEQLEEAGRRLEKTLEMIDEQGMTEEELERTRAAALSSRLLAMQSNGTLCQMLALDILFGLPLEAF EQQTDAIRNMDLARMNAFIRKVLDPAQPRSWSIVRPPAGE
Sequences:
>Translated_840_residues MSSAKEPVTRRFGNGLTVLIKEDKSHPVVSLQYWVGTGSMNEGHWQGSGLSHLLEHLVFKGTAHFSGQELARKVQERGGH WNAYTSVNRTVYYIDGPAESWQIFLNLLTELVFFPTFPEDEMEREKEVVRREMAMYADDPDSVAYQLLMQTLYLKHPRRW PVLGERAAFDCLTRQDVLDYHASRYVPNNVVLSIAGDVDAAEILSHLELLVEDLKSRPLNREPIPHEPHQFGSRRVRKEF AVPYSKLHLAWRLPCSAHPDTPALSALSSILGGGRSARFYEKFHDRLGLVYSIEVHSNQSETDEGAFTISMDVDRAQRDK VRDLVLQELRNLAEEDFTEDLKRVCKQTRVSRLRRRSSASGVASEMGADWFGSRNLNLSSEWQEAIERVTTEDLHRVCST WLSSPNVTEVSLDPPGSNAGDEERASASAGTALSEHVLGNGMKVVIREDHRLPLAYACMAFKAGCRAENEHDAGVTDLMS ECLLKGTSTRSAADIARFLEDIGGAINTSTGNNSLSVGCQVLAEDLDAGLELMADVVMNPSFPEDAFLREKESFVADAEE DMEDPLSVAFRQERKVAYGHVSYGNSPSGTPESLSSLTVQDIKKQYERIICASNAVICISGDVRKDEVLPLLEKHLGGMR AGTPPALIPTPALRAGREVAVLDKQQAVLVVGVPGVDVASPEMAQALLFQSWCSDMAGPVFTNIREEAGLAYYASSSLFI GMDAGGICFYLGTSPEQLEEAGRRLEKTLEMIDEQGMTEEELERTRAAALSSRLLAMQSNGTLCQMLALDILFGLPLEAF EQQTDAIRNMDLARMNAFIRKVLDPAQPRSWSIVRPPAGE >Mature_839_residues SSAKEPVTRRFGNGLTVLIKEDKSHPVVSLQYWVGTGSMNEGHWQGSGLSHLLEHLVFKGTAHFSGQELARKVQERGGHW NAYTSVNRTVYYIDGPAESWQIFLNLLTELVFFPTFPEDEMEREKEVVRREMAMYADDPDSVAYQLLMQTLYLKHPRRWP VLGERAAFDCLTRQDVLDYHASRYVPNNVVLSIAGDVDAAEILSHLELLVEDLKSRPLNREPIPHEPHQFGSRRVRKEFA VPYSKLHLAWRLPCSAHPDTPALSALSSILGGGRSARFYEKFHDRLGLVYSIEVHSNQSETDEGAFTISMDVDRAQRDKV RDLVLQELRNLAEEDFTEDLKRVCKQTRVSRLRRRSSASGVASEMGADWFGSRNLNLSSEWQEAIERVTTEDLHRVCSTW LSSPNVTEVSLDPPGSNAGDEERASASAGTALSEHVLGNGMKVVIREDHRLPLAYACMAFKAGCRAENEHDAGVTDLMSE CLLKGTSTRSAADIARFLEDIGGAINTSTGNNSLSVGCQVLAEDLDAGLELMADVVMNPSFPEDAFLREKESFVADAEED MEDPLSVAFRQERKVAYGHVSYGNSPSGTPESLSSLTVQDIKKQYERIICASNAVICISGDVRKDEVLPLLEKHLGGMRA GTPPALIPTPALRAGREVAVLDKQQAVLVVGVPGVDVASPEMAQALLFQSWCSDMAGPVFTNIREEAGLAYYASSSLFIG MDAGGICFYLGTSPEQLEEAGRRLEKTLEMIDEQGMTEEELERTRAAALSSRLLAMQSNGTLCQMLALDILFGLPLEAFE QQTDAIRNMDLARMNAFIRKVLDPAQPRSWSIVRPPAGE
Specific function: Unknown
COG id: COG0612
COG function: function code R; Predicted Zn-dependent peptidases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase M16 family [H]
Homologues:
Organism=Homo sapiens, GI94538354, Length=401, Percent_Identity=24.9376558603491, Blast_Score=113, Evalue=1e-24, Organism=Homo sapiens, GI46593007, Length=263, Percent_Identity=28.8973384030418, Blast_Score=104, Evalue=3e-22, Organism=Escherichia coli, GI1787770, Length=227, Percent_Identity=26.431718061674, Blast_Score=69, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71999683, Length=403, Percent_Identity=22.3325062034739, Blast_Score=87, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17553678, Length=401, Percent_Identity=21.1970074812968, Blast_Score=67, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6323192, Length=278, Percent_Identity=27.6978417266187, Blast_Score=96, Evalue=2e-20, Organism=Saccharomyces cerevisiae, GI6321813, Length=412, Percent_Identity=24.5145631067961, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI21357875, Length=384, Percent_Identity=25.78125, Blast_Score=105, Evalue=2e-22, Organism=Drosophila melanogaster, GI24646943, Length=384, Percent_Identity=25.78125, Blast_Score=105, Evalue=2e-22,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011249 - InterPro: IPR011237 - InterPro: IPR011765 - InterPro: IPR001431 - InterPro: IPR007863 [H]
Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]
EC number: 3.4.99.- [C]
Molecular weight: Translated: 93012; Mature: 92881
Theoretical pI: Translated: 4.87; Mature: 4.87
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 4.4 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSSAKEPVTRRFGNGLTVLIKEDKSHPVVSLQYWVGTGSMNEGHWQGSGLSHLLEHLVFK CCCCCCHHHHHHCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH GTAHFSGQELARKVQERGGHWNAYTSVNRTVYYIDGPAESWQIFLNLLTELVFFPTFPED CCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHH EMEREKEVVRREMAMYADDPDSVAYQLLMQTLYLKHPRRWPVLGERAAFDCLTRQDVLDY HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH HASRYVPNNVVLSIAGDVDAAEILSHLELLVEDLKSRPLNREPIPHEPHQFGSRRVRKEF HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH AVPYSKLHLAWRLPCSAHPDTPALSALSSILGGGRSARFYEKFHDRLGLVYSIEVHSNQS CCCHHHEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEEEECCCC ETDEGAFTISMDVDRAQRDKVRDLVLQELRNLAEEDFTEDLKRVCKQTRVSRLRRRSSAS CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC GVASEMGADWFGSRNLNLSSEWQEAIERVTTEDLHRVCSTWLSSPNVTEVSLDPPGSNAG CHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC DEERASASAGTALSEHVLGNGMKVVIREDHRLPLAYACMAFKAGCRAENEHDAGVTDLMS CHHHHHHHHCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHH ECLLKGTSTRSAADIARFLEDIGGAINTSTGNNSLSVGCQVLAEDLDAGLELMADVVMNP HHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC SFPEDAFLREKESFVADAEEDMEDPLSVAFRQERKVAYGHVSYGNSPSGTPESLSSLTVQ CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH DIKKQYERIICASNAVICISGDVRKDEVLPLLEKHLGGMRAGTPPALIPTPALRAGREVA HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCEEE VLDKQQAVLVVGVPGVDVASPEMAQALLFQSWCSDMAGPVFTNIREEAGLAYYASSSLFI EECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCEEE GMDAGGICFYLGTSPEQLEEAGRRLEKTLEMIDEQGMTEEELERTRAAALSSRLLAMQSN EECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCC GTLCQMLALDILFGLPLEAFEQQTDAIRNMDLARMNAFIRKVLDPAQPRSWSIVRPPAGE CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCC >Mature Secondary Structure SSAKEPVTRRFGNGLTVLIKEDKSHPVVSLQYWVGTGSMNEGHWQGSGLSHLLEHLVFK CCCCCHHHHHHCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH GTAHFSGQELARKVQERGGHWNAYTSVNRTVYYIDGPAESWQIFLNLLTELVFFPTFPED CCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHH EMEREKEVVRREMAMYADDPDSVAYQLLMQTLYLKHPRRWPVLGERAAFDCLTRQDVLDY HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH HASRYVPNNVVLSIAGDVDAAEILSHLELLVEDLKSRPLNREPIPHEPHQFGSRRVRKEF HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH AVPYSKLHLAWRLPCSAHPDTPALSALSSILGGGRSARFYEKFHDRLGLVYSIEVHSNQS CCCHHHEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEEEECCCC ETDEGAFTISMDVDRAQRDKVRDLVLQELRNLAEEDFTEDLKRVCKQTRVSRLRRRSSAS CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC GVASEMGADWFGSRNLNLSSEWQEAIERVTTEDLHRVCSTWLSSPNVTEVSLDPPGSNAG CHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC DEERASASAGTALSEHVLGNGMKVVIREDHRLPLAYACMAFKAGCRAENEHDAGVTDLMS CHHHHHHHHCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHH ECLLKGTSTRSAADIARFLEDIGGAINTSTGNNSLSVGCQVLAEDLDAGLELMADVVMNP HHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC SFPEDAFLREKESFVADAEEDMEDPLSVAFRQERKVAYGHVSYGNSPSGTPESLSSLTVQ CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH DIKKQYERIICASNAVICISGDVRKDEVLPLLEKHLGGMRAGTPPALIPTPALRAGREVA HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCEEE VLDKQQAVLVVGVPGVDVASPEMAQALLFQSWCSDMAGPVFTNIREEAGLAYYASSSLFI EECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCEEE GMDAGGICFYLGTSPEQLEEAGRRLEKTLEMIDEQGMTEEELERTRAAALSSRLLAMQSN EECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCC GTLCQMLALDILFGLPLEAFEQQTDAIRNMDLARMNAFIRKVLDPAQPRSWSIVRPPAGE CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: Zn [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA