Click here to switch to the map view.

The map label for this gene is dnaX [H]

Identifier: 187735722

GI number: 187735722

Start: 1475565

End: 1477763

Strand: Reverse

Name: dnaX [H]

Synonym: Amuc_1228

Alternate gene names: 187735722

Gene position: 1477763-1475565 (Counterclockwise)

Preceding gene: 187735725

Following gene: 187735721

Centisome position: 55.47

GC content: 50.48

Gene sequence:

>2199_bases
GTGAGTTACCAGGTCTTTGCCAGAAAATACCGTCCTCTGACATTCGATGACGTCCTTGGACAGGATCATGTTGTCCGGAC
GTTGAAAAACGCCATTGAGCACAACCGTCTCGCCCATGCCTATCTCTTTGTAGGTCCCCGTGGAACGGGAAAGACATCAA
CCGCAAGAATTTTTGCGAAAGCTCTAAACTGCAGCGGTGGGCCCAAAGTGGATTTTGACCCGCATGAAGATATATGTGAA
GAAATTGCAGAAGGGCGGAGCCTGGATGTTCTTGAAATAGACGGAGCATCCAACCGCGGCATTGATCACATCCGGGATCT
CAGGGACAACGTACGGTTCGCTCCGAGCAGAGGAAATTTCCGTATCGTCTATATAGATGAAGTGCACATGCTCACTAAGG
AATCCTTCAACGCCCTGCTCAAAACGCTGGAAGAACCGCCACCTCATGTCAAATTTATTTTCGCAACCACGGAACCCCAT
AAAATACTGCCAACCATTCTATCGCGATGCCAGCGCTTCGACCTGCGCCCCATCCCTTCTGAAATCATTGCAGAACACCT
GCTCCATATCGCTTCTGCAGAGGGAGTAAGTTTGAGCAGGGAAGCAGCCTTTGCTGTCGCCAAAGTGGCGGATGGAGGTA
TGCGGGATGCACAATCCATGCTGGACCAGCTTGTTTCCTTCTGTGGAGATCATATTGAAGAACAGCAGGTACTCCACATT
TTCGGCATTACTTCCCGGGAGACCGTGGCCCATGCTCTGGCGCTTATTTTGAACAAGGAACTTCCCTCTCTCCTGCATCT
TCTGCATGAACAGGCGGAAGCAGGAAGAGACATGAGCCAGTTCCTTTCCGAAATTATCTCCGCCGTGCGTGAAATCCTGG
TCTCTAAAGTAGATCCAGAAGCCAGCTTTGATTCTCTCCCGGAATCCTCCAAGGAGGAACTCGCCGAATTGGTCAAACGC
ACCCATACGGACAAAATCCTGCGTTTGGTGGAAGTTCTGGCGGAAACGGAAGATAAAATGCGCTGGTCCACCAATAAAAG
GCTTCATCTGGAAATGGGCCTGATTAAAGCCGTTCATACTCTGGCTGAGGCCAGCATCAGCGATATTATCATGGCGTTGG
AAGGTGCTCCGCTAGCCACCGCGGCACCGGCCTCTTCTTCAGATCTTGCTTCACAGCAGGAACCAAGTACATTTATTTCC
TCCGCCACGGCACCCACTCCGGCCCCCCGGCAAAACATCCAGTCTCCTGTTGCTGCAACAAACCCAACCCCAGCTACGGA
AGAACATTTGATGGATCCGATTCCAGATTTTTCTTTGTCTTCCCCTGCTTCATCTCCCGCAGTACAGAAAATTCAGAGCA
CTGACGCTCAAGCTTCTCCCCATCCTACGCAGGAAGCCGAACCACAACAGGAAACTCTTACACCCGCTGCCCCCCCCACC
TCTCTTGCCGTTGCAGAGGAAGAATTTCCCTACTCCGCCACTAAATTGCGGACAAAAACCGTACCTGCCTCCGAAGAAAT
CACCCGGCATCCAGACTCCGATGCCTCCGATGTGTCGAAATTTCCTACGGATTCTCCAGAGCCTACTTTTATGGATCCAG
AGGAAAATCTTCCTCTGGAAAGACGAACTAACAGTTTCTTTGACAATCTATTCGATACTCCAAGCACATCATCCCAAACC
CAGGCACCCGTAGAAAAAGAGGAACCGGCAGTTCTGTCCCAACAATCAGGAAGAACAATCACGGAAGAAGACTGGAAAAC
GGTGTTGGAACAAATGTCCGCCAAATTCCCTCTTCAAGCGGACTTTCTAGCCAACAGCGTTTTTTCCGGTTATGATGGTG
TAGCAGTCGCCATTTCTTTTCATCCTTCTGACCGTCAGGGGATGGACAGTCTTGGAACCGGCCCTCTGCGAACAGCTTTG
GAAGCTGCTCTTTCCCAATATATTGGAACCTCTGTTACTATTTCTATCCGTCAGGATTTCTCCATTCCCGAACCCGTGCA
GGAAGAACTGGCTCCTCTGCCTGCACCACCTCCTTCCGCATCCACCATTCCTGCACCTAAACCTCATACCCCGCAGAAAA
AAACCGCAGAGCCTGTCCAGGAAGCTTCCAAAGAGGAAAATGAAGATAACTCTTACTACACGGATCCGCTGATTGATGCT
GCTATGGAGATTTTCCGGGCTCGTATCATTTCCCAATAG

Upstream 100 bases:

>100_bases
CCGTAACGGGAGTGCGCAAGAACCGTTTTATCAACATTTTAAAACAATTACTCTCTATTTTCTTTTCAAACGGGAACTCA
TCTTCTAGTCTTTCTGAACC

Downstream 100 bases:

>100_bases
TCAACTCATCCACCCAGACACAACGACCATGAACATAATGAAAATGATGAAACAGGTCCAGCAAATGCAGGCAGGGCTTG
CGGCCGCTCAAGAAAAACTC

Product: DNA polymerase III, subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 731

Protein sequence:

>732_residues
MSYQVFARKYRPLTFDDVLGQDHVVRTLKNAIEHNRLAHAYLFVGPRGTGKTSTARIFAKALNCSGGPKVDFDPHEDICE
EIAEGRSLDVLEIDGASNRGIDHIRDLRDNVRFAPSRGNFRIVYIDEVHMLTKESFNALLKTLEEPPPHVKFIFATTEPH
KILPTILSRCQRFDLRPIPSEIIAEHLLHIASAEGVSLSREAAFAVAKVADGGMRDAQSMLDQLVSFCGDHIEEQQVLHI
FGITSRETVAHALALILNKELPSLLHLLHEQAEAGRDMSQFLSEIISAVREILVSKVDPEASFDSLPESSKEELAELVKR
THTDKILRLVEVLAETEDKMRWSTNKRLHLEMGLIKAVHTLAEASISDIIMALEGAPLATAAPASSSDLASQQEPSTFIS
SATAPTPAPRQNIQSPVAATNPTPATEEHLMDPIPDFSLSSPASSPAVQKIQSTDAQASPHPTQEAEPQQETLTPAAPPT
SLAVAEEEFPYSATKLRTKTVPASEEITRHPDSDASDVSKFPTDSPEPTFMDPEENLPLERRTNSFFDNLFDTPSTSSQT
QAPVEKEEPAVLSQQSGRTITEEDWKTVLEQMSAKFPLQADFLANSVFSGYDGVAVAISFHPSDRQGMDSLGTGPLRTAL
EAALSQYIGTSVTISIRQDFSIPEPVQEELAPLPAPPPSASTIPAPKPHTPQKKTAEPVQEASKEENEDNSYYTDPLIDA
AMEIFRARIISQ

Sequences:

>Translated_732_residues
MSYQVFARKYRPLTFDDVLGQDHVVRTLKNAIEHNRLAHAYLFVGPRGTGKTSTARIFAKALNCSGGPKVDFDPHEDICE
EIAEGRSLDVLEIDGASNRGIDHIRDLRDNVRFAPSRGNFRIVYIDEVHMLTKESFNALLKTLEEPPPHVKFIFATTEPH
KILPTILSRCQRFDLRPIPSEIIAEHLLHIASAEGVSLSREAAFAVAKVADGGMRDAQSMLDQLVSFCGDHIEEQQVLHI
FGITSRETVAHALALILNKELPSLLHLLHEQAEAGRDMSQFLSEIISAVREILVSKVDPEASFDSLPESSKEELAELVKR
THTDKILRLVEVLAETEDKMRWSTNKRLHLEMGLIKAVHTLAEASISDIIMALEGAPLATAAPASSSDLASQQEPSTFIS
SATAPTPAPRQNIQSPVAATNPTPATEEHLMDPIPDFSLSSPASSPAVQKIQSTDAQASPHPTQEAEPQQETLTPAAPPT
SLAVAEEEFPYSATKLRTKTVPASEEITRHPDSDASDVSKFPTDSPEPTFMDPEENLPLERRTNSFFDNLFDTPSTSSQT
QAPVEKEEPAVLSQQSGRTITEEDWKTVLEQMSAKFPLQADFLANSVFSGYDGVAVAISFHPSDRQGMDSLGTGPLRTAL
EAALSQYIGTSVTISIRQDFSIPEPVQEELAPLPAPPPSASTIPAPKPHTPQKKTAEPVQEASKEENEDNSYYTDPLIDA
AMEIFRARIISQ
>Mature_731_residues
SYQVFARKYRPLTFDDVLGQDHVVRTLKNAIEHNRLAHAYLFVGPRGTGKTSTARIFAKALNCSGGPKVDFDPHEDICEE
IAEGRSLDVLEIDGASNRGIDHIRDLRDNVRFAPSRGNFRIVYIDEVHMLTKESFNALLKTLEEPPPHVKFIFATTEPHK
ILPTILSRCQRFDLRPIPSEIIAEHLLHIASAEGVSLSREAAFAVAKVADGGMRDAQSMLDQLVSFCGDHIEEQQVLHIF
GITSRETVAHALALILNKELPSLLHLLHEQAEAGRDMSQFLSEIISAVREILVSKVDPEASFDSLPESSKEELAELVKRT
HTDKILRLVEVLAETEDKMRWSTNKRLHLEMGLIKAVHTLAEASISDIIMALEGAPLATAAPASSSDLASQQEPSTFISS
ATAPTPAPRQNIQSPVAATNPTPATEEHLMDPIPDFSLSSPASSPAVQKIQSTDAQASPHPTQEAEPQQETLTPAAPPTS
LAVAEEEFPYSATKLRTKTVPASEEITRHPDSDASDVSKFPTDSPEPTFMDPEENLPLERRTNSFFDNLFDTPSTSSQTQ
APVEKEEPAVLSQQSGRTITEEDWKTVLEQMSAKFPLQADFLANSVFSGYDGVAVAISFHPSDRQGMDSLGTGPLRTALE
AALSQYIGTSVTISIRQDFSIPEPVQEELAPLPAPPPSASTIPAPKPHTPQKKTAEPVQEASKEENEDNSYYTDPLIDAA
MEIFRARIISQ

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=298, Percent_Identity=28.8590604026846, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI4506491, Length=296, Percent_Identity=28.3783783783784, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI31881687, Length=296, Percent_Identity=28.3783783783784, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI194306571, Length=295, Percent_Identity=29.1525423728814, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI194306567, Length=295, Percent_Identity=29.1525423728814, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI194306569, Length=214, Percent_Identity=27.5700934579439, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI31563534, Length=271, Percent_Identity=23.9852398523985, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786676, Length=358, Percent_Identity=38.5474860335196, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI1787119, Length=235, Percent_Identity=25.9574468085106, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71986063, Length=298, Percent_Identity=26.8456375838926, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17554730, Length=270, Percent_Identity=27.7777777777778, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17541988, Length=226, Percent_Identity=26.1061946902655, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324039, Length=221, Percent_Identity=31.6742081447964, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322528, Length=261, Percent_Identity=25.6704980842912, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324478, Length=229, Percent_Identity=26.6375545851528, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19921076, Length=257, Percent_Identity=28.4046692607004, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI18859927, Length=296, Percent_Identity=25, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17647857, Length=229, Percent_Identity=25.764192139738, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 80231; Mature: 80100

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQVFARKYRPLTFDDVLGQDHVVRTLKNAIEHNRLAHAYLFVGPRGTGKTSTARIFAK
CCCHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHH
ALNCSGGPKVDFDPHEDICEEIAEGRSLDVLEIDGASNRGIDHIRDLRDNVRFAPSRGNF
HHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCEECCCCCCE
RIVYIDEVHMLTKESFNALLKTLEEPPPHVKFIFATTEPHKILPTILSRCQRFDLRPIPS
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCH
EIIAEHLLHIASAEGVSLSREAAFAVAKVADGGMRDAQSMLDQLVSFCGDHIEEQQVLHI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEHE
FGITSRETVAHALALILNKELPSLLHLLHEQAEAGRDMSQFLSEIISAVREILVSKVDPE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
ASFDSLPESSKEELAELVKRTHTDKILRLVEVLAETEDKMRWSTNKRLHLEMGLIKAVHT
CCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
LAEASISDIIMALEGAPLATAAPASSSDLASQQEPSTFISSATAPTPAPRQNIQSPVAAT
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHCCCCCCCCCHHHHCCCCCCC
NPTPATEEHLMDPIPDFSLSSPASSPAVQKIQSTDAQASPHPTQEAEPQQETLTPAAPPT
CCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCC
SLAVAEEEFPYSATKLRTKTVPASEEITRHPDSDASDVSKFPTDSPEPTFMDPEENLPLE
CEEECHHCCCCCHHHHEECCCCCHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHH
RRTNSFFDNLFDTPSTSSQTQAPVEKEEPAVLSQQSGRTITEEDWKTVLEQMSAKFPLQA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCHH
DFLANSVFSGYDGVAVAISFHPSDRQGMDSLGTGPLRTALEAALSQYIGTSVTISIRQDF
HHHHHHHHCCCCCEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCC
SIPEPVQEELAPLPAPPPSASTIPAPKPHTPQKKTAEPVQEASKEENEDNSYYTDPLIDA
CCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCHHHHH
AMEIFRARIISQ
HHHHHHHHHCCC
>Mature Secondary Structure 
SYQVFARKYRPLTFDDVLGQDHVVRTLKNAIEHNRLAHAYLFVGPRGTGKTSTARIFAK
CCHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHH
ALNCSGGPKVDFDPHEDICEEIAEGRSLDVLEIDGASNRGIDHIRDLRDNVRFAPSRGNF
HHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCEECCCCCCE
RIVYIDEVHMLTKESFNALLKTLEEPPPHVKFIFATTEPHKILPTILSRCQRFDLRPIPS
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCH
EIIAEHLLHIASAEGVSLSREAAFAVAKVADGGMRDAQSMLDQLVSFCGDHIEEQQVLHI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEHE
FGITSRETVAHALALILNKELPSLLHLLHEQAEAGRDMSQFLSEIISAVREILVSKVDPE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
ASFDSLPESSKEELAELVKRTHTDKILRLVEVLAETEDKMRWSTNKRLHLEMGLIKAVHT
CCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
LAEASISDIIMALEGAPLATAAPASSSDLASQQEPSTFISSATAPTPAPRQNIQSPVAAT
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHCCCCCCCCCHHHHCCCCCCC
NPTPATEEHLMDPIPDFSLSSPASSPAVQKIQSTDAQASPHPTQEAEPQQETLTPAAPPT
CCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCC
SLAVAEEEFPYSATKLRTKTVPASEEITRHPDSDASDVSKFPTDSPEPTFMDPEENLPLE
CEEECHHCCCCCHHHHEECCCCCHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHH
RRTNSFFDNLFDTPSTSSQTQAPVEKEEPAVLSQQSGRTITEEDWKTVLEQMSAKFPLQA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCHH
DFLANSVFSGYDGVAVAISFHPSDRQGMDSLGTGPLRTALEAALSQYIGTSVTISIRQDF
HHHHHHHHCCCCCEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCC
SIPEPVQEELAPLPAPPPSASTIPAPKPHTPQKKTAEPVQEASKEENEDNSYYTDPLIDA
CCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCHHHHH
AMEIFRARIISQ
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]