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The map label for this gene is dapL [H]

Identifier: 187735679

GI number: 187735679

Start: 1420055

End: 1421650

Strand: Direct

Name: dapL [H]

Synonym: Amuc_1185

Alternate gene names: 187735679

Gene position: 1420055-1421650 (Clockwise)

Preceding gene: 187735676

Following gene: 187735680

Centisome position: 53.3

GC content: 55.76

Gene sequence:

>1596_bases
ATGTCCCTAGAAGTTCCGGTTTCAAAAGCAGGACTGACGCAGAACGGGGACGAAGCTTGCCGGCTTCTTCAGGGCCATGA
TGCCCCGCAGAATGAAGAGGTTCCCTTGCTGGGCATCCGCCTGCCCGTTCTTAGGAATTTTGCCGGGAAGAAGCTCAGGA
GAATCTGGCAGGACAGGATGTCGGCGAGGTGCGTGGACCCTCAAAAGGGCAGGAGCAGCCGCTTTTACACGGCGGAAACT
GCGGCAGGGGGGGAAGCTGCGCCGTTTCGTGACGCAGGGAAGGACGGCATGCCGGAACGGGGCCTTGATTCCGTCCCGTT
CCGGGTATGGAATGAGGCGCTTACTATTAAAACCATGCCTAACATTAACGATAACTTCCTCAAGTTGCAGGCGGGATATT
TGTTCCCGGAAATAGGGCGCCGCGTGAATGCGTTTGCCGAATCCCATCCGGAGGCGGCCAAAAGGCTGATTCGCTGCGGC
ATCGGCGATGTGACGGAGCCGCTTCCCATGGCGGCTATTGAAGCCATGCACCGGGCCGTGGATGATTTGTCCACTCATGA
ACGTTTTCACGGCTATGGGCCGGAGCAGGGGTATTTCTGGCTGAGGGAGGCAATTGCCAAAAAAGCCTATCAGGCCCACG
GCGTGCATGTGGAAGTGGATGAGATTTACGTGTCTGACGGAGCCAAATGCGACACGGGAAACATTCTGGATATTTTCGGG
CCCGGCAACAGAATCGCCGTGCCGGATCCGGTTTATCCCGTGTATGTGGATACCAATGTCATGGCCGGGAATACCGGGAG
TTCCAGCCCGGATGGTTCTTATGAAGGGCTGGTGTATCTGCCGTGCACTCCGGAAAATAATTTTGTGCCGCAATTGCCTG
ATGAGCATGTGGATTTGATTTACCTGTGCTTCCCGAACAATCCTACCGGGGCCGTAGCTTCCCGGAATGAACTGCTGAAA
TGGGTGGAATACGCCCGGGCGAACCGTGCCATTATCCTTTATGATTCCGCTTATGAGGCTTTCATACAGGATTCTTCCAT
TCCCAGATCCATTTTTGAAATTCCCGGCGCGCGGGATTGCGCCATTGAGTTCCGTTCCTTCTCCAAGCAAGGAGGCTTTA
CAGGGGTGCGCTGCGGTTATGTGGTGATTCCCAAGGAATTGCACGGATATGATTCCGAAGGGAACAAGGTTTCTATCAGC
CGACTCTGGAGCCGCCGCACCAGCACGAAATTCAACGGCGCTTCCTATATTGTCCAGCGGGGTGCCGCGGCTTTGTTCAC
CATGGAGGGCATGGCCCAGACTGCCGCGCTCATCAGCCATTACCTGGGGAATGCTTCGCTTCTGCTGAATGCCTGCCGTC
AGGCGGGCATGCGCGTGTGGGGCGGGGAAAACGCCCCTTATGTATGGGTACAGTGTCCGGACGGTCTGGACAGCTGGCAA
ATGTTTGACAAGATGCTGCATGAGGCGAATGTGGTTATTACGCCTGGTTCCGGTTTTGGTTCCAGGGGGGAAGGGTTCTT
CCGCATTTCCGCGTTTAATTCACGGGAAAACGTGGATGAAGTCTGCCGCCGCATCCACAGCCTGTTTGCCAGATAG

Upstream 100 bases:

>100_bases
CCGCGGACGTCAATGATTTCCATTTCATTCATGATCATAAGATTTCTTTTTGTCCTTTTTAGACAGGGAAACAGGCTTTC
CCGTTCCGGAGAAGCATGTC

Downstream 100 bases:

>100_bases
AAGGGCGTTTTCAGACAGATGTCCAGGCCGCGGTGCAAAACACCGCGGCCTGTGTATTTCTTTCCGGGTGGGTTGATGAC
CGTGGCATTGTATTTCCTGC

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MSLEVPVSKAGLTQNGDEACRLLQGHDAPQNEEVPLLGIRLPVLRNFAGKKLRRIWQDRMSARCVDPQKGRSSRFYTAET
AAGGEAAPFRDAGKDGMPERGLDSVPFRVWNEALTIKTMPNINDNFLKLQAGYLFPEIGRRVNAFAESHPEAAKRLIRCG
IGDVTEPLPMAAIEAMHRAVDDLSTHERFHGYGPEQGYFWLREAIAKKAYQAHGVHVEVDEIYVSDGAKCDTGNILDIFG
PGNRIAVPDPVYPVYVDTNVMAGNTGSSSPDGSYEGLVYLPCTPENNFVPQLPDEHVDLIYLCFPNNPTGAVASRNELLK
WVEYARANRAIILYDSAYEAFIQDSSIPRSIFEIPGARDCAIEFRSFSKQGGFTGVRCGYVVIPKELHGYDSEGNKVSIS
RLWSRRTSTKFNGASYIVQRGAAALFTMEGMAQTAALISHYLGNASLLLNACRQAGMRVWGGENAPYVWVQCPDGLDSWQ
MFDKMLHEANVVITPGSGFGSRGEGFFRISAFNSRENVDEVCRRIHSLFAR

Sequences:

>Translated_531_residues
MSLEVPVSKAGLTQNGDEACRLLQGHDAPQNEEVPLLGIRLPVLRNFAGKKLRRIWQDRMSARCVDPQKGRSSRFYTAET
AAGGEAAPFRDAGKDGMPERGLDSVPFRVWNEALTIKTMPNINDNFLKLQAGYLFPEIGRRVNAFAESHPEAAKRLIRCG
IGDVTEPLPMAAIEAMHRAVDDLSTHERFHGYGPEQGYFWLREAIAKKAYQAHGVHVEVDEIYVSDGAKCDTGNILDIFG
PGNRIAVPDPVYPVYVDTNVMAGNTGSSSPDGSYEGLVYLPCTPENNFVPQLPDEHVDLIYLCFPNNPTGAVASRNELLK
WVEYARANRAIILYDSAYEAFIQDSSIPRSIFEIPGARDCAIEFRSFSKQGGFTGVRCGYVVIPKELHGYDSEGNKVSIS
RLWSRRTSTKFNGASYIVQRGAAALFTMEGMAQTAALISHYLGNASLLLNACRQAGMRVWGGENAPYVWVQCPDGLDSWQ
MFDKMLHEANVVITPGSGFGSRGEGFFRISAFNSRENVDEVCRRIHSLFAR
>Mature_530_residues
SLEVPVSKAGLTQNGDEACRLLQGHDAPQNEEVPLLGIRLPVLRNFAGKKLRRIWQDRMSARCVDPQKGRSSRFYTAETA
AGGEAAPFRDAGKDGMPERGLDSVPFRVWNEALTIKTMPNINDNFLKLQAGYLFPEIGRRVNAFAESHPEAAKRLIRCGI
GDVTEPLPMAAIEAMHRAVDDLSTHERFHGYGPEQGYFWLREAIAKKAYQAHGVHVEVDEIYVSDGAKCDTGNILDIFGP
GNRIAVPDPVYPVYVDTNVMAGNTGSSSPDGSYEGLVYLPCTPENNFVPQLPDEHVDLIYLCFPNNPTGAVASRNELLKW
VEYARANRAIILYDSAYEAFIQDSSIPRSIFEIPGARDCAIEFRSFSKQGGFTGVRCGYVVIPKELHGYDSEGNKVSISR
LWSRRTSTKFNGASYIVQRGAAALFTMEGMAQTAALISHYLGNASLLLNACRQAGMRVWGGENAPYVWVQCPDGLDSWQM
FDKMLHEANVVITPGSGFGSRGEGFFRISAFNSRENVDEVCRRIHSLFAR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=346, Percent_Identity=28.6127167630058, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788627, Length=247, Percent_Identity=27.9352226720648, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 58734; Mature: 58603

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEVPVSKAGLTQNGDEACRLLQGHDAPQNEEVPLLGIRLPVLRNFAGKKLRRIWQDRM
CCCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
SARCVDPQKGRSSRFYTAETAAGGEAAPFRDAGKDGMPERGLDSVPFRVWNEALTIKTMP
HCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEEECC
NINDNFLKLQAGYLFPEIGRRVNAFAESHPEAAKRLIRCGIGDVTEPLPMAAIEAMHRAV
CCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
DDLSTHERFHGYGPEQGYFWLREAIAKKAYQAHGVHVEVDEIYVSDGAKCDTGNILDIFG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCEEEEEC
PGNRIAVPDPVYPVYVDTNVMAGNTGSSSPDGSYEGLVYLPCTPENNFVPQLPDEHVDLI
CCCEECCCCCCEEEEEECEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEE
YLCFPNNPTGAVASRNELLKWVEYARANRAIILYDSAYEAFIQDSSIPRSIFEIPGARDC
EEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCHHHHHCCCCCHH
AIEFRSFSKQGGFTGVRCGYVVIPKELHGYDSEGNKVSISRLWSRRTSTKFNGASYIVQR
HHHHHHHHCCCCCCEEEEEEEEECHHHCCCCCCCCEEEHHHHHHHHCCCCCCCHHHHHHC
GAAALFTMEGMAQTAALISHYLGNASLLLNACRQAGMRVWGGENAPYVWVQCPDGLDSWQ
CCHHEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCHHH
MFDKMLHEANVVITPGSGFGSRGEGFFRISAFNSRENVDEVCRRIHSLFAR
HHHHHHHHCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLEVPVSKAGLTQNGDEACRLLQGHDAPQNEEVPLLGIRLPVLRNFAGKKLRRIWQDRM
CCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
SARCVDPQKGRSSRFYTAETAAGGEAAPFRDAGKDGMPERGLDSVPFRVWNEALTIKTMP
HCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEEECC
NINDNFLKLQAGYLFPEIGRRVNAFAESHPEAAKRLIRCGIGDVTEPLPMAAIEAMHRAV
CCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
DDLSTHERFHGYGPEQGYFWLREAIAKKAYQAHGVHVEVDEIYVSDGAKCDTGNILDIFG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCEEEEEC
PGNRIAVPDPVYPVYVDTNVMAGNTGSSSPDGSYEGLVYLPCTPENNFVPQLPDEHVDLI
CCCEECCCCCCEEEEEECEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEE
YLCFPNNPTGAVASRNELLKWVEYARANRAIILYDSAYEAFIQDSSIPRSIFEIPGARDC
EEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCCCCCHHHHHCCCCCHH
AIEFRSFSKQGGFTGVRCGYVVIPKELHGYDSEGNKVSISRLWSRRTSTKFNGASYIVQR
HHHHHHHHCCCCCCEEEEEEEEECHHHCCCCCCCCEEEHHHHHHHHCCCCCCCHHHHHHC
GAAALFTMEGMAQTAALISHYLGNASLLLNACRQAGMRVWGGENAPYVWVQCPDGLDSWQ
CCHHEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCHHH
MFDKMLHEANVVITPGSGFGSRGEGFFRISAFNSRENVDEVCRRIHSLFAR
HHHHHHHHCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA