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The map label for this gene is ydeN [H]

Identifier: 187735676

GI number: 187735676

Start: 1416784

End: 1418181

Strand: Direct

Name: ydeN [H]

Synonym: Amuc_1182

Alternate gene names: 187735676

Gene position: 1416784-1418181 (Clockwise)

Preceding gene: 187735675

Following gene: 187735679

Centisome position: 53.18

GC content: 54.79

Gene sequence:

>1398_bases
ATGATGAAGGAAGTGCGCCTTTTGTTAATTCTGTGCGGTTTGTTTTGCGGAACGGCAGTTGCGCAGCCCCGCCTTTCCTC
ACCGCCGAACATGATTGTCATTCTGGCGGATGACCTGGGTTATGGGGATTTGGGCTGTACAGGTTCCAAGCAGATAAAAA
CGCCTTCCCTTGACCGGCTGGCAAGGGAGGGGGTGTTCTGCTCCCGGGCGTATGTGACGGCGCCGATGTGTTCTCCCTCC
CGCATGGGACTGCTGACGGGGCGTTTCCCCAAGCGTTACGGCATCACGACGAATCCCAATATCCAGATGGATTATCTTCC
GGAGTCCCACTACGGGCTGCCGCAGACGGAGAAATTGATTCCGGAGTATTTGGCTCCCTGTGGGTACCGGAGCGCGGTAT
TCGGCAAGTGGCATCTTGGCCACACGAAGGGATATACGCCGCCGGAGCGCGGTTTTACGCATTGGTGGGGGTTCCTGGGC
GGTTCCCGGCATTATTTTCCCGTGAAGAAAGAGGCTGAAGGCCTGAATCCCTCCATGATTGTATCCAATTTTACGGATAA
GACGGACATCACCTATTTGACGGACGATATTACAGACCGGGCGGTTGAATTTCTGCAGGAAGCCGGAAAGGATAAGAAAC
CGTTTTTCATGTTCGTTTCCTACAACGCCCCCCATTGGCCCAATGAAGCCAAACCGGAGGATATCGCCAAATTCAGGAAC
GTGCAGAACGGGGAACGACGGGTTTATTGCGCCATGGTATATGCGATGGACAGGGGAATAGGCCGCATTCTGGATGCCTT
GAAAGCAGACGGTTTGGAAAAGGATACCATCGTCGTCTTCCTGTCGGACAATGGAGGCGCTCCGGAAGCTTCTTCCTGCA
ACGCCCCTTTCCGGGGTGCCAAGAGGCAGCATTTTGAAGGAGGTGTTCGCGTACCTTTTATTATCAGATATCCGGCGGAC
AAGCGTTTGGTTCCCGGAAGCGTTTGCAGACAGCCCGTTTCCTCCGTGGATTTGCTTCCCGCTTTGCTGAAGGCGAATGG
CCGTCACATTCCCAGGAAGCTGGACGGCATGGATATTCTGGAGCTGGTGGGGAACAAGGGAGCTCCCGTTCCGCGCACCT
TTTTCTGGTGCACGGATTACACGTCCGCTGTGCTGACCGGTGATATGAAGTACCTGCTGGTCCCGGATCGCGCTCCGCAG
TTTTATAATGTGGCGGACGATCCCCAGGAACAGAGGGATTTGTATTTTTCCAGGCACCAGGATGCGGATCTCCTCGCTAA
AAAGCTGGGAACATACCTGACTACGACGCCTGCATGCCGTTTTCCCGACAGTATCAGCTGGTCCGCCAAATTGATGAGGG
AGTATGACAAGACTGCGCCGGACAGGCAGCCTGAGTAA

Upstream 100 bases:

>100_bases
CATGGACAGCGGGCAGGGTTTCCATTTGAGGCATGATAGCGGGAATTCCGGGAATGAGGTTTTTTGATTGATATGGAGAA
TAAGGTACGTAGATTAACGT

Downstream 100 bases:

>100_bases
GGCTGCGTTGGCTTTGTTCCGTATTCCGTCCTGCATGCCAGCGTTTGGGAACCTATTACTACGGCGGGAGAGGGGGAGAA
ACCGCGTGCATGGTTTTCTT

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MMKEVRLLLILCGLFCGTAVAQPRLSSPPNMIVILADDLGYGDLGCTGSKQIKTPSLDRLAREGVFCSRAYVTAPMCSPS
RMGLLTGRFPKRYGITTNPNIQMDYLPESHYGLPQTEKLIPEYLAPCGYRSAVFGKWHLGHTKGYTPPERGFTHWWGFLG
GSRHYFPVKKEAEGLNPSMIVSNFTDKTDITYLTDDITDRAVEFLQEAGKDKKPFFMFVSYNAPHWPNEAKPEDIAKFRN
VQNGERRVYCAMVYAMDRGIGRILDALKADGLEKDTIVVFLSDNGGAPEASSCNAPFRGAKRQHFEGGVRVPFIIRYPAD
KRLVPGSVCRQPVSSVDLLPALLKANGRHIPRKLDGMDILELVGNKGAPVPRTFFWCTDYTSAVLTGDMKYLLVPDRAPQ
FYNVADDPQEQRDLYFSRHQDADLLAKKLGTYLTTTPACRFPDSISWSAKLMREYDKTAPDRQPE

Sequences:

>Translated_465_residues
MMKEVRLLLILCGLFCGTAVAQPRLSSPPNMIVILADDLGYGDLGCTGSKQIKTPSLDRLAREGVFCSRAYVTAPMCSPS
RMGLLTGRFPKRYGITTNPNIQMDYLPESHYGLPQTEKLIPEYLAPCGYRSAVFGKWHLGHTKGYTPPERGFTHWWGFLG
GSRHYFPVKKEAEGLNPSMIVSNFTDKTDITYLTDDITDRAVEFLQEAGKDKKPFFMFVSYNAPHWPNEAKPEDIAKFRN
VQNGERRVYCAMVYAMDRGIGRILDALKADGLEKDTIVVFLSDNGGAPEASSCNAPFRGAKRQHFEGGVRVPFIIRYPAD
KRLVPGSVCRQPVSSVDLLPALLKANGRHIPRKLDGMDILELVGNKGAPVPRTFFWCTDYTSAVLTGDMKYLLVPDRAPQ
FYNVADDPQEQRDLYFSRHQDADLLAKKLGTYLTTTPACRFPDSISWSAKLMREYDKTAPDRQPE
>Mature_465_residues
MMKEVRLLLILCGLFCGTAVAQPRLSSPPNMIVILADDLGYGDLGCTGSKQIKTPSLDRLAREGVFCSRAYVTAPMCSPS
RMGLLTGRFPKRYGITTNPNIQMDYLPESHYGLPQTEKLIPEYLAPCGYRSAVFGKWHLGHTKGYTPPERGFTHWWGFLG
GSRHYFPVKKEAEGLNPSMIVSNFTDKTDITYLTDDITDRAVEFLQEAGKDKKPFFMFVSYNAPHWPNEAKPEDIAKFRN
VQNGERRVYCAMVYAMDRGIGRILDALKADGLEKDTIVVFLSDNGGAPEASSCNAPFRGAKRQHFEGGVRVPFIIRYPAD
KRLVPGSVCRQPVSSVDLLPALLKANGRHIPRKLDGMDILELVGNKGAPVPRTFFWCTDYTSAVLTGDMKYLLVPDRAPQ
FYNVADDPQEQRDLYFSRHQDADLLAKKLGTYLTTTPACRFPDSISWSAKLMREYDKTAPDRQPE

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=371, Percent_Identity=34.5013477088949, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI38569407, Length=358, Percent_Identity=34.6368715083799, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI38569405, Length=358, Percent_Identity=34.6368715083799, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI109389362, Length=361, Percent_Identity=34.6260387811634, Blast_Score=182, Evalue=8e-46,
Organism=Homo sapiens, GI146229331, Length=381, Percent_Identity=31.758530183727, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI146229329, Length=381, Percent_Identity=31.758530183727, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI6005990, Length=381, Percent_Identity=31.758530183727, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI146229324, Length=381, Percent_Identity=31.758530183727, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI59797060, Length=473, Percent_Identity=29.1754756871036, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI45430057, Length=390, Percent_Identity=30, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI157266309, Length=415, Percent_Identity=29.1566265060241, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI58743319, Length=437, Percent_Identity=28.1464530892449, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI189571643, Length=406, Percent_Identity=24.384236453202, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI189571641, Length=406, Percent_Identity=24.384236453202, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI189571638, Length=406, Percent_Identity=24.384236453202, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI189571636, Length=406, Percent_Identity=24.384236453202, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI53831991, Length=143, Percent_Identity=39.8601398601399, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI240255478, Length=383, Percent_Identity=26.1096605744125, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI240255483, Length=383, Percent_Identity=26.1096605744125, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI29789100, Length=383, Percent_Identity=26.1096605744125, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI31742482, Length=158, Percent_Identity=37.9746835443038, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI71852586, Length=135, Percent_Identity=37.7777777777778, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI71852584, Length=136, Percent_Identity=37.5, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI146229327, Length=303, Percent_Identity=27.3927392739274, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI4504061, Length=378, Percent_Identity=22.7513227513227, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4557659, Length=392, Percent_Identity=24.4897959183673, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI5360208, Length=311, Percent_Identity=24.7588424437299, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI87081924, Length=407, Percent_Identity=29.7297297297297, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1790112, Length=476, Percent_Identity=26.890756302521, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1790233, Length=369, Percent_Identity=27.9132791327913, Blast_Score=116, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI115533416, Length=432, Percent_Identity=29.3981481481481, Blast_Score=161, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI115533418, Length=415, Percent_Identity=29.3975903614458, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17568795, Length=382, Percent_Identity=25.6544502617801, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17559078, Length=232, Percent_Identity=29.7413793103448, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281363223, Length=411, Percent_Identity=34.7931873479319, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI281366397, Length=357, Percent_Identity=35.2941176470588, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI281366395, Length=357, Percent_Identity=35.2941176470588, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24666163, Length=357, Percent_Identity=35.2941176470588, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24666175, Length=387, Percent_Identity=33.0749354005168, Blast_Score=204, Evalue=9e-53,
Organism=Drosophila melanogaster, GI24666109, Length=397, Percent_Identity=34.0050377833753, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24653364, Length=395, Percent_Identity=27.0886075949367, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24647401, Length=378, Percent_Identity=27.5132275132275, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19922168, Length=395, Percent_Identity=26.5822784810127, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21356831, Length=389, Percent_Identity=25.9640102827763, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.12

Molecular weight: Translated: 52131; Mature: 52131

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKEVRLLLILCGLFCGTAVAQPRLSSPPNMIVILADDLGYGDLGCTGSKQIKTPSLDRL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHH
AREGVFCSRAYVTAPMCSPSRMGLLTGRFPKRYGITTNPNIQMDYLPESHYGLPQTEKLI
HHCCCEEEHHEEECCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHH
PEYLAPCGYRSAVFGKWHLGHTKGYTPPERGFTHWWGFLGGSRHYFPVKKEAEGLNPSMI
HHHHCCCCCCHHEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHCCCCCHHEE
VSNFTDKTDITYLTDDITDRAVEFLQEAGKDKKPFFMFVSYNAPHWPNEAKPEDIAKFRN
EECCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHC
VQNGERRVYCAMVYAMDRGIGRILDALKADGLEKDTIVVFLSDNGGAPEASSCNAPFRGA
CCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
KRQHFEGGVRVPFIIRYPADKRLVPGSVCRQPVSSVDLLPALLKANGRHIPRKLDGMDIL
CHHHCCCCCCCCEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHH
ELVGNKGAPVPRTFFWCTDYTSAVLTGDMKYLLVPDRAPQFYNVADDPQEQRDLYFSRHQ
HHHCCCCCCCCCEEEEECCCCCEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCC
DADLLAKKLGTYLTTTPACRFPDSISWSAKLMREYDKTAPDRQPE
CHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMKEVRLLLILCGLFCGTAVAQPRLSSPPNMIVILADDLGYGDLGCTGSKQIKTPSLDRL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHH
AREGVFCSRAYVTAPMCSPSRMGLLTGRFPKRYGITTNPNIQMDYLPESHYGLPQTEKLI
HHCCCEEEHHEEECCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHH
PEYLAPCGYRSAVFGKWHLGHTKGYTPPERGFTHWWGFLGGSRHYFPVKKEAEGLNPSMI
HHHHCCCCCCHHEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHCCCCCHHEE
VSNFTDKTDITYLTDDITDRAVEFLQEAGKDKKPFFMFVSYNAPHWPNEAKPEDIAKFRN
EECCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHC
VQNGERRVYCAMVYAMDRGIGRILDALKADGLEKDTIVVFLSDNGGAPEASSCNAPFRGA
CCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
KRQHFEGGVRVPFIIRYPADKRLVPGSVCRQPVSSVDLLPALLKANGRHIPRKLDGMDIL
CHHHCCCCCCCCEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHH
ELVGNKGAPVPRTFFWCTDYTSAVLTGDMKYLLVPDRAPQFYNVADDPQEQRDLYFSRHQ
HHHCCCCCCCCCEEEEECCCCCEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCC
DADLLAKKLGTYLTTTPACRFPDSISWSAKLMREYDKTAPDRQPE
CHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]