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The map label for this gene is apbE [H]

Identifier: 187735680

GI number: 187735680

Start: 1422095

End: 1423039

Strand: Direct

Name: apbE [H]

Synonym: Amuc_1186

Alternate gene names: 187735680

Gene position: 1422095-1423039 (Clockwise)

Preceding gene: 187735679

Following gene: 187735681

Centisome position: 53.38

GC content: 59.47

Gene sequence:

>945_bases
ATGGGTACGGTGTTCACGGTGCGCGCTTATCCCGGGAGTGGCATGGACGCGAAAGATGCGGAGAGGATTTGCGGGGAGGC
TCTGGCCTGTGCCGTCCACTGGGAAAAAGTGATGTCCGCCATGGATGCGGAAAGCGGTCTGACCCGGCTTAATGCTGCGG
AATACGGCATTTCCGTGCCTGTTTCTCCGGAATTGGAAAGGGTGCTTCTTCTGTCCCTGAATTATGCCCGGCTGACAAAC
GGTGCTTTTGATCCCACACTGGGACCCTGCATTCGCCTGTGGAAAAAGAGCCGCCGCCTTGGCGTCCTCCCGTCCGATGA
GGAGCGGGAATGCGCGCTCCGGGCATGCGGATGGGAAAAGTTGTCCGTCCGTAAGGGAATGGCGGTCAAGGCGGTTTCTG
GAATGAGGCTGGATTTGGGAGGCATGGGCAAGGGCTTTGCCGTGGACCGAATGGCGGAGATGTTGAAAACAAGGGGTATA
TGTTCCTTCTTCATAGACAGTACCAGCGATGTTCTGGCCGGCGCTCCTCCTCCCGGGGAACCGGGATGGCGGCTGCGGGT
GGATACAGGAAGAGGGCAGGGGGAAGTGTTGCTGTTGAGCCATGCGGCCGTTTCCACTTCCGGGAGTGCCCGTCAGATGG
TGAAAATTGGCGGGAAAGCGTATTCCCACGTGCTTGATCCCCGGTCGGGGCTGGGCGTTACGGAAGGGAGGCAGGTGAGC
GTCCGGGCGTCTTCCGCTGCGCTGGCGGATGCCCTGGCGACGGCAGGGTGTGTGATGCGTGAGGAGGAGTTCCGTTCCCT
GGCGGCCGGATTGCCGGGAGTGTCCGTTCCGGCCTTTTTTCAAAGTCCGCCATGTTCTGCGGGGGAAACGCAGAAACAGG
ATGGACTGCGGAAGGAGGGAGGAATGGGGTCAATGAAAGGAATGACAAAGCAACTACGTTTTTAA

Upstream 100 bases:

>100_bases
CACCATCCGGGGGCAGGAAGGGGAAGCGGAGCTTCCTTCTGTGGAGCCGCTTTCCTGTGCGCATGCCCCAGATGGGAGGG
TAACAGTTCGGGGGTCGGTT

Downstream 100 bases:

>100_bases
GGTACACCTTTATAACCCTGTTTATGAGATTGTACCATTTTTTACTCCCTGCCGTTGTCAGCGCTGCCGTATCTGCGTCA
TTTGGGGCAGAGTTCCCTAA

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MGTVFTVRAYPGSGMDAKDAERICGEALACAVHWEKVMSAMDAESGLTRLNAAEYGISVPVSPELERVLLLSLNYARLTN
GAFDPTLGPCIRLWKKSRRLGVLPSDEERECALRACGWEKLSVRKGMAVKAVSGMRLDLGGMGKGFAVDRMAEMLKTRGI
CSFFIDSTSDVLAGAPPPGEPGWRLRVDTGRGQGEVLLLSHAAVSTSGSARQMVKIGGKAYSHVLDPRSGLGVTEGRQVS
VRASSAALADALATAGCVMREEEFRSLAAGLPGVSVPAFFQSPPCSAGETQKQDGLRKEGGMGSMKGMTKQLRF

Sequences:

>Translated_314_residues
MGTVFTVRAYPGSGMDAKDAERICGEALACAVHWEKVMSAMDAESGLTRLNAAEYGISVPVSPELERVLLLSLNYARLTN
GAFDPTLGPCIRLWKKSRRLGVLPSDEERECALRACGWEKLSVRKGMAVKAVSGMRLDLGGMGKGFAVDRMAEMLKTRGI
CSFFIDSTSDVLAGAPPPGEPGWRLRVDTGRGQGEVLLLSHAAVSTSGSARQMVKIGGKAYSHVLDPRSGLGVTEGRQVS
VRASSAALADALATAGCVMREEEFRSLAAGLPGVSVPAFFQSPPCSAGETQKQDGLRKEGGMGSMKGMTKQLRF
>Mature_313_residues
GTVFTVRAYPGSGMDAKDAERICGEALACAVHWEKVMSAMDAESGLTRLNAAEYGISVPVSPELERVLLLSLNYARLTNG
AFDPTLGPCIRLWKKSRRLGVLPSDEERECALRACGWEKLSVRKGMAVKAVSGMRLDLGGMGKGFAVDRMAEMLKTRGIC
SFFIDSTSDVLAGAPPPGEPGWRLRVDTGRGQGEVLLLSHAAVSTSGSARQMVKIGGKAYSHVLDPRSGLGVTEGRQVSV
RASSAALADALATAGCVMREEEFRSLAAGLPGVSVPAFFQSPPCSAGETQKQDGLRKEGGMGSMKGMTKQLRF

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=267, Percent_Identity=26.9662921348315, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 33303; Mature: 33172

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTVFTVRAYPGSGMDAKDAERICGEALACAVHWEKVMSAMDAESGLTRLNAAEYGISVP
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCC
VSPELERVLLLSLNYARLTNGAFDPTLGPCIRLWKKSRRLGVLPSDEERECALRACGWEK
CCCCHHHEEHEECCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHH
LSVRKGMAVKAVSGMRLDLGGMGKGFAVDRMAEMLKTRGICSFFIDSTSDVLAGAPPPGE
HHHHCCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCCC
PGWRLRVDTGRGQGEVLLLSHAAVSTSGSARQMVKIGGKAYSHVLDPRSGLGVTEGRQVS
CCCEEEEECCCCCCCEEEEEECEECCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCEEE
VRASSAALADALATAGCVMREEEFRSLAAGLPGVSVPAFFQSPPCSAGETQKQDGLRKEG
EECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHCCCHHCC
GMGSMKGMTKQLRF
CCCHHHHHHHHHCC
>Mature Secondary Structure 
GTVFTVRAYPGSGMDAKDAERICGEALACAVHWEKVMSAMDAESGLTRLNAAEYGISVP
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCC
VSPELERVLLLSLNYARLTNGAFDPTLGPCIRLWKKSRRLGVLPSDEERECALRACGWEK
CCCCHHHEEHEECCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHH
LSVRKGMAVKAVSGMRLDLGGMGKGFAVDRMAEMLKTRGICSFFIDSTSDVLAGAPPPGE
HHHHCCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCCC
PGWRLRVDTGRGQGEVLLLSHAAVSTSGSARQMVKIGGKAYSHVLDPRSGLGVTEGRQVS
CCCEEEEECCCCCCCEEEEEECEECCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCEEE
VRASSAALADALATAGCVMREEEFRSLAAGLPGVSVPAFFQSPPCSAGETQKQDGLRKEG
EECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHCCCHHCC
GMGSMKGMTKQLRF
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]