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The map label for this gene is obg [H]

Identifier: 187735234

GI number: 187735234

Start: 858403

End: 859473

Strand: Direct

Name: obg [H]

Synonym: Amuc_0728

Alternate gene names: 187735234

Gene position: 858403-859473 (Clockwise)

Preceding gene: 187735233

Following gene: 187735235

Centisome position: 32.22

GC content: 55.56

Gene sequence:

>1071_bases
ATGTTTCATATTCAGACCATGTTTGTTGACAACATCCGCATATTCGCCAGGGCAGGAAAGGGAGGAAACGGGCTGGTCAG
CTTCCGAAGGGCCAAATTCGTGCCCAAGGGAGGCCCGGACGGCGGTGATGGAGGCGATGGCGGAAGCGTCATTCTGGAAG
TGGATCCGCACACGAATGACCTGCGTTCTTTTTTTTATGATCCAAAATTAATCGCCACGGACGGGGTAGGCGGACAAAGC
GCCAAGAAACATGGCAAGAACGGCAAATCCGTCATCGGGAAAGTGCCCCCCGGTACCATTATCTACCGCAGCAATGCATC
CTCCATGGCGGAGGCGACCTGGCTGGAACGGGAAGGCGAAGGCATTGAACTGGAAAAAATAGCGGATCTGACGGAAATCG
GCACCCGGTTCACGTTGTGCCAGGGCGGCCTCGGCGGCAAGGGAAACTGGCATTTCCGTTCCGCGACCAACCAGGCGCCT
ACGGAAGCCGAGATGGGAACGGAAGGGGAGGAAGGCGTCTTCTTTATGGAATTGCGCCGCATTGCGGACGCCGGGCTGGT
AGGCTACCCCAACGCGGGGAAAAGCACATTGCTGGGAGACATTTCGGAAGCCAAGCCCAAAGTAGCCAGCTATCCTTTTA
CCACGCTTCAGCCTATCATCGGAGTGGTGGAATTCGACAGCTTTCGCCGCTGCGTTGTGGCGGACATTCCCGGCATCATT
GAAGGCGCACACAACAACCGGGGCCTGGGACATGAATTCCTGCGCCACATCACGCGCTGCAAGGTGCTCGTCTTCGTTCT
GGACATGGCTGGCAGCGAAGGCCGCGACCCCATTGAAGACCTTCAAAATCTCCGCACGGAAATTAAACTGTACAGCGAAG
ACCTGGCCAAACAGCCCTGGTTTGTCGTCGCCAACAAAATGGACCTGGAAGGAGCGGAAGAAAATCTGGCTAACTTCCGC
ATGCGTTTCCCGAAAGTGGACATCATCCCCATTTCCGCGCTCAATGGAGACGGTATTTCCCGGCTCAGGAACAGGCTTGA
TGAGCTTGTAGGTTATAAATTCATCCGTTAA

Upstream 100 bases:

>100_bases
GTTCCCGTAATGATTCGAAATCCTCTTTCACGGGAAAGTCAGCGGCCTACACCGTGGAAAAACCGTGCAGCCCTGCACAT
GTCTTGCGTTTTGAAGGAAA

Downstream 100 bases:

>100_bases
CTTATTCATTCAACTTTCTTTCAACCTTTGACATGACAGCCCCTCTCTCCGTAACGACAGCTTCCGACCAGCTTCTGTGC
CGTATCGCCGGAATTGGAGA

Product: GTP-binding protein Obg/CgtA

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MFHIQTMFVDNIRIFARAGKGGNGLVSFRRAKFVPKGGPDGGDGGDGGSVILEVDPHTNDLRSFFYDPKLIATDGVGGQS
AKKHGKNGKSVIGKVPPGTIIYRSNASSMAEATWLEREGEGIELEKIADLTEIGTRFTLCQGGLGGKGNWHFRSATNQAP
TEAEMGTEGEEGVFFMELRRIADAGLVGYPNAGKSTLLGDISEAKPKVASYPFTTLQPIIGVVEFDSFRRCVVADIPGII
EGAHNNRGLGHEFLRHITRCKVLVFVLDMAGSEGRDPIEDLQNLRTEIKLYSEDLAKQPWFVVANKMDLEGAEENLANFR
MRFPKVDIIPISALNGDGISRLRNRLDELVGYKFIR

Sequences:

>Translated_356_residues
MFHIQTMFVDNIRIFARAGKGGNGLVSFRRAKFVPKGGPDGGDGGDGGSVILEVDPHTNDLRSFFYDPKLIATDGVGGQS
AKKHGKNGKSVIGKVPPGTIIYRSNASSMAEATWLEREGEGIELEKIADLTEIGTRFTLCQGGLGGKGNWHFRSATNQAP
TEAEMGTEGEEGVFFMELRRIADAGLVGYPNAGKSTLLGDISEAKPKVASYPFTTLQPIIGVVEFDSFRRCVVADIPGII
EGAHNNRGLGHEFLRHITRCKVLVFVLDMAGSEGRDPIEDLQNLRTEIKLYSEDLAKQPWFVVANKMDLEGAEENLANFR
MRFPKVDIIPISALNGDGISRLRNRLDELVGYKFIR
>Mature_356_residues
MFHIQTMFVDNIRIFARAGKGGNGLVSFRRAKFVPKGGPDGGDGGDGGSVILEVDPHTNDLRSFFYDPKLIATDGVGGQS
AKKHGKNGKSVIGKVPPGTIIYRSNASSMAEATWLEREGEGIELEKIADLTEIGTRFTLCQGGLGGKGNWHFRSATNQAP
TEAEMGTEGEEGVFFMELRRIADAGLVGYPNAGKSTLLGDISEAKPKVASYPFTTLQPIIGVVEFDSFRRCVVADIPGII
EGAHNNRGLGHEFLRHITRCKVLVFVLDMAGSEGRDPIEDLQNLRTEIKLYSEDLAKQPWFVVANKMDLEGAEENLANFR
MRFPKVDIIPISALNGDGISRLRNRLDELVGYKFIR

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=342, Percent_Identity=40.6432748538012, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI111955139, Length=363, Percent_Identity=33.3333333333333, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI111955063, Length=182, Percent_Identity=41.2087912087912, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI4758796, Length=97, Percent_Identity=37.1134020618557, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI58761500, Length=134, Percent_Identity=31.3432835820896, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789574, Length=302, Percent_Identity=45.364238410596, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1787454, Length=148, Percent_Identity=29.0540540540541, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=345, Percent_Identity=41.1594202898551, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17552324, Length=354, Percent_Identity=27.4011299435028, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17555344, Length=156, Percent_Identity=30.1282051282051, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=196, Percent_Identity=43.3673469387755, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321612, Length=88, Percent_Identity=39.7727272727273, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319281, Length=89, Percent_Identity=37.0786516853933, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129375, Length=340, Percent_Identity=40, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24585318, Length=373, Percent_Identity=33.2439678284182, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI17981711, Length=161, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 38915; Mature: 38915

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHIQTMFVDNIRIFARAGKGGNGLVSFRRAKFVPKGGPDGGDGGDGGSVILEVDPHTND
CEEEEEEEECCEEEEEECCCCCCCCEEEHHHCCCCCCCCCCCCCCCCCEEEEEECCCCHH
LRSFFYDPKLIATDGVGGQSAKKHGKNGKSVIGKVPPGTIIYRSNASSMAEATWLEREGE
HHHHHCCCEEEEECCCCCCHHHHHCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHCCCC
GIELEKIADLTEIGTRFTLCQGGLGGKGNWHFRSATNQAPTEAEMGTEGEEGVFFMELRR
CCCHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCCCHHHCCCCCCCCEEHHHHHH
IADAGLVGYPNAGKSTLLGDISEAKPKVASYPFTTLQPIIGVVEFDSFRRCVVADIPGII
HHHCCCCCCCCCCCCHHCCCHHHCCCCHHCCCCHHHHHHHHHHHHHCCCCEEECCCCHHH
EGAHNNRGLGHEFLRHITRCKVLVFVLDMAGSEGRDPIEDLQNLRTEIKLYSEDLAKQPW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCE
FVVANKMDLEGAEENLANFRMRFPKVDIIPISALNGDGISRLRNRLDELVGYKFIR
EEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFHIQTMFVDNIRIFARAGKGGNGLVSFRRAKFVPKGGPDGGDGGDGGSVILEVDPHTND
CEEEEEEEECCEEEEEECCCCCCCCEEEHHHCCCCCCCCCCCCCCCCCEEEEEECCCCHH
LRSFFYDPKLIATDGVGGQSAKKHGKNGKSVIGKVPPGTIIYRSNASSMAEATWLEREGE
HHHHHCCCEEEEECCCCCCHHHHHCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHCCCC
GIELEKIADLTEIGTRFTLCQGGLGGKGNWHFRSATNQAPTEAEMGTEGEEGVFFMELRR
CCCHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCCCHHHCCCCCCCCEEHHHHHH
IADAGLVGYPNAGKSTLLGDISEAKPKVASYPFTTLQPIIGVVEFDSFRRCVVADIPGII
HHHCCCCCCCCCCCCHHCCCHHHCCCCHHCCCCHHHHHHHHHHHHHCCCCEEECCCCHHH
EGAHNNRGLGHEFLRHITRCKVLVFVLDMAGSEGRDPIEDLQNLRTEIKLYSEDLAKQPW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCE
FVVANKMDLEGAEENLANFRMRFPKVDIIPISALNGDGISRLRNRLDELVGYKFIR
EEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA