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The map label for this gene is ybdL [H]

Identifier: 186476736

GI number: 186476736

Start: 2231820

End: 2233010

Strand: Direct

Name: ybdL [H]

Synonym: Bphy_1981

Alternate gene names: 186476736

Gene position: 2231820-2233010 (Clockwise)

Preceding gene: 186476735

Following gene: 186476738

Centisome position: 64.15

GC content: 62.38

Gene sequence:

>1191_bases
ATGAACGCACCGCACGATCCGACGACGACTACGCCTATGACCACCACACCCTCGTTCCCGTCCCGTCTGCCGAGCGTCGG
CACGACGATCTTCACCGTGATGAGCGCGCTCGCCGTCGAAAAGAACGCGGTCAATCTGGGCCAGGGCTTTCCGGATTTCG
ATTGCGATCCACGCATCGTCGATGCCGTGTCCAATGCGATGCGCGAAGGACACAATCAATACCCGCCGATGGCCGGCGTC
GCACCGCTGCGCCAGGCGATCTCCGAAAAGATCTCGAGCCTGTACGGCCGCCGCTACGACGCGACGACGGAAATCACAGT
GACGGCGGGCGCAACGCAAGCACTTCTGACGGCCATCCTGTGTGCCGTTCATCCGGGCGATGAAGTGATCGTCGTCGAAC
CGACGTACGACAGCTATCTGCCGTCGATCGAACTGGCGGGCGGCAAGCCCGTGTTCGTCACGCTCGACGCGCCCGACTAC
GCGATCCCGTTCGACAAGCTCGCTGCCGCGATCACGCCGAGGACGCGCATGATCCTGATCAACACGCCACACAACCCGAC
GGGCACTGTCTGGCGCGCGGAGGACATGAAGAAGCTCGAGGACATCGTACGCGGCACGAATGTTCTGATCCTGTCCGACG
AAGTGTATGAGCATATGGTCTACGACGGCGCGCCGCACGAGAGCGTCGCGCGCTATCCGGAACTCGCGCAGCGTAGCTTC
GTCGTGTCGAGCTTCGGCAAGACGTATCACGTGACGGGCTGGAAGGTCGGCTATGTCGCCGCGCCCGCCGCGCTGATGGC
GGAATTCCGCAAGGTGCATCAGTTCAACGTGTTCACTGTCAACACGCCCATGCAACTCGGCCTTGCGCACTACATGCAAG
ATCCGGCGCCGTATCTGAATCTGCCCGCGTTCTATCAGAAGAAGCGTGACTTCTTCCGTGCGGGTCTCGCGCAATCGCGC
TTCAAGCTGTTGCCGTGCACGGGCACGTACTTCCAGTGCGTCGACTATTCGGCCATCAGCGACATGCCCGAAGCGGAATT
CGCGCAATGGCTGACGAGCGAGATCGGCGTGGCCGCCATTCCCGTGTCGGCGTTCTATCACGAGCGGCACGAATCGGGCG
TCGTGCGCTTCTGCTTCGCGAAGAAAGAGGACACGCTCGCCACCGCGCTCGAACGGCTGGCGCGTCTCTGA

Upstream 100 bases:

>100_bases
CCGAAGAAGCCGCGCAAGCCTGACGCCCGCAAGACGCTACGCAATTCATACGCGCAGTCCCGCACACTCAACCGCCGCGC
CCTTTTTCCCTACAATCGAC

Downstream 100 bases:

>100_bases
TATGGCGCGCGCGATGTTGCGAACGAGCCCGGGTTCTTCGCCATCGCGCGCGATGCGTTGCAGCGCTGGCGCACCGGCAT
GTCGCGCACGCAGGCGGACT

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNAPHDPTTTTPMTTTPSFPSRLPSVGTTIFTVMSALAVEKNAVNLGQGFPDFDCDPRIVDAVSNAMREGHNQYPPMAGV
APLRQAISEKISSLYGRRYDATTEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLDAPDY
AIPFDKLAAAITPRTRMILINTPHNPTGTVWRAEDMKKLEDIVRGTNVLILSDEVYEHMVYDGAPHESVARYPELAQRSF
VVSSFGKTYHVTGWKVGYVAAPAALMAEFRKVHQFNVFTVNTPMQLGLAHYMQDPAPYLNLPAFYQKKRDFFRAGLAQSR
FKLLPCTGTYFQCVDYSAISDMPEAEFAQWLTSEIGVAAIPVSAFYHERHESGVVRFCFAKKEDTLATALERLARL

Sequences:

>Translated_396_residues
MNAPHDPTTTTPMTTTPSFPSRLPSVGTTIFTVMSALAVEKNAVNLGQGFPDFDCDPRIVDAVSNAMREGHNQYPPMAGV
APLRQAISEKISSLYGRRYDATTEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLDAPDY
AIPFDKLAAAITPRTRMILINTPHNPTGTVWRAEDMKKLEDIVRGTNVLILSDEVYEHMVYDGAPHESVARYPELAQRSF
VVSSFGKTYHVTGWKVGYVAAPAALMAEFRKVHQFNVFTVNTPMQLGLAHYMQDPAPYLNLPAFYQKKRDFFRAGLAQSR
FKLLPCTGTYFQCVDYSAISDMPEAEFAQWLTSEIGVAAIPVSAFYHERHESGVVRFCFAKKEDTLATALERLARL
>Mature_396_residues
MNAPHDPTTTTPMTTTPSFPSRLPSVGTTIFTVMSALAVEKNAVNLGQGFPDFDCDPRIVDAVSNAMREGHNQYPPMAGV
APLRQAISEKISSLYGRRYDATTEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLDAPDY
AIPFDKLAAAITPRTRMILINTPHNPTGTVWRAEDMKKLEDIVRGTNVLILSDEVYEHMVYDGAPHESVARYPELAQRSF
VVSSFGKTYHVTGWKVGYVAAPAALMAEFRKVHQFNVFTVNTPMQLGLAHYMQDPAPYLNLPAFYQKKRDFFRAGLAQSR
FKLLPCTGTYFQCVDYSAISDMPEAEFAQWLTSEIGVAAIPVSAFYHERHESGVVRFCFAKKEDTLATALERLARL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=409, Percent_Identity=34.2298288508557, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI169881279, Length=409, Percent_Identity=34.2298288508557, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI56713254, Length=415, Percent_Identity=33.9759036144578, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI56713256, Length=401, Percent_Identity=34.6633416458853, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI169881281, Length=407, Percent_Identity=30.4668304668305, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI4507369, Length=216, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=50.7772020725389, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1788722, Length=366, Percent_Identity=25.1366120218579, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788627, Length=221, Percent_Identity=31.6742081447964, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787710, Length=287, Percent_Identity=27.5261324041812, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787909, Length=190, Percent_Identity=27.3684210526316, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=404, Percent_Identity=34.1584158415842, Blast_Score=227, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI71994476, Length=404, Percent_Identity=34.1584158415842, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17567369, Length=399, Percent_Identity=33.3333333333333, Blast_Score=210, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17567663, Length=328, Percent_Identity=24.0853658536585, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=397, Percent_Identity=32.4937027707809, Blast_Score=199, Evalue=5e-52,
Organism=Drosophila melanogaster, GI28573069, Length=410, Percent_Identity=34.1463414634146, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24646114, Length=410, Percent_Identity=34.1463414634146, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI28573067, Length=410, Percent_Identity=34.1463414634146, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI28573065, Length=410, Percent_Identity=34.1463414634146, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI18859735, Length=207, Percent_Identity=27.0531400966184, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43682; Mature: 43682

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPHDPTTTTPMTTTPSFPSRLPSVGTTIFTVMSALAVEKNAVNLGQGFPDFDCDPRIV
CCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHH
DAVSNAMREGHNQYPPMAGVAPLRQAISEKISSLYGRRYDATTEITVTAGATQALLTAIL
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHH
CAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLDAPDYAIPFDKLAAAITPRTRMILI
HHCCCCCCEEEECCCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEE
NTPHNPTGTVWRAEDMKKLEDIVRGTNVLILSDEVYEHMVYDGAPHESVARYPELAQRSF
ECCCCCCCCEEEHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VVSSFGKTYHVTGWKVGYVAAPAALMAEFRKVHQFNVFTVNTPMQLGLAHYMQDPAPYLN
HHHHCCCEEEECCEEEHHHHCCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCCCCCC
LPAFYQKKRDFFRAGLAQSRFKLLPCTGTYFQCVDYSAISDMPEAEFAQWLTSEIGVAAI
CCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHCCHHHHCCCCHHHHHHHHHHHCCEEEE
PVSAFYHERHESGVVRFCFAKKEDTLATALERLARL
HHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNAPHDPTTTTPMTTTPSFPSRLPSVGTTIFTVMSALAVEKNAVNLGQGFPDFDCDPRIV
CCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHH
DAVSNAMREGHNQYPPMAGVAPLRQAISEKISSLYGRRYDATTEITVTAGATQALLTAIL
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHH
CAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLDAPDYAIPFDKLAAAITPRTRMILI
HHCCCCCCEEEECCCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEE
NTPHNPTGTVWRAEDMKKLEDIVRGTNVLILSDEVYEHMVYDGAPHESVARYPELAQRSF
ECCCCCCCCEEEHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VVSSFGKTYHVTGWKVGYVAAPAALMAEFRKVHQFNVFTVNTPMQLGLAHYMQDPAPYLN
HHHHCCCEEEECCEEEHHHHCCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCCCCCC
LPAFYQKKRDFFRAGLAQSRFKLLPCTGTYFQCVDYSAISDMPEAEFAQWLTSEIGVAAI
CCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHCCHHHHCCCCHHHHHHHHHHHCCEEEE
PVSAFYHERHESGVVRFCFAKKEDTLATALERLARL
HHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]