| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is fkpA [H]
Identifier: 183221014
GI number: 183221014
Start: 1700432
End: 1700818
Strand: Direct
Name: fkpA [H]
Synonym: LEPBI_I1627
Alternate gene names: 183221014
Gene position: 1700432-1700818 (Clockwise)
Preceding gene: 183221013
Following gene: 183221015
Centisome position: 47.24
GC content: 41.86
Gene sequence:
>387_bases ATGAAGCGCATGAAACAGTTATTTTTAACTCTTAGTTTTTTCTTCTTCGTAACGGGTCTTTCAGCAGAGGAACTGCTGAT TCAGGACACCAAACAAGGATTAGGCAAAGAAGCCATCCGCGGGACAACCGTTGTGGTTCATTATACTGGTAAGTTGACCA ATGGAAAGGTTTTTGATTCTTCTGTGGATCGAGGGGAACCATTTAGTTTCCAATTAGGGCAAGGCCAAGTGATCCAAGGT TGGGAACGTGGGATTATGGGCATGAAAGAAGGTGGAAAACGAAAATTGACCATTCCTCCCAAATATGGATATGGTGACAG AGCAGTTGGACCCATTCCTGCCAATTCGACTCTTGTGTTTGATGTTGAGTTAATTAAAGTTAAATAA
Upstream 100 bases:
>100_bases TGGATGACATTGGACTCACCCTACAAAAAGCCGATTTTATTCAAAAATTTGAAGAAAAGAACCAAAAAGAAGTTCCCTGG TTGTACAGAAAGAGTGTATA
Downstream 100 bases:
>100_bases ATGATTGATCCGATTTCCAAAGGTATCGATGACTTTGGCAACAGTTTGTTGCAAGCACTGAATAATGTACAGGGTATCTT TGGAAAGGAACTTTCCGTTG
Product: FK506-binding protein
Products: NA
Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]
Number of amino acids: Translated: 128; Mature: 128
Protein sequence:
>128_residues MKRMKQLFLTLSFFFFVTGLSAEELLIQDTKQGLGKEAIRGTTVVVHYTGKLTNGKVFDSSVDRGEPFSFQLGQGQVIQG WERGIMGMKEGGKRKLTIPPKYGYGDRAVGPIPANSTLVFDVELIKVK
Sequences:
>Translated_128_residues MKRMKQLFLTLSFFFFVTGLSAEELLIQDTKQGLGKEAIRGTTVVVHYTGKLTNGKVFDSSVDRGEPFSFQLGQGQVIQG WERGIMGMKEGGKRKLTIPPKYGYGDRAVGPIPANSTLVFDVELIKVK >Mature_128_residues MKRMKQLFLTLSFFFFVTGLSAEELLIQDTKQGLGKEAIRGTTVVVHYTGKLTNGKVFDSSVDRGEPFSFQLGQGQVIQG WERGIMGMKEGGKRKLTIPPKYGYGDRAVGPIPANSTLVFDVELIKVK
Specific function: PPIases accelerate the folding of proteins [H]
COG id: COG0545
COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1
Gene ontology:
Cell location: Periplasmic Protein [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase FKBP-type domain [H]
Homologues:
Organism=Homo sapiens, GI206725530, Length=90, Percent_Identity=54.4444444444444, Blast_Score=105, Evalue=9e-24, Organism=Homo sapiens, GI17149844, Length=90, Percent_Identity=54.4444444444444, Blast_Score=105, Evalue=9e-24, Organism=Homo sapiens, GI17149842, Length=90, Percent_Identity=54.4444444444444, Blast_Score=105, Evalue=9e-24, Organism=Homo sapiens, GI17149836, Length=90, Percent_Identity=56.6666666666667, Blast_Score=100, Evalue=2e-22, Organism=Homo sapiens, GI4503725, Length=90, Percent_Identity=56.6666666666667, Blast_Score=100, Evalue=2e-22, Organism=Homo sapiens, GI224809331, Length=89, Percent_Identity=52.8089887640449, Blast_Score=95, Evalue=2e-20, Organism=Homo sapiens, GI224809329, Length=89, Percent_Identity=52.8089887640449, Blast_Score=93, Evalue=5e-20, Organism=Homo sapiens, GI224809327, Length=89, Percent_Identity=52.8089887640449, Blast_Score=93, Evalue=5e-20, Organism=Homo sapiens, GI4758384, Length=89, Percent_Identity=52.8089887640449, Blast_Score=93, Evalue=5e-20, Organism=Homo sapiens, GI4758380, Length=90, Percent_Identity=51.1111111111111, Blast_Score=91, Evalue=2e-19, Organism=Homo sapiens, GI4503729, Length=100, Percent_Identity=48, Blast_Score=89, Evalue=1e-18, Organism=Homo sapiens, GI7706131, Length=110, Percent_Identity=38.1818181818182, Blast_Score=78, Evalue=2e-15, Organism=Homo sapiens, GI33469985, Length=80, Percent_Identity=43.75, Blast_Score=78, Evalue=2e-15, Organism=Homo sapiens, GI8923659, Length=91, Percent_Identity=41.7582417582418, Blast_Score=78, Evalue=2e-15, Organism=Homo sapiens, GI150010552, Length=114, Percent_Identity=41.2280701754386, Blast_Score=76, Evalue=1e-14, Organism=Homo sapiens, GI192448443, Length=93, Percent_Identity=43.010752688172, Blast_Score=75, Evalue=1e-14, Organism=Homo sapiens, GI4503727, Length=97, Percent_Identity=36.0824742268041, Blast_Score=73, Evalue=6e-14, Organism=Homo sapiens, GI31317231, Length=144, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=2e-12, Organism=Homo sapiens, GI206725547, Length=143, Percent_Identity=32.8671328671329, Blast_Score=67, Evalue=5e-12, Organism=Escherichia coli, GI1789745, Length=104, Percent_Identity=51.9230769230769, Blast_Score=86, Evalue=5e-19, Organism=Escherichia coli, GI87082390, Length=98, Percent_Identity=50, Blast_Score=84, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17540882, Length=132, Percent_Identity=42.4242424242424, Blast_Score=101, Evalue=8e-23, Organism=Caenorhabditis elegans, GI71993519, Length=90, Percent_Identity=55.5555555555556, Blast_Score=99, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17561782, Length=102, Percent_Identity=50.9803921568627, Blast_Score=95, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17561778, Length=97, Percent_Identity=43.298969072165, Blast_Score=78, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17506169, Length=93, Percent_Identity=38.7096774193548, Blast_Score=70, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17506167, Length=93, Percent_Identity=38.7096774193548, Blast_Score=70, Evalue=4e-13, Organism=Caenorhabditis elegans, GI71993555, Length=75, Percent_Identity=44, Blast_Score=65, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17561780, Length=93, Percent_Identity=36.5591397849462, Blast_Score=64, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6323482, Length=104, Percent_Identity=50.9615384615385, Blast_Score=109, Evalue=2e-25, Organism=Saccharomyces cerevisiae, GI6323566, Length=104, Percent_Identity=50, Blast_Score=106, Evalue=1e-24, Organism=Saccharomyces cerevisiae, GI6324194, Length=89, Percent_Identity=59.5505617977528, Blast_Score=102, Evalue=2e-23, Organism=Saccharomyces cerevisiae, GI6320727, Length=131, Percent_Identity=45.8015267175573, Blast_Score=102, Evalue=2e-23, Organism=Drosophila melanogaster, GI281363946, Length=132, Percent_Identity=44.6969696969697, Blast_Score=111, Evalue=1e-25, Organism=Drosophila melanogaster, GI17352457, Length=132, Percent_Identity=44.6969696969697, Blast_Score=111, Evalue=1e-25, Organism=Drosophila melanogaster, GI21356629, Length=130, Percent_Identity=43.0769230769231, Blast_Score=97, Evalue=2e-21, Organism=Drosophila melanogaster, GI24655568, Length=90, Percent_Identity=52.2222222222222, Blast_Score=96, Evalue=8e-21, Organism=Drosophila melanogaster, GI24647110, Length=103, Percent_Identity=52.4271844660194, Blast_Score=94, Evalue=2e-20, Organism=Drosophila melanogaster, GI24583150, Length=100, Percent_Identity=45, Blast_Score=88, Evalue=1e-18,
Paralogues:
None
Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001179 [H]
Pfam domain/function: PF00254 FKBP_C [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 14173; Mature: 14173
Theoretical pI: Translated: 10.34; Mature: 10.34
Prosite motif: PS50059 FKBP_PPIASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRMKQLFLTLSFFFFVTGLSAEELLIQDTKQGLGKEAIRGTTVVVHYTGKLTNGKVFDS CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECCCCCCEEECC SVDRGEPFSFQLGQGQVIQGWERGIMGMKEGGKRKLTIPPKYGYGDRAVGPIPANSTLVF CCCCCCCEEEECCCCCEECCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEE DVELIKVK EEEEEEEC >Mature Secondary Structure MKRMKQLFLTLSFFFFVTGLSAEELLIQDTKQGLGKEAIRGTTVVVHYTGKLTNGKVFDS CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECCCCCCEEECC SVDRGEPFSFQLGQGQVIQGWERGIMGMKEGGKRKLTIPPKYGYGDRAVGPIPANSTLVF CCCCCCCEEEECCCCCEECCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEE DVELIKVK EEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10761919 [H]