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The map label for this gene is bcd [H]

Identifier: 183220535

GI number: 183220535

Start: 1186317

End: 1187501

Strand: Direct

Name: bcd [H]

Synonym: LEPBI_I1138

Alternate gene names: 183220535

Gene position: 1186317-1187501 (Clockwise)

Preceding gene: 183220533

Following gene: 183220536

Centisome position: 32.96

GC content: 43.12

Gene sequence:

>1185_bases
ATGAGTATTGTTACGACCAAAAAATCTTCTTTTGATTTATTCAATCCAACAGAAGACCATCTCTCCCTACGACAATCCGT
TGCTTCCTTTGCAGAACGTGAACTAGACGAACAAGCAAAAGAAAATGATGAAACAGAATCTTTTAATCATATGTTATTCA
AACGCCTCGGTTCCGAACTGGGAATCTTTGGGATCACAGTACCTGAAGAAGATGGTGGGCATGGGCTTGATCCACTTGCA
TCCGTCATCATCCATGAAGAGATGAGTCGTTTTGATCCAGGGTTCACACTTTCTTATTTAGCACACGAAGTCCTCTTTGT
GAATAATTTCTTTTATAGTTCGAATGCATCGCAACGCAGTCGTTACCTGAGTAAGGTGATCACTGGGGAATGGATCGGTG
GAATGGGAATGACGGAACCTGGGGCAGGGACTGATGTTCTGGGAATGACAACCCAAGCCGTCAAAAAAGGAGATCGATAT
ATCATCAATGGAGTGAAACAATACATCACAAATGGTTCTGTCGGCCAGGTTTTTGTATTGTATACAAAGTTAGACAAAAA
CGCGAAAAAGATGACCTCCTTTGTGGTCGAGTCGTCGTACAAGGGTTTTTCGGTCGGAAAAAAAGAAGAAAAGATGGGAA
TGCGATCCTCTCCTACCACACAATTAGTCTTTGAAGATATGGAAGTTCCTGAAGAGAATTTACTTGGCGTAGAAAATGGA
GCGATCACACATATGATGCGCAATTTAGAAATCGAACGAGTGACTCTTGCGGCCCAATCTTTGGGAATTGCACGTCGTTG
TGTGGACATTATGTGTGATTATACAGTTCGCCACAGAGAAGCCTTTGGAAAAAAACTAATGGAATTTGGTCAAATCCAAA
GGTTAATTGCGGAATCTTATGCGGATTACCAAGCGGCAAGGGCGCTTGTCTACCAAGTGGCAAGTGAACTTGGTCCCGAT
GTAAGAAACTCGCTTGGTGCAGCATCCGCTAAACTTGTAGCTACCCAAATGGCAGAACGTGTTTCTAGGAACGCCATACA
GGTATTAGGTGGATATGGTTACTGCCGTGAATACCCTGTCGAAAGACTCCACAGAGATGCCATTCTTTTGAGCATTGGTG
GTGGGACAAACGAAGCCATGCAAAAAAACATCGCAAGTGATCTAAAAAAACTTTGGTCGGAGTGA

Upstream 100 bases:

>100_bases
TTTTAGTCGTTCGTTTTTGAAACAAAATGATCCAAACGGGTGCATTTCCCTCTGATTTTTTCGTTTACAGTTTCAGGAAA
AGTACGGAAAAATCTTCTCT

Downstream 100 bases:

>100_bases
ATTGAAAAAAAATCGTTCTGATCAAATCACAAAAATCATTTGGACATAAAATCTTTTTCCCATTCGATTTTCACATCCAG
TCTACTGGATAGATGGAAAC

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSIVTTKKSSFDLFNPTEDHLSLRQSVASFAERELDEQAKENDETESFNHMLFKRLGSELGIFGITVPEEDGGHGLDPLA
SVIIHEEMSRFDPGFTLSYLAHEVLFVNNFFYSSNASQRSRYLSKVITGEWIGGMGMTEPGAGTDVLGMTTQAVKKGDRY
IINGVKQYITNGSVGQVFVLYTKLDKNAKKMTSFVVESSYKGFSVGKKEEKMGMRSSPTTQLVFEDMEVPEENLLGVENG
AITHMMRNLEIERVTLAAQSLGIARRCVDIMCDYTVRHREAFGKKLMEFGQIQRLIAESYADYQAARALVYQVASELGPD
VRNSLGAASAKLVATQMAERVSRNAIQVLGGYGYCREYPVERLHRDAILLSIGGGTNEAMQKNIASDLKKLWSE

Sequences:

>Translated_394_residues
MSIVTTKKSSFDLFNPTEDHLSLRQSVASFAERELDEQAKENDETESFNHMLFKRLGSELGIFGITVPEEDGGHGLDPLA
SVIIHEEMSRFDPGFTLSYLAHEVLFVNNFFYSSNASQRSRYLSKVITGEWIGGMGMTEPGAGTDVLGMTTQAVKKGDRY
IINGVKQYITNGSVGQVFVLYTKLDKNAKKMTSFVVESSYKGFSVGKKEEKMGMRSSPTTQLVFEDMEVPEENLLGVENG
AITHMMRNLEIERVTLAAQSLGIARRCVDIMCDYTVRHREAFGKKLMEFGQIQRLIAESYADYQAARALVYQVASELGPD
VRNSLGAASAKLVATQMAERVSRNAIQVLGGYGYCREYPVERLHRDAILLSIGGGTNEAMQKNIASDLKKLWSE
>Mature_393_residues
SIVTTKKSSFDLFNPTEDHLSLRQSVASFAERELDEQAKENDETESFNHMLFKRLGSELGIFGITVPEEDGGHGLDPLAS
VIIHEEMSRFDPGFTLSYLAHEVLFVNNFFYSSNASQRSRYLSKVITGEWIGGMGMTEPGAGTDVLGMTTQAVKKGDRYI
INGVKQYITNGSVGQVFVLYTKLDKNAKKMTSFVVESSYKGFSVGKKEEKMGMRSSPTTQLVFEDMEVPEENLLGVENGA
ITHMMRNLEIERVTLAAQSLGIARRCVDIMCDYTVRHREAFGKKLMEFGQIQRLIAESYADYQAARALVYQVASELGPDV
RNSLGAASAKLVATQMAERVSRNAIQVLGGYGYCREYPVERLHRDAILLSIGGGTNEAMQKNIASDLKKLWSE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=368, Percent_Identity=39.4021739130435, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI226958414, Length=364, Percent_Identity=38.4615384615385, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=34.0425531914894, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI187960098, Length=370, Percent_Identity=34.3243243243243, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI4557231, Length=370, Percent_Identity=34.3243243243243, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI21361497, Length=365, Percent_Identity=33.1506849315069, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI4501859, Length=377, Percent_Identity=30.7692307692308, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI4501857, Length=383, Percent_Identity=30.2872062663185, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI7656849, Length=394, Percent_Identity=29.6954314720812, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI4557235, Length=373, Percent_Identity=30.2949061662198, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI76496475, Length=373, Percent_Identity=30.2949061662198, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI7669494, Length=379, Percent_Identity=24.5382585751979, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4503943, Length=379, Percent_Identity=24.5382585751979, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI48976061, Length=280, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI211971008, Length=280, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI38505218, Length=284, Percent_Identity=25.3521126760563, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI87081958, Length=335, Percent_Identity=31.3432835820896, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786223, Length=331, Percent_Identity=26.5861027190332, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082384, Length=265, Percent_Identity=25.2830188679245, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=385, Percent_Identity=37.6623376623377, Blast_Score=257, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI17570075, Length=380, Percent_Identity=33.1578947368421, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17569725, Length=378, Percent_Identity=33.5978835978836, Blast_Score=212, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17534899, Length=380, Percent_Identity=32.8947368421053, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=32.620320855615, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17508101, Length=375, Percent_Identity=32.5333333333333, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI71985184, Length=354, Percent_Identity=32.2033898305085, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=33.1550802139037, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71990804, Length=306, Percent_Identity=34.3137254901961, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17533517, Length=368, Percent_Identity=30.4347826086957, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=31.283422459893, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI71985192, Length=301, Percent_Identity=30.8970099667774, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=32.4561403508772, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17534353, Length=351, Percent_Identity=28.2051282051282, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71982178, Length=281, Percent_Identity=26.3345195729537, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=335, Percent_Identity=26.865671641791, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355753, Length=386, Percent_Identity=38.860103626943, Blast_Score=261, Evalue=5e-70,
Organism=Drosophila melanogaster, GI21356377, Length=379, Percent_Identity=34.3007915567282, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=31.6622691292876, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24660351, Length=391, Percent_Identity=32.4808184143223, Blast_Score=197, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=33.9522546419098, Blast_Score=197, Evalue=9e-51,
Organism=Drosophila melanogaster, GI281363737, Length=337, Percent_Identity=30.5637982195846, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19920834, Length=359, Percent_Identity=28.9693593314763, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 43803; Mature: 43672

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVTTKKSSFDLFNPTEDHLSLRQSVASFAERELDEQAKENDETESFNHMLFKRLGSEL
CCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
GIFGITVPEEDGGHGLDPLASVIIHEEMSRFDPGFTLSYLAHEVLFVNNFFYSSNASQRS
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
RYLSKVITGEWIGGMGMTEPGAGTDVLGMTTQAVKKGDRYIINGVKQYITNGSVGQVFVL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEE
YTKLDKNAKKMTSFVVESSYKGFSVGKKEEKMGMRSSPTTQLVFEDMEVPEENLLGVENG
EEECCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCHHHCCCCCCH
AITHMMRNLEIERVTLAAQSLGIARRCVDIMCDYTVRHREAFGKKLMEFGQIQRLIAESY
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADYQAARALVYQVASELGPDVRNSLGAASAKLVATQMAERVSRNAIQVLGGYGYCREYPV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCH
ERLHRDAILLSIGGGTNEAMQKNIASDLKKLWSE
HHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIVTTKKSSFDLFNPTEDHLSLRQSVASFAERELDEQAKENDETESFNHMLFKRLGSEL
CCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
GIFGITVPEEDGGHGLDPLASVIIHEEMSRFDPGFTLSYLAHEVLFVNNFFYSSNASQRS
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
RYLSKVITGEWIGGMGMTEPGAGTDVLGMTTQAVKKGDRYIINGVKQYITNGSVGQVFVL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEE
YTKLDKNAKKMTSFVVESSYKGFSVGKKEEKMGMRSSPTTQLVFEDMEVPEENLLGVENG
EEECCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCHHHCCCCCCH
AITHMMRNLEIERVTLAAQSLGIARRCVDIMCDYTVRHREAFGKKLMEFGQIQRLIAESY
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADYQAARALVYQVASELGPDVRNSLGAASAKLVATQMAERVSRNAIQVLGGYGYCREYPV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCH
ERLHRDAILLSIGGGTNEAMQKNIASDLKKLWSE
HHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]