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The map label for this gene is dsbD [C]

Identifier: 183220342

GI number: 183220342

Start: 970934

End: 971755

Strand: Reverse

Name: dsbD [C]

Synonym: LEPBI_I0938

Alternate gene names: 183220342

Gene position: 971755-970934 (Counterclockwise)

Preceding gene: 183220345

Following gene: 183220337

Centisome position: 27.0

GC content: 33.7

Gene sequence:

>822_bases
ATGTTTCGATTTAGTTTACTCCTCATCTCTTTCCTATTTGGTTCGATTCTTTCGGCTGACTCCAATTGGGGTAATTCCAT
CCAGAAGGGATTTGAAACCGCCAAACAAGAAAAAAAATTCATCATCGTCGATGTGTTTGCAGATTGGTGTACCTATTGTA
TGGTTTTGGAAAAAGAGATATTCCCTGATCCTGAGGTAAGTCGTATTTTAGACCAATTTGTACGTGTTAGATTAGATGGA
GAAGAATTCCCCAATTTGCGGAAAAAATACAATGTAGAAGGTTATCCCACGATTCTGTTTTTAGATGGAGAGGGAAATTT
TGTGACAAAAATCACAGGACTCGCAACGAAAGAAGATATATTGATCCTTTCCAAAAGAATCTTACAAGAACCAAATTTAG
AATCTTTTTTGAAAACAGAGATGAGAAAGGATAAAGAAAACCCAAACTTACATTTTCGATTGGGTTTATTGTACTTTCAA
TCTAAAGAATATACAAAAGCAGAAGAACAATTCATCTCTTCCATTCAAAAGTCAAAACAACTCCCTATCGTGAAAGAAAA
TTCTTATTTTAATTTAAACCTAATTCGATCCGTCAATGGACCAAAAGAATTAGCAGTAACTTCTTGGAAAGAATTCATCC
AACTTTATCCAAATTCAAAACGATTGATCACAGCTAAATTGTATTATGGAATCAGTTTGAAAGAAAGTGGCGACTTCAAA
CATGCAAAGACGATCTTAAAAGAAATCCAACCAAAACTAGAATCCGAATCAGACCAATTGATTTGTAAAGAAACCTTAGA
ACAAATCGAAAAAGGATTTTAA

Upstream 100 bases:

>100_bases
TTTCGTTTGCCTTCTAACTACCATGGAAACGGCCCTTTCTATTTTCAAAAAGCGAAAATTGGTTGTGGCTTCACCTCGAA
TTAGGGTAGAATCAGATTGA

Downstream 100 bases:

>100_bases
AGCAAAATGTAAGTTCCGGCAAACGAATGTTTGCCGGGAAACTTTACCGATTCCCGATCGAATAGTAAGTAAACCCAATT
TCTTGCATCAAATTTGGTTT

Product: putative protein-disulfide reductase

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: Thiol Disulfide Interchange Protein DsbD Like Protein; Thiol-Disulfide Interchange Like Protein; Peptidylprolyl Isomerase FKBP-Type; Thioredoxin Domain-Containing Protein; TPR Repeat-Containing Protein; Protein-Disulfide Reductase; ThiolDisulfide Interchange Protein; Thioredoxin Domain; Disulphide-Isomerase; Thiol-Disulfide Interchange Protein DsbD-Like Protein

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MFRFSLLLISFLFGSILSADSNWGNSIQKGFETAKQEKKFIIVDVFADWCTYCMVLEKEIFPDPEVSRILDQFVRVRLDG
EEFPNLRKKYNVEGYPTILFLDGEGNFVTKITGLATKEDILILSKRILQEPNLESFLKTEMRKDKENPNLHFRLGLLYFQ
SKEYTKAEEQFISSIQKSKQLPIVKENSYFNLNLIRSVNGPKELAVTSWKEFIQLYPNSKRLITAKLYYGISLKESGDFK
HAKTILKEIQPKLESESDQLICKETLEQIEKGF

Sequences:

>Translated_273_residues
MFRFSLLLISFLFGSILSADSNWGNSIQKGFETAKQEKKFIIVDVFADWCTYCMVLEKEIFPDPEVSRILDQFVRVRLDG
EEFPNLRKKYNVEGYPTILFLDGEGNFVTKITGLATKEDILILSKRILQEPNLESFLKTEMRKDKENPNLHFRLGLLYFQ
SKEYTKAEEQFISSIQKSKQLPIVKENSYFNLNLIRSVNGPKELAVTSWKEFIQLYPNSKRLITAKLYYGISLKESGDFK
HAKTILKEIQPKLESESDQLICKETLEQIEKGF
>Mature_273_residues
MFRFSLLLISFLFGSILSADSNWGNSIQKGFETAKQEKKFIIVDVFADWCTYCMVLEKEIFPDPEVSRILDQFVRVRLDG
EEFPNLRKKYNVEGYPTILFLDGEGNFVTKITGLATKEDILILSKRILQEPNLESFLKTEMRKDKENPNLHFRLGLLYFQ
SKEYTKAEEQFISSIQKSKQLPIVKENSYFNLNLIRSVNGPKELAVTSWKEFIQLYPNSKRLITAKLYYGISLKESGDFK
HAKTILKEIQPKLESESDQLICKETLEQIEKGF

Specific function: Required To Facilitate The Formation Of Correct Disulfide Bonds In Some Periplasmic Proteins And For The Assembly Of The Periplasmic C-Type Cytochromes. Acts By Transferring Electrons From Cytoplasmic Thioredoxin To The Periplasm, Thereby Maintaining The

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 31769; Mature: 31769

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRFSLLLISFLFGSILSADSNWGNSIQKGFETAKQEKKFIIVDVFADWCTYCMVLEKEI
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHC
FPDPEVSRILDQFVRVRLDGEEFPNLRKKYNVEGYPTILFLDGEGNFVTKITGLATKEDI
CCCCHHHHHHHHHHHEEECCHHCCCHHHHCCCCCCCEEEEECCCCCEEEEEECCCCHHHH
LILSKRILQEPNLESFLKTEMRKDKENPNLHFRLGLLYFQSKEYTKAEEQFISSIQKSKQ
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHCC
LPIVKENSYFNLNLIRSVNGPKELAVTSWKEFIQLYPNSKRLITAKLYYGISLKESGDFK
CCEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCHH
HAKTILKEIQPKLESESDQLICKETLEQIEKGF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFRFSLLLISFLFGSILSADSNWGNSIQKGFETAKQEKKFIIVDVFADWCTYCMVLEKEI
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHC
FPDPEVSRILDQFVRVRLDGEEFPNLRKKYNVEGYPTILFLDGEGNFVTKITGLATKEDI
CCCCHHHHHHHHHHHEEECCHHCCCHHHHCCCCCCCEEEEECCCCCEEEEEECCCCHHHH
LILSKRILQEPNLESFLKTEMRKDKENPNLHFRLGLLYFQSKEYTKAEEQFISSIQKSKQ
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHCC
LPIVKENSYFNLNLIRSVNGPKELAVTSWKEFIQLYPNSKRLITAKLYYGISLKESGDFK
CCEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCHH
HAKTILKEIQPKLESESDQLICKETLEQIEKGF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA