Click here to switch to the map view.

The map label for this gene is hmuO [H]

Identifier: 183220082

GI number: 183220082

Start: 673067

End: 673747

Strand: Reverse

Name: hmuO [H]

Synonym: LEPBI_I0669

Alternate gene names: 183220082

Gene position: 673747-673067 (Counterclockwise)

Preceding gene: 183220083

Following gene: 183220081

Centisome position: 18.72

GC content: 40.68

Gene sequence:

>681_bases
ATGTCAGTTGCAATGATGTTACGAGAAGGGACGGCGCAAAAACATGAGGAAACTGAAAAAGTTCCCTATATCCGTGCCAT
TTTCCGTGGGGGACTCGATGCCCAAACATATACTTACCAATTAGAAAGCCTTCTTGCGGTCTACCGAGTGATGGAAGAAC
TTTACCGCCAAAACAAAGACAATCCCATCCTTTCTAAATTATACTTCCCCAGTTTATTTCGAGAAAAGTCCTTACAAGAA
GACATCGTTACCTTCCAAAAAAAGTTTGGAACAAAACTCAGAGGCGAAGTTTCCAAGGCCACACAAAACTACATCAACCA
CATCCAAACCACGGCCCAATCCAAACCAGAACTTCTGGTAGCACAAGCTTACGTGCGTTATTTGGGAGATTTATCCGGTG
GCCAAGCGATCAAAAAAGTAGTGGCAAAAACCTTTGGTCTCGAGGGAAATGAAGGAACTGCTTTTTATGAATTCCCAGAG
ATCGAAGACCTAATGGCGTTTAAAGGAATTTACCGTCAGAATTTGGATACTTTGCCATTAAATGATTCGCAAAAAGCAGA
ACTATTAGAAGAAGCCAAAACAACGTTTGATTTAAACAAATTTTTGTTCATCGAACTCGATTCCGATTTAAAAGAAAATA
TCGGAATGGAACGTTACCAAACTCTTCTGCCAGCAGGTTAA

Upstream 100 bases:

>100_bases
ATCAGGAAGACTCCCTATAATTCTCTTTGACAGTTCCCCTGATTGTCAGGGTAGTGTCATATATGAGATTGATTCTCACA
TACAGAGATTAGGAGCCATT

Downstream 100 bases:

>100_bases
TTTTTGGGATTCCCGTATACACTCGTAACACTTGTATTTTTATCGATGTTGCCGGTCACGATGATTGTGCCGGTAGTCAA
AGACATTGTAAAGGATCGTT

Product: Heme oxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSVAMMLREGTAQKHEETEKVPYIRAIFRGGLDAQTYTYQLESLLAVYRVMEELYRQNKDNPILSKLYFPSLFREKSLQE
DIVTFQKKFGTKLRGEVSKATQNYINHIQTTAQSKPELLVAQAYVRYLGDLSGGQAIKKVVAKTFGLEGNEGTAFYEFPE
IEDLMAFKGIYRQNLDTLPLNDSQKAELLEEAKTTFDLNKFLFIELDSDLKENIGMERYQTLLPAG

Sequences:

>Translated_226_residues
MSVAMMLREGTAQKHEETEKVPYIRAIFRGGLDAQTYTYQLESLLAVYRVMEELYRQNKDNPILSKLYFPSLFREKSLQE
DIVTFQKKFGTKLRGEVSKATQNYINHIQTTAQSKPELLVAQAYVRYLGDLSGGQAIKKVVAKTFGLEGNEGTAFYEFPE
IEDLMAFKGIYRQNLDTLPLNDSQKAELLEEAKTTFDLNKFLFIELDSDLKENIGMERYQTLLPAG
>Mature_225_residues
SVAMMLREGTAQKHEETEKVPYIRAIFRGGLDAQTYTYQLESLLAVYRVMEELYRQNKDNPILSKLYFPSLFREKSLQED
IVTFQKKFGTKLRGEVSKATQNYINHIQTTAQSKPELLVAQAYVRYLGDLSGGQAIKKVVAKTFGLEGNEGTAFYEFPEI
EDLMAFKGIYRQNLDTLPLNDSQKAELLEEAKTTFDLNKFLFIELDSDLKENIGMERYQTLLPAG

Specific function: Catalyzes the opening of the heme ring with the release of iron. Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae [H]

COG id: COG5398

COG function: function code P; Heme oxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme oxygenase family [H]

Homologues:

Organism=Homo sapiens, GI187761311, Length=206, Percent_Identity=37.378640776699, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI187761309, Length=206, Percent_Identity=37.378640776699, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI187761307, Length=206, Percent_Identity=37.378640776699, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI8051608, Length=206, Percent_Identity=37.378640776699, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI4504437, Length=204, Percent_Identity=35.2941176470588, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002051
- InterPro:   IPR016053
- InterPro:   IPR016084
- InterPro:   IPR018207 [H]

Pfam domain/function: PF01126 Heme_oxygenase [H]

EC number: =1.14.99.3 [H]

Molecular weight: Translated: 25893; Mature: 25762

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVAMMLREGTAQKHEETEKVPYIRAIFRGGLDAQTYTYQLESLLAVYRVMEELYRQNKD
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NPILSKLYFPSLFREKSLQEDIVTFQKKFGTKLRGEVSKATQNYINHIQTTAQSKPELLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AQAYVRYLGDLSGGQAIKKVVAKTFGLEGNEGTAFYEFPEIEDLMAFKGIYRQNLDTLPL
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCC
NDSQKAELLEEAKTTFDLNKFLFIELDSDLKENIGMERYQTLLPAG
CCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHCCHHHHHHHCCCC
>Mature Secondary Structure 
SVAMMLREGTAQKHEETEKVPYIRAIFRGGLDAQTYTYQLESLLAVYRVMEELYRQNKD
CHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NPILSKLYFPSLFREKSLQEDIVTFQKKFGTKLRGEVSKATQNYINHIQTTAQSKPELLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AQAYVRYLGDLSGGQAIKKVVAKTFGLEGNEGTAFYEFPEIEDLMAFKGIYRQNLDTLPL
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCC
NDSQKAELLEEAKTTFDLNKFLFIELDSDLKENIGMERYQTLLPAG
CCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]