Click here to switch to the map view.

The map label for this gene is ydiD [C]

Identifier: 183219534

GI number: 183219534

Start: 108163

End: 110088

Strand: Direct

Name: ydiD [C]

Synonym: LEPBI_I0107

Alternate gene names: 183219534

Gene position: 108163-110088 (Clockwise)

Preceding gene: 183219533

Following gene: 183219535

Centisome position: 3.0

GC content: 33.59

Gene sequence:

>1926_bases
ATGAAAGTTCCGAGTCTCAGTAAATTGACAATATTTCACTTGCTCCAAGAAGGAAGACGTCTTTACGGCGATCTTCCTGT
GCAAAGTTTTAAAGATCATAAAAAAGAGTACCAAAACATTTCTTACGAAGAATTTGTTTCTAATGTTACTATCATTTCTA
AGGCACTGATCCACTTAAATACAAATGCTGGTGATAGAATTGGAATCATAGCAGATGTAGGTCACCAATGGTTACAGGTT
AGCATGGCAATCACTAGCATCGGGTGTGTTGATGTACCAAGAGGAACAGACGCTACACAAGATGACATAGGGTATATTCT
AAATCATGCGAATTGTAAAATTGTTTTTATAGAGAATGAAAAGGCACTTAATAAATTTCTCCCTGAATTAAGAAAATTAA
ATCTACAAATCATTATTCTTTTTGGTGAATCGAAACCTGATTCGATGGAGATTCAGTGTCCTATTATAAATTTCACTGAT
TTAAAAATTTATTCGCAGGAAATAGAAGATAAAACCTATCAAGAAATTGGTGAAGAAATTCAAGAAGAAGATTTAGCAAC
GATTATTTATACTTCTGGAACCACAGGTAAACCAAAAGGTGTGATGTTAACACATGGAAGTATCCTTTTTGAGATCCAAG
CCTTAGTTTCTGAGTTTAGAAAAACGGGCGTTAAAGTAGGTGAAGGTGATGTGACATTAGGTTTTTTGCCACCTTGGCAT
AGTGGTGAGAGAATTTTTGAAACCATTTGTTTTTATTCGGGGATAAAAATTGCTTTTACGAGTGTGCCAGAACTAGGGAA
AGATTTGGCAAAGGCAAAACCTACGATTCTTTTTACTGTTCCTAGAGTTTGGGAAAGTTTTTATGATAAAATTAAAGATA
CCATTCAAAAAAGTCATTGGATCAAAAAATATTTTTTAAAGTTATTAGTCTGGAATTCAGTTCAATTTTCTATCACATAT
GATAAAGCATTTGATCGTATTCCAAGATTAATTACTCCAAAAACTTTTTCATTATACATACTTCAAATTTTCAATTGCAT
CAAATTGATGATTTATCTCCCATTATTACCCATCTCAAAATTTGTTTTATCAAAAATACTTTCTGTGTTAGGTGGGAGGC
TACGGTATGCATTTGCTGGTGCAGGTGCCTTACAAGCAGAAGTGGATCGATTTATGTATGCGATTGGAATGCCAATCTTA
GAAGTATATGGTATGACAGAAAATTCTGGTGTATCCACCATTCGTCACTACAATGATTTTTCTGTTGGAAATGTGGGAAA
ACCAATCCAAGGTGTTACGATCAAATTAATTGATGAATTTGGTAAAGAGATTAGAAAACCAGGAATCAAAGGTGTCGCTC
TTCACCATGGTCGGCACAATATGAAAGGGTATTACTTAGAAGAAGAAAAAACGAAAGCAGTTTTAACGGATGATCGTTGG
TTAAATTCTGGTGATCTATTGGTTTGGACTACACAAGGAAATTTGAAATTTGCAGGTAGAGCGAAAGATACCATTGTTTT
ATCGGGTGGTGAAAATGTGGAACCGGAACCAATTGAGATTTGCCTCAAACAGAGTGATTACATTGACCAAGCGGTTGTTG
TCGGCCAAGATAAAAAAACTCTTTCAGCATTGATTATACTCAACTTAGAAAAAGTTGAAACTTATCTAAAAGAACAATCA
ATCAATATGAATTTAAAAAATTCTATTTATCAAGAAGTGGAGATCATTCAAAAATTAATCAGAAACGAAGTGAAACATTT
TGTTTCGGATAAAAATGGATTTAAATCCTTTGAACGTATTTCAAATGTTTATATCTTACAAAATCCTTTTGTTGTCCATG
ACGAACTGACACAAACACAAAAAGTGAAACGAAACCGGGTGCAAGAAAAGTATCAGAAAGAAATAGAATCAATGTATCGG
AAATAA

Upstream 100 bases:

>100_bases
TCATGAGTAGTTTCTTTTTGGGTTTGAATCGTTTTTTGCCTCAAAAATTAAAAGATAAAATTCTACTCGATCACATGAAT
ATCAATGTATAGGAAGAAGA

Downstream 100 bases:

>100_bases
AAGGATTTTAAATGAAAACCTATCATTCATGGAAATTGGATATCGAAGATCGTATTGCAACTTTGACTCTTCACACAAAT
GATTTGAATGTGATGGATAT

Product: long-chain-fatty-acid--CoA ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 641; Mature: 641

Protein sequence:

>641_residues
MKVPSLSKLTIFHLLQEGRRLYGDLPVQSFKDHKKEYQNISYEEFVSNVTIISKALIHLNTNAGDRIGIIADVGHQWLQV
SMAITSIGCVDVPRGTDATQDDIGYILNHANCKIVFIENEKALNKFLPELRKLNLQIIILFGESKPDSMEIQCPIINFTD
LKIYSQEIEDKTYQEIGEEIQEEDLATIIYTSGTTGKPKGVMLTHGSILFEIQALVSEFRKTGVKVGEGDVTLGFLPPWH
SGERIFETICFYSGIKIAFTSVPELGKDLAKAKPTILFTVPRVWESFYDKIKDTIQKSHWIKKYFLKLLVWNSVQFSITY
DKAFDRIPRLITPKTFSLYILQIFNCIKLMIYLPLLPISKFVLSKILSVLGGRLRYAFAGAGALQAEVDRFMYAIGMPIL
EVYGMTENSGVSTIRHYNDFSVGNVGKPIQGVTIKLIDEFGKEIRKPGIKGVALHHGRHNMKGYYLEEEKTKAVLTDDRW
LNSGDLLVWTTQGNLKFAGRAKDTIVLSGGENVEPEPIEICLKQSDYIDQAVVVGQDKKTLSALIILNLEKVETYLKEQS
INMNLKNSIYQEVEIIQKLIRNEVKHFVSDKNGFKSFERISNVYILQNPFVVHDELTQTQKVKRNRVQEKYQKEIESMYR
K

Sequences:

>Translated_641_residues
MKVPSLSKLTIFHLLQEGRRLYGDLPVQSFKDHKKEYQNISYEEFVSNVTIISKALIHLNTNAGDRIGIIADVGHQWLQV
SMAITSIGCVDVPRGTDATQDDIGYILNHANCKIVFIENEKALNKFLPELRKLNLQIIILFGESKPDSMEIQCPIINFTD
LKIYSQEIEDKTYQEIGEEIQEEDLATIIYTSGTTGKPKGVMLTHGSILFEIQALVSEFRKTGVKVGEGDVTLGFLPPWH
SGERIFETICFYSGIKIAFTSVPELGKDLAKAKPTILFTVPRVWESFYDKIKDTIQKSHWIKKYFLKLLVWNSVQFSITY
DKAFDRIPRLITPKTFSLYILQIFNCIKLMIYLPLLPISKFVLSKILSVLGGRLRYAFAGAGALQAEVDRFMYAIGMPIL
EVYGMTENSGVSTIRHYNDFSVGNVGKPIQGVTIKLIDEFGKEIRKPGIKGVALHHGRHNMKGYYLEEEKTKAVLTDDRW
LNSGDLLVWTTQGNLKFAGRAKDTIVLSGGENVEPEPIEICLKQSDYIDQAVVVGQDKKTLSALIILNLEKVETYLKEQS
INMNLKNSIYQEVEIIQKLIRNEVKHFVSDKNGFKSFERISNVYILQNPFVVHDELTQTQKVKRNRVQEKYQKEIESMYR
K
>Mature_641_residues
MKVPSLSKLTIFHLLQEGRRLYGDLPVQSFKDHKKEYQNISYEEFVSNVTIISKALIHLNTNAGDRIGIIADVGHQWLQV
SMAITSIGCVDVPRGTDATQDDIGYILNHANCKIVFIENEKALNKFLPELRKLNLQIIILFGESKPDSMEIQCPIINFTD
LKIYSQEIEDKTYQEIGEEIQEEDLATIIYTSGTTGKPKGVMLTHGSILFEIQALVSEFRKTGVKVGEGDVTLGFLPPWH
SGERIFETICFYSGIKIAFTSVPELGKDLAKAKPTILFTVPRVWESFYDKIKDTIQKSHWIKKYFLKLLVWNSVQFSITY
DKAFDRIPRLITPKTFSLYILQIFNCIKLMIYLPLLPISKFVLSKILSVLGGRLRYAFAGAGALQAEVDRFMYAIGMPIL
EVYGMTENSGVSTIRHYNDFSVGNVGKPIQGVTIKLIDEFGKEIRKPGIKGVALHHGRHNMKGYYLEEEKTKAVLTDDRW
LNSGDLLVWTTQGNLKFAGRAKDTIVLSGGENVEPEPIEICLKQSDYIDQAVVVGQDKKTLSALIILNLEKVETYLKEQS
INMNLKNSIYQEVEIIQKLIRNEVKHFVSDKNGFKSFERISNVYILQNPFVVHDELTQTQKVKRNRVQEKYQKEIESMYR
K

Specific function: Unknown

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI42794756, Length=653, Percent_Identity=24.9617151607963, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI42794760, Length=653, Percent_Identity=24.9617151607963, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI42794758, Length=653, Percent_Identity=24.9617151607963, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI57165412, Length=659, Percent_Identity=27.4658573596358, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI83745141, Length=661, Percent_Identity=26.3237518910741, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI57165410, Length=660, Percent_Identity=26.6666666666667, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI40807491, Length=646, Percent_Identity=25.8513931888545, Blast_Score=183, Evalue=5e-46,
Organism=Homo sapiens, GI27477105, Length=669, Percent_Identity=25.2615844544096, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI4758332, Length=480, Percent_Identity=26.4583333333333, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI12669909, Length=480, Percent_Identity=26.4583333333333, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI42794754, Length=482, Percent_Identity=26.9709543568465, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI42794752, Length=482, Percent_Identity=26.9709543568465, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI145693145, Length=266, Percent_Identity=28.1954887218045, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788107, Length=186, Percent_Identity=28.494623655914, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17510401, Length=648, Percent_Identity=29.320987654321, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17541856, Length=651, Percent_Identity=28.8786482334869, Blast_Score=198, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17564090, Length=632, Percent_Identity=26.1075949367089, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI25147511, Length=678, Percent_Identity=23.7463126843658, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193204819, Length=684, Percent_Identity=25.2923976608187, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17553312, Length=638, Percent_Identity=23.8244514106583, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17556552, Length=619, Percent_Identity=23.7479806138934, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI133901848, Length=220, Percent_Identity=32.2727272727273, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560308, Length=174, Percent_Identity=34.4827586206897, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17558820, Length=228, Percent_Identity=25.4385964912281, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32563687, Length=204, Percent_Identity=27.4509803921569, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994690, Length=167, Percent_Identity=31.1377245508982, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994694, Length=167, Percent_Identity=31.1377245508982, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994703, Length=167, Percent_Identity=31.1377245508982, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324893, Length=645, Percent_Identity=24.6511627906977, Blast_Score=153, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6323903, Length=650, Percent_Identity=23.5384615384615, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6322182, Length=640, Percent_Identity=22.5, Blast_Score=138, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6320852, Length=473, Percent_Identity=24.3128964059197, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24666501, Length=643, Percent_Identity=26.905132192846, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24666497, Length=643, Percent_Identity=26.905132192846, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI281366413, Length=643, Percent_Identity=26.905132192846, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI17933690, Length=666, Percent_Identity=25.6756756756757, Blast_Score=186, Evalue=6e-47,
Organism=Drosophila melanogaster, GI62471689, Length=480, Percent_Identity=25.8333333333333, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI62471681, Length=480, Percent_Identity=25.8333333333333, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI62471687, Length=480, Percent_Identity=25.8333333333333, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24586634, Length=480, Percent_Identity=25.8333333333333, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI22026970, Length=480, Percent_Identity=25.8333333333333, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI62471679, Length=480, Percent_Identity=25.8333333333333, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471683, Length=480, Percent_Identity=25.8333333333333, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI62471685, Length=480, Percent_Identity=25.8333333333333, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24586636, Length=480, Percent_Identity=25.8333333333333, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI19921316, Length=700, Percent_Identity=22.7142857142857, Blast_Score=139, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24581924, Length=524, Percent_Identity=22.9007633587786, Blast_Score=84, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 73061; Mature: 73061

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVPSLSKLTIFHLLQEGRRLYGDLPVQSFKDHKKEYQNISYEEFVSNVTIISKALIHLN
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEE
TNAGDRIGIIADVGHQWLQVSMAITSIGCVDVPRGTDATQDDIGYILNHANCKIVFIENE
CCCCCEEEEEECCCHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHEECCCEEEEEEECH
KALNKFLPELRKLNLQIIILFGESKPDSMEIQCPIINFTDLKIYSQEIEDKTYQEIGEEI
HHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEEEEECEEEHHHHHHHHHHHHHHHHHHHH
QEEDLATIIYTSGTTGKPKGVMLTHGSILFEIQALVSEFRKTGVKVGEGDVTLGFLPPWH
HHCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCC
SGERIFETICFYSGIKIAFTSVPELGKDLAKAKPTILFTVPRVWESFYDKIKDTIQKSHW
CHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHH
IKKYFLKLLVWNSVQFSITYDKAFDRIPRLITPKTFSLYILQIFNCIKLMIYLPLLPISK
HHHHHHHHHHHCCEEEEEEEHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLSKILSVLGGRLRYAFAGAGALQAEVDRFMYAIGMPILEVYGMTENSGVSTIRHYNDF
HHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHCCCCC
SVGNVGKPIQGVTIKLIDEFGKEIRKPGIKGVALHHGRHNMKGYYLEEEKTKAVLTDDRW
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCCCEEEECCCC
LNSGDLLVWTTQGNLKFAGRAKDTIVLSGGENVEPEPIEICLKQSDYIDQAVVVGQDKKT
CCCCCEEEEEECCCEEECCCCCCEEEEECCCCCCCCHHHHEECCCCCCCCEEEECCCHHH
LSALIILNLEKVETYLKEQSINMNLKNSIYQEVEIIQKLIRNEVKHFVSDKNGFKSFERI
EEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SNVYILQNPFVVHDELTQTQKVKRNRVQEKYQKEIESMYRK
CCEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVPSLSKLTIFHLLQEGRRLYGDLPVQSFKDHKKEYQNISYEEFVSNVTIISKALIHLN
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEE
TNAGDRIGIIADVGHQWLQVSMAITSIGCVDVPRGTDATQDDIGYILNHANCKIVFIENE
CCCCCEEEEEECCCHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHEECCCEEEEEEECH
KALNKFLPELRKLNLQIIILFGESKPDSMEIQCPIINFTDLKIYSQEIEDKTYQEIGEEI
HHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEEEEECEEEHHHHHHHHHHHHHHHHHHHH
QEEDLATIIYTSGTTGKPKGVMLTHGSILFEIQALVSEFRKTGVKVGEGDVTLGFLPPWH
HHCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCC
SGERIFETICFYSGIKIAFTSVPELGKDLAKAKPTILFTVPRVWESFYDKIKDTIQKSHW
CHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHH
IKKYFLKLLVWNSVQFSITYDKAFDRIPRLITPKTFSLYILQIFNCIKLMIYLPLLPISK
HHHHHHHHHHHCCEEEEEEEHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLSKILSVLGGRLRYAFAGAGALQAEVDRFMYAIGMPILEVYGMTENSGVSTIRHYNDF
HHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHCCCCC
SVGNVGKPIQGVTIKLIDEFGKEIRKPGIKGVALHHGRHNMKGYYLEEEKTKAVLTDDRW
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCCCEEEECCCC
LNSGDLLVWTTQGNLKFAGRAKDTIVLSGGENVEPEPIEICLKQSDYIDQAVVVGQDKKT
CCCCCEEEEEECCCEEECCCCCCEEEEECCCCCCCCHHHHEECCCCCCCCEEEECCCHHH
LSALIILNLEKVETYLKEQSINMNLKNSIYQEVEIIQKLIRNEVKHFVSDKNGFKSFERI
EEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SNVYILQNPFVVHDELTQTQKVKRNRVQEKYQKEIESMYRK
CCEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]