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The map label for this gene is caiD [C]

Identifier: 183219535

GI number: 183219535

Start: 110100

End: 110885

Strand: Direct

Name: caiD [C]

Synonym: LEPBI_I0108

Alternate gene names: 183219535

Gene position: 110100-110885 (Clockwise)

Preceding gene: 183219534

Following gene: 183219536

Centisome position: 3.06

GC content: 32.7

Gene sequence:

>786_bases
ATGAAAACCTATCATTCATGGAAATTGGATATCGAAGATCGTATTGCAACTTTGACTCTTCACACAAATGATTTGAATGT
GATGGATATGCCATCTCTATTTGAATTAAAAGAAATCAGTAATGAATTGATTTCGAATGATGATGTTTGGGTGGTCATCT
TACAAGGAAATGGTAAACATTTCTCTTCTGGTGTTAATTTTGATATTTTAAAGAAAATCAATGAGATTTCAAAAGATGAA
TTTAAGAACAACATGCGCGAAATGCAAAGTTGTTTTACATCATTCGAAACAATATCGAAACCAACGATTGCAAAGATCCA
AGGCTTTTGTATGGGTGGTGGTTTTATGTTATCACAATGTTGTGATTTTAGAATTGCCAGCGAAAAAACTATTTTTTCAA
TTCCTCTCGTAAAACTAGGATTAACCGTATTGATGGGAACCAATCGGATCACACGGAATGCAGGGATTGGACCAACTAAT
GAACTAGTGATGTTAGGTGAAAAATTCAATCCTGAAAAAGCCTTACAATACAATTTGATCACAAAAATTGTATCCCCAGA
AAATTTTGATGATGCTACAAAACAATTTGCAAAGAAATTTTTACAACTTCCTCCCAAAACAATTTCCATCACAAAGGAAA
TCATTAGACGTGGAGATAAGGTATCACTGGAAGAAAGTTTGGAATTAGAAATTGAATTACAATCAAGTTTGTTAGGTTCA
TCAGATTTGTTAGAAGCAATGGAGAGTTTTGTAAGTCAAAGAAAACCAAAGTTTACCGGTAATTAA

Upstream 100 bases:

>100_bases
ATGACGAACTGACACAAACACAAAAAGTGAAACGAAACCGGGTGCAAGAAAAGTATCAGAAAGAAATAGAATCAATGTAT
CGGAAATAAAAGGATTTTAA

Downstream 100 bases:

>100_bases
TCATGAGCATTGAAGAACTTTGGCAAAATGGAAAAGAAACTGTAAATCGAATTAGACTTGTGCTTTTCTTTATCTTTTTT
GCCGCGTTATTCGGTACAAA

Product: putative enoyl-CoA hydratase/carnithine racemase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKTYHSWKLDIEDRIATLTLHTNDLNVMDMPSLFELKEISNELISNDDVWVVILQGNGKHFSSGVNFDILKKINEISKDE
FKNNMREMQSCFTSFETISKPTIAKIQGFCMGGGFMLSQCCDFRIASEKTIFSIPLVKLGLTVLMGTNRITRNAGIGPTN
ELVMLGEKFNPEKALQYNLITKIVSPENFDDATKQFAKKFLQLPPKTISITKEIIRRGDKVSLEESLELEIELQSSLLGS
SDLLEAMESFVSQRKPKFTGN

Sequences:

>Translated_261_residues
MKTYHSWKLDIEDRIATLTLHTNDLNVMDMPSLFELKEISNELISNDDVWVVILQGNGKHFSSGVNFDILKKINEISKDE
FKNNMREMQSCFTSFETISKPTIAKIQGFCMGGGFMLSQCCDFRIASEKTIFSIPLVKLGLTVLMGTNRITRNAGIGPTN
ELVMLGEKFNPEKALQYNLITKIVSPENFDDATKQFAKKFLQLPPKTISITKEIIRRGDKVSLEESLELEIELQSSLLGS
SDLLEAMESFVSQRKPKFTGN
>Mature_261_residues
MKTYHSWKLDIEDRIATLTLHTNDLNVMDMPSLFELKEISNELISNDDVWVVILQGNGKHFSSGVNFDILKKINEISKDE
FKNNMREMQSCFTSFETISKPTIAKIQGFCMGGGFMLSQCCDFRIASEKTIFSIPLVKLGLTVLMGTNRITRNAGIGPTN
ELVMLGEKFNPEKALQYNLITKIVSPENFDDATKQFAKKFLQLPPKTISITKEIIRRGDKVSLEESLELEIELQSSLLGS
SDLLEAMESFVSQRKPKFTGN

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=219, Percent_Identity=28.310502283105, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI70995211, Length=246, Percent_Identity=26.0162601626016, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI45643119, Length=216, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI260275230, Length=216, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI260274832, Length=216, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI31542718, Length=235, Percent_Identity=24.2553191489362, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI20127408, Length=156, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI221136756, Length=224, Percent_Identity=23.6607142857143, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI221136753, Length=224, Percent_Identity=23.6607142857143, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI116235487, Length=244, Percent_Identity=25.4098360655738, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI221307494, Length=224, Percent_Identity=23.6607142857143, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI213417737, Length=241, Percent_Identity=24.0663900414938, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI157694516, Length=241, Percent_Identity=24.0663900414938, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI157694520, Length=200, Percent_Identity=24.5, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI221142681, Length=254, Percent_Identity=26.7716535433071, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787659, Length=230, Percent_Identity=24.7826086956522, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082183, Length=184, Percent_Identity=28.2608695652174, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787660, Length=259, Percent_Identity=26.2548262548263, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788682, Length=206, Percent_Identity=24.7572815533981, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790281, Length=198, Percent_Identity=23.7373737373737, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17536985, Length=252, Percent_Identity=29.3650793650794, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17554946, Length=236, Percent_Identity=25.4237288135593, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=27.3809523809524, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17534483, Length=237, Percent_Identity=28.2700421940928, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540714, Length=198, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17558304, Length=165, Percent_Identity=27.8787878787879, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25144276, Length=190, Percent_Identity=27.8947368421053, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17508951, Length=190, Percent_Identity=27.8947368421053, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=190, Percent_Identity=27.8947368421053, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=165, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17535521, Length=226, Percent_Identity=22.1238938053097, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129971, Length=230, Percent_Identity=25.2173913043478, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653477, Length=230, Percent_Identity=25.2173913043478, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653139, Length=207, Percent_Identity=27.0531400966184, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920382, Length=161, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29473; Mature: 29473

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYHSWKLDIEDRIATLTLHTNDLNVMDMPSLFELKEISNELISNDDVWVVILQGNGKH
CCCCCCEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCC
FSSGVNFDILKKINEISKDEFKNNMREMQSCFTSFETISKPTIAKIQGFCMGGGFMLSQC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCEEECCHHHHHHH
CDFRIASEKTIFSIPLVKLGLTVLMGTNRITRNAGIGPTNELVMLGEKFNPEKALQYNLI
HCCEECCCCEEEECHHHHHHHHHHCCCCCEECCCCCCCCCCEEEECCCCCHHHHHHHHHH
TKIVSPENFDDATKQFAKKFLQLPPKTISITKEIIRRGDKVSLEESLELEIELQSSLLGS
HHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHCCC
SDLLEAMESFVSQRKPKFTGN
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKTYHSWKLDIEDRIATLTLHTNDLNVMDMPSLFELKEISNELISNDDVWVVILQGNGKH
CCCCCCEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCC
FSSGVNFDILKKINEISKDEFKNNMREMQSCFTSFETISKPTIAKIQGFCMGGGFMLSQC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCEEECCHHHHHHH
CDFRIASEKTIFSIPLVKLGLTVLMGTNRITRNAGIGPTNELVMLGEKFNPEKALQYNLI
HCCEECCCCEEEECHHHHHHHHHHCCCCCEECCCCCCCCCCEEEECCCCCHHHHHHHHHH
TKIVSPENFDDATKQFAKKFLQLPPKTISITKEIIRRGDKVSLEESLELEIELQSSLLGS
HHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHCCC
SDLLEAMESFVSQRKPKFTGN
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA