BacMap

Definition	Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence.
Accession	NC_010602
Length	3,599,677

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The map label for this gene is yusZ [H]

Identifier: 183219533

GI number: 183219533

Start: 107324

End: 108154

Strand: Direct

Name: yusZ [H]

Synonym: LEPBI_I0106

Alternate gene names: 183219533

Gene position: 107324-108154 (Clockwise)

Preceding gene: 183219532

Following gene: 183219534

Centisome position: 2.98

GC content: 34.66

Gene sequence:

>831_bases
ATGAGTAAGGTAATTGTAATTAGCGGAATTGCCCAAGGTATGGGTCGGGAAGTGTCATTGATGTTGGCATCACAAGGATA
TACTATTTGTGGATTTGATATTGAGAAAAAATATTTAGATAGTTTAGCAGATGAGTTAAATCAATTGAAGGCTAAGTTTC
ATCTCGAAACTTTAAGTGTTACTGATTCTGACAAAATTTTAAAATTTAAAGACACAGTATTAAAAAAGTTTGGATCAGTG
GATACAGTTGTTTCTAATGTTGGGATTGGTTTTTTTGGCCCGTTTGAAGAAGTCAATTTAGTAAAAGCATTACAGTGTTT
CGATATCAATGTTATTGGATGTGCAAGACTTTTACAGGCATTCATCCCTTCGATGCGTGAGAGAAAAAGTGGAAAGATAG
TTGTGATGTCATCACTTGTCGGCCAAGTTCCATTTCCTTTCGAATCAATTTATTCGGCGACTAAGTTTGCCATCGAAGGT
ATGGTTTCATCATTTCGATATGAAGTGAAACCATTTGGAATTCAAGTCGCGATGATCCAACCGGCACAGGTATCCACAAA
TTTTGCTGCCAAAGCGCAACAGTTACCTGATAAAAATTCACCTTACTATGATCGATGTGTTCGATTTATTAACCGTGATA
ATGAATTAATTAAAAAGGCAACGAATCCAAAACAAGCTGCAGAAAAAATCGTGAAAGTGATACAGTCAAAGAATCCAAAC
TTATTCAATCAGGTAGATTTCATGAGTAGTTTCTTTTTGGGTTTGAATCGTTTTTTGCCTCAAAAATTAAAAGATAAAAT
TCTACTCGATCACATGAATATCAATGTATAG

Upstream 100 bases:

>100_bases
TATATGGATAATGAGAAACTAAAATCAACTGGTTACAAGTTACTGTATCCAAATTTTGTTTCTTCAATGGAATCAATGAA
ATTAATTTAAAGAGGATAAA

Downstream 100 bases:

>100_bases
GAAGAAGAATGAAAGTTCCGAGTCTCAGTAAATTGACAATATTTCACTTGCTCCAAGAAGGAAGACGTCTTTACGGCGAT
CTTCCTGTGCAAAGTTTTAA

Product: putative short chain dehydrogenase

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSKVIVISGIAQGMGREVSLMLASQGYTICGFDIEKKYLDSLADELNQLKAKFHLETLSVTDSDKILKFKDTVLKKFGSV
DTVVSNVGIGFFGPFEEVNLVKALQCFDINVIGCARLLQAFIPSMRERKSGKIVVMSSLVGQVPFPFESIYSATKFAIEG
MVSSFRYEVKPFGIQVAMIQPAQVSTNFAAKAQQLPDKNSPYYDRCVRFINRDNELIKKATNPKQAAEKIVKVIQSKNPN
LFNQVDFMSSFFLGLNRFLPQKLKDKILLDHMNINV

Sequences:

>Translated_276_residues
MSKVIVISGIAQGMGREVSLMLASQGYTICGFDIEKKYLDSLADELNQLKAKFHLETLSVTDSDKILKFKDTVLKKFGSV
DTVVSNVGIGFFGPFEEVNLVKALQCFDINVIGCARLLQAFIPSMRERKSGKIVVMSSLVGQVPFPFESIYSATKFAIEG
MVSSFRYEVKPFGIQVAMIQPAQVSTNFAAKAQQLPDKNSPYYDRCVRFINRDNELIKKATNPKQAAEKIVKVIQSKNPN
LFNQVDFMSSFFLGLNRFLPQKLKDKILLDHMNINV
>Mature_275_residues
SKVIVISGIAQGMGREVSLMLASQGYTICGFDIEKKYLDSLADELNQLKAKFHLETLSVTDSDKILKFKDTVLKKFGSVD
TVVSNVGIGFFGPFEEVNLVKALQCFDINVIGCARLLQAFIPSMRERKSGKIVVMSSLVGQVPFPFESIYSATKFAIEGM
VSSFRYEVKPFGIQVAMIQPAQVSTNFAAKAQQLPDKNSPYYDRCVRFINRDNELIKKATNPKQAAEKIVKVIQSKNPNL
FNQVDFMSSFFLGLNRFLPQKLKDKILLDHMNINV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI223718074, Length=269, Percent_Identity=28.996282527881, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI7657478, Length=262, Percent_Identity=30.1526717557252, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=31.4720812182741, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI210032110, Length=191, Percent_Identity=25.6544502617801, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4503817, Length=270, Percent_Identity=27.4074074074074, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI157739938, Length=248, Percent_Identity=24.1935483870968, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI44680136, Length=300, Percent_Identity=23.3333333333333, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI44680133, Length=300, Percent_Identity=23.3333333333333, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI17738292, Length=300, Percent_Identity=23.3333333333333, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI142976729, Length=189, Percent_Identity=25.3968253968254, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI7706318, Length=224, Percent_Identity=26.7857142857143, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI32483357, Length=195, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI7705855, Length=205, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI19743808, Length=286, Percent_Identity=23.4265734265734, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI119392083, Length=192, Percent_Identity=26.5625, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI32455239, Length=197, Percent_Identity=26.9035532994924, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5031765, Length=197, Percent_Identity=26.9035532994924, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI150247226, Length=210, Percent_Identity=25.7142857142857, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786701, Length=274, Percent_Identity=25.5474452554745, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI87082100, Length=201, Percent_Identity=30.3482587064677, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787335, Length=187, Percent_Identity=25.1336898395722, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786812, Length=187, Percent_Identity=22.9946524064171, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787526, Length=195, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=190, Percent_Identity=22.6315789473684, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787905, Length=141, Percent_Identity=24.822695035461, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=177, Percent_Identity=27.1186440677966, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=188, Percent_Identity=26.5957446808511, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=205, Percent_Identity=24.8780487804878, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193210355, Length=193, Percent_Identity=26.4248704663212, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=268, Percent_Identity=22.3880597014925, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17570069, Length=268, Percent_Identity=22.3880597014925, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17557780, Length=192, Percent_Identity=25.5208333333333, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=217, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=217, Percent_Identity=28.110599078341, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17559552, Length=209, Percent_Identity=27.7511961722488, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=195, Percent_Identity=26.1538461538462, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=183, Percent_Identity=25.6830601092896, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=29.7435897435897, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322067, Length=295, Percent_Identity=27.4576271186441, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=27.1276595744681, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640492, Length=258, Percent_Identity=27.906976744186, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281364892, Length=235, Percent_Identity=27.6595744680851, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21358495, Length=245, Percent_Identity=26.1224489795918, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24663911, Length=196, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648944, Length=194, Percent_Identity=27.319587628866, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355631, Length=288, Percent_Identity=26.0416666666667, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=28.0612244897959, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643142, Length=201, Percent_Identity=28.8557213930348, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007238, Length=182, Percent_Identity=28.021978021978, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355319, Length=188, Percent_Identity=26.5957446808511, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581726, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=26.2032085561497, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356301, Length=191, Percent_Identity=22.5130890052356, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571526, Length=207, Percent_Identity=25.6038647342995, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24580925, Length=199, Percent_Identity=25.1256281407035, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21357041, Length=189, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24640442, Length=198, Percent_Identity=26.2626262626263, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24641232, Length=198, Percent_Identity=24.2424242424242, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30916; Mature: 30784

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVIVISGIAQGMGREVSLMLASQGYTICGFDIEKKYLDSLADELNQLKAKFHLETLSV
CCCEEEEECHHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEEE
TDSDKILKFKDTVLKKFGSVDTVVSNVGIGFFGPFEEVNLVKALQCFDINVIGCARLLQA
CCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
FIPSMRERKSGKIVVMSSLVGQVPFPFESIYSATKFAIEGMVSSFRYEVKPFGIQVAMIQ
HHHHHHHCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEC
PAQVSTNFAAKAQQLPDKNSPYYDRCVRFINRDNELIKKATNPKQAAEKIVKVIQSKNPN
CCHHCCHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCC
LFNQVDFMSSFFLGLNRFLPQKLKDKILLDHMNINV
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKVIVISGIAQGMGREVSLMLASQGYTICGFDIEKKYLDSLADELNQLKAKFHLETLSV
CCEEEEECHHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEEE
TDSDKILKFKDTVLKKFGSVDTVVSNVGIGFFGPFEEVNLVKALQCFDINVIGCARLLQA
CCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
FIPSMRERKSGKIVVMSSLVGQVPFPFESIYSATKFAIEGMVSSFRYEVKPFGIQVAMIQ
HHHHHHHCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEC
PAQVSTNFAAKAQQLPDKNSPYYDRCVRFINRDNELIKKATNPKQAAEKIVKVIQSKNPN
CCHHCCHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCC
LFNQVDFMSSFFLGLNRFLPQKLKDKILLDHMNINV
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]