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The map label for this gene is tlyA [H]

Identifier: 183219509

GI number: 183219509

Start: 82068

End: 82841

Strand: Reverse

Name: tlyA [H]

Synonym: LEPBI_I0082

Alternate gene names: 183219509

Gene position: 82841-82068 (Counterclockwise)

Preceding gene: 183219510

Following gene: 183219507

Centisome position: 2.3

GC content: 38.24

Gene sequence:

>774_bases
TTGCTGAAAGAAAAAATTAGACTCGATGATTATCTCGTTCGCGAAGGTTATGCGAAAGATTTAAAATTAGCACAATCATT
AATCCTATCAGGATCGGTACTCGTCAATGATACTATCGTCTCCAAAGTAGGAACACTTATCTCAAACAAAGATAAAGTGA
GAACCAAAGAAAAAATCAAAACATATGTTTCGCGAGGTGCTTACAAACTCCTTGGTGCCTTTGACCGTTGGAAAACAATC
CAAGTTGAAGGTAAAACTTGTATTGATTTGGGTGCTTCGACTGGTGGGTTCTGCCAAGTATTATTGGAAAAAGGAGCCAT
TCGTGTCATCGCCGTGGATGTCGGTTACGGACAATTGGCTCAAAAGATTGCCAATGATCCAAAAGTTTTTGTATTGGATC
GAACTCACCTACGAGAGTTACCAAAGTTGCCACTCGGAGCCCTGACAAAAGAAACTTGGATCACGATGGATTTGAGTTTT
ATTTCGTTAGTTCCTGTCTTTAGCCATCTATTACCATTGTTTCAAAAATACCCAGACATCCATTGGCAAGGGATATCACT
TTTCAAACCTCAATTTGAGGTCCATCCTTCAAAGTTAGAAAAAGGGATTTTAATTGATTCGCATAATATCGGTAAAACGA
TTAAAAATGTTTGGTTAAAGATCAAAAAAAATGATCCAAAACTTGAATTCCTTGGGTTAGGTGAATCTCCTATCCAAGGT
GCGGATGGCAATCGTGAGTTTTTGATTCGATGGGAAAGAAGGTCAGAAAGTTAA

Upstream 100 bases:

>100_bases
TCAAAATTACTTCGCGACCAAACGCTTGGTAAGGCCATTTCTTTGGCAGCGGAACTTCCCTCTTTACACAATGAATTCTT
TTTAGGATTGCCTAAGTACA

Downstream 100 bases:

>100_bases
ACCATAAATCCAGTGACCGCTTCTTTCAATTGGTCAGTTGAAAATGGTTTCATAAGATAGGCATAAGATGAATTTTGATT
GATTCGTTGTTTTGACGTTT

Product: putative ribosomal RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLKEKIRLDDYLVREGYAKDLKLAQSLILSGSVLVNDTIVSKVGTLISNKDKVRTKEKIKTYVSRGAYKLLGAFDRWKTI
QVEGKTCIDLGASTGGFCQVLLEKGAIRVIAVDVGYGQLAQKIANDPKVFVLDRTHLRELPKLPLGALTKETWITMDLSF
ISLVPVFSHLLPLFQKYPDIHWQGISLFKPQFEVHPSKLEKGILIDSHNIGKTIKNVWLKIKKNDPKLEFLGLGESPIQG
ADGNREFLIRWERRSES

Sequences:

>Translated_257_residues
MLKEKIRLDDYLVREGYAKDLKLAQSLILSGSVLVNDTIVSKVGTLISNKDKVRTKEKIKTYVSRGAYKLLGAFDRWKTI
QVEGKTCIDLGASTGGFCQVLLEKGAIRVIAVDVGYGQLAQKIANDPKVFVLDRTHLRELPKLPLGALTKETWITMDLSF
ISLVPVFSHLLPLFQKYPDIHWQGISLFKPQFEVHPSKLEKGILIDSHNIGKTIKNVWLKIKKNDPKLEFLGLGESPIQG
ADGNREFLIRWERRSES
>Mature_257_residues
MLKEKIRLDDYLVREGYAKDLKLAQSLILSGSVLVNDTIVSKVGTLISNKDKVRTKEKIKTYVSRGAYKLLGAFDRWKTI
QVEGKTCIDLGASTGGFCQVLLEKGAIRVIAVDVGYGQLAQKIANDPKVFVLDRTHLRELPKLPLGALTKETWITMDLSF
ISLVPVFSHLLPLFQKYPDIHWQGISLFKPQFEVHPSKLEKGILIDSHNIGKTIKNVWLKIKKNDPKLEFLGLGESPIQG
ADGNREFLIRWERRSES

Specific function: Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined [H]

COG id: COG1189

COG function: function code J; Predicted rRNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004538
- InterPro:   IPR002877
- InterPro:   IPR002942 [H]

Pfam domain/function: PF01728 FtsJ; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 29012; Mature: 29012

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKEKIRLDDYLVREGYAKDLKLAQSLILSGSVLVNDTIVSKVGTLISNKDKVRTKEKIK
CCCCHHCHHHHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHH
TYVSRGAYKLLGAFDRWKTIQVEGKTCIDLGASTGGFCQVLLEKGAIRVIAVDVGYGQLA
HHHHCCHHHHHHHHCCCEEEEECCCEEEEECCCCCHHHHHHHHCCCEEEEEEECCHHHHH
QKIANDPKVFVLDRTHLRELPKLPLGALTKETWITMDLSFISLVPVFSHLLPLFQKYPDI
HHHCCCCEEEEEEHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCC
HWQGISLFKPQFEVHPSKLEKGILIDSHNIGKTIKNVWLKIKKNDPKLEFLGLGESPIQG
CCCCCEEECCCCCCCHHHHCCCEEEECCCHHHHHHHHEEEEECCCCCEEEEECCCCCCCC
ADGNREFLIRWERRSES
CCCCCEEEEEEECCCCC
>Mature Secondary Structure
MLKEKIRLDDYLVREGYAKDLKLAQSLILSGSVLVNDTIVSKVGTLISNKDKVRTKEKIK
CCCCHHCHHHHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHH
TYVSRGAYKLLGAFDRWKTIQVEGKTCIDLGASTGGFCQVLLEKGAIRVIAVDVGYGQLA
HHHHCCHHHHHHHHCCCEEEEECCCEEEEECCCCCHHHHHHHHCCCEEEEEEECCHHHHH
QKIANDPKVFVLDRTHLRELPKLPLGALTKETWITMDLSFISLVPVFSHLLPLFQKYPDI
HHHCCCCEEEEEEHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCC
HWQGISLFKPQFEVHPSKLEKGILIDSHNIGKTIKNVWLKIKKNDPKLEFLGLGESPIQG
CCCCCEEECCCCCCCHHHHCCCEEEECCCHHHHHHHHEEEEECCCCCEEEEECCCCCCCC
ADGNREFLIRWERRSES
CCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730486 [H]