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The map label for this gene is dapB

Identifier: 182677133

GI number: 182677133

Start: 155522

End: 156337

Strand: Direct

Name: dapB

Synonym: Bind_0132

Alternate gene names: 182677133

Gene position: 155522-156337 (Clockwise)

Preceding gene: 182677132

Following gene: 182677134

Centisome position: 3.73

GC content: 64.83

Gene sequence:

>816_bases
ATGAGCGAGTTGAAGCTCGTTGTCGCGGGCGCCGCCGGGCGCATGGGCCGCGTGCTCATCCAGACGGCCATCGAGACGTC
GGGCGTCACGGTCAGCGCGGCGCTGGCGCGTCCCGGCTCGCTGGCACTCGGGCAAGATGCCGGCCTTCTCGCTGGTTGTG
GCGAGATCAATGTGCCGATCACGGAGGATGCGCTGGCGGCGATCGTCGACGCCGATGGCATTCTCGATTTCACATCGCCT
GATCTCAGTGTCGAATTGGCGGCGCTCGCGGCGCAGGCGCGGATCGTCCATATCATCGGTACCACGGGTTTCAGCGTCGC
GCATCTGACCAAGATCGAAGCCGCGGCGCGGCACGCCGTCATTGTCCGCTCAGGCAATATGAGCCTCGGTGTCAATCTTC
TGGCGGCGCTGGTGAAGAAGACGGCGGCCGTGCTCGGACCGGTCTATGATATCGAAATCGCTGAAATGCATCATCGCATG
AAGGTTGATGCGCCCTCGGGGACGGCGCTTTTGCTTGGCGAGGCGGCGGCCCAGGGGCGTGGCATTTCCTTGAGCGAGCA
TGAACAGCGGGGGCGCGATGGCCATACCGGCCCGCGCAAGGACGGGGATATTGGTTTCGTGTCGTTGCGCGGCGGCACGG
TCGTCGGCGATCATACGGTGATCTTCGCGGGGCCGGGAGAGCGGATCGAATTGGCGCACCGGGCGGAAGACCGCCGCATT
TTCGGTCGCGGTGCCGTCCAGGCCGCCCTCTGGGGCAAGGGCCGCAAACCAGGCCTTTATTCCATGCTCGACGTTTTGGG
GCTTGGTGGGGAATAA

Upstream 100 bases:

>100_bases
TCAGATCGTCGCGGAAATCGAGGCGACGCTTGCATCCATGGCTCCCCCGCCGGATAAGCCATGACGAGAGTCTGGCTGAA
GTAGATCGGAGAGTTCTCCC

Downstream 100 bases:

>100_bases
TGGAACCGCCGATTCATCGGCTTGCTTTATTCACGAGACCCCGCCTTGAGCAAAACGCCTGAACGCCTCGTGACCTCCGA
GGTCCGCGACGAAGATATGA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSELKLVVAGAAGRMGRVLIQTAIETSGVTVSAALARPGSLALGQDAGLLAGCGEINVPITEDALAAIVDADGILDFTSP
DLSVELAALAAQARIVHIIGTTGFSVAHLTKIEAAARHAVIVRSGNMSLGVNLLAALVKKTAAVLGPVYDIEIAEMHHRM
KVDAPSGTALLLGEAAAQGRGISLSEHEQRGRDGHTGPRKDGDIGFVSLRGGTVVGDHTVIFAGPGERIELAHRAEDRRI
FGRGAVQAALWGKGRKPGLYSMLDVLGLGGE

Sequences:

>Translated_271_residues
MSELKLVVAGAAGRMGRVLIQTAIETSGVTVSAALARPGSLALGQDAGLLAGCGEINVPITEDALAAIVDADGILDFTSP
DLSVELAALAAQARIVHIIGTTGFSVAHLTKIEAAARHAVIVRSGNMSLGVNLLAALVKKTAAVLGPVYDIEIAEMHHRM
KVDAPSGTALLLGEAAAQGRGISLSEHEQRGRDGHTGPRKDGDIGFVSLRGGTVVGDHTVIFAGPGERIELAHRAEDRRI
FGRGAVQAALWGKGRKPGLYSMLDVLGLGGE
>Mature_270_residues
SELKLVVAGAAGRMGRVLIQTAIETSGVTVSAALARPGSLALGQDAGLLAGCGEINVPITEDALAAIVDADGILDFTSPD
LSVELAALAAQARIVHIIGTTGFSVAHLTKIEAAARHAVIVRSGNMSLGVNLLAALVKKTAAVLGPVYDIEIAEMHHRMK
VDAPSGTALLLGEAAAQGRGISLSEHEQRGRDGHTGPRKDGDIGFVSLRGGTVVGDHTVIFAGPGERIELAHRAEDRRIF
GRGAVQAALWGKGRKPGLYSMLDVLGLGGE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=267, Percent_Identity=46.4419475655431, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_BEII9 (B2IBR8)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001831279.1
- GeneID:   6201446
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_0132
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27863; Mature: 27732

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELKLVVAGAAGRMGRVLIQTAIETSGVTVSAALARPGSLALGQDAGLLAGCGEINVPI
CCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCEEECCCCCCCCC
TEDALAAIVDADGILDFTSPDLSVELAALAAQARIVHIIGTTGFSVAHLTKIEAAARHAV
CHHHHHHEECCCCEEEECCCCCEEEHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHCEEE
IVRSGNMSLGVNLLAALVKKTAAVLGPVYDIEIAEMHHRMKVDAPSGTALLLGEAAAQGR
EEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHEEEECCCCCEEEEECHHCCCC
GISLSEHEQRGRDGHTGPRKDGDIGFVSLRGGTVVGDHTVIFAGPGERIELAHRAEDRRI
CCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCEEECCCEEEEECCCCEEEEECCCCCCEE
FGRGAVQAALWGKGRKPGLYSMLDVLGLGGE
ECCCCEEEEECCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SELKLVVAGAAGRMGRVLIQTAIETSGVTVSAALARPGSLALGQDAGLLAGCGEINVPI
CCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCEEECCCCCCCCC
TEDALAAIVDADGILDFTSPDLSVELAALAAQARIVHIIGTTGFSVAHLTKIEAAARHAV
CHHHHHHEECCCCEEEECCCCCEEEHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHCEEE
IVRSGNMSLGVNLLAALVKKTAAVLGPVYDIEIAEMHHRMKVDAPSGTALLLGEAAAQGR
EEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHEEEECCCCCEEEEECHHCCCC
GISLSEHEQRGRDGHTGPRKDGDIGFVSLRGGTVVGDHTVIFAGPGERIELAHRAEDRRI
CCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCEEECCCEEEEECCCCEEEEECCCCCCEE
FGRGAVQAALWGKGRKPGLYSMLDVLGLGGE
ECCCCEEEEECCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA