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The map label for this gene is sucD [H]

Identifier: 182682550

GI number: 182682550

Start: 2282117

End: 2282989

Strand: Direct

Name: sucD [H]

Synonym: XfasM23_2038

Alternate gene names: 182682550

Gene position: 2282117-2282989 (Clockwise)

Preceding gene: 182682549

Following gene: 182682551

Centisome position: 90.0

GC content: 51.09

Gene sequence:

>873_bases
ATGTCTGTACTGGTTAATAAAAATACGAAGGTGATCGTACAAGGCTTCACCGGTCAACAAGGGACCTTCCATGCCACTCA
AATGGTGGAATACGGCACCCAAGTCGTCGGCGGTGTTACCCCCGGCAAGGGAGGAAATACTCATATTGATCTACCGGTAT
TCAATACTGTGCGTGAAGCAGTCCAGAACACAGGTGCCGACGCCTCAGTGATCTACGTACCACCACCGTTTGCAGCGGAT
GCAATCTTGGAAGCAGCTGCAGCAGGCATCAAAGTCATCGTAGCGATTACTGAAGGTATCCCCGTGCTGGATATGCTACG
CGTTAAAAATGTACTTAAAGCATCACCTGAAATCACCTTGATAGGACCAAACTGCCCAGGCGTCATTACACCAGGAGAGT
GCAAGATAGGCATTATGCCTGGCCATATCCACAAGCCAGGTCATATCGGTATTGTGTCCCGCTCCGGTACCTTGACTTAC
GAAGCAGTGAAGCAAACCACTGACGTCGGCCTCGGTCAATCAACCTGCATCGGTATCGGTGGGGATCCAATCAACGGGCT
GAACTTCGTTGATGCGCTAAAACTGTTCAATAACGACCCGCAGACCAAAGGCATCATCATGGTAGGCGAGATCGGCGGGG
ATGCTGAGGAAGCCGGGGCTGAATATATTAAACACCATGTGAAAAAACCGGTGGTTGGCTTTATCGCTGGTGCATCCGCA
CCGAAAGGCAAGCGTATGGGTCATGCTGGCGCCATCGCCTCAGGAGGCTCAGGAACAGCTGAAGGCAAGTTTGCTGCAAT
GGAAAAAGCAGGCATCAAGACAGTACGTTCACCGGGAGATTTAGGTGCAGCGATTGCTTTGCTCGTAAGATAG

Upstream 100 bases:

>100_bases
GGCCTCGCCATCATCCCGGCTGACGACATCAACGACGGCGCCAAAAAAGCCGTGGCCGCTGTCACCGTCTGAACTCACCG
AGACCCTTTAGGAATTCAAC

Downstream 100 bases:

>100_bases
AACCCTCAAGTGAGGGCATATGATGCGTTGTTAAGAAACTATTTTTCAAAGTTTCTCCACACATTCCAGACGTATCGCTG
AAAAACGCCTCGACAAATAA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSVLVNKNTKVIVQGFTGQQGTFHATQMVEYGTQVVGGVTPGKGGNTHIDLPVFNTVREAVQNTGADASVIYVPPPFAAD
AILEAAAAGIKVIVAITEGIPVLDMLRVKNVLKASPEITLIGPNCPGVITPGECKIGIMPGHIHKPGHIGIVSRSGTLTY
EAVKQTTDVGLGQSTCIGIGGDPINGLNFVDALKLFNNDPQTKGIIMVGEIGGDAEEAGAEYIKHHVKKPVVGFIAGASA
PKGKRMGHAGAIASGGSGTAEGKFAAMEKAGIKTVRSPGDLGAAIALLVR

Sequences:

>Translated_290_residues
MSVLVNKNTKVIVQGFTGQQGTFHATQMVEYGTQVVGGVTPGKGGNTHIDLPVFNTVREAVQNTGADASVIYVPPPFAAD
AILEAAAAGIKVIVAITEGIPVLDMLRVKNVLKASPEITLIGPNCPGVITPGECKIGIMPGHIHKPGHIGIVSRSGTLTY
EAVKQTTDVGLGQSTCIGIGGDPINGLNFVDALKLFNNDPQTKGIIMVGEIGGDAEEAGAEYIKHHVKKPVVGFIAGASA
PKGKRMGHAGAIASGGSGTAEGKFAAMEKAGIKTVRSPGDLGAAIALLVR
>Mature_289_residues
SVLVNKNTKVIVQGFTGQQGTFHATQMVEYGTQVVGGVTPGKGGNTHIDLPVFNTVREAVQNTGADASVIYVPPPFAADA
ILEAAAAGIKVIVAITEGIPVLDMLRVKNVLKASPEITLIGPNCPGVITPGECKIGIMPGHIHKPGHIGIVSRSGTLTYE
AVKQTTDVGLGQSTCIGIGGDPINGLNFVDALKLFNNDPQTKGIIMVGEIGGDAEEAGAEYIKHHVKKPVVGFIAGASAP
KGKRMGHAGAIASGGSGTAEGKFAAMEKAGIKTVRSPGDLGAAIALLVR

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=65.5052264808362, Blast_Score=327, Evalue=6e-90,
Organism=Homo sapiens, GI38569423, Length=313, Percent_Identity=31.629392971246, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI38569421, Length=313, Percent_Identity=31.629392971246, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI1786949, Length=290, Percent_Identity=71.0344827586207, Blast_Score=421, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=63.1399317406143, Blast_Score=337, Evalue=6e-93,
Organism=Caenorhabditis elegans, GI17550194, Length=286, Percent_Identity=62.2377622377622, Blast_Score=333, Evalue=6e-92,
Organism=Caenorhabditis elegans, GI17551266, Length=316, Percent_Identity=30.6962025316456, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17557344, Length=312, Percent_Identity=29.8076923076923, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=53.4246575342466, Blast_Score=288, Evalue=7e-79,
Organism=Drosophila melanogaster, GI21356559, Length=285, Percent_Identity=57.8947368421053, Blast_Score=342, Evalue=1e-94,
Organism=Drosophila melanogaster, GI28574296, Length=282, Percent_Identity=60.9929078014184, Blast_Score=313, Evalue=8e-86,
Organism=Drosophila melanogaster, GI281363477, Length=310, Percent_Identity=28.7096774193548, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363475, Length=310, Percent_Identity=28.7096774193548, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281363473, Length=310, Percent_Identity=28.7096774193548, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29612; Mature: 29480

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVNKNTKVIVQGFTGQQGTFHATQMVEYGTQVVGGVTPGKGGNTHIDLPVFNTVREA
CEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHH
VQNTGADASVIYVPPPFAADAILEAAAAGIKVIVAITEGIPVLDMLRVKNVLKASPEITL
HHHCCCCCEEEEECCCCHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEE
IGPNCPGVITPGECKIGIMPGHIHKPGHIGIVSRSGTLTYEAVKQTTDVGLGQSTCIGIG
ECCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECC
GDPINGLNFVDALKLFNNDPQTKGIIMVGEIGGDAEEAGAEYIKHHVKKPVVGFIAGASA
CCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCC
PKGKRMGHAGAIASGGSGTAEGKFAAMEKAGIKTVRSPGDLGAAIALLVR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHEEEC
>Mature Secondary Structure 
SVLVNKNTKVIVQGFTGQQGTFHATQMVEYGTQVVGGVTPGKGGNTHIDLPVFNTVREA
EEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHH
VQNTGADASVIYVPPPFAADAILEAAAAGIKVIVAITEGIPVLDMLRVKNVLKASPEITL
HHHCCCCCEEEEECCCCHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEE
IGPNCPGVITPGECKIGIMPGHIHKPGHIGIVSRSGTLTYEAVKQTTDVGLGQSTCIGIG
ECCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECC
GDPINGLNFVDALKLFNNDPQTKGIIMVGEIGGDAEEAGAEYIKHHVKKPVVGFIAGASA
CCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCC
PKGKRMGHAGAIASGGSGTAEGKFAAMEKAGIKTVRSPGDLGAAIALLVR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]