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The map label for this gene is sucC

Identifier: 182682549

GI number: 182682549

Start: 2280925

End: 2282088

Strand: Direct

Name: sucC

Synonym: XfasM23_2037

Alternate gene names: 182682549

Gene position: 2280925-2282088 (Clockwise)

Preceding gene: 182682546

Following gene: 182682550

Centisome position: 89.95

GC content: 51.8

Gene sequence:

>1164_bases
ATGAATTTCCACGAATACCAGGCAAAACAACTATTTGCCGAATACGGCATCCCTGTTCCGGCCGGACGCATCGCGTCTTC
AGCCGATGAAGCGGTCACAGCCGCCAAATCCTTGGGCAACGGCCCCTGGATGGTAAAAGCTCAGATTCATGCGGGCGGTC
GCGGTAAGGCCGGCGGCGTGAAATTCTGCAAGACAACCGACGAAGTGAAACAGGCCGCAGCAACAATGCTCGGTACCAAG
ATGGCTACTTACCAGTCAGCAGGTGTCGCTCTGCCGGTGAATCTGGTCCTGGTCACCGAAGCCGGTGAAATCACTAAAGA
ACTCTATCTGTCAGTGTTAGTGGATCGCGGCACGCGTTCAATCACCTACATCGCCTCATCCGAGGGTGGCGTGGACATTG
AGCACGTTGCAGCTGAAACCCCTGAAAAAATCCAAACGCTCAACGTCGACTTTGTCGAAGGCCTACAGCCATACCAAGGA
CGCGATATTGGATTTCACCTCGGCTTAGAAGCAAAACAGGTTAATCAGCTGTCCAAAATCATGATTAGCCTCTATCAATT
GTTCAACGACAAAGATTTGTCCTTGATCGAATTAAATCCATTAGCAATCCTGAGCAATGGGGATTTGTACGCACTGGATG
GAAAAATTAATTCCGACGACAACGCCACATTCCGACATAAAGAATTGGCCGCAATGCGCGATAAAACTCAGGAAGACGAA
ACCGAGGTTCTAGCTTCAGAAAACGATCTGAACTACGTCACCATGGATGGCAACATCGGCTGCATGGTCAATGGAGCCGG
ACTTGCCATGGCCACGATGGATGTGATCAAACTCAATGGCGGCGAACCGGCAAACTTCCTTGATGTCGGTGGCGGCGCTA
CCAAAGAGCGCGTGACGACCGCATTCAAACTGATCCTTTCCTCAAACAAGGTCAAAGCCATCTTTGTCAATATCTTCGGT
GGCATTGTCCGCTGCGACATGATTGCCGAAGGCATCATCGCTGCAGTGAAGGAGGTGGGTGTCAAAGTGCCTGTTATCGT
ACGCTTGGAAGGCACCAATGTAGACGCTGGCAAACAACTGCTAGCTACATCCGGCCTCGCCATCATCCCGGCTGACGACA
TCAACGACGGCGCCAAAAAAGCCGTGGCCGCTGTCACCGTCTGA

Upstream 100 bases:

>100_bases
GTGAGCGACAATGAGCAGCCCGCTTGCACCCATGACGGTGTCTGCCATTGGCAAACATCCAGCCTTGCATAGCGATCGTT
TCCATTCTCGACGGTGACGC

Downstream 100 bases:

>100_bases
ACTCACCGAGACCCTTTAGGAATTCAACATGTCTGTACTGGTTAATAAAAATACGAAGGTGATCGTACAAGGCTTCACCG
GTCAACAAGGGACCTTCCAT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNFHEYQAKQLFAEYGIPVPAGRIASSADEAVTAAKSLGNGPWMVKAQIHAGGRGKAGGVKFCKTTDEVKQAAATMLGTK
MATYQSAGVALPVNLVLVTEAGEITKELYLSVLVDRGTRSITYIASSEGGVDIEHVAAETPEKIQTLNVDFVEGLQPYQG
RDIGFHLGLEAKQVNQLSKIMISLYQLFNDKDLSLIELNPLAILSNGDLYALDGKINSDDNATFRHKELAAMRDKTQEDE
TEVLASENDLNYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGATKERVTTAFKLILSSNKVKAIFVNIFG
GIVRCDMIAEGIIAAVKEVGVKVPVIVRLEGTNVDAGKQLLATSGLAIIPADDINDGAKKAVAAVTV

Sequences:

>Translated_387_residues
MNFHEYQAKQLFAEYGIPVPAGRIASSADEAVTAAKSLGNGPWMVKAQIHAGGRGKAGGVKFCKTTDEVKQAAATMLGTK
MATYQSAGVALPVNLVLVTEAGEITKELYLSVLVDRGTRSITYIASSEGGVDIEHVAAETPEKIQTLNVDFVEGLQPYQG
RDIGFHLGLEAKQVNQLSKIMISLYQLFNDKDLSLIELNPLAILSNGDLYALDGKINSDDNATFRHKELAAMRDKTQEDE
TEVLASENDLNYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGATKERVTTAFKLILSSNKVKAIFVNIFG
GIVRCDMIAEGIIAAVKEVGVKVPVIVRLEGTNVDAGKQLLATSGLAIIPADDINDGAKKAVAAVTV
>Mature_387_residues
MNFHEYQAKQLFAEYGIPVPAGRIASSADEAVTAAKSLGNGPWMVKAQIHAGGRGKAGGVKFCKTTDEVKQAAATMLGTK
MATYQSAGVALPVNLVLVTEAGEITKELYLSVLVDRGTRSITYIASSEGGVDIEHVAAETPEKIQTLNVDFVEGLQPYQG
RDIGFHLGLEAKQVNQLSKIMISLYQLFNDKDLSLIELNPLAILSNGDLYALDGKINSDDNATFRHKELAAMRDKTQEDE
TEVLASENDLNYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGATKERVTTAFKLILSSNKVKAIFVNIFG
GIVRCDMIAEGIIAAVKEVGVKVPVIVRLEGTNVDAGKQLLATSGLAIIPADDINDGAKKAVAAVTV

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=46.7866323907455, Blast_Score=352, Evalue=5e-97,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=45.1697127937337, Blast_Score=321, Evalue=9e-88,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=45.4038997214485, Blast_Score=303, Evalue=1e-82,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=58.4415584415584, Blast_Score=450, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=46.9072164948454, Blast_Score=349, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=42.6395939086294, Blast_Score=320, Evalue=8e-88,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=43.1122448979592, Blast_Score=335, Evalue=1e-92,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=44.6700507614213, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI161078106, Length=389, Percent_Identity=45.2442159383033, Blast_Score=318, Evalue=3e-87,
Organism=Drosophila melanogaster, GI24645208, Length=389, Percent_Identity=45.2442159383033, Blast_Score=318, Evalue=3e-87,
Organism=Drosophila melanogaster, GI281361397, Length=390, Percent_Identity=45.3846153846154, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI281361395, Length=390, Percent_Identity=45.3846153846154, Blast_Score=317, Evalue=9e-87,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_XYLF2 (B2I9R4)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830709.1
- ProteinModelPortal:   B2I9R4
- SMR:   B2I9R4
- GeneID:   6203385
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_2037
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41019; Mature: 41019

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFHEYQAKQLFAEYGIPVPAGRIASSADEAVTAAKSLGNGPWMVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KFCKTTDEVKQAAATMLGTKMATYQSAGVALPVNLVLVTEAGEITKELYLSVLVDRGTRS
EEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCE
ITYIASSEGGVDIEHVAAETPEKIQTLNVDFVEGLQPYQGRDIGFHLGLEAKQVNQLSKI
EEEEECCCCCCCHHHHHCCCCHHHEEECCHHHHCCCCCCCCCEEEEECCCHHHHHHHHHH
MISLYQLFNDKDLSLIELNPLAILSNGDLYALDGKINSDDNATFRHKELAAMRDKTQEDE
HHHHHHHHCCCCCEEEEECCEEEEECCCEEEECCEECCCCCCEEHHHHHHHHHCCCCCCH
TEVLASENDLNYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGATKERVTT
HHHHCCCCCCEEEEECCCEEEEEECCCEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKLILSSNKVKAIFVNIFGGIVRCDMIAEGIIAAVKEVGVKVPVIVRLEGTNVDAGKQL
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHH
LATSGLAIIPADDINDGAKKAVAAVTV
HHHCCEEEEECCCCCCCHHHHEEEECC
>Mature Secondary Structure
MNFHEYQAKQLFAEYGIPVPAGRIASSADEAVTAAKSLGNGPWMVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KFCKTTDEVKQAAATMLGTKMATYQSAGVALPVNLVLVTEAGEITKELYLSVLVDRGTRS
EEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCE
ITYIASSEGGVDIEHVAAETPEKIQTLNVDFVEGLQPYQGRDIGFHLGLEAKQVNQLSKI
EEEEECCCCCCCHHHHHCCCCHHHEEECCHHHHCCCCCCCCCEEEEECCCHHHHHHHHHH
MISLYQLFNDKDLSLIELNPLAILSNGDLYALDGKINSDDNATFRHKELAAMRDKTQEDE
HHHHHHHHCCCCCEEEEECCEEEEECCCEEEECCEECCCCCCEEHHHHHHHHHCCCCCCH
TEVLASENDLNYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGATKERVTT
HHHHCCCCCCEEEEECCCEEEEEECCCEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKLILSSNKVKAIFVNIFGGIVRCDMIAEGIIAAVKEVGVKVPVIVRLEGTNVDAGKQL
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHH
LATSGLAIIPADDINDGAKKAVAAVTV
HHHCCEEEEECCCCCCCHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA