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The map label for this gene is basS [H]

Identifier: 182682539

GI number: 182682539

Start: 2267845

End: 2269182

Strand: Direct

Name: basS [H]

Synonym: XfasM23_2027

Alternate gene names: 182682539

Gene position: 2267845-2269182 (Clockwise)

Preceding gene: 182682538

Following gene: 182682543

Centisome position: 89.44

GC content: 49.78

Gene sequence:

>1338_bases
ATGCATGAAACCGAGGCACAGTCATGTTCGAAAGGGCGACACGCGCGCTACCGGCGCCGGTTAAGAAGCCGAATCATTTT
ATCCTTCTTATTTCTTGGCTTTGCACTGACTTCGCTGTTTGCGTTTGCCACAAATTGGGCACGCGCACGGGTGGAAAACC
AGCTCGTCGAAGAATTGATGAATCGCAACATAGACGAGTATGCCAAGCGCTACTATATGGATCCATCCCATAGCCCGGAT
CTGCCAGTACAACAGATAAAAGCGTTCTACTATCCACGGGATAAATTTGACCGTGTCAGGTTAGAACGCCCTGATTGGGC
AGCACTCCCGAATGGCAATCACAATGTAATTGGCTTAGACAATGCTGGAAAACTATTTGCGTATTACAAACTCGCGGTAC
GCAAAGCCGATGATGCTTGGTTTTTCTTGGCTTACGACATGACCGAGGCTATACGTGGCGAGCGACAGCTCAAACGTGCC
CTATACATTTCTGTGCTGGTATTCAGTGGGCTGTCCCTACTTATTGGATGGTGGTCGGCCTCAAAAGTGATGAAGCCAGT
TTCAGACTTAGCTAAGCTACTACGTACTTATCGTGGTCAAACTACCAATCCAAAACCTCTCGCCCCCCACTTTCCAGATG
ATGAAGTCGGCGAGCTTGCGCGTGCATTGGACGATTATTCAAGCAAACTCACTGAAGTAGTACAAAGAGATCGTGAATTC
AACGCAGATGTGAGTCACGAATTGCGTACCCCACTGGCTGTCATCAGGGGGGCAACCGAACTGTTACTCACCAAACCCGA
AATGGACCCGAAGATCCAACAACGGATACGGCGTATTCAACGCGCCGAACAGCAATGCAGCGACCTGATTGGTGCATTGT
TACTGCTTTCGCGCAACGAACGCGGCCATGGAAGCAGCAATGTCGCCAAAGTTGCTGAACAATTACTGGATTCGCATCGC
GCCCAACTTGGCGGCAAACGAATCGAACTCATCTTGGAGGATAAACACGATCTAACGGTGAATGCACCAGAATCTGCACT
GTCAGTCGCATTGGGGAACCTGATTGGCAACGCAGTCAAGTACACCCTTGAAGGACGAGTTACGGTGCGGGTACTTGAAA
AAGCGGTCGAAATACAAGATACGGGTCCTGGTCTCAGCGAACAGGACGCTGCCAAACTATTCCAACGTGGATACCGCGGT
ACCCATGCAGGACATTCCCAAGGTGGGGGCATTGGCCTATCAATAGTGAGCCGATTATGCGATTTATACGGCTGGAAAGT
CAGCGTGCAACCAGGAGACTTCTGCGGAGTGATTGCTACATTGCGTTTCTTTAAATAA

Upstream 100 bases:

>100_bases
CGTGTGCATATCCACGGATTACGCGCCGTCGTTGATAAGCCTTTCGACGTACCATTGATACAGACTCGTCATGGGATCGG
ATACCGCATCGCCACACCCG

Downstream 100 bases:

>100_bases
CGCAATATCAAAATCAACCGCTTTAATAACCCACAATTAAAAGCAATGAGAGTATCCAAGAAACATTAATCAGCGGATCG
AAGCAACTCATACATCCATA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MHETEAQSCSKGRHARYRRRLRSRIILSFLFLGFALTSLFAFATNWARARVENQLVEELMNRNIDEYAKRYYMDPSHSPD
LPVQQIKAFYYPRDKFDRVRLERPDWAALPNGNHNVIGLDNAGKLFAYYKLAVRKADDAWFFLAYDMTEAIRGERQLKRA
LYISVLVFSGLSLLIGWWSASKVMKPVSDLAKLLRTYRGQTTNPKPLAPHFPDDEVGELARALDDYSSKLTEVVQRDREF
NADVSHELRTPLAVIRGATELLLTKPEMDPKIQQRIRRIQRAEQQCSDLIGALLLLSRNERGHGSSNVAKVAEQLLDSHR
AQLGGKRIELILEDKHDLTVNAPESALSVALGNLIGNAVKYTLEGRVTVRVLEKAVEIQDTGPGLSEQDAAKLFQRGYRG
THAGHSQGGGIGLSIVSRLCDLYGWKVSVQPGDFCGVIATLRFFK

Sequences:

>Translated_445_residues
MHETEAQSCSKGRHARYRRRLRSRIILSFLFLGFALTSLFAFATNWARARVENQLVEELMNRNIDEYAKRYYMDPSHSPD
LPVQQIKAFYYPRDKFDRVRLERPDWAALPNGNHNVIGLDNAGKLFAYYKLAVRKADDAWFFLAYDMTEAIRGERQLKRA
LYISVLVFSGLSLLIGWWSASKVMKPVSDLAKLLRTYRGQTTNPKPLAPHFPDDEVGELARALDDYSSKLTEVVQRDREF
NADVSHELRTPLAVIRGATELLLTKPEMDPKIQQRIRRIQRAEQQCSDLIGALLLLSRNERGHGSSNVAKVAEQLLDSHR
AQLGGKRIELILEDKHDLTVNAPESALSVALGNLIGNAVKYTLEGRVTVRVLEKAVEIQDTGPGLSEQDAAKLFQRGYRG
THAGHSQGGGIGLSIVSRLCDLYGWKVSVQPGDFCGVIATLRFFK
>Mature_445_residues
MHETEAQSCSKGRHARYRRRLRSRIILSFLFLGFALTSLFAFATNWARARVENQLVEELMNRNIDEYAKRYYMDPSHSPD
LPVQQIKAFYYPRDKFDRVRLERPDWAALPNGNHNVIGLDNAGKLFAYYKLAVRKADDAWFFLAYDMTEAIRGERQLKRA
LYISVLVFSGLSLLIGWWSASKVMKPVSDLAKLLRTYRGQTTNPKPLAPHFPDDEVGELARALDDYSSKLTEVVQRDREF
NADVSHELRTPLAVIRGATELLLTKPEMDPKIQQRIRRIQRAEQQCSDLIGALLLLSRNERGHGSSNVAKVAEQLLDSHR
AQLGGKRIELILEDKHDLTVNAPESALSVALGNLIGNAVKYTLEGRVTVRVLEKAVEIQDTGPGLSEQDAAKLFQRGYRG
THAGHSQGGGIGLSIVSRLCDLYGWKVSVQPGDFCGVIATLRFFK

Specific function: Member of the two-component regulatory system BasS/BasR Autophosphorylates and activates BasR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=291, Percent_Identity=28.8659793814433, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790861, Length=307, Percent_Identity=29.6416938110749, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788393, Length=241, Percent_Identity=28.6307053941909, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=31.4410480349345, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789403, Length=274, Percent_Identity=28.8321167883212, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1786600, Length=204, Percent_Identity=30.8823529411765, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788279, Length=219, Percent_Identity=27.8538812785388, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788713, Length=349, Percent_Identity=26.647564469914, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790346, Length=205, Percent_Identity=30.7317073170732, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=23.448275862069, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=29.1304347826087, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=25.3218884120172, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50238; Mature: 50238

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHETEAQSCSKGRHARYRRRLRSRIILSFLFLGFALTSLFAFATNWARARVENQLVEELM
CCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRNIDEYAKRYYMDPSHSPDLPVQQIKAFYYPRDKFDRVRLERPDWAALPNGNHNVIGLD
HCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCEEEEC
NAGKLFAYYKLAVRKADDAWFFLAYDMTEAIRGERQLKRALYISVLVFSGLSLLIGWWSA
CCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKVMKPVSDLAKLLRTYRGQTTNPKPLAPHFPDDEVGELARALDDYSSKLTEVVQRDREF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
NADVSHELRTPLAVIRGATELLLTKPEMDPKIQQRIRRIQRAEQQCSDLIGALLLLSRNE
CCCHHHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RGHGSSNVAKVAEQLLDSHRAQLGGKRIELILEDKHDLTVNAPESALSVALGNLIGNAVK
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHE
YTLEGRVTVRVLEKAVEIQDTGPGLSEQDAAKLFQRGYRGTHAGHSQGGGIGLSIVSRLC
EEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
DLYGWKVSVQPGDFCGVIATLRFFK
HHHCCEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MHETEAQSCSKGRHARYRRRLRSRIILSFLFLGFALTSLFAFATNWARARVENQLVEELM
CCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRNIDEYAKRYYMDPSHSPDLPVQQIKAFYYPRDKFDRVRLERPDWAALPNGNHNVIGLD
HCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCEEEEC
NAGKLFAYYKLAVRKADDAWFFLAYDMTEAIRGERQLKRALYISVLVFSGLSLLIGWWSA
CCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKVMKPVSDLAKLLRTYRGQTTNPKPLAPHFPDDEVGELARALDDYSSKLTEVVQRDREF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
NADVSHELRTPLAVIRGATELLLTKPEMDPKIQQRIRRIQRAEQQCSDLIGALLLLSRNE
CCCHHHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RGHGSSNVAKVAEQLLDSHRAQLGGKRIELILEDKHDLTVNAPESALSVALGNLIGNAVK
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHE
YTLEGRVTVRVLEKAVEIQDTGPGLSEQDAAKLFQRGYRGTHAGHSQGGGIGLSIVSRLC
EEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
DLYGWKVSVQPGDFCGVIATLRFFK
HHHCCEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 7610040; 9278503 [H]