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The map label for this gene is bga [H]

Identifier: 182682446

GI number: 182682446

Start: 2160324

End: 2162162

Strand: Direct

Name: bga [H]

Synonym: XfasM23_1933

Alternate gene names: 182682446

Gene position: 2160324-2162162 (Clockwise)

Preceding gene: 182682445

Following gene: 182682450

Centisome position: 85.2

GC content: 58.51

Gene sequence:

>1839_bases
ATGCTGCGTCACCTGCTCACGTTGTCGCTGATATTCGCAATCGTGCTGCCCATTGGAGTTAGCGCCGCGCCTTGGCCTGC
TTTTTCAACTCGGGGAACGCAATTCATCCGTGATGGGAGGCCGTATCAGTTGATCTCGGGTGCCATCCACTTCCAACGCA
TCCCGCGGGCGTACTGGAAGGACCGTTTGCAAAAAGCCCGAGCAATGGGGTTGAACACGGTGGAAACCTATGTTTTCTGG
AACCTGGTTGAACTCCGTGAAGGTCAATTCGACTTCACAGGGAATAACGACATTGGTGCTTTTGTGCGTGAAGCAGCGTC
GCAAGGTCTGAACGTGATTCTGCGTCCCGGGCCATATGTGTGTGCAGAATGGGAGGCAGGGGGGTTCCCAGCGTGGCTGT
TCGCCGATCCAACGCTACGGGTGCGCAGTCAGGATCCGCGTTTTCTTGATGCCAGTCAGCGCTATCTGGAGGCACTCGGC
ACACAGGTCAGGCCGCTGCTCAATGGCAATGGCGGTCCCATCATTGCAGTGCAGGTTGAGAATGAGTACGGCTCTTATGG
GGATGATCATGGCTATCTACAGGCTGTGCGCGCGCTATTCATCAAGGCCGGTTTGGGAGGTGCGCTGTTGTTTACCGCCG
ACGGGGCTCAGATGCTTGGCAATGGCACGCTGCCGGACGTGCTGGCGGCGGTGAATGTCGCACCGGGTGAGGCAAAACAG
GCGCTCGACAAGCTCGCCACATTCCATCCTGGGCAGCCGCAGCTGGTGGGTGAATATTGGGCGGGGTGGTTCGACCAGTG
GGGCAAGCCGCATGCGCAGACTGATGCAAAGCAGCAGGCTGATGAGATCGAATGGATGTTGCGGCAAGGGCATTCGATCA
ATCTGTATATGTTTGTTGGCGGCACCAGTTTTGGTTTTATGAATGGTGCTAACTTCCAAGGTGGTCCCAGTGACCATTAC
AGCCCTCAAACCACAAGCTACGATTACGATGCGGTGTTGGACGAAGCCGGACGGCCGATGCCGAAGTTCGCGCTGTTCCG
CGATGTCATCACCCGTGTGACTGGTCTCCAGCCGCCGCCTTTGCCAGCGGCAAGCCGTTTTATCGATTTGCCGGACACGC
CATTGCGCGCATCCGCTTCGCTCTGGGACAACCTGCCTGCAGCGGTCGCCACCACAGCAGATCCGCAGCCGATGGAGCGC
TATGGGCAGGCCTACGGTTACATTTTGTACCGCACCACGCTCCACGGGCCACGGAAGGGCAGGCTGTATCTGGGTGAGGT
GCGGGATGACGCCCATGTCTACGTTGATCGTCTCTTCGTGGGTCGGGCGGAACGGCGTCGGCAGCAGGTCTGGGTGGAGG
TTGACATTCCCTCCGGTACTCACTGTCTGGATGTCTTGGTAGAAAACAGTGGACGGGTTAACTACGGTCCGCACCTGGCT
GACGGCCGCGCCGGGCTGATTGGTCCGGTGATGCTCAATCATGAACGCGTCAACAATTGGGAAACGTTCCTGCTGCCGTT
GCAGACGCCCGAAGCGATCCACGGTTGGACAACCGCACCGATGCAAGGACCTGCTTTTCATCGTGGCACGTTGTTTATCC
GCACGCCTGGAGACACATTTTTGGATATGGAGGCTTTCAGCAAGGGGGTGACCTGGGCCAATGGTCACATGCTTGGCCGC
TACTGGGACATCGGCCCGCAGCGGGCGCTTTACTTCCCGGGGGCGTGGCAGCGCCAAGGGGAGAATACGGTGCTCGTCTT
CGATGTGAGCGATACGGCAGCAGCACAGGTACGCGGTGTGCAGCAGCAACGCTGGATCACTCCAAGGACGGCCAAATAA

Upstream 100 bases:

>100_bases
GATGCCCGGTCTTCTGATTTTTCCATTGAACGACAGCGCTTCATCCGACTGGCGATGCTGGATCGGATCACGCCACGTTT
TCCCTCTTTGAGACATACCC

Downstream 100 bases:

>100_bases
TGTTCTGCAGCAGCAGAGACGCTGCTGGGCATGGGTCTTGTCTGTTTGCACGCTCTCATGAGAGGTAAGGCTTGCTCGGC
AATACCAGAGGCAAGGGAAA

Product: beta-galactosidase

Products: NA

Alternate protein names: Lactase [H]

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MLRHLLTLSLIFAIVLPIGVSAAPWPAFSTRGTQFIRDGRPYQLISGAIHFQRIPRAYWKDRLQKARAMGLNTVETYVFW
NLVELREGQFDFTGNNDIGAFVREAASQGLNVILRPGPYVCAEWEAGGFPAWLFADPTLRVRSQDPRFLDASQRYLEALG
TQVRPLLNGNGGPIIAVQVENEYGSYGDDHGYLQAVRALFIKAGLGGALLFTADGAQMLGNGTLPDVLAAVNVAPGEAKQ
ALDKLATFHPGQPQLVGEYWAGWFDQWGKPHAQTDAKQQADEIEWMLRQGHSINLYMFVGGTSFGFMNGANFQGGPSDHY
SPQTTSYDYDAVLDEAGRPMPKFALFRDVITRVTGLQPPPLPAASRFIDLPDTPLRASASLWDNLPAAVATTADPQPMER
YGQAYGYILYRTTLHGPRKGRLYLGEVRDDAHVYVDRLFVGRAERRRQQVWVEVDIPSGTHCLDVLVENSGRVNYGPHLA
DGRAGLIGPVMLNHERVNNWETFLLPLQTPEAIHGWTTAPMQGPAFHRGTLFIRTPGDTFLDMEAFSKGVTWANGHMLGR
YWDIGPQRALYFPGAWQRQGENTVLVFDVSDTAAAQVRGVQQQRWITPRTAK

Sequences:

>Translated_612_residues
MLRHLLTLSLIFAIVLPIGVSAAPWPAFSTRGTQFIRDGRPYQLISGAIHFQRIPRAYWKDRLQKARAMGLNTVETYVFW
NLVELREGQFDFTGNNDIGAFVREAASQGLNVILRPGPYVCAEWEAGGFPAWLFADPTLRVRSQDPRFLDASQRYLEALG
TQVRPLLNGNGGPIIAVQVENEYGSYGDDHGYLQAVRALFIKAGLGGALLFTADGAQMLGNGTLPDVLAAVNVAPGEAKQ
ALDKLATFHPGQPQLVGEYWAGWFDQWGKPHAQTDAKQQADEIEWMLRQGHSINLYMFVGGTSFGFMNGANFQGGPSDHY
SPQTTSYDYDAVLDEAGRPMPKFALFRDVITRVTGLQPPPLPAASRFIDLPDTPLRASASLWDNLPAAVATTADPQPMER
YGQAYGYILYRTTLHGPRKGRLYLGEVRDDAHVYVDRLFVGRAERRRQQVWVEVDIPSGTHCLDVLVENSGRVNYGPHLA
DGRAGLIGPVMLNHERVNNWETFLLPLQTPEAIHGWTTAPMQGPAFHRGTLFIRTPGDTFLDMEAFSKGVTWANGHMLGR
YWDIGPQRALYFPGAWQRQGENTVLVFDVSDTAAAQVRGVQQQRWITPRTAK
>Mature_612_residues
MLRHLLTLSLIFAIVLPIGVSAAPWPAFSTRGTQFIRDGRPYQLISGAIHFQRIPRAYWKDRLQKARAMGLNTVETYVFW
NLVELREGQFDFTGNNDIGAFVREAASQGLNVILRPGPYVCAEWEAGGFPAWLFADPTLRVRSQDPRFLDASQRYLEALG
TQVRPLLNGNGGPIIAVQVENEYGSYGDDHGYLQAVRALFIKAGLGGALLFTADGAQMLGNGTLPDVLAAVNVAPGEAKQ
ALDKLATFHPGQPQLVGEYWAGWFDQWGKPHAQTDAKQQADEIEWMLRQGHSINLYMFVGGTSFGFMNGANFQGGPSDHY
SPQTTSYDYDAVLDEAGRPMPKFALFRDVITRVTGLQPPPLPAASRFIDLPDTPLRASASLWDNLPAAVATTADPQPMER
YGQAYGYILYRTTLHGPRKGRLYLGEVRDDAHVYVDRLFVGRAERRRQQVWVEVDIPSGTHCLDVLVENSGRVNYGPHLA
DGRAGLIGPVMLNHERVNNWETFLLPLQTPEAIHGWTTAPMQGPAFHRGTLFIRTPGDTFLDMEAFSKGVTWANGHMLGR
YWDIGPQRALYFPGAWQRQGENTVLVFDVSDTAAAQVRGVQQQRWITPRTAK

Specific function: Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages [H]

COG id: COG1874

COG function: function code G; Beta-galactosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 35 family [H]

Homologues:

Organism=Homo sapiens, GI31543093, Length=577, Percent_Identity=41.421143847487, Blast_Score=404, Evalue=1e-112,
Organism=Homo sapiens, GI164519026, Length=574, Percent_Identity=38.3275261324042, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI119372312, Length=593, Percent_Identity=37.0994940978078, Blast_Score=347, Evalue=2e-95,
Organism=Homo sapiens, GI119372308, Length=593, Percent_Identity=37.0994940978078, Blast_Score=347, Evalue=2e-95,
Organism=Homo sapiens, GI40255043, Length=586, Percent_Identity=37.8839590443686, Blast_Score=345, Evalue=6e-95,
Organism=Homo sapiens, GI208022658, Length=434, Percent_Identity=31.1059907834101, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI72000600, Length=613, Percent_Identity=33.605220228385, Blast_Score=286, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI17568491, Length=634, Percent_Identity=31.3880126182965, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24646169, Length=595, Percent_Identity=36.1344537815126, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24582088, Length=631, Percent_Identity=32.9635499207607, Blast_Score=313, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR019801
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR001944 [H]

Pfam domain/function: PF01301 Glyco_hydro_35 [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 67993; Mature: 67993

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS01182 GLYCOSYL_HYDROL_F35

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRHLLTLSLIFAIVLPIGVSAAPWPAFSTRGTQFIRDGRPYQLISGAIHFQRIPRAYWK
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCHHHHH
DRLQKARAMGLNTVETYVFWNLVELREGQFDFTGNNDIGAFVREAASQGLNVILRPGPYV
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCEEEECCCCEE
CAEWEAGGFPAWLFADPTLRVRSQDPRFLDASQRYLEALGTQVRPLLNGNGGPIIAVQVE
EEECCCCCCEEEEEECCEEEEECCCCCEECHHHHHHHHHCHHHCEEECCCCCEEEEEEEC
NEYGSYGDDHGYLQAVRALFIKAGLGGALLFTADGAQMLGNGTLPDVLAAVNVAPGEAKQ
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHCCCCHHHHHHHHCCCCCHHHH
ALDKLATFHPGQPQLVGEYWAGWFDQWGKPHAQTDAKQQADEIEWMLRQGHSINLYMFVG
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEC
GTSFGFMNGANFQGGPSDHYSPQTTSYDYDAVLDEAGRPMPKFALFRDVITRVTGLQPPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
LPAASRFIDLPDTPLRASASLWDNLPAAVATTADPQPMERYGQAYGYILYRTTLHGPRKG
CCHHHHEECCCCCCCCCCHHHHHCCCCCEEECCCCHHHHHHCCHHEEEEEEEECCCCCCC
RLYLGEVRDDAHVYVDRLFVGRAERRRQQVWVEVDIPSGTHCLDVLVENSGRVNYGPHLA
CEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCC
DGRAGLIGPVMLNHERVNNWETFLLPLQTPEAIHGWTTAPMQGPAFHRGTLFIRTPGDTF
CCCCCCCCCEEECCHHCCCCEEEEEEECCCCHHCCCCCCCCCCCCEECCEEEEECCCCCE
LDMEAFSKGVTWANGHMLGRYWDIGPQRALYFPGAWQRQGENTVLVFDVSDTAAAQVRGV
EEHHHHHCCCEEECCEEEEEEECCCCCCEEECCCCCCCCCCCEEEEEECCCHHHHHHHCC
QQQRWITPRTAK
HHHHCCCCCCCC
>Mature Secondary Structure
MLRHLLTLSLIFAIVLPIGVSAAPWPAFSTRGTQFIRDGRPYQLISGAIHFQRIPRAYWK
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCHHHHH
DRLQKARAMGLNTVETYVFWNLVELREGQFDFTGNNDIGAFVREAASQGLNVILRPGPYV
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCEEEECCCCEE
CAEWEAGGFPAWLFADPTLRVRSQDPRFLDASQRYLEALGTQVRPLLNGNGGPIIAVQVE
EEECCCCCCEEEEEECCEEEEECCCCCEECHHHHHHHHHCHHHCEEECCCCCEEEEEEEC
NEYGSYGDDHGYLQAVRALFIKAGLGGALLFTADGAQMLGNGTLPDVLAAVNVAPGEAKQ
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHCCCCHHHHHHHHCCCCCHHHH
ALDKLATFHPGQPQLVGEYWAGWFDQWGKPHAQTDAKQQADEIEWMLRQGHSINLYMFVG
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEC
GTSFGFMNGANFQGGPSDHYSPQTTSYDYDAVLDEAGRPMPKFALFRDVITRVTGLQPPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
LPAASRFIDLPDTPLRASASLWDNLPAAVATTADPQPMERYGQAYGYILYRTTLHGPRKG
CCHHHHEECCCCCCCCCCHHHHHCCCCCEEECCCCHHHHHHCCHHEEEEEEEECCCCCCC
RLYLGEVRDDAHVYVDRLFVGRAERRRQQVWVEVDIPSGTHCLDVLVENSGRVNYGPHLA
CEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCC
DGRAGLIGPVMLNHERVNNWETFLLPLQTPEAIHGWTTAPMQGPAFHRGTLFIRTPGDTF
CCCCCCCCCEEECCHHCCCCEEEEEEECCCCHHCCCCCCCCCCCCEECCEEEEECCCCCE
LDMEAFSKGVTWANGHMLGRYWDIGPQRALYFPGAWQRQGENTVLVFDVSDTAAAQVRGV
EEHHHHHCCCEEECCEEEEEEECCCCCCEEECCCCCCCCCCCEEEEEECCCHHHHHHHCC
QQQRWITPRTAK
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8563148 [H]