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The map label for this gene is ubiH [H]

Identifier: 182682450

GI number: 182682450

Start: 2167785

End: 2168993

Strand: Direct

Name: ubiH [H]

Synonym: XfasM23_1937

Alternate gene names: 182682450

Gene position: 2167785-2168993 (Clockwise)

Preceding gene: 182682446

Following gene: 182682451

Centisome position: 85.49

GC content: 61.62

Gene sequence:

>1209_bases
ATGAATCAGCTCCATGATGTTTTGATTGTCGGCGGCGGTTTGGTCGGCGCCAGCCTCGCGATTGCCCTGGACCAGATCGG
CATGAACATTGGCCTGGTTGAAGTCACACCACCGGGGGCGCTACCCACGGTATTCGATGAGCGTACCCTCTGTTTCGCCG
CAGCCACAGTAAACGCTTTAGACGCCCTCAATGTCATGACACGGATACGCCACGCCGCCGGCCCCATCCGGCGTATCCAC
GCCAGCCGCACCGGCGACTTCGGCCGCGTGCGATTGGACGCCTCGACCTACGGACGTGACGCCTTCGGCCAAGTAGTCAT
TGCACGTGATTTCGGCGAAGCGTTGGAACACCGCCTCACCGAACTCAAACAACTCACCCGCTACCGCCCAGCACGCTGCA
TCGCCGTGACGCCCGTGACCGATGGCATGCGCGGCGTACGGATCGCCCATGCCGATGGCGAACAGCTCTTACATGCACGC
CTGATCGTCGGTGCAGATGGCACACAGAGCACCGTACGCGAACTGCTGCATATCGACACCACACAACACGATTACTTCCA
AACACTTTTCGTCGCACGGGTGCAAACCACTCAAGCACCCGACGGAACCGCTTACGAACGTTTCACCGAACACGGCCCCA
CGGCCCTGCTGCCTCGCGCCGACCGTCACTATGGCGCCATTCATTGCGTCGCCCGTACCCAGGCCAATACAGTCGCTGCC
CTGGATGACAGCGCCTGGCTGACACGGCTGCAACACGCCATGGGCTGGCGCGCTGGTCGCTTCATTGCCAGTAGCGCACG
CAGCGCCTACCCATTGATGCAAGTGATCGCACAAGATCTGACCGCCGAACGCGTGGCACTGCTCGGCAACGCCGCACAGA
CACTGCACCCCATAGGAGCCCAAGGCTTCAACCTGGGCCTGCGCGATGCACTCACCTTGGCTGAAATGATCGCCGCCGAT
CACACCGACCCCGGCGCAACCGCACTGCTCACCGCCTATACCGCACGACGGCGTGCAGACCGCGAACAGACACTCATGTT
CTCTAACGGCTTAGCACAACTCACCAGCAATGGATTGCCGCTGCTGCGACCGCTACGCAGTCTCGGCCTGCTTGCCGTCT
CCCACATCAGCGAGCTGCAAGCACTCCTGGTCAACGGCGCGATGGGCTTCCGTGGCGACGTACCGCAATTGTGTCTCAAC
AGCGTATGA

Upstream 100 bases:

>100_bases
CATTCCTATGCAATAGACAGCACCTCATGATGCTGCCCACTTTGGCAGACGAACCCACACCCAGGCCCACTGCCAAGAGA
GGAAGGCTTATCATGGCGGC

Downstream 100 bases:

>100_bases
ACCGAACTCAGCGACCGGATGTACTCATCACTGGCGGCGGCGTCGTCGGTGCCAGCAGCGCCCTGGCATTGGCGAAAACA
GGGTTACACGTCGCCTTGAT

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MNQLHDVLIVGGGLVGASLAIALDQIGMNIGLVEVTPPGALPTVFDERTLCFAAATVNALDALNVMTRIRHAAGPIRRIH
ASRTGDFGRVRLDASTYGRDAFGQVVIARDFGEALEHRLTELKQLTRYRPARCIAVTPVTDGMRGVRIAHADGEQLLHAR
LIVGADGTQSTVRELLHIDTTQHDYFQTLFVARVQTTQAPDGTAYERFTEHGPTALLPRADRHYGAIHCVARTQANTVAA
LDDSAWLTRLQHAMGWRAGRFIASSARSAYPLMQVIAQDLTAERVALLGNAAQTLHPIGAQGFNLGLRDALTLAEMIAAD
HTDPGATALLTAYTARRRADREQTLMFSNGLAQLTSNGLPLLRPLRSLGLLAVSHISELQALLVNGAMGFRGDVPQLCLN
SV

Sequences:

>Translated_402_residues
MNQLHDVLIVGGGLVGASLAIALDQIGMNIGLVEVTPPGALPTVFDERTLCFAAATVNALDALNVMTRIRHAAGPIRRIH
ASRTGDFGRVRLDASTYGRDAFGQVVIARDFGEALEHRLTELKQLTRYRPARCIAVTPVTDGMRGVRIAHADGEQLLHAR
LIVGADGTQSTVRELLHIDTTQHDYFQTLFVARVQTTQAPDGTAYERFTEHGPTALLPRADRHYGAIHCVARTQANTVAA
LDDSAWLTRLQHAMGWRAGRFIASSARSAYPLMQVIAQDLTAERVALLGNAAQTLHPIGAQGFNLGLRDALTLAEMIAAD
HTDPGATALLTAYTARRRADREQTLMFSNGLAQLTSNGLPLLRPLRSLGLLAVSHISELQALLVNGAMGFRGDVPQLCLN
SV
>Mature_402_residues
MNQLHDVLIVGGGLVGASLAIALDQIGMNIGLVEVTPPGALPTVFDERTLCFAAATVNALDALNVMTRIRHAAGPIRRIH
ASRTGDFGRVRLDASTYGRDAFGQVVIARDFGEALEHRLTELKQLTRYRPARCIAVTPVTDGMRGVRIAHADGEQLLHAR
LIVGADGTQSTVRELLHIDTTQHDYFQTLFVARVQTTQAPDGTAYERFTEHGPTALLPRADRHYGAIHCVARTQANTVAA
LDDSAWLTRLQHAMGWRAGRFIASSARSAYPLMQVIAQDLTAERVALLGNAAQTLHPIGAQGFNLGLRDALTLAEMIAAD
HTDPGATALLTAYTARRRADREQTLMFSNGLAQLTSNGLPLLRPLRSLGLLAVSHISELQALLVNGAMGFRGDVPQLCLN
SV

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967307, Length=310, Percent_Identity=28.0645161290323, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI32967305, Length=310, Percent_Identity=28.0645161290323, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1789274, Length=393, Percent_Identity=35.3689567430025, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1786883, Length=400, Percent_Identity=28, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789273, Length=398, Percent_Identity=28.894472361809, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25146631, Length=437, Percent_Identity=22.6544622425629, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 43346; Mature: 43346

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLHDVLIVGGGLVGASLAIALDQIGMNIGLVEVTPPGALPTVFDERTLCFAAATVNAL
CCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHCCCHHHHHHHHHHHH
DALNVMTRIRHAAGPIRRIHASRTGDFGRVRLDASTYGRDAFGQVVIARDFGEALEHRLT
HHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEECHHHCCCCCCCCEEEEHHHHHHHHHHHH
ELKQLTRYRPARCIAVTPVTDGMRGVRIAHADGEQLLHARLIVGADGTQSTVRELLHIDT
HHHHHHHCCCCEEEEEECCCCCCCCEEEEECCHHHHEEEEEEEECCCCHHHHHHHHHCCC
TQHDYFQTLFVARVQTTQAPDGTAYERFTEHGPTALLPRADRHYGAIHCVARTQANTVAA
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEECCCCCCCCCEEEEEEECCCCEEEE
LDDSAWLTRLQHAMGWRAGRFIASSARSAYPLMQVIAQDLTAERVALLGNAAQTLHPIGA
ECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCC
QGFNLGLRDALTLAEMIAADHTDPGATALLTAYTARRRADREQTLMFSNGLAQLTSNGLP
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCCCH
LLRPLRSLGLLAVSHISELQALLVNGAMGFRGDVPQLCLNSV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MNQLHDVLIVGGGLVGASLAIALDQIGMNIGLVEVTPPGALPTVFDERTLCFAAATVNAL
CCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHCCCHHHHHHHHHHHH
DALNVMTRIRHAAGPIRRIHASRTGDFGRVRLDASTYGRDAFGQVVIARDFGEALEHRLT
HHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEECHHHCCCCCCCCEEEEHHHHHHHHHHHH
ELKQLTRYRPARCIAVTPVTDGMRGVRIAHADGEQLLHARLIVGADGTQSTVRELLHIDT
HHHHHHHCCCCEEEEEECCCCCCCCEEEEECCHHHHEEEEEEEECCCCHHHHHHHHHCCC
TQHDYFQTLFVARVQTTQAPDGTAYERFTEHGPTALLPRADRHYGAIHCVARTQANTVAA
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEECCCCCCCCCEEEEEEECCCCEEEE
LDDSAWLTRLQHAMGWRAGRFIASSARSAYPLMQVIAQDLTAERVALLGNAAQTLHPIGA
ECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCC
QGFNLGLRDALTLAEMIAADHTDPGATALLTAYTARRRADREQTLMFSNGLAQLTSNGLP
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCCCH
LLRPLRSLGLLAVSHISELQALLVNGAMGFRGDVPQLCLNSV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]