| Definition | Xylella fastidiosa M23 chromosome, complete genome. |
|---|---|
| Accession | NC_010577 |
| Length | 2,535,690 |
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The map label for this gene is mrcA [H]
Identifier: 182682307
GI number: 182682307
Start: 1987445
End: 1989874
Strand: Direct
Name: mrcA [H]
Synonym: XfasM23_1790
Alternate gene names: 182682307
Gene position: 1987445-1989874 (Clockwise)
Preceding gene: 182682299
Following gene: 182682309
Centisome position: 78.38
GC content: 51.4
Gene sequence:
>2430_bases ATGTATCGTCTCCGCGGTTGGCTTGGGTGGCTCCTCACCATACTTATCATCCTCACACTCGTTGGCATCCTGGCAGCGGG CAGTATGTATTACGCCATTTCCTCGAAACTGCCCGACATTCGAAACCTCAAACAAGTCGAACTACAAGAACCAATGTACG TCTACTCCCACGATGGCCTGTTGATAGCGATATTCGGAGAAATCCGCCGCTACCCTGTGCAGATCAAGGAAGTGCCTGAG CAACTTAAACAAGCATTCCTAGCGACCGAAGACGCTCGTTTCTACGAACACAGCGGCATTGACTATAAAGGAATTGCACG CGCAATTTGGCTACTAGCGACAACAAACGAAAAACGTGTCCCAGGTGGTTCAACGATTACTCAACAGGTTGCCCGCCAAT TCTTTCTCAACTCCGAATACAGCTATAAACGCAAACTGGCTGAAATTCTATTAGCTCGAAAAATAGAGTCGCAGTTAAAG AAAGACGAAATCCTGGAGCTGTATCTAAACAAAAGTTTTTTCGGAAACCGTGCCTACGGCATCGCTGCTGCAGCCGAGTT TTACTACGGCAAGAAACTAAACGAACTTAACCTTGATGAGATGGCATCCTTAGCTGGGATCCCCAAATTTCCATCAAGCG GCAACCCGATTACCAACCCGGCTCGTGCCCGCGAACGGCGTGATTTATACGTACTACAACGCATGGTCGACCTTAACTTC ATCACCCAAGACCAAGCCAATGCCGCAAAAGCAATACCGATGCACGCCAAACCCCACGAACCACCAGTCCAGGTATACGC CCCCTACGCAGCCGAAATGGTACGTCAGGAAATGATCGCCAAATACGGTGGTGCCGCACTCAACAAAGGCTATCACGTCA CCACCACGATTGATGGCACACTTCAAATGGCCGCCGAAACTTCCGTACGCAACGGCCTAGCGTTATATGAACATCGCCAC CGTTGGCGAGGTGCCGAACAACATATCGAAGTGGATGCAAACGCAGACACAGCTACATTAGCTGCACACCTGTCAGGCAT TTCCTCCCAAGGTGGGATGTTCCCAGTGATCGTGGCACGTACCACTCCCGAAGGCAGCGCCATCGTGGTACGTAGTGATC GCAGCGAATTGACGCTCCCCCCGGCAGCCTCGCGCTGGACCGGCACTCCACTGAACAAACTCCTCAAACGTGGTGACGTG GTGCGGGTCAGGCCTGGGGAAAAACGGGGTGAATGGACATTAGAACAGCTACCCAGCGCTCAATCCACATTGGTCTCACT AGATGCCAACAATGGCGCACTACGTGCACTCGTCGGTGGCTTCAGCTTCACCGCTAATAAATTCAATCGCGCCACCCAAG CACGCCGCCAACCTGGGTCGAGCTTCAAGCCATTCGTCTATTCAGCCGCATTAGAAAAAGGCTTCAATCCAGCGTCCATC GTACCGGATGCACCTGTCATATTCCGCGATCGCCGCGGCCATACCTGGTCGCCACAGAACGATGACGGCAAATTCCAAGG TCCAATGCGTATCCGTGACGCCCTGGTTCAATCACGCAACCTAGTATCAGTACGACTACTCGACGCAATCGGCATAGATT TTGCACGCAACTACATTACCCAATTCGGTTTTGAGGAAAACGAGATTCCTCCAAACTTATCAATGTCTCTGGGTACAGCC TCACTCACTCCATTGTCGATCGCGCGCGGTTACGCAGTATTTGCAAACGGCGGCTTCCGCATCGACCCTTGGCTTATTGA CGAGATACACGACAGAGAACACAAATTAATCTTCAAGAACAACCCTAAGGTAGCCTGTAGCAGCTGCACGTCGGCCAACA CCAACGTCACTCAATCAACCAGCCACCTAGTGGACGGATTCAACTTTGGCGCACCCACCAAAACAGAACCATCCAAACCA GTAAAAAACAACAACGAACCTACCCAGACCATCCCTTCACCGGATCCCAACACCCCAATGGCACCGCGCGCGATTGATGA ACGCGTTGTCTTCCAATTGGTATCAATGATGCGCGACGTGGTGCTACGCGGTACAGCAACCGCAGCACGCTCACTGAATC GCCAGGACATCGCCGGAAAAACTGGCTCAACCAACGAACACCGTGATGCGTGGTTCTCAGGGTTTGGCGGACCTTATGTA ACTACCGTATGGGTAGGACGCGATGACTTCCAGTCACTTGGTTACAGAGAGTATGGCGGTAAAGCAGCACTCCCCATCTG GATCGAATATATGCGCACTGCATTGAAGGACAAACCAATCGCACGCAACGCCCCCCCTCAAGGCATGACTCAAACCACAC TCAACGGAGCAACCGAATGGGTCAAAAACGAAGATATAAACCACTTACAAGATCATGATTTCAAGTTGCATGAAGAAGAA AGTGATGAACAGACCTTTGACATCTTCTGA
Upstream 100 bases:
>100_bases CATTTGTTTTTTAACAATTAGAAATTCTAAGGCAATGCCAAAGCCTAAGCTCATCTATACTCTACGGCCAAAAAGTTCGC AATCCAATATCGATTTAAAT
Downstream 100 bases:
>100_bases TTCTGCCCCGAGCCAACACACATTCATTACGTAGGACTAAATATCACTTAGGTAAAAAACCAACTGCCCTCTAACAGCAT TTAGCAAAGACATTCCCCAT
Product: 1A family penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 809; Mature: 809
Protein sequence:
>809_residues MYRLRGWLGWLLTILIILTLVGILAAGSMYYAISSKLPDIRNLKQVELQEPMYVYSHDGLLIAIFGEIRRYPVQIKEVPE QLKQAFLATEDARFYEHSGIDYKGIARAIWLLATTNEKRVPGGSTITQQVARQFFLNSEYSYKRKLAEILLARKIESQLK KDEILELYLNKSFFGNRAYGIAAAAEFYYGKKLNELNLDEMASLAGIPKFPSSGNPITNPARARERRDLYVLQRMVDLNF ITQDQANAAKAIPMHAKPHEPPVQVYAPYAAEMVRQEMIAKYGGAALNKGYHVTTTIDGTLQMAAETSVRNGLALYEHRH RWRGAEQHIEVDANADTATLAAHLSGISSQGGMFPVIVARTTPEGSAIVVRSDRSELTLPPAASRWTGTPLNKLLKRGDV VRVRPGEKRGEWTLEQLPSAQSTLVSLDANNGALRALVGGFSFTANKFNRATQARRQPGSSFKPFVYSAALEKGFNPASI VPDAPVIFRDRRGHTWSPQNDDGKFQGPMRIRDALVQSRNLVSVRLLDAIGIDFARNYITQFGFEENEIPPNLSMSLGTA SLTPLSIARGYAVFANGGFRIDPWLIDEIHDREHKLIFKNNPKVACSSCTSANTNVTQSTSHLVDGFNFGAPTKTEPSKP VKNNNEPTQTIPSPDPNTPMAPRAIDERVVFQLVSMMRDVVLRGTATAARSLNRQDIAGKTGSTNEHRDAWFSGFGGPYV TTVWVGRDDFQSLGYREYGGKAALPIWIEYMRTALKDKPIARNAPPQGMTQTTLNGATEWVKNEDINHLQDHDFKLHEEE SDEQTFDIF
Sequences:
>Translated_809_residues MYRLRGWLGWLLTILIILTLVGILAAGSMYYAISSKLPDIRNLKQVELQEPMYVYSHDGLLIAIFGEIRRYPVQIKEVPE QLKQAFLATEDARFYEHSGIDYKGIARAIWLLATTNEKRVPGGSTITQQVARQFFLNSEYSYKRKLAEILLARKIESQLK KDEILELYLNKSFFGNRAYGIAAAAEFYYGKKLNELNLDEMASLAGIPKFPSSGNPITNPARARERRDLYVLQRMVDLNF ITQDQANAAKAIPMHAKPHEPPVQVYAPYAAEMVRQEMIAKYGGAALNKGYHVTTTIDGTLQMAAETSVRNGLALYEHRH RWRGAEQHIEVDANADTATLAAHLSGISSQGGMFPVIVARTTPEGSAIVVRSDRSELTLPPAASRWTGTPLNKLLKRGDV VRVRPGEKRGEWTLEQLPSAQSTLVSLDANNGALRALVGGFSFTANKFNRATQARRQPGSSFKPFVYSAALEKGFNPASI VPDAPVIFRDRRGHTWSPQNDDGKFQGPMRIRDALVQSRNLVSVRLLDAIGIDFARNYITQFGFEENEIPPNLSMSLGTA SLTPLSIARGYAVFANGGFRIDPWLIDEIHDREHKLIFKNNPKVACSSCTSANTNVTQSTSHLVDGFNFGAPTKTEPSKP VKNNNEPTQTIPSPDPNTPMAPRAIDERVVFQLVSMMRDVVLRGTATAARSLNRQDIAGKTGSTNEHRDAWFSGFGGPYV TTVWVGRDDFQSLGYREYGGKAALPIWIEYMRTALKDKPIARNAPPQGMTQTTLNGATEWVKNEDINHLQDHDFKLHEEE SDEQTFDIF >Mature_809_residues MYRLRGWLGWLLTILIILTLVGILAAGSMYYAISSKLPDIRNLKQVELQEPMYVYSHDGLLIAIFGEIRRYPVQIKEVPE QLKQAFLATEDARFYEHSGIDYKGIARAIWLLATTNEKRVPGGSTITQQVARQFFLNSEYSYKRKLAEILLARKIESQLK KDEILELYLNKSFFGNRAYGIAAAAEFYYGKKLNELNLDEMASLAGIPKFPSSGNPITNPARARERRDLYVLQRMVDLNF ITQDQANAAKAIPMHAKPHEPPVQVYAPYAAEMVRQEMIAKYGGAALNKGYHVTTTIDGTLQMAAETSVRNGLALYEHRH RWRGAEQHIEVDANADTATLAAHLSGISSQGGMFPVIVARTTPEGSAIVVRSDRSELTLPPAASRWTGTPLNKLLKRGDV VRVRPGEKRGEWTLEQLPSAQSTLVSLDANNGALRALVGGFSFTANKFNRATQARRQPGSSFKPFVYSAALEKGFNPASI VPDAPVIFRDRRGHTWSPQNDDGKFQGPMRIRDALVQSRNLVSVRLLDAIGIDFARNYITQFGFEENEIPPNLSMSLGTA SLTPLSIARGYAVFANGGFRIDPWLIDEIHDREHKLIFKNNPKVACSSCTSANTNVTQSTSHLVDGFNFGAPTKTEPSKP VKNNNEPTQTIPSPDPNTPMAPRAIDERVVFQLVSMMRDVVLRGTATAARSLNRQDIAGKTGSTNEHRDAWFSGFGGPYV TTVWVGRDDFQSLGYREYGGKAALPIWIEYMRTALKDKPIARNAPPQGMTQTTLNGATEWVKNEDINHLQDHDFKLHEEE SDEQTFDIF
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=816, Percent_Identity=39.093137254902, Blast_Score=553, Evalue=1e-158, Organism=Escherichia coli, GI1786343, Length=260, Percent_Identity=36.1538461538462, Blast_Score=129, Evalue=8e-31, Organism=Escherichia coli, GI1788867, Length=268, Percent_Identity=32.089552238806, Blast_Score=118, Evalue=2e-27, Organism=Escherichia coli, GI1789601, Length=178, Percent_Identity=33.1460674157303, Blast_Score=88, Evalue=2e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 90179; Mature: 90179
Theoretical pI: Translated: 9.35; Mature: 9.35
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYRLRGWLGWLLTILIILTLVGILAAGSMYYAISSKLPDIRNLKQVELQEPMYVYSHDGL CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHCCCCCHHCCHHHHHCCCEEEEECCCE LIAIFGEIRRYPVQIKEVPEQLKQAFLATEDARFYEHSGIDYKGIARAIWLLATTNEKRV EEEEEHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHEEEEEEECCCCCC PGGSTITQQVARQFFLNSEYSYKRKLAEILLARKIESQLKKDEILELYLNKSFFGNRAYG CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH IAAAAEFYYGKKLNELNLDEMASLAGIPKFPSSGNPITNPARARERRDLYVLQRMVDLNF HHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCE ITQDQANAAKAIPMHAKPHEPPVQVYAPYAAEMVRQEMIAKYGGAALNKGYHVTTTIDGT EECCCCCCHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCH LQMAAETSVRNGLALYEHRHRWRGAEQHIEVDANADTATLAAHLSGISSQGGMFPVIVAR HHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEEE TTPEGSAIVVRSDRSELTLPPAASRWTGTPLNKLLKRGDVVRVRPGEKRGEWTLEQLPSA ECCCCCEEEEECCCCCEECCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCHHHHCCCC QSTLVSLDANNGALRALVGGFSFTANKFNRATQARRQPGSSFKPFVYSAALEKGFNPASI CCEEEEEECCCCEEEHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCC VPDAPVIFRDRRGHTWSPQNDDGKFQGPMRIRDALVQSRNLVSVRLLDAIGIDFARNYIT CCCCCEEEECCCCCCCCCCCCCCCEECHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH QFGFEENEIPPNLSMSLGTASLTPLSIARGYAVFANGGFRIDPWLIDEIHDREHKLIFKN HCCCCCCCCCCCCEEECCCCCCCHHHHHCCEEEEECCCEEECCCHHHHHCCCCCEEEEEC NPKVACSSCTSANTNVTQSTSHLVDGFNFGAPTKTEPSKPVKNNNEPTQTIPSPDPNTPM CCCEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC APRAIDERVVFQLVSMMRDVVLRGTATAARSLNRQDIAGKTGSTNEHRDAWFSGFGGPYV CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHCCCCCCCCCCHHHHHHCCCCCCEE TTVWVGRDDFQSLGYREYGGKAALPIWIEYMRTALKDKPIARNAPPQGMTQTTLNGATEW EEEEECCHHHHHCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH VKNEDINHLQDHDFKLHEEESDEQTFDIF HCCCCCCHHCCCCCEECCCCCCCCEECCC >Mature Secondary Structure MYRLRGWLGWLLTILIILTLVGILAAGSMYYAISSKLPDIRNLKQVELQEPMYVYSHDGL CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHCCCCCHHCCHHHHHCCCEEEEECCCE LIAIFGEIRRYPVQIKEVPEQLKQAFLATEDARFYEHSGIDYKGIARAIWLLATTNEKRV EEEEEHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHEEEEEEECCCCCC PGGSTITQQVARQFFLNSEYSYKRKLAEILLARKIESQLKKDEILELYLNKSFFGNRAYG CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH IAAAAEFYYGKKLNELNLDEMASLAGIPKFPSSGNPITNPARARERRDLYVLQRMVDLNF HHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCE ITQDQANAAKAIPMHAKPHEPPVQVYAPYAAEMVRQEMIAKYGGAALNKGYHVTTTIDGT EECCCCCCHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCH LQMAAETSVRNGLALYEHRHRWRGAEQHIEVDANADTATLAAHLSGISSQGGMFPVIVAR HHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEEE TTPEGSAIVVRSDRSELTLPPAASRWTGTPLNKLLKRGDVVRVRPGEKRGEWTLEQLPSA ECCCCCEEEEECCCCCEECCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCHHHHCCCC QSTLVSLDANNGALRALVGGFSFTANKFNRATQARRQPGSSFKPFVYSAALEKGFNPASI CCEEEEEECCCCEEEHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCC VPDAPVIFRDRRGHTWSPQNDDGKFQGPMRIRDALVQSRNLVSVRLLDAIGIDFARNYIT CCCCCEEEECCCCCCCCCCCCCCCEECHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH QFGFEENEIPPNLSMSLGTASLTPLSIARGYAVFANGGFRIDPWLIDEIHDREHKLIFKN HCCCCCCCCCCCCEEECCCCCCCHHHHHCCEEEEECCCEEECCCHHHHHCCCCCEEEEEC NPKVACSSCTSANTNVTQSTSHLVDGFNFGAPTKTEPSKPVKNNNEPTQTIPSPDPNTPM CCCEEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC APRAIDERVVFQLVSMMRDVVLRGTATAARSLNRQDIAGKTGSTNEHRDAWFSGFGGPYV CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHCCCCCCCCCCHHHHHHCCCCCCEE TTVWVGRDDFQSLGYREYGGKAALPIWIEYMRTALKDKPIARNAPPQGMTQTTLNGATEW EEEEECCHHHHHCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH VKNEDINHLQDHDFKLHEEESDEQTFDIF HCCCCCCHHCCCCCEECCCCCCCCEECCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10910347 [H]