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The map label for this gene is rbsK [H]

Identifier: 182682309

GI number: 182682309

Start: 1991646

End: 1992599

Strand: Direct

Name: rbsK [H]

Synonym: XfasM23_1792

Alternate gene names: 182682309

Gene position: 1991646-1992599 (Clockwise)

Preceding gene: 182682307

Following gene: 182682318

Centisome position: 78.54

GC content: 56.29

Gene sequence:

>954_bases
ATGCATTCAGTCGTCGTCGTCGGCTCCTTCAGTATTGATCATGTTTGGCGCTGCGACACATTGCCCACACCTGGTGCAAC
AATTGCCGGCCGCTATAGCCGTGGTCCAGGAGGCAAAGGCTTCAACCAAGCCGTGGCGGCTTGCCGCGCTGGTGCGCGCA
CCTATTTCATATGCGCACTCGGCAATGACACCGACGGCAATATGGCACGCGACATCGCCACAAAAGACGGCTTCACACTG
ATCGGCGAATCCAGCACCGAACCCACTGGCACCGGAGGGATCTATGTCGACAGCCACGGCCATAACACTATCGTCACTGG
CGCTGGTGCCAACGCAGTACTGAGCACCCACTTCATCACAGAACAACGCGCCCTAATTACCTCAGCATGGATCGTCTTGG
CACAACTGGAATCACCGATAGAAACACTCGAAACGGCGCTCAGCATGGCGCGCGAAGCTGGCCGCTTGACCATACTCAAT
GCTGCCCCCGCCAATGCAACCGCCACGATCAACCTACTCAAATTGGCCGACGTGCTCACACTGAACGAAACGGAATTCGT
CGCCTTGCTCAGCCGTCACGTCGGTGAAAGGATCAGTCCCGACAACGTCGCCACCACCGATGGCAACACACTACACGCCT
TATGCAACAAACTACTGTCCGGCAGTACGGTTGTCATTACATTAGGCTCGGCTGGCGTATTCGTTTCACACTCGGAAGAA
AACCTGCGTGGTGACACCCAGCCCTACTATCGTGTGGCCGCCGAACAGGCCCACACCGTAGACACCACCGGAGCTGGCGA
CGCATTTAATGGTGCTTTGGCAGCATCCCTGGCACGGCAACCAAACACAGCGTTTATCCAGCACATACGCCTCGCCAATA
GCTATGCAGCGCGCTCGACCGAAACAGAAGGTGGAGCCGTATCAATGCCAATATTAACGACTACCCAAGACTAA

Upstream 100 bases:

>100_bases
GTATTAGGCTCAATGTCTCGATCATCACCATCATGACAGCTAACATGGACAATACGTTGTCGCACCTTGTCTAACTCACA
CTCCATATTTAAAGGTTCTT

Downstream 100 bases:

>100_bases
ACAGGCACGAAATAAAGTAGAGAGTGCAATGACTCACCACCCCGGCGAGCGCATCTGACTGCCCACTCATCCTGAGCACA
AAAAGTCATCAGCTGTATGA

Product: ribokinase-like domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MHSVVVVGSFSIDHVWRCDTLPTPGATIAGRYSRGPGGKGFNQAVAACRAGARTYFICALGNDTDGNMARDIATKDGFTL
IGESSTEPTGTGGIYVDSHGHNTIVTGAGANAVLSTHFITEQRALITSAWIVLAQLESPIETLETALSMAREAGRLTILN
AAPANATATINLLKLADVLTLNETEFVALLSRHVGERISPDNVATTDGNTLHALCNKLLSGSTVVITLGSAGVFVSHSEE
NLRGDTQPYYRVAAEQAHTVDTTGAGDAFNGALAASLARQPNTAFIQHIRLANSYAARSTETEGGAVSMPILTTTQD

Sequences:

>Translated_317_residues
MHSVVVVGSFSIDHVWRCDTLPTPGATIAGRYSRGPGGKGFNQAVAACRAGARTYFICALGNDTDGNMARDIATKDGFTL
IGESSTEPTGTGGIYVDSHGHNTIVTGAGANAVLSTHFITEQRALITSAWIVLAQLESPIETLETALSMAREAGRLTILN
AAPANATATINLLKLADVLTLNETEFVALLSRHVGERISPDNVATTDGNTLHALCNKLLSGSTVVITLGSAGVFVSHSEE
NLRGDTQPYYRVAAEQAHTVDTTGAGDAFNGALAASLARQPNTAFIQHIRLANSYAARSTETEGGAVSMPILTTTQD
>Mature_317_residues
MHSVVVVGSFSIDHVWRCDTLPTPGATIAGRYSRGPGGKGFNQAVAACRAGARTYFICALGNDTDGNMARDIATKDGFTL
IGESSTEPTGTGGIYVDSHGHNTIVTGAGANAVLSTHFITEQRALITSAWIVLAQLESPIETLETALSMAREAGRLTILN
AAPANATATINLLKLADVLTLNETEFVALLSRHVGERISPDNVATTDGNTLHALCNKLLSGSTVVITLGSAGVFVSHSEE
NLRGDTQPYYRVAAEQAHTVDTTGAGDAFNGALAASLARQPNTAFIQHIRLANSYAARSTETEGGAVSMPILTTTQD

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=311, Percent_Identity=36.6559485530547, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1790193, Length=281, Percent_Identity=39.8576512455516, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI87082343, Length=322, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=307, Percent_Identity=31.2703583061889, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI20128807, Length=314, Percent_Identity=36.9426751592357, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24583886, Length=311, Percent_Identity=31.1897106109325, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33096; Mature: 33096

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSVVVVGSFSIDHVWRCDTLPTPGATIAGRYSRGPGGKGFNQAVAACRAGARTYFICAL
CCEEEEEECCCCCCEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
GNDTDGNMARDIATKDGFTLIGESSTEPTGTGGIYVDSHGHNTIVTGAGANAVLSTHFIT
CCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCEEEECCCCCEEEECCCCCCEEEEHHHH
EQRALITSAWIVLAQLESPIETLETALSMAREAGRLTILNAAPANATATINLLKLADVLT
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEHEEHHHHEE
LNETEFVALLSRHVGERISPDNVATTDGNTLHALCNKLLSGSTVVITLGSAGVFVSHSEE
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEECCHH
NLRGDTQPYYRVAAEQAHTVDTTGAGDAFNGALAASLARQPNTAFIQHIRLANSYAARST
HCCCCCCHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
ETEGGAVSMPILTTTQD
CCCCCEEEEEEEEECCC
>Mature Secondary Structure
MHSVVVVGSFSIDHVWRCDTLPTPGATIAGRYSRGPGGKGFNQAVAACRAGARTYFICAL
CCEEEEEECCCCCCEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
GNDTDGNMARDIATKDGFTLIGESSTEPTGTGGIYVDSHGHNTIVTGAGANAVLSTHFIT
CCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCEEEECCCCCEEEECCCCCCEEEEHHHH
EQRALITSAWIVLAQLESPIETLETALSMAREAGRLTILNAAPANATATINLLKLADVLT
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEHEEHHHHEE
LNETEFVALLSRHVGERISPDNVATTDGNTLHALCNKLLSGSTVVITLGSAGVFVSHSEE
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEECCHH
NLRGDTQPYYRVAAEQAHTVDTTGAGDAFNGALAASLARQPNTAFIQHIRLANSYAARST
HCCCCCCHHHHHHHHHCCEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
ETEGGAVSMPILTTTQD
CCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]