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The map label for this gene is fabF [H]

Identifier: 182682108

GI number: 182682108

Start: 1757674

End: 1758909

Strand: Reverse

Name: fabF [H]

Synonym: XfasM23_1586

Alternate gene names: 182682108

Gene position: 1758909-1757674 (Counterclockwise)

Preceding gene: 182682109

Following gene: 182682107

Centisome position: 69.37

GC content: 52.02

Gene sequence:

>1236_bases
ATGAATCGTCGGGTTGTCGTTACTGGGATGGGGATGGTGTCGCCGTTGGGCAATGATTTGACCACAAGTTGGGATGGCAT
CGTTCACGGACGTTCGGGTATCGCTCCCATCGTCCAGATTGATGCTTCTAAGTTCCCCACTCAGATTGCTGGCGAAATCA
AGGGATTCGATCCAACGAAGTTCGTATCCGCGAAGGATGCGAAGAAAATGGATTCGTTCATTTACTATGGTATAGGCGCA
GCGTTTATGGCGCTGGATGATGCTGGTTTAGAGATCAATGAGATCAATGCTGAGCGTGTTGGTGCCCTGATCGGTTCTGG
TATAGGTGGCGTGTTTGGCATTGAAGAGCAAACCATCAAGCTCTATGAGGGGGGCGCACGCAAGATATCTCCTTTCTATG
TGCCAGCGACGATCATCAACATGCTGCCAGGACAGTTGAGTGTTTTGAAAGGCTTGAAAGGCCCGACGTTCTCTGCGGTA
TCTGCCTGCGCGACTTCAAACCACTCCATTGGTATGGCAATGCGCATGATCCAGTATGGTGATGCTGATGTTATGTTGGC
TGGTGGTTCTGAGCGCGCTTCTTCGCCAACTGCGATTGGTGGCTTTTGTGCGATGAGGGCGATGTCTACGCGTAACGATG
ATCCAACCGGCGCTTCGCGGCCGTGGGACAAGGGGCGCGATGGCTTTGTGCTTGGTGATGGTGCCGGCATTCTAGTGCTG
GAAGAGTATGAGTATGCTAAAGCGCGAGGCGCACGCATCTATGCTGAATTGGCTGGTTTCGGCGCCACTTCCGATGCCTT
CCACATGACGATGCCAGTCGAGGATGGTGAAGGTGCAGCGCGTTGTATGCGTATAGCGTTGCAGGATGCGAGGGTCACTC
CGGAGCAAATTGATTATCTCAATGCACACGGTACCTCAACTCCTTTGGGCGATCTGTGCGAAACCAACGCGATCAAGACG
GTATTAGGAGGTCATGCCTACAAAGTGATGGTTAGCTCGACCAAATCAATGACCGGACATCTACTCGGTGCGGCCGGTGG
TGTGGAAGCAATTTTCTCAGTGATGGCGTTGCATACTGGCATCGTTCCGCCGACGATTAATCTCGAAGAACCAGACGAAG
GCTGTGATCTTGATTACGTGCCGCATGTGGCGCGTGAGGCCAAACTGGATGTGGTGATTTCAAACGGTTTTGGTTTTGGT
GGTACTAACGGCACATTAGTGTTCAAGCGTATATGA

Upstream 100 bases:

>100_bases
CGCTGCTGCGGCCCTGTTTTTATTACAACGCTTGTAAATAAGTAAGAATGAAGTTTGTAATCGTTCCAAATAGTAAGAAT
CCTTGGTCAGGAGATCTGTA

Downstream 100 bases:

>100_bases
TGGTTTCCTGTTTGCCTTGACACGTTTGAGAGGGGCGCATGGTTGAGCGATGCGCCCTTTATACTGTGTAAAAATGTGTT
TTATCCATCGCTGTTTTGGT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNRRVVVTGMGMVSPLGNDLTTSWDGIVHGRSGIAPIVQIDASKFPTQIAGEIKGFDPTKFVSAKDAKKMDSFIYYGIGA
AFMALDDAGLEINEINAERVGALIGSGIGGVFGIEEQTIKLYEGGARKISPFYVPATIINMLPGQLSVLKGLKGPTFSAV
SACATSNHSIGMAMRMIQYGDADVMLAGGSERASSPTAIGGFCAMRAMSTRNDDPTGASRPWDKGRDGFVLGDGAGILVL
EEYEYAKARGARIYAELAGFGATSDAFHMTMPVEDGEGAARCMRIALQDARVTPEQIDYLNAHGTSTPLGDLCETNAIKT
VLGGHAYKVMVSSTKSMTGHLLGAAGGVEAIFSVMALHTGIVPPTINLEEPDEGCDLDYVPHVAREAKLDVVISNGFGFG
GTNGTLVFKRI

Sequences:

>Translated_411_residues
MNRRVVVTGMGMVSPLGNDLTTSWDGIVHGRSGIAPIVQIDASKFPTQIAGEIKGFDPTKFVSAKDAKKMDSFIYYGIGA
AFMALDDAGLEINEINAERVGALIGSGIGGVFGIEEQTIKLYEGGARKISPFYVPATIINMLPGQLSVLKGLKGPTFSAV
SACATSNHSIGMAMRMIQYGDADVMLAGGSERASSPTAIGGFCAMRAMSTRNDDPTGASRPWDKGRDGFVLGDGAGILVL
EEYEYAKARGARIYAELAGFGATSDAFHMTMPVEDGEGAARCMRIALQDARVTPEQIDYLNAHGTSTPLGDLCETNAIKT
VLGGHAYKVMVSSTKSMTGHLLGAAGGVEAIFSVMALHTGIVPPTINLEEPDEGCDLDYVPHVAREAKLDVVISNGFGFG
GTNGTLVFKRI
>Mature_411_residues
MNRRVVVTGMGMVSPLGNDLTTSWDGIVHGRSGIAPIVQIDASKFPTQIAGEIKGFDPTKFVSAKDAKKMDSFIYYGIGA
AFMALDDAGLEINEINAERVGALIGSGIGGVFGIEEQTIKLYEGGARKISPFYVPATIINMLPGQLSVLKGLKGPTFSAV
SACATSNHSIGMAMRMIQYGDADVMLAGGSERASSPTAIGGFCAMRAMSTRNDDPTGASRPWDKGRDGFVLGDGAGILVL
EEYEYAKARGARIYAELAGFGATSDAFHMTMPVEDGEGAARCMRIALQDARVTPEQIDYLNAHGTSTPLGDLCETNAIKT
VLGGHAYKVMVSSTKSMTGHLLGAAGGVEAIFSVMALHTGIVPPTINLEEPDEGCDLDYVPHVAREAKLDVVISNGFGFG
GTNGTLVFKRI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=417, Percent_Identity=46.0431654676259, Blast_Score=360, Evalue=1e-99,
Organism=Homo sapiens, GI223972627, Length=151, Percent_Identity=54.3046357615894, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI41872631, Length=435, Percent_Identity=23.448275862069, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI1787337, Length=411, Percent_Identity=59.6107055961071, Blast_Score=473, Evalue=1e-135,
Organism=Escherichia coli, GI1788663, Length=416, Percent_Identity=41.5865384615385, Blast_Score=263, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71983541, Length=413, Percent_Identity=37.5302663438257, Blast_Score=250, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71983535, Length=265, Percent_Identity=42.6415094339623, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI212642053, Length=373, Percent_Identity=24.3967828418231, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=366, Percent_Identity=27.0491803278689, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=37.1364653243848, Blast_Score=284, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24644341, Length=418, Percent_Identity=43.5406698564593, Blast_Score=324, Evalue=7e-89,
Organism=Drosophila melanogaster, GI19920632, Length=368, Percent_Identity=24.7282608695652, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221330659, Length=369, Percent_Identity=24.6612466124661, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24581345, Length=376, Percent_Identity=24.7340425531915, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43203; Mature: 43203

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRVVVTGMGMVSPLGNDLTTSWDGIVHGRSGIAPIVQIDASKFPTQIAGEIKGFDPTK
CCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCHHHHHCCCCCCCHH
FVSAKDAKKMDSFIYYGIGAAFMALDDAGLEINEINAERVGALIGSGIGGVFGIEEQTIK
CCCCHHHHHHHHEEEEHHCEEEEEECCCCCEEEECCHHHHHHHHHCCCCCEECCCCCEEE
LYEGGARKISPFYVPATIINMLPGQLSVLKGLKGPTFSAVSACATSNHSIGMAMRMIQYG
EECCCCCCCCCEEHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCC
DADVMLAGGSERASSPTAIGGFCAMRAMSTRNDDPTGASRPWDKGRDGFVLGDGAGILVL
CCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
EEYEYAKARGARIYAELAGFGATSDAFHMTMPVEDGEGAARCMRIALQDARVTPEQIDYL
ECCCHHHHCCCEEEEEHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHEE
NAHGTSTPLGDLCETNAIKTVLGGHAYKVMVSSTKSMTGHLLGAAGGVEAIFSVMALHTG
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHEEECCCCHHHHHHHHHHHHC
IVPPTINLEEPDEGCDLDYVPHVAREAKLDVVISNGFGFGGTNGTLVFKRI
CCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MNRRVVVTGMGMVSPLGNDLTTSWDGIVHGRSGIAPIVQIDASKFPTQIAGEIKGFDPTK
CCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCHHHHHCCCCCCCHH
FVSAKDAKKMDSFIYYGIGAAFMALDDAGLEINEINAERVGALIGSGIGGVFGIEEQTIK
CCCCHHHHHHHHEEEEHHCEEEEEECCCCCEEEECCHHHHHHHHHCCCCCEECCCCCEEE
LYEGGARKISPFYVPATIINMLPGQLSVLKGLKGPTFSAVSACATSNHSIGMAMRMIQYG
EECCCCCCCCCEEHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCC
DADVMLAGGSERASSPTAIGGFCAMRAMSTRNDDPTGASRPWDKGRDGFVLGDGAGILVL
CCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
EEYEYAKARGARIYAELAGFGATSDAFHMTMPVEDGEGAARCMRIALQDARVTPEQIDYL
ECCCHHHHCCCEEEEEHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHEE
NAHGTSTPLGDLCETNAIKTVLGGHAYKVMVSSTKSMTGHLLGAAGGVEAIFSVMALHTG
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHEEECCCCHHHHHHHHHHHHC
IVPPTINLEEPDEGCDLDYVPHVAREAKLDVVISNGFGFGGTNGTLVFKRI
CCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]