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The map label for this gene is degQ [C]

Identifier: 182681903

GI number: 182681903

Start: 1517603

End: 1519147

Strand: Direct

Name: degQ [C]

Synonym: XfasM23_1371

Alternate gene names: 182681903

Gene position: 1517603-1519147 (Clockwise)

Preceding gene: 182681902

Following gene: 182681904

Centisome position: 59.85

GC content: 53.66

Gene sequence:

>1545_bases
ATGAATTCACGTATCCATACACGATGCTTCGGCCTACTCGCCATCACCTTGCCGTTAGCTGCCTGTGGCGCGCAACACAA
CAACAGCCCCACTCCCACTGCACACTCCACCCCCATTGTGACCCCCAGCACCACCCCAGCACCACAGCTCGTGGCTGGGT
TGCCAGATTTCACCCAACTGGTCGACCAAGTAGGGCCTGGTGTGGTCAACATTGAAACCGTCATTACCCGTAAGAAAGTC
GGCAAACGTCGCGGTATACCGCTTGACAACGATATACCCGAGTTTTTCCGGCGTTTCTTTGGCCCAGATTTCCAGATGCC
GAACCAACCTCGTGGCGGCCAGGATGACGAGGGAGGTATCGCTGGTCGGGGAATGGGCTCTGGCTTCATCATTTCCAAAG
ACGGCTACATACTCACCAACCATCACGTCATCACTGGCGCAAGCGAGGTCACAATCAAATTGACTGATCGCCGCGAATTC
AAAGCAAAAGTCATCGGTAGCGACGAACAGTACGATGTTGCTTTACTCAAAATAGATGCAAAAAATCTACCCACCGTGCG
TATCGGCGACTCCAGTTCACTTAAACCTGGTCAGTGGGTCGTTGCGATCGGCTCCCCCTTCGGATTAGATCACTCAGTCA
CTGCAGGGATAGTCAGCGCACTGGGACGCAGCACCAGTGACGATCAACGCTATGTCCCATTTATCCAAACCGACGTACCC
ATTAACCAGGGAAATTCTGGTGGTCCATTGCTGAATACCCGAGGTGAAGTGATTGGTATCAACTCGCAAATATTTTCCGC
CTCAGGCGGCTACATGGGTATTAGCTTTGCCATTCCAATCAATTTGGCAATCAACGCTGCCGAACAAATCCGTAAAACAG
GCAAAGTGCAACGCAGTATGCTCGGTGTTGAAATCGGCCCTATCGACGCACTCAAAGCTCAAGGCCTAGGCTTACCGGAC
AGCCGAGGCGCACTGGTCAATAACATTCCACCCCACAGCCCGGCCGCCAAAGCAGGGATTGAAGTCGGTGACGTCATCCG
CTCAGTGAACGGCAAAGTAATCAGTAGCTTCAGCGATCTGCCTCCACTGATCGGCATGATGCCGCCAGGCACCAAAGCCA
CCCTGGGTATTATCCGTGACGGCAAATCGCTTGAGATCGTCGTCACTCTTTCGGCACTCAATCAGGATGCAACAGTCAGC
GAAGATGAAGACGACACATCACCTTCCAAACCAGAAACCTCTGCCAATGTCGAACTGCTCGGCCTTCAAGTCGAAAACCT
GAGCGCTGCTGAGCGCGAACGCCTGGCCTCATCGCAAAACGCGAAGGGAGGAGTCCGTATCACGGCAGTCACAGCGCCGT
GGGCACGCAACGCCAACCCGCCATTAGTGGAAGGTTTATTTATCCTAAGGATCGGCCGCACTCCGGTTAGCAATGTGGCA
GAACTGAACCGTGCCCTAGGAAATTATAAGAAGGGAGATGTCATCATGCTCCTGGTGACCAACGGCCGTGGCACGTTCTA
CAGTGCGTTGAAAGCAGGCGGCTAA

Upstream 100 bases:

>100_bases
TAAGACCACCTCCTCACGGACTTCACGATGTCCCTTACCACTCACCGGTGTCGTTACCCCGGTTTGACTCACTTTGTTTC
GCAATCAGGAGATTGATCTG

Downstream 100 bases:

>100_bases
GCAGTCACACACCAGACAACACACACTGCATCCACCAATGCGTCTGGGCGTCCCGTCATTCCTCGTCGGCAACGGGACAC
CCAGACCGAACTTCATCAAT

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MNSRIHTRCFGLLAITLPLAACGAQHNNSPTPTAHSTPIVTPSTTPAPQLVAGLPDFTQLVDQVGPGVVNIETVITRKKV
GKRRGIPLDNDIPEFFRRFFGPDFQMPNQPRGGQDDEGGIAGRGMGSGFIISKDGYILTNHHVITGASEVTIKLTDRREF
KAKVIGSDEQYDVALLKIDAKNLPTVRIGDSSSLKPGQWVVAIGSPFGLDHSVTAGIVSALGRSTSDDQRYVPFIQTDVP
INQGNSGGPLLNTRGEVIGINSQIFSASGGYMGISFAIPINLAINAAEQIRKTGKVQRSMLGVEIGPIDALKAQGLGLPD
SRGALVNNIPPHSPAAKAGIEVGDVIRSVNGKVISSFSDLPPLIGMMPPGTKATLGIIRDGKSLEIVVTLSALNQDATVS
EDEDDTSPSKPETSANVELLGLQVENLSAAERERLASSQNAKGGVRITAVTAPWARNANPPLVEGLFILRIGRTPVSNVA
ELNRALGNYKKGDVIMLLVTNGRGTFYSALKAGG

Sequences:

>Translated_514_residues
MNSRIHTRCFGLLAITLPLAACGAQHNNSPTPTAHSTPIVTPSTTPAPQLVAGLPDFTQLVDQVGPGVVNIETVITRKKV
GKRRGIPLDNDIPEFFRRFFGPDFQMPNQPRGGQDDEGGIAGRGMGSGFIISKDGYILTNHHVITGASEVTIKLTDRREF
KAKVIGSDEQYDVALLKIDAKNLPTVRIGDSSSLKPGQWVVAIGSPFGLDHSVTAGIVSALGRSTSDDQRYVPFIQTDVP
INQGNSGGPLLNTRGEVIGINSQIFSASGGYMGISFAIPINLAINAAEQIRKTGKVQRSMLGVEIGPIDALKAQGLGLPD
SRGALVNNIPPHSPAAKAGIEVGDVIRSVNGKVISSFSDLPPLIGMMPPGTKATLGIIRDGKSLEIVVTLSALNQDATVS
EDEDDTSPSKPETSANVELLGLQVENLSAAERERLASSQNAKGGVRITAVTAPWARNANPPLVEGLFILRIGRTPVSNVA
ELNRALGNYKKGDVIMLLVTNGRGTFYSALKAGG
>Mature_514_residues
MNSRIHTRCFGLLAITLPLAACGAQHNNSPTPTAHSTPIVTPSTTPAPQLVAGLPDFTQLVDQVGPGVVNIETVITRKKV
GKRRGIPLDNDIPEFFRRFFGPDFQMPNQPRGGQDDEGGIAGRGMGSGFIISKDGYILTNHHVITGASEVTIKLTDRREF
KAKVIGSDEQYDVALLKIDAKNLPTVRIGDSSSLKPGQWVVAIGSPFGLDHSVTAGIVSALGRSTSDDQRYVPFIQTDVP
INQGNSGGPLLNTRGEVIGINSQIFSASGGYMGISFAIPINLAINAAEQIRKTGKVQRSMLGVEIGPIDALKAQGLGLPD
SRGALVNNIPPHSPAAKAGIEVGDVIRSVNGKVISSFSDLPPLIGMMPPGTKATLGIIRDGKSLEIVVTLSALNQDATVS
EDEDDTSPSKPETSANVELLGLQVENLSAAERERLASSQNAKGGVRITAVTAPWARNANPPLVEGLFILRIGRTPVSNVA
ELNRALGNYKKGDVIMLLVTNGRGTFYSALKAGG

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=258, Percent_Identity=40.6976744186046, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI22129776, Length=253, Percent_Identity=38.7351778656126, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI24308541, Length=254, Percent_Identity=36.6141732283465, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI7019477, Length=251, Percent_Identity=36.6533864541833, Blast_Score=132, Evalue=7e-31,
Organism=Escherichia coli, GI1789629, Length=339, Percent_Identity=45.1327433628319, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI1786356, Length=486, Percent_Identity=36.6255144032922, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1789630, Length=272, Percent_Identity=40.0735294117647, Blast_Score=176, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24646839, Length=285, Percent_Identity=35.4385964912281, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 54189; Mature: 54189

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSRIHTRCFGLLAITLPLAACGAQHNNSPTPTAHSTPIVTPSTTPAPQLVAGLPDFTQL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCHHHHHCCCHHHHH
VDQVGPGVVNIETVITRKKVGKRRGIPLDNDIPEFFRRFFGPDFQMPNQPRGGQDDEGGI
HHHHCCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
AGRGMGSGFIISKDGYILTNHHVITGASEVTIKLTDRREFKAKVIGSDEQYDVALLKIDA
ECCCCCCCEEEECCCEEEECCEEEECCCEEEEEEECCCCEEEEEECCCCCEEEEEEEEEC
KNLPTVRIGDSSSLKPGQWVVAIGSPFGLDHSVTAGIVSALGRSTSDDQRYVPFIQTDVP
CCCCEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEECCEEEECCC
INQGNSGGPLLNTRGEVIGINSQIFSASGGYMGISFAIPINLAINAAEQIRKTGKVQRSM
CCCCCCCCCEECCCCCEEEECCEEEECCCCEEEEEEEEEEEEEECCHHHHHHHHHHHHHH
LGVEIGPIDALKAQGLGLPDSRGALVNNIPPHSPAAKAGIEVGDVIRSVNGKVISSFSDL
HCEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCEEHHHHCC
PPLIGMMPPGTKATLGIIRDGKSLEIVVTLSALNQDATVSEDEDDTSPSKPETSANVELL
CHHHCCCCCCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
GLQVENLSAAERERLASSQNAKGGVRITAVTAPWARNANPPLVEGLFILRIGRTPVSNVA
EEEECCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHCCEEEEEECCCCHHHHH
ELNRALGNYKKGDVIMLLVTNGRGTFYSALKAGG
HHHHHHCCCCCCCEEEEEEECCCCHHHHHHHCCC
>Mature Secondary Structure
MNSRIHTRCFGLLAITLPLAACGAQHNNSPTPTAHSTPIVTPSTTPAPQLVAGLPDFTQL
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCHHHHHCCCHHHHH
VDQVGPGVVNIETVITRKKVGKRRGIPLDNDIPEFFRRFFGPDFQMPNQPRGGQDDEGGI
HHHHCCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
AGRGMGSGFIISKDGYILTNHHVITGASEVTIKLTDRREFKAKVIGSDEQYDVALLKIDA
ECCCCCCCEEEECCCEEEECCEEEECCCEEEEEEECCCCEEEEEECCCCCEEEEEEEEEC
KNLPTVRIGDSSSLKPGQWVVAIGSPFGLDHSVTAGIVSALGRSTSDDQRYVPFIQTDVP
CCCCEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEECCEEEECCC
INQGNSGGPLLNTRGEVIGINSQIFSASGGYMGISFAIPINLAINAAEQIRKTGKVQRSM
CCCCCCCCCEECCCCCEEEECCEEEECCCCEEEEEEEEEEEEEECCHHHHHHHHHHHHHH
LGVEIGPIDALKAQGLGLPDSRGALVNNIPPHSPAAKAGIEVGDVIRSVNGKVISSFSDL
HCEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCEEHHHHCC
PPLIGMMPPGTKATLGIIRDGKSLEIVVTLSALNQDATVSEDEDDTSPSKPETSANVELL
CHHHCCCCCCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
GLQVENLSAAERERLASSQNAKGGVRITAVTAPWARNANPPLVEGLFILRIGRTPVSNVA
EEEECCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHCCEEEEEECCCCHHHHH
ELNRALGNYKKGDVIMLLVTNGRGTFYSALKAGG
HHHHHHCCCCCCCEEEEEEECCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]