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The map label for this gene is ruvB

Identifier: 182681490

GI number: 182681490

Start: 1109983

End: 1111014

Strand: Direct

Name: ruvB

Synonym: XfasM23_0944

Alternate gene names: 182681490

Gene position: 1109983-1111014 (Clockwise)

Preceding gene: 182681489

Following gene: 182681491

Centisome position: 43.77

GC content: 52.23

Gene sequence:

>1032_bases
ATGGATCGCATCATCGACAGCGCAGCCACCCGTGAGGATGAAGCGATTGAGGTCAGTATTCGTCCCAAGCGTTTGGCTGA
TTATCTCGGTCAACAACCTGTACGTGAGCAGATGGATATCTACATCCAAGCCACTAAGGCGCGTGCTGAGGCATTGGATC
ACGTACTCATTTTTGGTCCACCTGGATTGGGCAAGACCACCTTGAGCCATGTCATTGCTTACGAACTCGGGGTCAAGCTA
CGTGTGACTTCTGGTCCAGTGATCGAGAAAGCAGGAGATCTGGCCGCACTGCTTACCAATCTACAGCCTTACGATGTGCT
GTTTATTGATGAGATTCATCGGCTATCACCAGTGGTTGAGGAGGTGTTATATCCAGCAATGGAGGACTTCCAGATCGATA
TTATGATTGGCGAGGGGCCGGCTGCGCGGTCGATAAAGATCGACTTGCCACCTTTCACTCTCATAGGTGCTACTACTCGT
ACAGGTTTGCTGACTGCGCCGCTGCGCGACCGTTTTGGTATCGTCCAGCGTTTGGAGTTCTATAGTCCTGAGGATCTTGC
TAGGATCGTAAGACGCTCGGCAGGCATTCTCAATATCGACTGTACTACGGAGGGTGCAGCTGAGATTGCGCAACGTGCAC
GCGGTACGCCTCGCATTGCTAATCGTTTGTTGCGGCGGGTACGCGATTATGCCGAGGTTAAGGCGGATGGGCAGATTACA
ATTGAGGTGGCGCAAGCAGCGATGCAGATGCTCAAGGTTGATCAAGGAGGCTTTGATGAACTAGACCGACGCTTGCTTCA
CACCATCGTTGAGTATTTCGACGGCGGTCCTGTCGGAATCGAGTCACTCGCTGCCTCGTTGTCGGAGGAGCGTGGTACCC
TTGAGGATGTCGTTGAGCCTTACCTAATTCAACAAGGTTTCTTGGTACGTACTGCACGTGGACGTATGGCCACAGATAAG
GCCTACCAGCATCTCGCTCTGCAGCCTCGTGAGCGAGTTTCGGCTTTCACTGATCCAGAAGATTTGTTTTGA

Upstream 100 bases:

>100_bases
AAACCGTTTGGTTGAACTTGGTACGCAAGTGGAAATCTGAGTAATGTTTATTCTCTAGCATTTCCGATTCCGTACTCTCC
TACCTTTCCTTACTTTATTT

Downstream 100 bases:

>100_bases
ACCATGAGAACTCCACTATGAGTAGCACTGTTACTCCACAGTTCAGTTGGATGACCCGTGTCTACTGGGAAGATACAGGT
GCTGACGGTGTTGTTTATCA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MDRIIDSAATREDEAIEVSIRPKRLADYLGQQPVREQMDIYIQATKARAEALDHVLIFGPPGLGKTTLSHVIAYELGVKL
RVTSGPVIEKAGDLAALLTNLQPYDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGEGPAARSIKIDLPPFTLIGATTR
TGLLTAPLRDRFGIVQRLEFYSPEDLARIVRRSAGILNIDCTTEGAAEIAQRARGTPRIANRLLRRVRDYAEVKADGQIT
IEVAQAAMQMLKVDQGGFDELDRRLLHTIVEYFDGGPVGIESLAASLSEERGTLEDVVEPYLIQQGFLVRTARGRMATDK
AYQHLALQPRERVSAFTDPEDLF

Sequences:

>Translated_343_residues
MDRIIDSAATREDEAIEVSIRPKRLADYLGQQPVREQMDIYIQATKARAEALDHVLIFGPPGLGKTTLSHVIAYELGVKL
RVTSGPVIEKAGDLAALLTNLQPYDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGEGPAARSIKIDLPPFTLIGATTR
TGLLTAPLRDRFGIVQRLEFYSPEDLARIVRRSAGILNIDCTTEGAAEIAQRARGTPRIANRLLRRVRDYAEVKADGQIT
IEVAQAAMQMLKVDQGGFDELDRRLLHTIVEYFDGGPVGIESLAASLSEERGTLEDVVEPYLIQQGFLVRTARGRMATDK
AYQHLALQPRERVSAFTDPEDLF
>Mature_343_residues
MDRIIDSAATREDEAIEVSIRPKRLADYLGQQPVREQMDIYIQATKARAEALDHVLIFGPPGLGKTTLSHVIAYELGVKL
RVTSGPVIEKAGDLAALLTNLQPYDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGEGPAARSIKIDLPPFTLIGATTR
TGLLTAPLRDRFGIVQRLEFYSPEDLARIVRRSAGILNIDCTTEGAAEIAQRARGTPRIANRLLRRVRDYAEVKADGQIT
IEVAQAAMQMLKVDQGGFDELDRRLLHTIVEYFDGGPVGIESLAASLSEERGTLEDVVEPYLIQQGFLVRTARGRMATDK
AYQHLALQPRERVSAFTDPEDLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=330, Percent_Identity=66.969696969697, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1787119, Length=233, Percent_Identity=30.0429184549356, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_XYLF2 (B2I4T1)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829650.1
- ProteinModelPortal:   B2I4T1
- SMR:   B2I4T1
- GeneID:   6202583
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0944
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38106; Mature: 38106

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIIDSAATREDEAIEVSIRPKRLADYLGQQPVREQMDIYIQATKARAEALDHVLIFGP
CCCHHHHHHCCCCCEEEEEECHHHHHHHHCCCCCHHHHHEEEEHHHHHHHHHCEEEEECC
PGLGKTTLSHVIAYELGVKLRVTSGPVIEKAGDLAALLTNLQPYDVLFIDEIHRLSPVVE
CCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
EVLYPAMEDFQIDIMIGEGPAARSIKIDLPPFTLIGATTRTGLLTAPLRDRFGIVQRLEF
HHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCCCCCEEECCHHHHHHHHHHHHC
YSPEDLARIVRRSAGILNIDCTTEGAAEIAQRARGTPRIANRLLRRVRDYAEVKADGQIT
CCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEE
IEVAQAAMQMLKVDQGGFDELDRRLLHTIVEYFDGGPVGIESLAASLSEERGTLEDVVEP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHH
YLIQQGFLVRTARGRMATDKAYQHLALQPRERVSAFTDPEDLF
HHHHCCCEEEECCCCCHHHHHHHHHHCCCHHHHHCCCCHHHCC
>Mature Secondary Structure
MDRIIDSAATREDEAIEVSIRPKRLADYLGQQPVREQMDIYIQATKARAEALDHVLIFGP
CCCHHHHHHCCCCCEEEEEECHHHHHHHHCCCCCHHHHHEEEEHHHHHHHHHCEEEEECC
PGLGKTTLSHVIAYELGVKLRVTSGPVIEKAGDLAALLTNLQPYDVLFIDEIHRLSPVVE
CCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
EVLYPAMEDFQIDIMIGEGPAARSIKIDLPPFTLIGATTRTGLLTAPLRDRFGIVQRLEF
HHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCCCCCEEECCHHHHHHHHHHHHC
YSPEDLARIVRRSAGILNIDCTTEGAAEIAQRARGTPRIANRLLRRVRDYAEVKADGQIT
CCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEE
IEVAQAAMQMLKVDQGGFDELDRRLLHTIVEYFDGGPVGIESLAASLSEERGTLEDVVEP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHH
YLIQQGFLVRTARGRMATDKAYQHLALQPRERVSAFTDPEDLF
HHHHCCCEEEECCCCCHHHHHHHHHHCCCHHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA