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The map label for this gene is mrdB [H]

Identifier: 182681149

GI number: 182681149

Start: 698959

End: 700080

Strand: Direct

Name: mrdB [H]

Synonym: XfasM23_0591

Alternate gene names: 182681149

Gene position: 698959-700080 (Clockwise)

Preceding gene: 182681148

Following gene: 182681150

Centisome position: 27.56

GC content: 50.09

Gene sequence:

>1122_bases
TTGAGGGATTTGCTGCGCTTGCTTGTGGATCTGGTGTTGCGCTTTACGCGCACTCTGGATTTGCCGCTGTGCTTGACTCT
TGGGGCATTGATGGTGATTGGACTGATGGTGATGCATAGTGCTGGTGCGGCGGTCACTGGCACCAGTCACTTGATGTTGT
CGCAGAGTGTGCGTTTTGCGTTTGGTCTGTTGATCATGTGGTGCTTGTCACGGGTTCCAGTGCCCCGTCTTCGTGCTTGG
AGTCCATTGGTATATGTGTTCTCAATGGTGCCGTTGATGGTGGTATTCATACTGGGTACCGGAAAATATGGGCGCCAGTG
GTTGGACCTTAAGCTATTTTATTTGCAGCCTGCTGAGCTGTTGAAAATCAGTTTGCCAATGATGATGGCTTGGTACCTTC
ATCGTATGCCACTGCCGCCACGTCTGTTTACGGTGATGGTCAGTTTCATGATTATTGGTATTCCGACTTCACTCATCATG
TTGCAGCCAGATTTTGGTACCAGTGTGCTGGTTGCCGCCTCTGGTATATTTGTGTTGTTGCTGGCTGGCTTGCCGTGGTG
GTGGATTGGAATCGGCGTCGTTAGTATTGCTATGATTGCACCGTTCAGTTGGTTCTGGTTGCTGCGTCCGTATCAAAAGG
ATCGCATCATGATGTTTCTGAATCCGGAGAACGACACACTTGGTGCGGGTTGGAACATTATTCAATCTAAGATTGCGATT
GGCTCGGGGGGGCTAGCCGGTAAGGGGTGGGGCCTTGGGACGCAGTCACATCTGAACTTTATTCCGGAGCAGACAACTGA
CTTTGCGTTTTCAGTATTGAGTGAAGAGTTTGGTTGGGTTGGTGTCACGACGGTGCTGATGTTGTATTTGTTCGTCATCA
TGCGCTGCTTGTGGATCGCAGGGCAAGCACGCGATACTTATTCTCGCTTGCTTGTTGGCGCGCTTGCTTTGTCTTTTTTT
GTCTATGTGTTGGTTAATGGCGGCATGATTTCAGGCTTACTACCTGTGGTGGGTGTACCAATGCCACTGATGAGTTATGG
CGGTACTTCGGCGGTTTCTTTACTGGTTGGTTTCGGTTTGGTCATGGGGGTGCGTTCGCATCGGAGAATGCATCATCGTT
GA

Upstream 100 bases:

>100_bases
TACAGGTTTCGGTTGCTGGTGGAATGCTAAATTCAACCGCCATGATGCCGGTTGCGCCACGTGCGCCAGTGACTCTCGAC
TCATTGCCGGAGGAAGACCC

Downstream 100 bases:

>100_bases
GCATTGTGATGAGGGAAAAAGTTAGCTATGTCTATCCAGCCTTTGGGTACGTTAGTCTCTCTTTATAATCCCAAGCCTGC
AGAACAAGTGGTTCTGTGTT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MRDLLRLLVDLVLRFTRTLDLPLCLTLGALMVIGLMVMHSAGAAVTGTSHLMLSQSVRFAFGLLIMWCLSRVPVPRLRAW
SPLVYVFSMVPLMVVFILGTGKYGRQWLDLKLFYLQPAELLKISLPMMMAWYLHRMPLPPRLFTVMVSFMIIGIPTSLIM
LQPDFGTSVLVAASGIFVLLLAGLPWWWIGIGVVSIAMIAPFSWFWLLRPYQKDRIMMFLNPENDTLGAGWNIIQSKIAI
GSGGLAGKGWGLGTQSHLNFIPEQTTDFAFSVLSEEFGWVGVTTVLMLYLFVIMRCLWIAGQARDTYSRLLVGALALSFF
VYVLVNGGMISGLLPVVGVPMPLMSYGGTSAVSLLVGFGLVMGVRSHRRMHHR

Sequences:

>Translated_373_residues
MRDLLRLLVDLVLRFTRTLDLPLCLTLGALMVIGLMVMHSAGAAVTGTSHLMLSQSVRFAFGLLIMWCLSRVPVPRLRAW
SPLVYVFSMVPLMVVFILGTGKYGRQWLDLKLFYLQPAELLKISLPMMMAWYLHRMPLPPRLFTVMVSFMIIGIPTSLIM
LQPDFGTSVLVAASGIFVLLLAGLPWWWIGIGVVSIAMIAPFSWFWLLRPYQKDRIMMFLNPENDTLGAGWNIIQSKIAI
GSGGLAGKGWGLGTQSHLNFIPEQTTDFAFSVLSEEFGWVGVTTVLMLYLFVIMRCLWIAGQARDTYSRLLVGALALSFF
VYVLVNGGMISGLLPVVGVPMPLMSYGGTSAVSLLVGFGLVMGVRSHRRMHHR
>Mature_373_residues
MRDLLRLLVDLVLRFTRTLDLPLCLTLGALMVIGLMVMHSAGAAVTGTSHLMLSQSVRFAFGLLIMWCLSRVPVPRLRAW
SPLVYVFSMVPLMVVFILGTGKYGRQWLDLKLFYLQPAELLKISLPMMMAWYLHRMPLPPRLFTVMVSFMIIGIPTSLIM
LQPDFGTSVLVAASGIFVLLLAGLPWWWIGIGVVSIAMIAPFSWFWLLRPYQKDRIMMFLNPENDTLGAGWNIIQSKIAI
GSGGLAGKGWGLGTQSHLNFIPEQTTDFAFSVLSEEFGWVGVTTVLMLYLFVIMRCLWIAGQARDTYSRLLVGALALSFF
VYVLVNGGMISGLLPVVGVPMPLMSYGGTSAVSLLVGFGLVMGVRSHRRMHHR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=329, Percent_Identity=48.6322188449848, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1786277, Length=379, Percent_Identity=30.8707124010554, Blast_Score=146, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41463; Mature: 41463

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS00228 TUBULIN_B_AUTOREG ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLLRLLVDLVLRFTRTLDLPLCLTLGALMVIGLMVMHSAGAAVTGTSHLMLSQSVRFA
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
FGLLIMWCLSRVPVPRLRAWSPLVYVFSMVPLMVVFILGTGKYGRQWLDLKLFYLQPAEL
HHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCHHCCHHHEEEEEEECHHHH
LKISLPMMMAWYLHRMPLPPRLFTVMVSFMIIGIPTSLIMLQPDFGTSVLVAASGIFVLL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHH
LAGLPWWWIGIGVVSIAMIAPFSWFWLLRPYQKDRIMMFLNPENDTLGAGWNIIQSKIAI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHC
GSGGLAGKGWGLGTQSHLNFIPEQTTDFAFSVLSEEFGWVGVTTVLMLYLFVIMRCLWIA
CCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GQARDTYSRLLVGALALSFFVYVLVNGGMISGLLPVVGVPMPLMSYGGTSAVSLLVGFGL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHH
VMGVRSHRRMHHR
HHHHHHHHHHCCC
>Mature Secondary Structure
MRDLLRLLVDLVLRFTRTLDLPLCLTLGALMVIGLMVMHSAGAAVTGTSHLMLSQSVRFA
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
FGLLIMWCLSRVPVPRLRAWSPLVYVFSMVPLMVVFILGTGKYGRQWLDLKLFYLQPAEL
HHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHCCCHHCCHHHEEEEEEECHHHH
LKISLPMMMAWYLHRMPLPPRLFTVMVSFMIIGIPTSLIMLQPDFGTSVLVAASGIFVLL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHH
LAGLPWWWIGIGVVSIAMIAPFSWFWLLRPYQKDRIMMFLNPENDTLGAGWNIIQSKIAI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHC
GSGGLAGKGWGLGTQSHLNFIPEQTTDFAFSVLSEEFGWVGVTTVLMLYLFVIMRCLWIA
CCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GQARDTYSRLLVGALALSFFVYVLVNGGMISGLLPVVGVPMPLMSYGGTSAVSLLVGFGL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHH
VMGVRSHRRMHHR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]