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The map label for this gene is yaeL [C]

Identifier: 182680885

GI number: 182680885

Start: 420197

End: 421531

Strand: Reverse

Name: yaeL [C]

Synonym: XfasM23_0323

Alternate gene names: 182680885

Gene position: 421531-420197 (Counterclockwise)

Preceding gene: 182680886

Following gene: 182680884

Centisome position: 16.62

GC content: 52.96

Gene sequence:

>1335_bases
ATGGGTGATTTCTTAGCATCTATCTGGTGGATGATCGTCAGCTTCAGTGTCCTGGTTACGTTCCACGAATTCGGGCATTA
CTGGGTCGCACGCCGCTGCGGCGTCAAAGTTCTACGCTTCTCAATCGGCTTCGGCACGCCGCTTTGGTCACGCCGCAGTA
GCTCAGGTACCGAATTTGTGATCGGCGCAATCCCACTGGGTGGATACGTGAAGATGCTGGATGAACGCGAGGCTGATGTA
ACAGTCGCGGAACGCAACCAAGCATTCAACCGTAAATCGGTATGGCAGCGTATCGCAATCGTCGCCGCCGGACCGCTCGC
CAACCTATTGCTATGCATGCTGCTGCTATGGGTACTGTTCGTGATCGGAAAGCAAGATTATTCAGCAACTGTGGGCCGTG
CCGAACACCTTGCTGCACAAGCCGGTATCCATCCTGGAGATCGCATCACAGCCATTGATGGTCGTCAGGTCACCAGCTGG
AGCGAAGCCAGCATGCTACTGACGGCCGCAGCCATGGATAGGCAGAATGCCGTTTTAAGCGTTATCGGACCTTACGGCGA
GCGCAGCGAGCACACCTTAGAATTATCAAAGCTAAAACAACCTTTTGATGAAAGGCACGTGACCGCACTGGTTGGCATAA
ACTGGCAATTCATGTTGCAGCCACCCATCATTGCGAAAATCGAACCTGGTTCAATCGCCGAAGGCGCCATAAAACCAGGG
GATATCGTCCTTGCCGTAGATGGACAACAGACCCTTTCCACCGAAGACCTATACAACCAAATTCAGAAACTGGGCCGCGA
TGGACATCCGGGAATGATAGAGATCAGGCGTGGTGAAGAACGCTTGGCGCTAGAACTCAGCCCTCGGAAGTCAGCACAGG
GAGTCTGGTTACTCGGTGTAAAGACTAATCCCGGACCGGTGCCAGCTTTCGACAGTCAACAACGCTATGGTGTACTTGCA
GCTGTACCGCTGGCAATCCGCGAGACCGCTCGGATGACCGCCGATTCATTGGGAATGATGAAACGGATCATCACTGGCCA
AGCATCGGCAAAAAATATCTCTGGCCCAATCAGCATCGCCAAGATCGCCAATGCATCAGCCAAACGAGGAGTAGGATGGT
TCATCTATTTTCTGTCGTTGCTATCACTCAGCTTAGCGATTATCAACCTGTTTCCAATACCAATATTGGATGGGGGGCAC
CTACTGTATTACGCTATCGAACTACTCAAAGGCAGCCCACTTAGCACACGTGCCATGGCCGCAGGCCAATACATCGGTTT
AGCGCTACTCGCCGGACTGATGGGGCTAGCGTTCTACAACGATCTGCTCGGCTGA

Upstream 100 bases:

>100_bases
CTCTACTGACCGTGGACACAGAAACCCGCCGCATCACACACGCAGCACTCACCCATTTCCCACTCCCTCTCTAATATCAC
AAACATCAATACAAAATCTT

Downstream 100 bases:

>100_bases
AGAACCGCTATGTGAGGTGAGACTGTGTTTAAGCGAAACTGTCGTCGTCATGCGTCGGCACCCTGTAACCCAAGTTATCG
ACACCAATCGGATTTAACAT

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MGDFLASIWWMIVSFSVLVTFHEFGHYWVARRCGVKVLRFSIGFGTPLWSRRSSSGTEFVIGAIPLGGYVKMLDEREADV
TVAERNQAFNRKSVWQRIAIVAAGPLANLLLCMLLLWVLFVIGKQDYSATVGRAEHLAAQAGIHPGDRITAIDGRQVTSW
SEASMLLTAAAMDRQNAVLSVIGPYGERSEHTLELSKLKQPFDERHVTALVGINWQFMLQPPIIAKIEPGSIAEGAIKPG
DIVLAVDGQQTLSTEDLYNQIQKLGRDGHPGMIEIRRGEERLALELSPRKSAQGVWLLGVKTNPGPVPAFDSQQRYGVLA
AVPLAIRETARMTADSLGMMKRIITGQASAKNISGPISIAKIANASAKRGVGWFIYFLSLLSLSLAIINLFPIPILDGGH
LLYYAIELLKGSPLSTRAMAAGQYIGLALLAGLMGLAFYNDLLG

Sequences:

>Translated_444_residues
MGDFLASIWWMIVSFSVLVTFHEFGHYWVARRCGVKVLRFSIGFGTPLWSRRSSSGTEFVIGAIPLGGYVKMLDEREADV
TVAERNQAFNRKSVWQRIAIVAAGPLANLLLCMLLLWVLFVIGKQDYSATVGRAEHLAAQAGIHPGDRITAIDGRQVTSW
SEASMLLTAAAMDRQNAVLSVIGPYGERSEHTLELSKLKQPFDERHVTALVGINWQFMLQPPIIAKIEPGSIAEGAIKPG
DIVLAVDGQQTLSTEDLYNQIQKLGRDGHPGMIEIRRGEERLALELSPRKSAQGVWLLGVKTNPGPVPAFDSQQRYGVLA
AVPLAIRETARMTADSLGMMKRIITGQASAKNISGPISIAKIANASAKRGVGWFIYFLSLLSLSLAIINLFPIPILDGGH
LLYYAIELLKGSPLSTRAMAAGQYIGLALLAGLMGLAFYNDLLG
>Mature_443_residues
GDFLASIWWMIVSFSVLVTFHEFGHYWVARRCGVKVLRFSIGFGTPLWSRRSSSGTEFVIGAIPLGGYVKMLDEREADVT
VAERNQAFNRKSVWQRIAIVAAGPLANLLLCMLLLWVLFVIGKQDYSATVGRAEHLAAQAGIHPGDRITAIDGRQVTSWS
EASMLLTAAAMDRQNAVLSVIGPYGERSEHTLELSKLKQPFDERHVTALVGINWQFMLQPPIIAKIEPGSIAEGAIKPGD
IVLAVDGQQTLSTEDLYNQIQKLGRDGHPGMIEIRRGEERLALELSPRKSAQGVWLLGVKTNPGPVPAFDSQQRYGVLAA
VPLAIRETARMTADSLGMMKRIITGQASAKNISGPISIAKIANASAKRGVGWFIYFLSLLSLSLAIINLFPIPILDGGHL
LYYAIELLKGSPLSTRAMAAGQYIGLALLAGLMGLAFYNDLLG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=454, Percent_Identity=39.8678414096916, Blast_Score=286, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48322; Mature: 48191

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDFLASIWWMIVSFSVLVTFHEFGHYWVARRCGVKVLRFSIGFGTPLWSRRSSSGTEFV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEE
IGAIPLGGYVKMLDEREADVTVAERNQAFNRKSVWQRIAIVAAGPLANLLLCMLLLWVLF
EEEECCCHHHHHHHCCCCCEEEEHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VIGKQDYSATVGRAEHLAAQAGIHPGDRITAIDGRQVTSWSEASMLLTAAAMDRQNAVLS
HHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCEECCHHHHHHHHHHHHHCCCCCEEE
VIGPYGERSEHTLELSKLKQPFDERHVTALVGINWQFMLQPPIIAKIEPGSIAEGAIKPG
EECCCCCCCCHHEEHHHHCCCCCCCCEEEEEECCEEEEECCCEEEEECCCCCCCCCCCCC
DIVLAVDGQQTLSTEDLYNQIQKLGRDGHPGMIEIRRGEERLALELSPRKSAQGVWLLGV
CEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEEE
KTNPGPVPAFDSQQRYGVLAAVPLAIRETARMTADSLGMMKRIITGQASAKNISGPISIA
ECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHH
KIANASAKRGVGWFIYFLSLLSLSLAIINLFPIPILDGGHLLYYAIELLKGSPLSTRAMA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCHHHHH
AGQYIGLALLAGLMGLAFYNDLLG
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GDFLASIWWMIVSFSVLVTFHEFGHYWVARRCGVKVLRFSIGFGTPLWSRRSSSGTEFV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEE
IGAIPLGGYVKMLDEREADVTVAERNQAFNRKSVWQRIAIVAAGPLANLLLCMLLLWVLF
EEEECCCHHHHHHHCCCCCEEEEHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VIGKQDYSATVGRAEHLAAQAGIHPGDRITAIDGRQVTSWSEASMLLTAAAMDRQNAVLS
HHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCEECCHHHHHHHHHHHHHCCCCCEEE
VIGPYGERSEHTLELSKLKQPFDERHVTALVGINWQFMLQPPIIAKIEPGSIAEGAIKPG
EECCCCCCCCHHEEHHHHCCCCCCCCEEEEEECCEEEEECCCEEEEECCCCCCCCCCCCC
DIVLAVDGQQTLSTEDLYNQIQKLGRDGHPGMIEIRRGEERLALELSPRKSAQGVWLLGV
CEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEEE
KTNPGPVPAFDSQQRYGVLAAVPLAIRETARMTADSLGMMKRIITGQASAKNISGPISIA
ECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHH
KIANASAKRGVGWFIYFLSLLSLSLAIINLFPIPILDGGHLLYYAIELLKGSPLSTRAMA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCHHHHH
AGQYIGLALLAGLMGLAFYNDLLG
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]