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The map label for this gene is htpG [H]

Identifier: 182680831

GI number: 182680831

Start: 348977

End: 350887

Strand: Reverse

Name: htpG [H]

Synonym: XfasM23_0266

Alternate gene names: 182680831

Gene position: 350887-348977 (Counterclockwise)

Preceding gene: 182680838

Following gene: 182680828

Centisome position: 13.84

GC content: 52.9

Gene sequence:

>1911_bases
ATGACCCTCGAAGCAGACAAACAGACCCACGGCTTCCAAACGGAAGTCAAACAGTTACTACAACTGATGATCCACTCCCT
GTACTCAAACAAGGAGATTTTCCTACGCGAATTAATCTCCAATGCTGCCGATGCTGCGGACAAACTGCGCTTTGAGGCAT
TGAGCGCCCCCTCATTACTGGAAGAAGATCCCAACCTGCGCATCCGCGTTGAGTTTGATAAACAAGCACACACCATCACC
ATTGATGACAACGGCATTGGGATGAGTCGTGATGAGGCCATTGCACACCTGGGCACGATTGCCAAGTCAGGCACCGCCGA
TTTCCTCAAAGCACTGTCTGGCGATCAACGCAAAGACGCCAACCTCATTGGCCAATTCGGTGTCGGCTTCTACAGTGCCT
TTATTGTCGCCGACCACGTCGACGTCTACAGCCGCCGCGCCGGACTGACAGCAGCCGAGGGCGTACACTGGTCGAGCAAA
GGTGAAGGCAACTTTGAAGTGGCCACCATTGATAAACCGCAACGCGGCACCCGCGTCGTGCTCCACCTGAAAGAAAATGA
GCAACACTTTGCAGAAGGATGGACCCTGCGCAGCACCCTGAAAAAATATTCCGACCACATCGGCCTCCCCATTGAAATGC
TCAAGGAACACCACGGCAAGGAGGAAGAAAAAGACACCCCCCAAGAAGCCGAGTGGGAAGCCGTCAACAAAGCCAGCGCC
CTATGGACACGCCCCAAAAACGACATCAAGGATGAGGAATACCAGGAATTCTACAAACACATCTCACACGATATGACCAA
CCCGCTCGCCTGGAGCCATAACAAGGTCGAAGGCAAGCTGGAATACACCTCCTTACTCTATGTCCCAACACGCGCACCAT
TTGACCTGTACCACCGCAATGCTGCCAAGGGACTGAAACTGTATGTACAACGTGTTTTCATCATGGATCAAGCGGAACAG
TTCCTGCCGCTCTACCTGCGTTTCATCAAGGGCGTTGTTGACTCTGCCGACCTCTCGCTGAACGTCTCCCGCGAGATCCT
CCAATCTGGCCCAGTCGTGGACTCCATGAAAACCGCACTGAGCAAACGCGCCCTGGACATGCTTGAAAAACTCGCCAAAG
ACGCCCCAGAAGATTACAAAACCTTCTGGAAAAACTTTGGCCAGGTACTGAAAGAAGGACCCGCCGAGGATTACAGCAAC
CGCGAGAAAGTCGCCAGCCTGCTGCGCTTTGCCTCAACCTACGACACCTCCGGTGATCCCTCCGTCGCACTCACCGATTA
CATCGCACGCATGAAAGAAGGTCAGGACAAGCTCTACTACCTGACCGGAGAATCCTACGCACAAATCAAGGACAGCCCAT
ACCTGGAAGTATTCCGTAAAAAAGGCATTGAAGTACTGCTACTGGTAGACCGCATTGACGAGTGGTTGATGAACTACTTA
CATGAATTCGACGGAAAATCCTTTGTCGACATTGCACGCGGCGATCTGGACCTCGGAAACCTCGACAGCGAAGCAGACAA
AAAAGCACAAGAGGAAATCGCAAAAACAAAAGAAGCATTAGCCAGCCGGATCAAAGCCACACTAGGAGAAGATGTTGCCG
AAGTGCGCGTCTCACATCGCCTGACCGATTCACCCGCAGTACTCGCCATCGGCGAAGGCGATCTCGGCCTGCAAATGCGT
CAGTTACTCGAAGCTAGCGGCCAGAAAGTTCCAGAAACAAAACCCGTCTTCGAATTCAACCCAAGCCACCCACTCATCGA
AAAACTGGACGCCGAACAAGACATGGACCGTTTTGCAGACCTGAGCCGCATCCTGTTCGATCAAGCCGCACTCGCTGCCG
GAGACAGTTTGAAAGACCCGGCCAACTACGTGCGCCGCCTCAACAAACTCCTACTGGAACTATCGGCCTAA

Upstream 100 bases:

>100_bases
CTCCCGACTGACCAGAAACCTTGAAAGCATCACCGACGACCCATACCCCCTCGCCATCCCCGCATCGAATGCGGCACACC
TTTTATGGAGCTTAACAACG

Downstream 100 bases:

>100_bases
AAAAACAACATTGATACAACGGGCAGCACAGCAACACGCCCGCAGCAACACACCAACAATGCCCCTGAATGTTCAGGGGC
ATTGTCCTTCAGGCGCTACA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MTLEADKQTHGFQTEVKQLLQLMIHSLYSNKEIFLRELISNAADAADKLRFEALSAPSLLEEDPNLRIRVEFDKQAHTIT
IDDNGIGMSRDEAIAHLGTIAKSGTADFLKALSGDQRKDANLIGQFGVGFYSAFIVADHVDVYSRRAGLTAAEGVHWSSK
GEGNFEVATIDKPQRGTRVVLHLKENEQHFAEGWTLRSTLKKYSDHIGLPIEMLKEHHGKEEEKDTPQEAEWEAVNKASA
LWTRPKNDIKDEEYQEFYKHISHDMTNPLAWSHNKVEGKLEYTSLLYVPTRAPFDLYHRNAAKGLKLYVQRVFIMDQAEQ
FLPLYLRFIKGVVDSADLSLNVSREILQSGPVVDSMKTALSKRALDMLEKLAKDAPEDYKTFWKNFGQVLKEGPAEDYSN
REKVASLLRFASTYDTSGDPSVALTDYIARMKEGQDKLYYLTGESYAQIKDSPYLEVFRKKGIEVLLLVDRIDEWLMNYL
HEFDGKSFVDIARGDLDLGNLDSEADKKAQEEIAKTKEALASRIKATLGEDVAEVRVSHRLTDSPAVLAIGEGDLGLQMR
QLLEASGQKVPETKPVFEFNPSHPLIEKLDAEQDMDRFADLSRILFDQAALAAGDSLKDPANYVRRLNKLLLELSA

Sequences:

>Translated_636_residues
MTLEADKQTHGFQTEVKQLLQLMIHSLYSNKEIFLRELISNAADAADKLRFEALSAPSLLEEDPNLRIRVEFDKQAHTIT
IDDNGIGMSRDEAIAHLGTIAKSGTADFLKALSGDQRKDANLIGQFGVGFYSAFIVADHVDVYSRRAGLTAAEGVHWSSK
GEGNFEVATIDKPQRGTRVVLHLKENEQHFAEGWTLRSTLKKYSDHIGLPIEMLKEHHGKEEEKDTPQEAEWEAVNKASA
LWTRPKNDIKDEEYQEFYKHISHDMTNPLAWSHNKVEGKLEYTSLLYVPTRAPFDLYHRNAAKGLKLYVQRVFIMDQAEQ
FLPLYLRFIKGVVDSADLSLNVSREILQSGPVVDSMKTALSKRALDMLEKLAKDAPEDYKTFWKNFGQVLKEGPAEDYSN
REKVASLLRFASTYDTSGDPSVALTDYIARMKEGQDKLYYLTGESYAQIKDSPYLEVFRKKGIEVLLLVDRIDEWLMNYL
HEFDGKSFVDIARGDLDLGNLDSEADKKAQEEIAKTKEALASRIKATLGEDVAEVRVSHRLTDSPAVLAIGEGDLGLQMR
QLLEASGQKVPETKPVFEFNPSHPLIEKLDAEQDMDRFADLSRILFDQAALAAGDSLKDPANYVRRLNKLLLELSA
>Mature_635_residues
TLEADKQTHGFQTEVKQLLQLMIHSLYSNKEIFLRELISNAADAADKLRFEALSAPSLLEEDPNLRIRVEFDKQAHTITI
DDNGIGMSRDEAIAHLGTIAKSGTADFLKALSGDQRKDANLIGQFGVGFYSAFIVADHVDVYSRRAGLTAAEGVHWSSKG
EGNFEVATIDKPQRGTRVVLHLKENEQHFAEGWTLRSTLKKYSDHIGLPIEMLKEHHGKEEEKDTPQEAEWEAVNKASAL
WTRPKNDIKDEEYQEFYKHISHDMTNPLAWSHNKVEGKLEYTSLLYVPTRAPFDLYHRNAAKGLKLYVQRVFIMDQAEQF
LPLYLRFIKGVVDSADLSLNVSREILQSGPVVDSMKTALSKRALDMLEKLAKDAPEDYKTFWKNFGQVLKEGPAEDYSNR
EKVASLLRFASTYDTSGDPSVALTDYIARMKEGQDKLYYLTGESYAQIKDSPYLEVFRKKGIEVLLLVDRIDEWLMNYLH
EFDGKSFVDIARGDLDLGNLDSEADKKAQEEIAKTKEALASRIKATLGEDVAEVRVSHRLTDSPAVLAIGEGDLGLQMRQ
LLEASGQKVPETKPVFEFNPSHPLIEKLDAEQDMDRFADLSRILFDQAALAAGDSLKDPANYVRRLNKLLLELSA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=681, Percent_Identity=38.1791483113069, Blast_Score=434, Evalue=1e-121,
Organism=Homo sapiens, GI4507677, Length=687, Percent_Identity=36.8267831149927, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI155722983, Length=646, Percent_Identity=34.5201238390093, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=38.5365853658537, Blast_Score=284, Evalue=2e-76,
Organism=Homo sapiens, GI153792590, Length=410, Percent_Identity=38.5365853658537, Blast_Score=281, Evalue=1e-75,
Organism=Escherichia coli, GI1786679, Length=626, Percent_Identity=58.9456869009585, Blast_Score=763, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=673, Percent_Identity=38.3358098068351, Blast_Score=451, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17542208, Length=677, Percent_Identity=36.1890694239291, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI115535205, Length=654, Percent_Identity=33.4862385321101, Blast_Score=327, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI115535167, Length=438, Percent_Identity=34.9315068493151, Blast_Score=256, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6323840, Length=680, Percent_Identity=38.9705882352941, Blast_Score=451, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6325016, Length=684, Percent_Identity=38.3040935672515, Blast_Score=446, Evalue=1e-126,
Organism=Drosophila melanogaster, GI17647529, Length=682, Percent_Identity=38.2697947214076, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI21357739, Length=676, Percent_Identity=37.5739644970414, Blast_Score=407, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24586016, Length=652, Percent_Identity=33.7423312883436, Blast_Score=365, Evalue=1e-101,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71746; Mature: 71615

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEADKQTHGFQTEVKQLLQLMIHSLYSNKEIFLRELISNAADAADKLRFEALSAPSLL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
EEDPNLRIRVEFDKQAHTITIDDNGIGMSRDEAIAHLGTIAKSGTADFLKALSGDQRKDA
CCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCH
NLIGQFGVGFYSAFIVADHVDVYSRRAGLTAAEGVHWSSKGEGNFEVATIDKPQRGTRVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCEEEEECCCCCCCCEEE
LHLKENEQHFAEGWTLRSTLKKYSDHIGLPIEMLKEHHGKEEEKDTPQEAEWEAVNKASA
EEEECCCHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LWTRPKNDIKDEEYQEFYKHISHDMTNPLAWSHNKVEGKLEYTSLLYVPTRAPFDLYHRN
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHH
AAKGLKLYVQRVFIMDQAEQFLPLYLRFIKGVVDSADLSLNVSREILQSGPVVDSMKTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHCCCCHHHHHHHH
SKRALDMLEKLAKDAPEDYKTFWKNFGQVLKEGPAEDYSNREKVASLLRFASTYDTSGDP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
SVALTDYIARMKEGQDKLYYLTGESYAQIKDSPYLEVFRKKGIEVLLLVDRIDEWLMNYL
CHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHH
HEFDGKSFVDIARGDLDLGNLDSEADKKAQEEIAKTKEALASRIKATLGEDVAEVRVSHR
HHHCCCCEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTDSPAVLAIGEGDLGLQMRQLLEASGQKVPETKPVFEFNPSHPLIEKLDAEQDMDRFAD
CCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHCCHHHHHHHHH
LSRILFDQAALAAGDSLKDPANYVRRLNKLLLELSA
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLEADKQTHGFQTEVKQLLQLMIHSLYSNKEIFLRELISNAADAADKLRFEALSAPSLL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
EEDPNLRIRVEFDKQAHTITIDDNGIGMSRDEAIAHLGTIAKSGTADFLKALSGDQRKDA
CCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCH
NLIGQFGVGFYSAFIVADHVDVYSRRAGLTAAEGVHWSSKGEGNFEVATIDKPQRGTRVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCEEEEECCCCCCCCEEE
LHLKENEQHFAEGWTLRSTLKKYSDHIGLPIEMLKEHHGKEEEKDTPQEAEWEAVNKASA
EEEECCCHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LWTRPKNDIKDEEYQEFYKHISHDMTNPLAWSHNKVEGKLEYTSLLYVPTRAPFDLYHRN
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHH
AAKGLKLYVQRVFIMDQAEQFLPLYLRFIKGVVDSADLSLNVSREILQSGPVVDSMKTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHCCCCHHHHHHHH
SKRALDMLEKLAKDAPEDYKTFWKNFGQVLKEGPAEDYSNREKVASLLRFASTYDTSGDP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
SVALTDYIARMKEGQDKLYYLTGESYAQIKDSPYLEVFRKKGIEVLLLVDRIDEWLMNYL
CHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHH
HEFDGKSFVDIARGDLDLGNLDSEADKKAQEEIAKTKEALASRIKATLGEDVAEVRVSHR
HHHCCCCEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTDSPAVLAIGEGDLGLQMRQLLEASGQKVPETKPVFEFNPSHPLIEKLDAEQDMDRFAD
CCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHCCHHHHHHHHH
LSRILFDQAALAAGDSLKDPANYVRRLNKLLLELSA
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]