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The map label for this gene is nuoN [H]

Identifier: 182680818

GI number: 182680818

Start: 330951

End: 332408

Strand: Direct

Name: nuoN [H]

Synonym: XfasM23_0253

Alternate gene names: 182680818

Gene position: 330951-332408 (Clockwise)

Preceding gene: 182680817

Following gene: 182680822

Centisome position: 13.05

GC content: 49.38

Gene sequence:

>1458_bases
ATGACCATGCCGACATCTGGGTTAAACATTGCCGATCTGGCTCCCTTGTTGCCGGAGCTAGTCCTTCTAGCTAGTACCTT
TGCATTGTTGATGATCGATCTATTTATCGGTCAAGTGCGGAAGGTTTGGACGCATTTTCTTTCGGTTGCGATTTTGGTTG
TTGTGTTGTCCATGTTAGTCGCCGGTGTTGGCGGGCAAGGTGCAGCGTTTCATGGGATGTTTGTGCGTGATAGCGCTGCC
GATATGATGAAAGTAGTGATTGTCTTGGTCAGCGCCCTAAGTTTGGTTTACGGGTGGAGTTACTTGCGTGAGCGCAACTT
GTTCCAGGGTGAAATTCCAGTGCTCGTGTTGTTTGCCACCTTGGGGATGATGGTCCTGGTGTCTGCGGGTCACTTGCTGA
TGGTGTACCTGGGGCTTGAGCTGTTGGCGCTTTGTTCCTATGCGTTGGTTGCGGTCAATCGCGATAGCAAAATATCGACT
GAGGCAGCGATGAAGTACATCGTGCTTGGTTCGTTGGCCTCTGGTTTGCTGTTATATGGAATGTCTTTGATTTATGGCGC
CACTGGCACACTCAGTCTGCCTGGTATCAGCGATGTGATCCATGGTTCATCGGAAAAGACGCTGCTGTTGACGGGTACGG
TATTTTTGATTGCCGGAGTAGCTTTTAAACTTGGTGCCGTGCCGTTTCATATGTGGTTGCCCGATGTGTATCAAGGGGCG
CCGACACCCATTGTTTTGTTTATCAGTTCGGCGCCAAAGTTGGCAGCATTCGGTATGGCTTATCGACTATTGGAAGTGGG
TGTCGGTCCATTGTCCCCGCAGTGGCATTTGATTTTTGGTGGTCTGGCGGCGCTCTCCTTGGTGATTGGCAATCTGATGG
CGATTGTGCAGACCAACTTGAAGCGTATGCTGGCTTACTCGACTGTCTCTCATGTCGGTTTTTTGATGATGGGTATGTCT
GGTGGCGGTATACGCGGTTATTCCTCGTCCATGTTCTATGTGTTGAGTTACGCAATCATGTCTACCGCTTCGTTTGGAGC
GATTATTGCGATGTCAAGTCGCGGTTCCGAGGCTGAGAATATTGACGACTTTAAAGGATTGAGCACGCGTCATCCTTGGA
TGGCGTGCTTGCTCTTATGTGTCATGGCTTCGTTAGCTGGTATTCCTCCTTTCTTAGGATTTTGGACAAAATTGGCTGTG
CTCGGTGCTGCAGTTCAGGGGGGCATGCTGTGGTTGGCGATTCTTGGGGTGATCTGTGCGGTGATTGGTGCTTACTATTA
TCTTCGTGTCATTAAAGTGATGTATTTTGATGAGCCCGTTGGTGAGCCGCTCCCAGTGAATGATGGTCGTGTTCTGAGAG
TCATTCTGAGTATTAATGTGTTTGCTCTGTTGGCTTTAGGAATCCTTTGGAACCCGATCATTGATTGGTGCCAGAAGGCA
TTTGCTCATCTGGTCTGA

Upstream 100 bases:

>100_bases
CTTATTGATTTGATGGATTCTTCCATTGTCAAGCTCACTACTCAGATTGCCGTGAGCAAGCTGTGATCGGCTGCGGCACA
ATTGATTTCAGGATTCGATA

Downstream 100 bases:

>100_bases
AGATTCCCAGTCATCACAGTATAGAAAGTCACGCAGCTTTTGCTTGTTTTTAATTTTAATTGGCTTGTTGGAATGGGACG
TCGGTGCGTTGTTCTCTCGG

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTMPTSGLNIADLAPLLPELVLLASTFALLMIDLFIGQVRKVWTHFLSVAILVVVLSMLVAGVGGQGAAFHGMFVRDSAA
DMMKVVIVLVSALSLVYGWSYLRERNLFQGEIPVLVLFATLGMMVLVSAGHLLMVYLGLELLALCSYALVAVNRDSKIST
EAAMKYIVLGSLASGLLLYGMSLIYGATGTLSLPGISDVIHGSSEKTLLLTGTVFLIAGVAFKLGAVPFHMWLPDVYQGA
PTPIVLFISSAPKLAAFGMAYRLLEVGVGPLSPQWHLIFGGLAALSLVIGNLMAIVQTNLKRMLAYSTVSHVGFLMMGMS
GGGIRGYSSSMFYVLSYAIMSTASFGAIIAMSSRGSEAENIDDFKGLSTRHPWMACLLLCVMASLAGIPPFLGFWTKLAV
LGAAVQGGMLWLAILGVICAVIGAYYYLRVIKVMYFDEPVGEPLPVNDGRVLRVILSINVFALLALGILWNPIIDWCQKA
FAHLV

Sequences:

>Translated_485_residues
MTMPTSGLNIADLAPLLPELVLLASTFALLMIDLFIGQVRKVWTHFLSVAILVVVLSMLVAGVGGQGAAFHGMFVRDSAA
DMMKVVIVLVSALSLVYGWSYLRERNLFQGEIPVLVLFATLGMMVLVSAGHLLMVYLGLELLALCSYALVAVNRDSKIST
EAAMKYIVLGSLASGLLLYGMSLIYGATGTLSLPGISDVIHGSSEKTLLLTGTVFLIAGVAFKLGAVPFHMWLPDVYQGA
PTPIVLFISSAPKLAAFGMAYRLLEVGVGPLSPQWHLIFGGLAALSLVIGNLMAIVQTNLKRMLAYSTVSHVGFLMMGMS
GGGIRGYSSSMFYVLSYAIMSTASFGAIIAMSSRGSEAENIDDFKGLSTRHPWMACLLLCVMASLAGIPPFLGFWTKLAV
LGAAVQGGMLWLAILGVICAVIGAYYYLRVIKVMYFDEPVGEPLPVNDGRVLRVILSINVFALLALGILWNPIIDWCQKA
FAHLV
>Mature_484_residues
TMPTSGLNIADLAPLLPELVLLASTFALLMIDLFIGQVRKVWTHFLSVAILVVVLSMLVAGVGGQGAAFHGMFVRDSAAD
MMKVVIVLVSALSLVYGWSYLRERNLFQGEIPVLVLFATLGMMVLVSAGHLLMVYLGLELLALCSYALVAVNRDSKISTE
AAMKYIVLGSLASGLLLYGMSLIYGATGTLSLPGISDVIHGSSEKTLLLTGTVFLIAGVAFKLGAVPFHMWLPDVYQGAP
TPIVLFISSAPKLAAFGMAYRLLEVGVGPLSPQWHLIFGGLAALSLVIGNLMAIVQTNLKRMLAYSTVSHVGFLMMGMSG
GGIRGYSSSMFYVLSYAIMSTASFGAIIAMSSRGSEAENIDDFKGLSTRHPWMACLLLCVMASLAGIPPFLGFWTKLAVL
GAAVQGGMLWLAILGVICAVIGAYYYLRVIKVMYFDEPVGEPLPVNDGRVLRVILSINVFALLALGILWNPIIDWCQKAF
AHLV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=321, Percent_Identity=24.6105919003115, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI145693160, Length=450, Percent_Identity=35.7777777777778, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1788614, Length=368, Percent_Identity=26.9021739130435, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788831, Length=381, Percent_Identity=25.7217847769029, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1788829, Length=345, Percent_Identity=27.2463768115942, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788827, Length=279, Percent_Identity=29.3906810035842, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788613, Length=331, Percent_Identity=25.9818731117825, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 51873; Mature: 51742

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCC
>Mature Secondary Structure 
TMPTSGLNIADLAPLLPELVLLASTFALLMIDLFIGQVRKVWTHFLSVAILVVVLSMLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA