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The map label for this gene is tctD [H]

Identifier: 182680822

GI number: 182680822

Start: 336768

End: 337463

Strand: Direct

Name: tctD [H]

Synonym: XfasM23_0257

Alternate gene names: 182680822

Gene position: 336768-337463 (Clockwise)

Preceding gene: 182680818

Following gene: 182680823

Centisome position: 13.28

GC content: 53.16

Gene sequence:

>696_bases
ATGCGCCTATTGTTGATTGAGGACAATGCTGATCTTGCCGATGCGATCATCCGGCGCATGCGGCGTCACGGTCATGCGGT
GGATTGGCAGAGCGATGGTCTAGCTGCTGCGGGCGTGTTGCGTTACCAGCGCTTTGACCTGGTGGTGTTGGATATTGGCT
TACCCAGTTTGGATGGCTTGCAGTTGCTGAGTGAGTTGCGCCAGCGTGGCGACACGACACCGGTGCTGATACTGACGGCA
CGTGATGCCATTGAAGATCGTGTGTATACGTTGAATGTTGGTGCCGACGACTACTTGAGCAAACCGTTCGACTTTCGTGA
GTTTGAGGCGCGTTGCCGTGTCTTGTTGCGTCGTAACCGTGGTAATGCCAGTGAAGTGGTGCGGATTGGCGGCTTTGAGT
TTGATAATGCAGCGCATCGCATCTGTTTGAACGGTGAGCCGATCAAATTACCTAATCGTGAATACCGGCTTCTGGAGATA
TTGATTGCCCGGTTGGGTCAAATCGTGGGTAAAGACGAGATTGGCAACAGCTTGTTCAATTTTGATGACAATGCCGGGCC
GAATGCGATTGAACTTTATGTGGCACGGTTGCGTAGGAAATTGGAAGCGGCGCCACTGCGTATCGTGACTGTGCGTCGTG
CAGGCTATCTCCTCGAACCGATCGTTGAGGCTAGGGGCCATGAAGCGTGCGATTAA

Upstream 100 bases:

>100_bases
CGCCAAGCCACGGACAGACATTGAATATCAAGAGTGAGGTGTCACTGCATTGAGGTACGCACGTTGGTCTTTACGAAGCC
CTTGGATTTGATGAGATTCA

Downstream 100 bases:

>100_bases
CGGTGGTTCGATCCGCCGTACCTTGTGGTTGTATCTCGGCGCATTCTCGATGATGAGCACCGTGTTCCTGTTCTTTGCCG
CGCGTGACTACGGGCAGCGT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRLLLIEDNADLADAIIRRMRRHGHAVDWQSDGLAAAGVLRYQRFDLVVLDIGLPSLDGLQLLSELRQRGDTTPVLILTA
RDAIEDRVYTLNVGADDYLSKPFDFREFEARCRVLLRRNRGNASEVVRIGGFEFDNAAHRICLNGEPIKLPNREYRLLEI
LIARLGQIVGKDEIGNSLFNFDDNAGPNAIELYVARLRRKLEAAPLRIVTVRRAGYLLEPIVEARGHEACD

Sequences:

>Translated_231_residues
MRLLLIEDNADLADAIIRRMRRHGHAVDWQSDGLAAAGVLRYQRFDLVVLDIGLPSLDGLQLLSELRQRGDTTPVLILTA
RDAIEDRVYTLNVGADDYLSKPFDFREFEARCRVLLRRNRGNASEVVRIGGFEFDNAAHRICLNGEPIKLPNREYRLLEI
LIARLGQIVGKDEIGNSLFNFDDNAGPNAIELYVARLRRKLEAAPLRIVTVRRAGYLLEPIVEARGHEACD
>Mature_231_residues
MRLLLIEDNADLADAIIRRMRRHGHAVDWQSDGLAAAGVLRYQRFDLVVLDIGLPSLDGLQLLSELRQRGDTTPVLILTA
RDAIEDRVYTLNVGADDYLSKPFDFREFEARCRVLLRRNRGNASEVVRIGGFEFDNAAHRICLNGEPIKLPNREYRLLEI
LIARLGQIVGKDEIGNSLFNFDDNAGPNAIELYVARLRRKLEAAPLRIVTVRRAGYLLEPIVEARGHEACD

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=41.2844036697248, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=38.0733944954128, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=38.0090497737557, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=34.8623853211009, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=34.2342342342342, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1790860, Length=203, Percent_Identity=34.4827586206897, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=30.9090909090909, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786911, Length=170, Percent_Identity=37.6470588235294, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=30.1310043668122, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=30.0884955752212, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=32.3144104803493, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788394, Length=204, Percent_Identity=30.3921568627451, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=29.4642857142857, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=26.1802575107296, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790437, Length=132, Percent_Identity=30.3030303030303, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=30.8411214953271, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=103, Percent_Identity=35.9223300970874, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26113; Mature: 26113

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLIEDNADLADAIIRRMRRHGHAVDWQSDGLAAAGVLRYQRFDLVVLDIGLPSLDGL
CEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHEEEEEEEEEECCCCCCCHH
QLLSELRQRGDTTPVLILTARDAIEDRVYTLNVGADDYLSKPFDFREFEARCRVLLRRNR
HHHHHHHHCCCCCCEEEEEECHHHHCEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHCCC
GNASEVVRIGGFEFDNAAHRICLNGEPIKLPNREYRLLEILIARLGQIVGKDEIGNSLFN
CCHHHEEEECCEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCHHCC
FDDNAGPNAIELYVARLRRKLEAAPLRIVTVRRAGYLLEPIVEARGHEACD
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRLLLIEDNADLADAIIRRMRRHGHAVDWQSDGLAAAGVLRYQRFDLVVLDIGLPSLDGL
CEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHEEEEEEEEEECCCCCCCHH
QLLSELRQRGDTTPVLILTARDAIEDRVYTLNVGADDYLSKPFDFREFEARCRVLLRRNR
HHHHHHHHCCCCCCEEEEEECHHHHCEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHCCC
GNASEVVRIGGFEFDNAAHRICLNGEPIKLPNREYRLLEILIARLGQIVGKDEIGNSLFN
CCHHHEEEECCEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCHHCC
FDDNAGPNAIELYVARLRRKLEAAPLRIVTVRRAGYLLEPIVEARGHEACD
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]