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The map label for this gene is bioA [H]

Identifier: 182680713

GI number: 182680713

Start: 196677

End: 198134

Strand: Direct

Name: bioA [H]

Synonym: XfasM23_0142

Alternate gene names: 182680713

Gene position: 196677-198134 (Clockwise)

Preceding gene: 182680705

Following gene: 182680714

Centisome position: 7.76

GC content: 55.42

Gene sequence:

>1458_bases
ATGCATCACAATGTTCATCAATCTGAAATCCTAGCAGATCCATGCGATCTTCAGCGGGCTGAACGCTGGCGACAACGCGA
TTTGCGCGTTCTGTGGCATCCGTGCACGCAAATGCGTGAGCATCCCGACACACTGCCATTAGTGCCCATCGTCCGTGGTG
AGGGTGTGTGGTTGGTCGGTCACGATGGGCGTCGTTACCTGGATGCTGTCAGTAGTTGGTGGACAAATCTTTTCGGTCAT
GCAGATCCCCGTATCAGTGCAGCAATCGCCGCACAGGCCAGGACGCTTGAGCACGTGATGTTGGCTGGTTTCAGCCATGA
GCCGGCGGTGCGTCTGGCCGAGGCCTTGTTGCGGCTCGCGCCGCGCCAGGACGGGCGTGAGCCCTTGTCAAAGGTGTTTT
ACGCTGACAATGGCTCGGCTGGGGTGGAAGTCGCGCTGAAAATGGCTTTCCATTACTTCCGTAATCGTGGTGAAGAGCAA
CGTACGCGATTTATCGCGTTACATAACGGGTATCACGGAGAAACCATTGGTGCTCTCGCGGTTGGCGATATCCCCTTGTA
CCGGCGTGTTTATGCTCCATTGCTAACGGAGGTATTGTTTGCTCCCTCTCCTGATGCCTATTTGGCCGAACCAGGTCAAA
GCGCCGCAGAATATGCATTACAGGCCGCCGAAGCGTTGGAAGCGCTATTCAAACGTTACTCGGGGCAAATCTGCGCGCTG
ATTTTAGAGCCACTTTTACAATGTGCAGGTGGCATGCGCATGCACCATCCGGTGTACCTACATCGTGTGCGGGAACTATG
CGATGCACACGGTGCCTTGCTGATTTGCGATGAGATTGCTACAGGGTTCGGACGCACTGGCACGCTCTTCGCTTGCGAGC
AGGCTTGCTCCGCTATCTCAACGGATACTGATGACAAGGATCTTGGCATCATGCCGGACTTGTTGTGTCTTTCCAAGGGG
CTGACGGGGGGGTTCCTACCTCTGGCCGCAGTGCTGACAACGCAGCAATTGTACGAGGAATTTCTCGATGACAGCCGCGA
ACGCGCTTTTCTGCATTCACACAGCTACACAGGAAATCCACTGGCTTGTATTGCAGCGCTAACGACACTGGATATCTTCG
AAAATGATTGCATCATCGAACGCAACCAAGTCACTGCAGCACGTATGACGCAATTGGCTGCGTCACTGTCCGGGCATCCG
CACGTTGCTGACGTGCGCCAGACCGGGATGGTCGTGGCATTTGAGTTAACTCGTGACGGCAACAAGCGGACACCATTCCC
GCCACAGGCACGGCTTGGCTTGCACGTTTACCGTGCTGCGCTGGCGCGTGGAGTGATCCTGCGTCCGCTTGGTGATGTGG
TGTATTGGATGCCTCCCTATTGCGTGGATGAGCAGCAACTGCATCTGCTTGCTGAGACCACGCGTGTGGCAATTGACGAA
GCTATCGCATGCGTTTGA

Upstream 100 bases:

>100_bases
CGAAATTGGCTATCACCGATTTCCTCAATGCGATGGATCATCGGCAGAGGGCGGTTCATGCCAGACACACACCGGCAGGA
GTGGCATATACAATGAGTTG

Downstream 100 bases:

>100_bases
GTCGTTGTCATGTCAATGTGCCCCTGATTCTTGGCAACGAAATAATCCTCCCAGAATTGGTTGCTAACCACCTTTTGCGT
GTGCTGCGTTTATGCGAGGG

Product: adenosylmethionine--8-amino-7-oxononanoate transaminase

Products: NA

Alternate protein names: 7,8-diamino-pelargonic acid aminotransferase; DAPA AT; DAPA aminotransferase; Diaminopelargonic acid synthase [H]

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MHHNVHQSEILADPCDLQRAERWRQRDLRVLWHPCTQMREHPDTLPLVPIVRGEGVWLVGHDGRRYLDAVSSWWTNLFGH
ADPRISAAIAAQARTLEHVMLAGFSHEPAVRLAEALLRLAPRQDGREPLSKVFYADNGSAGVEVALKMAFHYFRNRGEEQ
RTRFIALHNGYHGETIGALAVGDIPLYRRVYAPLLTEVLFAPSPDAYLAEPGQSAAEYALQAAEALEALFKRYSGQICAL
ILEPLLQCAGGMRMHHPVYLHRVRELCDAHGALLICDEIATGFGRTGTLFACEQACSAISTDTDDKDLGIMPDLLCLSKG
LTGGFLPLAAVLTTQQLYEEFLDDSRERAFLHSHSYTGNPLACIAALTTLDIFENDCIIERNQVTAARMTQLAASLSGHP
HVADVRQTGMVVAFELTRDGNKRTPFPPQARLGLHVYRAALARGVILRPLGDVVYWMPPYCVDEQQLHLLAETTRVAIDE
AIACV

Sequences:

>Translated_485_residues
MHHNVHQSEILADPCDLQRAERWRQRDLRVLWHPCTQMREHPDTLPLVPIVRGEGVWLVGHDGRRYLDAVSSWWTNLFGH
ADPRISAAIAAQARTLEHVMLAGFSHEPAVRLAEALLRLAPRQDGREPLSKVFYADNGSAGVEVALKMAFHYFRNRGEEQ
RTRFIALHNGYHGETIGALAVGDIPLYRRVYAPLLTEVLFAPSPDAYLAEPGQSAAEYALQAAEALEALFKRYSGQICAL
ILEPLLQCAGGMRMHHPVYLHRVRELCDAHGALLICDEIATGFGRTGTLFACEQACSAISTDTDDKDLGIMPDLLCLSKG
LTGGFLPLAAVLTTQQLYEEFLDDSRERAFLHSHSYTGNPLACIAALTTLDIFENDCIIERNQVTAARMTQLAASLSGHP
HVADVRQTGMVVAFELTRDGNKRTPFPPQARLGLHVYRAALARGVILRPLGDVVYWMPPYCVDEQQLHLLAETTRVAIDE
AIACV
>Mature_485_residues
MHHNVHQSEILADPCDLQRAERWRQRDLRVLWHPCTQMREHPDTLPLVPIVRGEGVWLVGHDGRRYLDAVSSWWTNLFGH
ADPRISAAIAAQARTLEHVMLAGFSHEPAVRLAEALLRLAPRQDGREPLSKVFYADNGSAGVEVALKMAFHYFRNRGEEQ
RTRFIALHNGYHGETIGALAVGDIPLYRRVYAPLLTEVLFAPSPDAYLAEPGQSAAEYALQAAEALEALFKRYSGQICAL
ILEPLLQCAGGMRMHHPVYLHRVRELCDAHGALLICDEIATGFGRTGTLFACEQACSAISTDTDDKDLGIMPDLLCLSKG
LTGGFLPLAAVLTTQQLYEEFLDDSRERAFLHSHSYTGNPLACIAALTTLDIFENDCIIERNQVTAARMTQLAASLSGHP
HVADVRQTGMVVAFELTRDGNKRTPFPPQARLGLHVYRAALARGVILRPLGDVVYWMPPYCVDEQQLHLLAETTRVAIDE
AIACV

Specific function: Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=432, Percent_Identity=25.462962962963, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI13994255, Length=458, Percent_Identity=25.9825327510917, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI226442705, Length=433, Percent_Identity=24.9422632794457, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI226442709, Length=402, Percent_Identity=25.6218905472637, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI4557809, Length=432, Percent_Identity=25.2314814814815, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=24.4019138755981, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI284507298, Length=336, Percent_Identity=24.4047619047619, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1786991, Length=460, Percent_Identity=38.4782608695652, Blast_Score=291, Evalue=6e-80,
Organism=Escherichia coli, GI1789016, Length=435, Percent_Identity=30.5747126436782, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1789759, Length=418, Percent_Identity=28.9473684210526, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI145693181, Length=365, Percent_Identity=30.4109589041096, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1788044, Length=427, Percent_Identity=29.03981264637, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1787560, Length=421, Percent_Identity=28.7410926365796, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786349, Length=325, Percent_Identity=26.4615384615385, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI32564660, Length=457, Percent_Identity=25.8205689277899, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71992977, Length=438, Percent_Identity=23.0593607305936, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=429, Percent_Identity=24.009324009324, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI25144274, Length=305, Percent_Identity=24.5901639344262, Blast_Score=92, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324386, Length=463, Percent_Identity=33.0453563714903, Blast_Score=231, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6323470, Length=448, Percent_Identity=26.1160714285714, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6324432, Length=442, Percent_Identity=23.7556561085973, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI28574759, Length=463, Percent_Identity=28.0777537796976, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI161085790, Length=460, Percent_Identity=28.2608695652174, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21357415, Length=444, Percent_Identity=27.7027027027027, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21356575, Length=425, Percent_Identity=25.4117647058824, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR005815
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.62 [H]

Molecular weight: Translated: 53790; Mature: 53790

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHNVHQSEILADPCDLQRAERWRQRDLRVLWHPCTQMREHPDTLPLVPIVRGEGVWLVG
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEE
HDGRRYLDAVSSWWTNLFGHADPRISAAIAAQARTLEHVMLAGFSHEPAVRLAEALLRLA
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
PRQDGREPLSKVFYADNGSAGVEVALKMAFHYFRNRGEEQRTRFIALHNGYHGETIGALA
CCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHHHEEEEEECCCCCCCCCEEE
VGDIPLYRRVYAPLLTEVLFAPSPDAYLAEPGQSAAEYALQAAEALEALFKRYSGQICAL
ECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
ILEPLLQCAGGMRMHHPVYLHRVRELCDAHGALLICDEIATGFGRTGTLFACEQACSAIS
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHC
TDTDDKDLGIMPDLLCLSKGLTGGFLPLAAVLTTQQLYEEFLDDSRERAFLHSHSYTGNP
CCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCH
LACIAALTTLDIFENDCIIERNQVTAARMTQLAASLSGHPHVADVRQTGMVVAFELTRDG
HHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEEEEECCC
NKRTPFPPQARLGLHVYRAALARGVILRPLGDVVYWMPPYCVDEQQLHLLAETTRVAIDE
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
AIACV
HHHCC
>Mature Secondary Structure
MHHNVHQSEILADPCDLQRAERWRQRDLRVLWHPCTQMREHPDTLPLVPIVRGEGVWLVG
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEE
HDGRRYLDAVSSWWTNLFGHADPRISAAIAAQARTLEHVMLAGFSHEPAVRLAEALLRLA
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
PRQDGREPLSKVFYADNGSAGVEVALKMAFHYFRNRGEEQRTRFIALHNGYHGETIGALA
CCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHHHEEEEEECCCCCCCCCEEE
VGDIPLYRRVYAPLLTEVLFAPSPDAYLAEPGQSAAEYALQAAEALEALFKRYSGQICAL
ECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
ILEPLLQCAGGMRMHHPVYLHRVRELCDAHGALLICDEIATGFGRTGTLFACEQACSAIS
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHC
TDTDDKDLGIMPDLLCLSKGLTGGFLPLAAVLTTQQLYEEFLDDSRERAFLHSHSYTGNP
CCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCH
LACIAALTTLDIFENDCIIERNQVTAARMTQLAASLSGHPHVADVRQTGMVVAFELTRDG
HHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEEEEECCC
NKRTPFPPQARLGLHVYRAALARGVILRPLGDVVYWMPPYCVDEQQLHLLAETTRVAIDE
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
AIACV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2110099 [H]