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The map label for this gene is mrkC [H]

Identifier: 182680623

GI number: 182680623

Start: 78879

End: 81584

Strand: Reverse

Name: mrkC [H]

Synonym: XfasM23_0052

Alternate gene names: 182680623

Gene position: 81584-78879 (Counterclockwise)

Preceding gene: 182680624

Following gene: 182680622

Centisome position: 3.22

GC content: 52.37

Gene sequence:

>2706_bases
ATGAAAAAGCAGGAAATATCGCAACGGAGGAAGGTTGACTCCCTTCAGCTCAGTCGCGTGGAATTCGTCTCAAAATCCGA
GATCGATTCCAACCGTAAGCTGATGGCACCAGAGCTGGATTTAACACAAATCAGAGGGCGCTATTTCAAGCAACGCGTGT
TGGTCGCTGCAATCGCTTCGACTTGCACACTAATGATGTCAAGATTGGCTTGCGCGGAAACGGAGACTGATAATCTTGGA
CAACGCATGCTGGTGGCTAAAGCGGATAACACCGCGCCACAACGTGTAGCGCAAACGGCAAATTTCAACAATAGTTTTCT
GGTTGGCCAAGCGCGTTCCGTTGACTTAGGAATGTTTTCCCGAGGCAATCCTGTTATTGCAGGTCTCTACCGTGCTGACC
TTTATGTAAACGGCCAATGGAAAGGCCGGCGTGATATGGAATTTCGTAATACTAAAGATGACAAGGAAGCTGTCACTTGC
ATGACGCTCGCCATGCTGGATGAACTCGGCATTGATACATCGGCGCTAACAGACTCAGCGGCTGACATGCAGGCCTGCAA
AACCATAGACCAATGGCTGCCGGATGCCTATGCACGTTTCGATGTAGCCACTCAGCGCTTGGACGTAAGCATCCCACAAG
CCGCTATGCGACGCTCAGCACGTGGCTATGTGAGCCCATCACTCTGGGATCATGGTGTCAATGCGGGATTCATCGGCTAT
GCCTTCAACTGGTATGGTGGCCGCAATGCAAATGCAATAAATAGCAGACGGCGTAGTGATTCAGCCTATCTTGGAATCAA
CAGCGGCTTGAATCTAGGCGATTGGCAATTTCGCCATAATTCCAGTTACAGCTGGCATTCCAATGAAGGATCGCTGTGGC
AGAACATTTCCACTTACGCACAACGCGCATTTCCGAACACAAGTAGCATGCTGACAGTAGGCGACGCCTACACCAGCGGC
GAATTATTTGATTCTATCGGTTTCCGTGGTATCAGCTTGGCAACCGATGACCGCATGTTGCCAGACTCGTTACGTGGCTA
TGCGCCTATCGTCCGTGGTATCGCGCAAAGTAATGCGCGTGTGGAGATACACCAGAACGGCCAGTTGATCTACAGCACCA
CGGTTGCGCCCGGGGCGTTCGTCATCGACGATCTATATCCCACCGGCTATGGAGGTGACTTACAGGTCACGGTCTATGAG
ACCGACGGCCGCCAACAGCAGTTCAGTGTCCCCTATGGGTCTGTACCGCAAATGCTCCGAGCGGGGTCGCAGCGGTACAG
CCTAACAGCCGGCAAGATTCGCAATAACAATCTCAGTCATACCCCTTACTTGTTAGAGGGGACGTATCAACGCGGCATTA
GCAACGCACTCACCGCTTATGCAGGCAGCACGATCAGTCAGCGGTACATCGCAGCGATAGCAGGGGCAGGTCTCTCTACC
CCAGTTGGTGCATTTTCCTTGGACGGTACCGTAGCACGCACAAAGCTACGTAACGACACATTTAGCGGTACGAGTCTACG
CTTAAGCTACAGCAAGTTACTGAGCCCAACCAATACCAATATCACACTCGCTGCATATCGGTATTCGACATCAGGCTTTT
ATGGCTTGCAAGAGGCGATCATGGCGATGGACTACGAAAGGCGCGGCCTCAGCACAGCGTCAATTTATAGACAGCGCAGT
CAGCTTCAACTCACTGTGAGCCAACAACTAGGACAGTATGGTTCACTGTACCTGACAGGATCAGCGCGGCAATACTGGAA
CCAACGCGGCAACACGATCCAGTACCAGGGAGGCTACAACGTATCCTATAAGGGCGTGAGTTACGGCCTCTCAGCGTTAC
GCTCACAGATCCCAAGCATGCCCAGCGATACACAGATGCTATTCACAGTATCGGTTCCGCTAGGGAAAGCTTATCCGGTG
ATAGTCACTAGCCAAATCGGTTCACGCGATGGACGCTACGACAACAGCCGCGTAAGCCTAGTGGGAGCTAGCGGCAAAGA
CAGTGCATTAACGTATGGGATAGCCGCATCCGATGCGCGAAACAGCGCCACCATGATCGACGGCAATGTGCAATACCGTA
GCCGCTATGCTGCGCTTTCAGGCAGCTATAGCCATAACCGCAACTATAATCAGATGAGTCTTGGAGCCAGTGGTAGCATT
GTCCTCCACAGCGGAGTTGCGACACTGGCTCCGCAACGCGGTGACACAATGGTTATTATCGAAGCACCGGCAGCCAAGGG
CGCCCGCGTATCCAATATATCCGGCGTGCGCATTGATAGCCGTGGCTATGCCGTCGTACCTTATGTCTCACCGTATCGAA
TGAACACGATCACCCTTGATCCCGAAGGGACAGATCCTGATGTGGAACTGGAAACATCCAGCCAGCTTATCGCTCCCTAT
GCAGGTGCAATCTCCAAAGTGACTTTTGGAACACGGAAGGGCCGCGCATTGATCGTTAATGCACGCACGCCGACTGGTAA
AGCTTTGCCATTCGGTGCACAGGTTATTGATGCCGAAGGACAATCCGTTGGCCTGGTGGCGCAGGGTAGCCTCATCTATA
TACGCGCAAAAGATCCCCAAGGCCGCCTGACCATTAAATGGGGGGATCAGGCGGCACAACAATGCCATTTGGAATATCAA
CTTCCTGCCAACGAAGCTTCGACTCGCCCAAGCAGTTTCACAACTTTGGAAGCCATATGTCGATAA

Upstream 100 bases:

>100_bases
GTGTGTCTTTTACCTACATTAATGATTATGGCGGAATAAAAACGCTCAGCAGTAATTTGGGATCAATGCCTTAACAGCGC
TATTAATAATAAAAAATACT

Downstream 100 bases:

>100_bases
ACAACGGGGTCAGCGCTACTCACACCACGAGATACCAAAAACGGATTTGGAAAGTGGCGGCAGTATGTATGGGGATGCTG
CTAGTATCCAACGCCCAGGC

Product: fimbrial biogenesis outer membrane usher protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 901; Mature: 901

Protein sequence:

>901_residues
MKKQEISQRRKVDSLQLSRVEFVSKSEIDSNRKLMAPELDLTQIRGRYFKQRVLVAAIASTCTLMMSRLACAETETDNLG
QRMLVAKADNTAPQRVAQTANFNNSFLVGQARSVDLGMFSRGNPVIAGLYRADLYVNGQWKGRRDMEFRNTKDDKEAVTC
MTLAMLDELGIDTSALTDSAADMQACKTIDQWLPDAYARFDVATQRLDVSIPQAAMRRSARGYVSPSLWDHGVNAGFIGY
AFNWYGGRNANAINSRRRSDSAYLGINSGLNLGDWQFRHNSSYSWHSNEGSLWQNISTYAQRAFPNTSSMLTVGDAYTSG
ELFDSIGFRGISLATDDRMLPDSLRGYAPIVRGIAQSNARVEIHQNGQLIYSTTVAPGAFVIDDLYPTGYGGDLQVTVYE
TDGRQQQFSVPYGSVPQMLRAGSQRYSLTAGKIRNNNLSHTPYLLEGTYQRGISNALTAYAGSTISQRYIAAIAGAGLST
PVGAFSLDGTVARTKLRNDTFSGTSLRLSYSKLLSPTNTNITLAAYRYSTSGFYGLQEAIMAMDYERRGLSTASIYRQRS
QLQLTVSQQLGQYGSLYLTGSARQYWNQRGNTIQYQGGYNVSYKGVSYGLSALRSQIPSMPSDTQMLFTVSVPLGKAYPV
IVTSQIGSRDGRYDNSRVSLVGASGKDSALTYGIAASDARNSATMIDGNVQYRSRYAALSGSYSHNRNYNQMSLGASGSI
VLHSGVATLAPQRGDTMVIIEAPAAKGARVSNISGVRIDSRGYAVVPYVSPYRMNTITLDPEGTDPDVELETSSQLIAPY
AGAISKVTFGTRKGRALIVNARTPTGKALPFGAQVIDAEGQSVGLVAQGSLIYIRAKDPQGRLTIKWGDQAAQQCHLEYQ
LPANEASTRPSSFTTLEAICR

Sequences:

>Translated_901_residues
MKKQEISQRRKVDSLQLSRVEFVSKSEIDSNRKLMAPELDLTQIRGRYFKQRVLVAAIASTCTLMMSRLACAETETDNLG
QRMLVAKADNTAPQRVAQTANFNNSFLVGQARSVDLGMFSRGNPVIAGLYRADLYVNGQWKGRRDMEFRNTKDDKEAVTC
MTLAMLDELGIDTSALTDSAADMQACKTIDQWLPDAYARFDVATQRLDVSIPQAAMRRSARGYVSPSLWDHGVNAGFIGY
AFNWYGGRNANAINSRRRSDSAYLGINSGLNLGDWQFRHNSSYSWHSNEGSLWQNISTYAQRAFPNTSSMLTVGDAYTSG
ELFDSIGFRGISLATDDRMLPDSLRGYAPIVRGIAQSNARVEIHQNGQLIYSTTVAPGAFVIDDLYPTGYGGDLQVTVYE
TDGRQQQFSVPYGSVPQMLRAGSQRYSLTAGKIRNNNLSHTPYLLEGTYQRGISNALTAYAGSTISQRYIAAIAGAGLST
PVGAFSLDGTVARTKLRNDTFSGTSLRLSYSKLLSPTNTNITLAAYRYSTSGFYGLQEAIMAMDYERRGLSTASIYRQRS
QLQLTVSQQLGQYGSLYLTGSARQYWNQRGNTIQYQGGYNVSYKGVSYGLSALRSQIPSMPSDTQMLFTVSVPLGKAYPV
IVTSQIGSRDGRYDNSRVSLVGASGKDSALTYGIAASDARNSATMIDGNVQYRSRYAALSGSYSHNRNYNQMSLGASGSI
VLHSGVATLAPQRGDTMVIIEAPAAKGARVSNISGVRIDSRGYAVVPYVSPYRMNTITLDPEGTDPDVELETSSQLIAPY
AGAISKVTFGTRKGRALIVNARTPTGKALPFGAQVIDAEGQSVGLVAQGSLIYIRAKDPQGRLTIKWGDQAAQQCHLEYQ
LPANEASTRPSSFTTLEAICR
>Mature_901_residues
MKKQEISQRRKVDSLQLSRVEFVSKSEIDSNRKLMAPELDLTQIRGRYFKQRVLVAAIASTCTLMMSRLACAETETDNLG
QRMLVAKADNTAPQRVAQTANFNNSFLVGQARSVDLGMFSRGNPVIAGLYRADLYVNGQWKGRRDMEFRNTKDDKEAVTC
MTLAMLDELGIDTSALTDSAADMQACKTIDQWLPDAYARFDVATQRLDVSIPQAAMRRSARGYVSPSLWDHGVNAGFIGY
AFNWYGGRNANAINSRRRSDSAYLGINSGLNLGDWQFRHNSSYSWHSNEGSLWQNISTYAQRAFPNTSSMLTVGDAYTSG
ELFDSIGFRGISLATDDRMLPDSLRGYAPIVRGIAQSNARVEIHQNGQLIYSTTVAPGAFVIDDLYPTGYGGDLQVTVYE
TDGRQQQFSVPYGSVPQMLRAGSQRYSLTAGKIRNNNLSHTPYLLEGTYQRGISNALTAYAGSTISQRYIAAIAGAGLST
PVGAFSLDGTVARTKLRNDTFSGTSLRLSYSKLLSPTNTNITLAAYRYSTSGFYGLQEAIMAMDYERRGLSTASIYRQRS
QLQLTVSQQLGQYGSLYLTGSARQYWNQRGNTIQYQGGYNVSYKGVSYGLSALRSQIPSMPSDTQMLFTVSVPLGKAYPV
IVTSQIGSRDGRYDNSRVSLVGASGKDSALTYGIAASDARNSATMIDGNVQYRSRYAALSGSYSHNRNYNQMSLGASGSI
VLHSGVATLAPQRGDTMVIIEAPAAKGARVSNISGVRIDSRGYAVVPYVSPYRMNTITLDPEGTDPDVELETSSQLIAPY
AGAISKVTFGTRKGRALIVNARTPTGKALPFGAQVIDAEGQSVGLVAQGSLIYIRAKDPQGRLTIKWGDQAAQQCHLEYQ
LPANEASTRPSSFTTLEAICR

Specific function: Involved in the export and assembly of the type 3 fimbrial subunit (mrkA) [H]

COG id: COG3188

COG function: function code NU; P pilus assembly protein, porin PapC

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial export usher family [H]

Homologues:

Organism=Escherichia coli, GI1790772, Length=842, Percent_Identity=36.5795724465558, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI1786332, Length=828, Percent_Identity=35.7487922705314, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1787172, Length=825, Percent_Identity=36.1212121212121, Blast_Score=476, Evalue=1e-135,
Organism=Escherichia coli, GI1786744, Length=843, Percent_Identity=34.638196915777, Blast_Score=467, Evalue=1e-132,
Organism=Escherichia coli, GI1789533, Length=789, Percent_Identity=34.4740177439797, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1788427, Length=811, Percent_Identity=30.7028360049322, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI87081778, Length=831, Percent_Identity=27.0758122743682, Blast_Score=221, Evalue=2e-58,
Organism=Escherichia coli, GI1789610, Length=811, Percent_Identity=23.1812577065351, Blast_Score=146, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000015
- InterPro:   IPR018030 [H]

Pfam domain/function: PF00577 Usher [H]

EC number: NA

Molecular weight: Translated: 98295; Mature: 98295

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS01151 FIMBRIAL_USHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQEISQRRKVDSLQLSRVEFVSKSEIDSNRKLMAPELDLTQIRGRYFKQRVLVAAIAS
CCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHH
TCTLMMSRLACAETETDNLGQRMLVAKADNTAPQRVAQTANFNNSFLVGQARSVDLGMFS
HHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCEEEECCCCCEEEEEC
RGNPVIAGLYRADLYVNGQWKGRRDMEFRNTKDDKEAVTCMTLAMLDELGIDTSALTDSA
CCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCH
ADMQACKTIDQWLPDAYARFDVATQRLDVSIPQAAMRRSARGYVSPSLWDHGVNAGFIGY
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHCCCCCCEEEE
AFNWYGGRNANAINSRRRSDSAYLGINSGLNLGDWQFRHNSSYSWHSNEGSLWQNISTYA
EEEECCCCCCCHHHHCCCCCCEEEEECCCCCCCCEEEECCCCCCEECCCCCHHHHHHHHH
QRAFPNTSSMLTVGDAYTSGELFDSIGFRGISLATDDRMLPDSLRGYAPIVRGIAQSNAR
HHHCCCCCCEEEECCCCCCCHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCE
VEIHQNGQLIYSTTVAPGAFVIDDLYPTGYGGDLQVTVYETDGRQQQFSVPYGSVPQMLR
EEEECCCEEEEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEECCCCCCHHHHHH
AGSQRYSLTAGKIRNNNLSHTPYLLEGTYQRGISNALTAYAGSTISQRYIAAIAGAGLST
CCCCEEEEEECCEECCCCCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
PVGAFSLDGTVARTKLRNDTFSGTSLRLSYSKLLSPTNTNITLAAYRYSTSGFYGLQEAI
CCCCEECCCHHEEHEECCCCCCCCEEEEEHHHHCCCCCCCEEEEEEEECCCCCHHHHHHH
MAMDYERRGLSTASIYRQRSQLQLTVSQQLGQYGSLYLTGSARQYWNQRGNTIQYQGGYN
HHHHHHHCCCCHHHHHHHHHHEEEEEHHHCCCCCCEEEECCHHHHHHCCCCEEEECCCCE
VSYKGVSYGLSALRSQIPSMPSDTQMLFTVSVPLGKAYPVIVTSQIGSRDGRYDNSRVSL
EEECHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCEEEE
VGASGKDSALTYGIAASDARNSATMIDGNVQYRSRYAALSGSYSHNRNYNQMSLGASGSI
EECCCCCCEEEEEEEECCCCCCEEEEECCCHHHHEEEEECCCCCCCCCCCEEECCCCCCE
VLHSGVATLAPQRGDTMVIIEAPAAKGARVSNISGVRIDSRGYAVVPYVSPYRMNTITLD
EEECCHHHCCCCCCCEEEEEECCCCCCCEECCCCCEEECCCCCEEEEECCCEEEEEEEEC
PEGTDPDVELETSSQLIAPYAGAISKVTFGTRKGRALIVNARTPTGKALPFGAQVIDAEG
CCCCCCCEEEECCCCEEHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCCCCCEEEECCC
QSVGLVAQGSLIYIRAKDPQGRLTIKWGDQAAQQCHLEYQLPANEASTRPSSFTTLEAIC
CEEEEEECCCEEEEEECCCCCEEEEEECCHHHHHEEEEEECCCCCCCCCCCCCHHHHHHC
R
C
>Mature Secondary Structure
MKKQEISQRRKVDSLQLSRVEFVSKSEIDSNRKLMAPELDLTQIRGRYFKQRVLVAAIAS
CCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHH
TCTLMMSRLACAETETDNLGQRMLVAKADNTAPQRVAQTANFNNSFLVGQARSVDLGMFS
HHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCEEEECCCCCEEEEEC
RGNPVIAGLYRADLYVNGQWKGRRDMEFRNTKDDKEAVTCMTLAMLDELGIDTSALTDSA
CCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCH
ADMQACKTIDQWLPDAYARFDVATQRLDVSIPQAAMRRSARGYVSPSLWDHGVNAGFIGY
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHCCCCCCEEEE
AFNWYGGRNANAINSRRRSDSAYLGINSGLNLGDWQFRHNSSYSWHSNEGSLWQNISTYA
EEEECCCCCCCHHHHCCCCCCEEEEECCCCCCCCEEEECCCCCCEECCCCCHHHHHHHHH
QRAFPNTSSMLTVGDAYTSGELFDSIGFRGISLATDDRMLPDSLRGYAPIVRGIAQSNAR
HHHCCCCCCEEEECCCCCCCHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCE
VEIHQNGQLIYSTTVAPGAFVIDDLYPTGYGGDLQVTVYETDGRQQQFSVPYGSVPQMLR
EEEECCCEEEEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEECCCCCCHHHHHH
AGSQRYSLTAGKIRNNNLSHTPYLLEGTYQRGISNALTAYAGSTISQRYIAAIAGAGLST
CCCCEEEEEECCEECCCCCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
PVGAFSLDGTVARTKLRNDTFSGTSLRLSYSKLLSPTNTNITLAAYRYSTSGFYGLQEAI
CCCCEECCCHHEEHEECCCCCCCCEEEEEHHHHCCCCCCCEEEEEEEECCCCCHHHHHHH
MAMDYERRGLSTASIYRQRSQLQLTVSQQLGQYGSLYLTGSARQYWNQRGNTIQYQGGYN
HHHHHHHCCCCHHHHHHHHHHEEEEEHHHCCCCCCEEEECCHHHHHHCCCCEEEECCCCE
VSYKGVSYGLSALRSQIPSMPSDTQMLFTVSVPLGKAYPVIVTSQIGSRDGRYDNSRVSL
EEECHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCEEEE
VGASGKDSALTYGIAASDARNSATMIDGNVQYRSRYAALSGSYSHNRNYNQMSLGASGSI
EECCCCCCEEEEEEEECCCCCCEEEEECCCHHHHEEEEECCCCCCCCCCCEEECCCCCCE
VLHSGVATLAPQRGDTMVIIEAPAAKGARVSNISGVRIDSRGYAVVPYVSPYRMNTITLD
EEECCHHHCCCCCCCEEEEEECCCCCCCEECCCCCEEECCCCCEEEEECCCEEEEEEEEC
PEGTDPDVELETSSQLIAPYAGAISKVTFGTRKGRALIVNARTPTGKALPFGAQVIDAEG
CCCCCCCEEEECCCCEEHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCCCCCEEEECCC
QSVGLVAQGSLIYIRAKDPQGRLTIKWGDQAAQQCHLEYQLPANEASTRPSSFTTLEAIC
CEEEEEECCCEEEEEECCCCCEEEEEECCHHHHHEEEEEECCCCCCCCCCCCCHHHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1670938 [H]